Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.
Identifieur interne : 002980 ( PubMed/Checkpoint ); précédent : 002979; suivant : 002981Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.
Auteurs : S. Gillessen [Suisse] ; A. Omlin [Suisse] ; G. Attard [Royaume-Uni] ; J S De Bono [Royaume-Uni] ; E. Efstathiou [Grèce] ; K. Fizazi [France] ; S. Halabi ; P S Nelson ; O. Sartor ; M R Smith [États-Unis] ; H R Soule [États-Unis] ; H. Akaza [Japon] ; T M Beer [États-Unis] ; H. Beltran [États-Unis] ; A M Chinnaiyan [États-Unis] ; G. Daugaard [Danemark] ; I D Davis [Australie] ; M. De Santis [Autriche] ; C G Drake [États-Unis] ; R A Eeles [Royaume-Uni] ; S. Fanti [Italie] ; M E Gleave [Canada] ; A. Heidenreich [Allemagne] ; M. Hussain [États-Unis] ; N D James [Royaume-Uni] ; F E Lecouvet [Belgique] ; C J Logothetis [États-Unis] ; K. Mastris [Royaume-Uni] ; S. Nilsson [Suède] ; W K Oh [États-Unis] ; D. Olmos [Espagne] ; A R Padhani ; C. Parker [Royaume-Uni] ; M A Rubin [États-Unis] ; J A Schalken [Pays-Bas] ; H I Scher [États-Unis] ; A. Sella [Israël] ; N D Shore ; E J Small [États-Unis] ; C N Sternberg [Italie] ; H. Suzuki [Japon] ; C J Sweeney [États-Unis] ; I F Tannock [Canada] ; B. Tombal [Belgique]Source :
- Annals of oncology : official journal of the European Society for Medical Oncology [ 1569-8041 ] ; 2015.
Descripteurs français
- KwdFr :
- Adénocarcinome (), Adénocarcinome (anatomopathologie), Agents de maintien de la densité osseuse (usage thérapeutique), Antagonistes des androgènes (usage thérapeutique), Antinéoplasiques (usage thérapeutique), Antinéoplasiques hormonaux (usage thérapeutique), Guides de bonnes pratiques cliniques comme sujet, Humains, Mâle, Orchidectomie, Prostatectomie, Radiothérapie adjuvante, Taxoïdes (usage thérapeutique), Tumeurs de la prostate (), Tumeurs de la prostate (anatomopathologie), Tumeurs prostatiques résistantes à la castration (), Tumeurs prostatiques résistantes à la castration (anatomopathologie).
- MESH :
- anatomopathologie : Adénocarcinome, Tumeurs de la prostate, Tumeurs prostatiques résistantes à la castration.
- usage thérapeutique : Agents de maintien de la densité osseuse, Antagonistes des androgènes, Antinéoplasiques, Antinéoplasiques hormonaux, Taxoïdes.
- Adénocarcinome, Guides de bonnes pratiques cliniques comme sujet, Humains, Mâle, Orchidectomie, Prostatectomie, Radiothérapie adjuvante, Tumeurs de la prostate, Tumeurs prostatiques résistantes à la castration.
English descriptors
- KwdEn :
- Adenocarcinoma (pathology), Adenocarcinoma (therapy), Androgen Antagonists (therapeutic use), Antineoplastic Agents (therapeutic use), Antineoplastic Agents, Hormonal (therapeutic use), Bone Density Conservation Agents (therapeutic use), Humans, Male, Orchiectomy, Practice Guidelines as Topic, Prostatectomy, Prostatic Neoplasms (pathology), Prostatic Neoplasms (therapy), Prostatic Neoplasms, Castration-Resistant (pathology), Prostatic Neoplasms, Castration-Resistant (therapy), Radiotherapy, Adjuvant, Taxoids (therapeutic use).
- MESH :
- chemical , therapeutic use : Androgen Antagonists, Antineoplastic Agents, Antineoplastic Agents, Hormonal, Bone Density Conservation Agents, Taxoids.
- pathology : Adenocarcinoma, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant.
- therapy : Adenocarcinoma, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant.
- Humans, Male, Orchiectomy, Practice Guidelines as Topic, Prostatectomy, Radiotherapy, Adjuvant.
Abstract
The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed the available evidence for the ten most important areas of controversy in advanced prostate cancer (APC) management. The successful registration of several drugs for castration-resistant prostate cancer and the recent studies of chemo-hormonal therapy in men with castration-naïve prostate cancer have led to considerable uncertainty as to the best treatment choices, sequence of treatment options and appropriate patient selection. Management recommendations based on expert opinion, and not based on a critical review of the available evidence, are presented. The various recommendations carried differing degrees of support, as reflected in the wording of the article text and in the detailed voting results recorded in supplementary Material, available at Annals of Oncology online. Detailed decisions on treatment as always will involve consideration of disease extent and location, prior treatments, host factors, patient preferences as well as logistical and economic constraints. Inclusion of men with APC in clinical trials should be encouraged.
DOI: 10.1093/annonc/mdv257
PubMed: 26041764
Affiliations:
- Allemagne, Australie, Autriche, Belgique, Canada, Danemark, Espagne, France, Grèce, Israël, Italie, Japon, Pays-Bas, Royaume-Uni, Suisse, Suède, États-Unis
- Angleterre, Attique (région), Californie, Communauté de Madrid, District de Cologne, Grand Londres, Gueldre, Hovedstaden, Latium, Maryland, Massachusetts, Midlands de l'Ouest, Oregon, Rhénanie-du-Nord-Westphalie, Région de Bruxelles-Capitale, Région de Kantō, Svealand, Texas, Vienne (Autriche), État de New York
- Aix-la-Chapelle, Athènes, Baltimore, Birmingham, Boston, Bruxelles, Copenhague, Houston, Londres, Louvain-la-Neuve, Madrid, Nimègue, Portland, Rome, San Francisco, Stockholm, Tokyo, Vienne (Autriche)
- Université catholique de Louvain, Université de Tokyo
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:26041764Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.</title><author><name sortKey="Gillessen, S" sort="Gillessen, S" uniqKey="Gillessen S" first="S" last="Gillessen">S. Gillessen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen, Switzerland silke.gillessen@kssg.ch.</nlm:affiliation><country wicri:rule="url">Suisse</country><wicri:regionArea>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen</wicri:regionArea><wicri:noRegion>St Gallen</wicri:noRegion></affiliation></author><author><name sortKey="Omlin, A" sort="Omlin, A" uniqKey="Omlin A" first="A" last="Omlin">A. Omlin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen</wicri:regionArea><wicri:noRegion>St Gallen</wicri:noRegion></affiliation></author><author><name sortKey="Attard, G" sort="Attard, G" uniqKey="Attard G" first="G" last="Attard">G. Attard</name><affiliation wicri:level="1"><nlm:affiliation>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="De Bono, J S" sort="De Bono, J S" uniqKey="De Bono J" first="J S" last="De Bono">J S De Bono</name><affiliation wicri:level="1"><nlm:affiliation>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Efstathiou, E" sort="Efstathiou, E" uniqKey="Efstathiou E" first="E" last="Efstathiou">E. Efstathiou</name><affiliation wicri:level="3"><nlm:affiliation>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston, USA Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston, USA Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens Medical School, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Fizazi, K" sort="Fizazi, K" uniqKey="Fizazi K" first="K" last="Fizazi">K. Fizazi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Medicine, Institut Gustave Roussy, University of Paris Sud, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Cancer Medicine, Institut Gustave Roussy, University of Paris Sud, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Halabi, S" sort="Halabi, S" uniqKey="Halabi S" first="S" last="Halabi">S. Halabi</name><affiliation><nlm:affiliation>Department of Biostatistics and Bioinformatics, Duke University, Durham.</nlm:affiliation><wicri:noCountry code="subField">Durham</wicri:noCountry></affiliation></author><author><name sortKey="Nelson, P S" sort="Nelson, P S" uniqKey="Nelson P" first="P S" last="Nelson">P S Nelson</name><affiliation><nlm:affiliation>Division of Human Biology, Fred Hutchinson Cancer Research Centre, Seattle.</nlm:affiliation><wicri:noCountry code="subField">Seattle</wicri:noCountry></affiliation></author><author><name sortKey="Sartor, O" sort="Sartor, O" uniqKey="Sartor O" first="O" last="Sartor">O. Sartor</name><affiliation><nlm:affiliation>Tulane Cancer Centre, Tulane University, New Orleans.</nlm:affiliation><wicri:noCountry code="subField">New Orleans</wicri:noCountry></affiliation></author><author><name sortKey="Smith, M R" sort="Smith, M R" uniqKey="Smith M" first="M R" last="Smith">M R Smith</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital Cancer Centre, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital Cancer Centre</wicri:orgArea></affiliation></author><author><name sortKey="Soule, H R" sort="Soule, H R" uniqKey="Soule H" first="H R" last="Soule">H R Soule</name><affiliation wicri:level="1"><nlm:affiliation>Prostate Cancer Foundation, Santa Monica, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Prostate Cancer Foundation, Santa Monica</wicri:regionArea><wicri:noRegion>Santa Monica</wicri:noRegion></affiliation></author><author><name sortKey="Akaza, H" sort="Akaza, H" uniqKey="Akaza H" first="H" last="Akaza">H. Akaza</name><affiliation wicri:level="4"><nlm:affiliation>Research Centre for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Research Centre for Advanced Science and Technology, The University of Tokyo, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Beer, T M" sort="Beer, T M" uniqKey="Beer T" first="T M" last="Beer">T M Beer</name><affiliation wicri:level="3"><nlm:affiliation>Oregon Health & Science University Knight Cancer Institute, Portland.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Portland</settlement><region type="state">Oregon</region></placeName><wicri:orgArea>Oregon Health & Science University Knight Cancer Institute</wicri:orgArea></affiliation></author><author><name sortKey="Beltran, H" sort="Beltran, H" uniqKey="Beltran H" first="H" last="Beltran">H. Beltran</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Weill Cornell Medical College, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Medicine, Weill Cornell Medical College</wicri:cityArea></affiliation></author><author><name sortKey="Chinnaiyan, A M" sort="Chinnaiyan, A M" uniqKey="Chinnaiyan A" first="A M" last="Chinnaiyan">A M Chinnaiyan</name><affiliation wicri:level="1"><nlm:affiliation>Michigan Centre for Translational Pathology, Department of Pathology Department of Urology, Comprehensive Cancer Centre Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Michigan Centre for Translational Pathology, Department of Pathology Department of Urology, Comprehensive Cancer Centre Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor</wicri:regionArea><wicri:noRegion>Ann Arbor</wicri:noRegion></affiliation></author><author><name sortKey="Daugaard, G" sort="Daugaard, G" uniqKey="Daugaard G" first="G" last="Daugaard">G. Daugaard</name><affiliation wicri:level="3"><nlm:affiliation>Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Davis, I D" sort="Davis, I D" uniqKey="Davis I" first="I D" last="Davis">I D Davis</name><affiliation wicri:level="1"><nlm:affiliation>Monash University and Eastern Health, Eastern Health Clinical School, Box Hill, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash University and Eastern Health, Eastern Health Clinical School, Box Hill</wicri:regionArea><wicri:noRegion>Box Hill</wicri:noRegion></affiliation></author><author><name sortKey="De Santis, M" sort="De Santis, M" uniqKey="De Santis M" first="M" last="De Santis">M. De Santis</name><affiliation wicri:level="3"><nlm:affiliation>Cancer Research Centre, University of Warwick, Warwick, UK Ludwig Boltzmann Institute for Applied Cancer Research, Kaiser Franz Josef-Spital, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Cancer Research Centre, University of Warwick, Warwick, UK Ludwig Boltzmann Institute for Applied Cancer Research, Kaiser Franz Josef-Spital, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Drake, C G" sort="Drake, C G" uniqKey="Drake C" first="C G" last="Drake">C G Drake</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins Sidney Kimmel Cancer Center and The Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Johns Hopkins Sidney Kimmel Cancer Center and The Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore</wicri:regionArea><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Eeles, R A" sort="Eeles, R A" uniqKey="Eeles R" first="R A" last="Eeles">R A Eeles</name><affiliation wicri:level="3"><nlm:affiliation>The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Fanti, S" sort="Fanti, S" uniqKey="Fanti S" first="S" last="Fanti">S. Fanti</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nuclear Medicine, Policlinico S. Orsola, University of Bologna, Bologna, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Nuclear Medicine, Policlinico S. Orsola, University of Bologna, Bologna</wicri:regionArea><wicri:noRegion>Bologna</wicri:noRegion></affiliation></author><author><name sortKey="Gleave, M E" sort="Gleave, M E" uniqKey="Gleave M" first="M E" last="Gleave">M E Gleave</name><affiliation wicri:level="1"><nlm:affiliation>Urological Sciences, Vancouver Prostate Centre, University of British Columbia, Vancouver, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Urological Sciences, Vancouver Prostate Centre, University of British Columbia, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation></author><author><name sortKey="Heidenreich, A" sort="Heidenreich, A" uniqKey="Heidenreich A" first="A" last="Heidenreich">A. Heidenreich</name><affiliation wicri:level="3"><nlm:affiliation>Klinik und Poliklinik für Urologie, RWTH University Aachen, Aachen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinik und Poliklinik für Urologie, RWTH University Aachen, Aachen</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Aix-la-Chapelle</settlement></placeName></affiliation></author><author><name sortKey="Hussain, M" sort="Hussain, M" uniqKey="Hussain M" first="M" last="Hussain">M. Hussain</name><affiliation wicri:level="1"><nlm:affiliation>University of Michigan Comprehensive Cancer Center, Ann Arbor, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, Ann Arbor</wicri:regionArea><wicri:noRegion>Ann Arbor</wicri:noRegion></affiliation></author><author><name sortKey="James, N D" sort="James, N D" uniqKey="James N" first="N D" last="James">N D James</name><affiliation wicri:level="3"><nlm:affiliation>Cancer Research Centre, University of Warwick, Warwick, UK Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham, Birmingham, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cancer Research Centre, University of Warwick, Warwick, UK Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Lecouvet, F E" sort="Lecouvet, F E" uniqKey="Lecouvet F" first="F E" last="Lecouvet">F E Lecouvet</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiology, Centre du Cancer et Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint Luc, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Radiology, Centre du Cancer et Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint Luc, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Logothetis, C J" sort="Logothetis, C J" uniqKey="Logothetis C" first="C J" last="Logothetis">C J Logothetis</name><affiliation wicri:level="3"><nlm:affiliation>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston</wicri:regionArea><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Mastris, K" sort="Mastris, K" uniqKey="Mastris K" first="K" last="Mastris">K. Mastris</name><affiliation wicri:level="1"><nlm:affiliation>Europa Uomo Prostate Patients, Clayhall Ilford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Europa Uomo Prostate Patients, Clayhall Ilford</wicri:regionArea><wicri:noRegion>Clayhall Ilford</wicri:noRegion></affiliation></author><author><name sortKey="Nilsson, S" sort="Nilsson, S" uniqKey="Nilsson S" first="S" last="Nilsson">S. Nilsson</name><affiliation wicri:level="3"><nlm:affiliation>Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology-Pathology, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Oh, W K" sort="Oh, W K" uniqKey="Oh W" first="W K" last="Oh">W K Oh</name><affiliation wicri:level="2"><nlm:affiliation>Division of Haematology and Medical Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Haematology and Medical Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Olmos, D" sort="Olmos, D" uniqKey="Olmos D" first="D" last="Olmos">D. Olmos</name><affiliation wicri:level="3"><nlm:affiliation>Prostate Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid CNIO-IBIMA Genitourinary Cancer Unit, Hospitales Universitarios Virgen de la Victoria y Regional de Málaga, Málaga Centro Integral Oncológico Clara Campal (CIOCC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Prostate Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid CNIO-IBIMA Genitourinary Cancer Unit, Hospitales Universitarios Virgen de la Victoria y Regional de Málaga, Málaga Centro Integral Oncológico Clara Campal (CIOCC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Padhani, A R" sort="Padhani, A R" uniqKey="Padhani A" first="A R" last="Padhani">A R Padhani</name><affiliation><nlm:affiliation>Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Northwood.</nlm:affiliation><wicri:noCountry code="subField">Northwood</wicri:noCountry></affiliation></author><author><name sortKey="Parker, C" sort="Parker, C" uniqKey="Parker C" first="C" last="Parker">C. Parker</name><affiliation wicri:level="1"><nlm:affiliation>Prostate Cancer Targeted Therapy Group, Academic Urology Unit and Department of Diagnostic Radiology, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Prostate Cancer Targeted Therapy Group, Academic Urology Unit and Department of Diagnostic Radiology, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Rubin, M A" sort="Rubin, M A" uniqKey="Rubin M" first="M A" last="Rubin">M A Rubin</name><affiliation wicri:level="2"><nlm:affiliation>Institute for Precision Medicine, Meyer Cancer Center, Department of Pathology and Urology, Weill Cornell Medical College and NewYork Presbyterian, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Precision Medicine, Meyer Cancer Center, Department of Pathology and Urology, Weill Cornell Medical College and NewYork Presbyterian, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Schalken, J A" sort="Schalken, J A" uniqKey="Schalken J" first="J A" last="Schalken">J A Schalken</name><affiliation wicri:level="3"><nlm:affiliation>Department of Urology, Radboud University, Medical Centre, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Urology, Radboud University, Medical Centre, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Scher, H I" sort="Scher, H I" uniqKey="Scher H" first="H I" last="Scher">H I Scher</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Weill Cornell Medical College, New York Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Centre, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Medicine, Weill Cornell Medical College, New York Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Centre</wicri:cityArea></affiliation></author><author><name sortKey="Sella, A" sort="Sella, A" uniqKey="Sella A" first="A" last="Sella">A. Sella</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Assaf Harofeh Medical Centre, Tel-Aviv University, Sackler School of Medicine, Zerifin, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Oncology, Assaf Harofeh Medical Centre, Tel-Aviv University, Sackler School of Medicine, Zerifin</wicri:regionArea><wicri:noRegion>Zerifin</wicri:noRegion></affiliation></author><author><name sortKey="Shore, N D" sort="Shore, N D" uniqKey="Shore N" first="N D" last="Shore">N D Shore</name><affiliation><nlm:affiliation>Department of Urology, Carolina Urologic Research Centre, Myrtle Beach.</nlm:affiliation><wicri:noCountry code="subField">Myrtle Beach</wicri:noCountry></affiliation></author><author><name sortKey="Small, E J" sort="Small, E J" uniqKey="Small E" first="E J" last="Small">E J Small</name><affiliation wicri:level="3"><nlm:affiliation>Helen Diller Family Comprehensive Cancer Centre, UCSF, San Francisco, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Helen Diller Family Comprehensive Cancer Centre, UCSF, San Francisco</wicri:regionArea><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Sternberg, C N" sort="Sternberg, C N" uniqKey="Sternberg C" first="C N" last="Sternberg">C N Sternberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology, San Camillo and Forlanini Hospitals, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Oncology, San Camillo and Forlanini Hospitals, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Suzuki, H" sort="Suzuki, H" uniqKey="Suzuki H" first="H" last="Suzuki">H. Suzuki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Urology, Toho University Sakura Medical Center, Chiba, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Urology, Toho University Sakura Medical Center, Chiba</wicri:regionArea><wicri:noRegion>Chiba</wicri:noRegion></affiliation></author><author><name sortKey="Sweeney, C J" sort="Sweeney, C J" uniqKey="Sweeney C" first="C J" last="Sweeney">C J Sweeney</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston</wicri:regionArea><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Tannock, I F" sort="Tannock, I F" uniqKey="Tannock I" first="I F" last="Tannock">I F Tannock</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Tombal, B" sort="Tombal, B" uniqKey="Tombal B" first="B" last="Tombal">B. Tombal</name><affiliation wicri:level="4"><nlm:affiliation>Service D'Urologie, Institut de Recherche Clinique, Université Catholique de Louvain, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Service D'Urologie, Institut de Recherche Clinique, Université Catholique de Louvain, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region><settlement type="city">Louvain-la-Neuve</settlement></placeName><orgName type="university">Université catholique de Louvain</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26041764</idno><idno type="pmid">26041764</idno><idno type="doi">10.1093/annonc/mdv257</idno><idno type="wicri:Area/PubMed/Corpus">002A66</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002A66</idno><idno type="wicri:Area/PubMed/Curation">002996</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002996</idno><idno type="wicri:Area/PubMed/Checkpoint">002996</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002996</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.</title><author><name sortKey="Gillessen, S" sort="Gillessen, S" uniqKey="Gillessen S" first="S" last="Gillessen">S. Gillessen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen, Switzerland silke.gillessen@kssg.ch.</nlm:affiliation><country wicri:rule="url">Suisse</country><wicri:regionArea>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen</wicri:regionArea><wicri:noRegion>St Gallen</wicri:noRegion></affiliation></author><author><name sortKey="Omlin, A" sort="Omlin, A" uniqKey="Omlin A" first="A" last="Omlin">A. Omlin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen</wicri:regionArea><wicri:noRegion>St Gallen</wicri:noRegion></affiliation></author><author><name sortKey="Attard, G" sort="Attard, G" uniqKey="Attard G" first="G" last="Attard">G. Attard</name><affiliation wicri:level="1"><nlm:affiliation>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="De Bono, J S" sort="De Bono, J S" uniqKey="De Bono J" first="J S" last="De Bono">J S De Bono</name><affiliation wicri:level="1"><nlm:affiliation>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Efstathiou, E" sort="Efstathiou, E" uniqKey="Efstathiou E" first="E" last="Efstathiou">E. Efstathiou</name><affiliation wicri:level="3"><nlm:affiliation>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston, USA Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston, USA Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens Medical School, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Fizazi, K" sort="Fizazi, K" uniqKey="Fizazi K" first="K" last="Fizazi">K. Fizazi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cancer Medicine, Institut Gustave Roussy, University of Paris Sud, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Cancer Medicine, Institut Gustave Roussy, University of Paris Sud, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Halabi, S" sort="Halabi, S" uniqKey="Halabi S" first="S" last="Halabi">S. Halabi</name><affiliation><nlm:affiliation>Department of Biostatistics and Bioinformatics, Duke University, Durham.</nlm:affiliation><wicri:noCountry code="subField">Durham</wicri:noCountry></affiliation></author><author><name sortKey="Nelson, P S" sort="Nelson, P S" uniqKey="Nelson P" first="P S" last="Nelson">P S Nelson</name><affiliation><nlm:affiliation>Division of Human Biology, Fred Hutchinson Cancer Research Centre, Seattle.</nlm:affiliation><wicri:noCountry code="subField">Seattle</wicri:noCountry></affiliation></author><author><name sortKey="Sartor, O" sort="Sartor, O" uniqKey="Sartor O" first="O" last="Sartor">O. Sartor</name><affiliation><nlm:affiliation>Tulane Cancer Centre, Tulane University, New Orleans.</nlm:affiliation><wicri:noCountry code="subField">New Orleans</wicri:noCountry></affiliation></author><author><name sortKey="Smith, M R" sort="Smith, M R" uniqKey="Smith M" first="M R" last="Smith">M R Smith</name><affiliation wicri:level="3"><nlm:affiliation>Massachusetts General Hospital Cancer Centre, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>Massachusetts General Hospital Cancer Centre</wicri:orgArea></affiliation></author><author><name sortKey="Soule, H R" sort="Soule, H R" uniqKey="Soule H" first="H R" last="Soule">H R Soule</name><affiliation wicri:level="1"><nlm:affiliation>Prostate Cancer Foundation, Santa Monica, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Prostate Cancer Foundation, Santa Monica</wicri:regionArea><wicri:noRegion>Santa Monica</wicri:noRegion></affiliation></author><author><name sortKey="Akaza, H" sort="Akaza, H" uniqKey="Akaza H" first="H" last="Akaza">H. Akaza</name><affiliation wicri:level="4"><nlm:affiliation>Research Centre for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Research Centre for Advanced Science and Technology, The University of Tokyo, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Beer, T M" sort="Beer, T M" uniqKey="Beer T" first="T M" last="Beer">T M Beer</name><affiliation wicri:level="3"><nlm:affiliation>Oregon Health & Science University Knight Cancer Institute, Portland.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Portland</settlement><region type="state">Oregon</region></placeName><wicri:orgArea>Oregon Health & Science University Knight Cancer Institute</wicri:orgArea></affiliation></author><author><name sortKey="Beltran, H" sort="Beltran, H" uniqKey="Beltran H" first="H" last="Beltran">H. Beltran</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Weill Cornell Medical College, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Medicine, Weill Cornell Medical College</wicri:cityArea></affiliation></author><author><name sortKey="Chinnaiyan, A M" sort="Chinnaiyan, A M" uniqKey="Chinnaiyan A" first="A M" last="Chinnaiyan">A M Chinnaiyan</name><affiliation wicri:level="1"><nlm:affiliation>Michigan Centre for Translational Pathology, Department of Pathology Department of Urology, Comprehensive Cancer Centre Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Michigan Centre for Translational Pathology, Department of Pathology Department of Urology, Comprehensive Cancer Centre Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor</wicri:regionArea><wicri:noRegion>Ann Arbor</wicri:noRegion></affiliation></author><author><name sortKey="Daugaard, G" sort="Daugaard, G" uniqKey="Daugaard G" first="G" last="Daugaard">G. Daugaard</name><affiliation wicri:level="3"><nlm:affiliation>Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Davis, I D" sort="Davis, I D" uniqKey="Davis I" first="I D" last="Davis">I D Davis</name><affiliation wicri:level="1"><nlm:affiliation>Monash University and Eastern Health, Eastern Health Clinical School, Box Hill, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash University and Eastern Health, Eastern Health Clinical School, Box Hill</wicri:regionArea><wicri:noRegion>Box Hill</wicri:noRegion></affiliation></author><author><name sortKey="De Santis, M" sort="De Santis, M" uniqKey="De Santis M" first="M" last="De Santis">M. De Santis</name><affiliation wicri:level="3"><nlm:affiliation>Cancer Research Centre, University of Warwick, Warwick, UK Ludwig Boltzmann Institute for Applied Cancer Research, Kaiser Franz Josef-Spital, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Cancer Research Centre, University of Warwick, Warwick, UK Ludwig Boltzmann Institute for Applied Cancer Research, Kaiser Franz Josef-Spital, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Drake, C G" sort="Drake, C G" uniqKey="Drake C" first="C G" last="Drake">C G Drake</name><affiliation wicri:level="3"><nlm:affiliation>Johns Hopkins Sidney Kimmel Cancer Center and The Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Johns Hopkins Sidney Kimmel Cancer Center and The Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore</wicri:regionArea><placeName><settlement type="city">Baltimore</settlement><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Eeles, R A" sort="Eeles, R A" uniqKey="Eeles R" first="R A" last="Eeles">R A Eeles</name><affiliation wicri:level="3"><nlm:affiliation>The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Fanti, S" sort="Fanti, S" uniqKey="Fanti S" first="S" last="Fanti">S. Fanti</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nuclear Medicine, Policlinico S. Orsola, University of Bologna, Bologna, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Nuclear Medicine, Policlinico S. Orsola, University of Bologna, Bologna</wicri:regionArea><wicri:noRegion>Bologna</wicri:noRegion></affiliation></author><author><name sortKey="Gleave, M E" sort="Gleave, M E" uniqKey="Gleave M" first="M E" last="Gleave">M E Gleave</name><affiliation wicri:level="1"><nlm:affiliation>Urological Sciences, Vancouver Prostate Centre, University of British Columbia, Vancouver, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Urological Sciences, Vancouver Prostate Centre, University of British Columbia, Vancouver</wicri:regionArea><wicri:noRegion>Vancouver</wicri:noRegion></affiliation></author><author><name sortKey="Heidenreich, A" sort="Heidenreich, A" uniqKey="Heidenreich A" first="A" last="Heidenreich">A. Heidenreich</name><affiliation wicri:level="3"><nlm:affiliation>Klinik und Poliklinik für Urologie, RWTH University Aachen, Aachen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinik und Poliklinik für Urologie, RWTH University Aachen, Aachen</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Aix-la-Chapelle</settlement></placeName></affiliation></author><author><name sortKey="Hussain, M" sort="Hussain, M" uniqKey="Hussain M" first="M" last="Hussain">M. Hussain</name><affiliation wicri:level="1"><nlm:affiliation>University of Michigan Comprehensive Cancer Center, Ann Arbor, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Michigan Comprehensive Cancer Center, Ann Arbor</wicri:regionArea><wicri:noRegion>Ann Arbor</wicri:noRegion></affiliation></author><author><name sortKey="James, N D" sort="James, N D" uniqKey="James N" first="N D" last="James">N D James</name><affiliation wicri:level="3"><nlm:affiliation>Cancer Research Centre, University of Warwick, Warwick, UK Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham, Birmingham, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cancer Research Centre, University of Warwick, Warwick, UK Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region></placeName></affiliation></author><author><name sortKey="Lecouvet, F E" sort="Lecouvet, F E" uniqKey="Lecouvet F" first="F E" last="Lecouvet">F E Lecouvet</name><affiliation wicri:level="3"><nlm:affiliation>Department of Radiology, Centre du Cancer et Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint Luc, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Radiology, Centre du Cancer et Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint Luc, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Logothetis, C J" sort="Logothetis, C J" uniqKey="Logothetis C" first="C J" last="Logothetis">C J Logothetis</name><affiliation wicri:level="3"><nlm:affiliation>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston</wicri:regionArea><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Mastris, K" sort="Mastris, K" uniqKey="Mastris K" first="K" last="Mastris">K. Mastris</name><affiliation wicri:level="1"><nlm:affiliation>Europa Uomo Prostate Patients, Clayhall Ilford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Europa Uomo Prostate Patients, Clayhall Ilford</wicri:regionArea><wicri:noRegion>Clayhall Ilford</wicri:noRegion></affiliation></author><author><name sortKey="Nilsson, S" sort="Nilsson, S" uniqKey="Nilsson S" first="S" last="Nilsson">S. Nilsson</name><affiliation wicri:level="3"><nlm:affiliation>Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology-Pathology, Karolinska Institutet, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Oh, W K" sort="Oh, W K" uniqKey="Oh W" first="W K" last="Oh">W K Oh</name><affiliation wicri:level="2"><nlm:affiliation>Division of Haematology and Medical Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Haematology and Medical Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Olmos, D" sort="Olmos, D" uniqKey="Olmos D" first="D" last="Olmos">D. Olmos</name><affiliation wicri:level="3"><nlm:affiliation>Prostate Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid CNIO-IBIMA Genitourinary Cancer Unit, Hospitales Universitarios Virgen de la Victoria y Regional de Málaga, Málaga Centro Integral Oncológico Clara Campal (CIOCC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Prostate Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid CNIO-IBIMA Genitourinary Cancer Unit, Hospitales Universitarios Virgen de la Victoria y Regional de Málaga, Málaga Centro Integral Oncológico Clara Campal (CIOCC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Padhani, A R" sort="Padhani, A R" uniqKey="Padhani A" first="A R" last="Padhani">A R Padhani</name><affiliation><nlm:affiliation>Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Northwood.</nlm:affiliation><wicri:noCountry code="subField">Northwood</wicri:noCountry></affiliation></author><author><name sortKey="Parker, C" sort="Parker, C" uniqKey="Parker C" first="C" last="Parker">C. Parker</name><affiliation wicri:level="1"><nlm:affiliation>Prostate Cancer Targeted Therapy Group, Academic Urology Unit and Department of Diagnostic Radiology, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Prostate Cancer Targeted Therapy Group, Academic Urology Unit and Department of Diagnostic Radiology, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton</wicri:regionArea><wicri:noRegion>Sutton</wicri:noRegion></affiliation></author><author><name sortKey="Rubin, M A" sort="Rubin, M A" uniqKey="Rubin M" first="M A" last="Rubin">M A Rubin</name><affiliation wicri:level="2"><nlm:affiliation>Institute for Precision Medicine, Meyer Cancer Center, Department of Pathology and Urology, Weill Cornell Medical College and NewYork Presbyterian, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Precision Medicine, Meyer Cancer Center, Department of Pathology and Urology, Weill Cornell Medical College and NewYork Presbyterian, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Schalken, J A" sort="Schalken, J A" uniqKey="Schalken J" first="J A" last="Schalken">J A Schalken</name><affiliation wicri:level="3"><nlm:affiliation>Department of Urology, Radboud University, Medical Centre, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Urology, Radboud University, Medical Centre, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Scher, H I" sort="Scher, H I" uniqKey="Scher H" first="H I" last="Scher">H I Scher</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Weill Cornell Medical College, New York Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Centre, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Medicine, Weill Cornell Medical College, New York Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Centre</wicri:cityArea></affiliation></author><author><name sortKey="Sella, A" sort="Sella, A" uniqKey="Sella A" first="A" last="Sella">A. Sella</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Assaf Harofeh Medical Centre, Tel-Aviv University, Sackler School of Medicine, Zerifin, Israel.</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Oncology, Assaf Harofeh Medical Centre, Tel-Aviv University, Sackler School of Medicine, Zerifin</wicri:regionArea><wicri:noRegion>Zerifin</wicri:noRegion></affiliation></author><author><name sortKey="Shore, N D" sort="Shore, N D" uniqKey="Shore N" first="N D" last="Shore">N D Shore</name><affiliation><nlm:affiliation>Department of Urology, Carolina Urologic Research Centre, Myrtle Beach.</nlm:affiliation><wicri:noCountry code="subField">Myrtle Beach</wicri:noCountry></affiliation></author><author><name sortKey="Small, E J" sort="Small, E J" uniqKey="Small E" first="E J" last="Small">E J Small</name><affiliation wicri:level="3"><nlm:affiliation>Helen Diller Family Comprehensive Cancer Centre, UCSF, San Francisco, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Helen Diller Family Comprehensive Cancer Centre, UCSF, San Francisco</wicri:regionArea><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Sternberg, C N" sort="Sternberg, C N" uniqKey="Sternberg C" first="C N" last="Sternberg">C N Sternberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology, San Camillo and Forlanini Hospitals, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Oncology, San Camillo and Forlanini Hospitals, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Suzuki, H" sort="Suzuki, H" uniqKey="Suzuki H" first="H" last="Suzuki">H. Suzuki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Urology, Toho University Sakura Medical Center, Chiba, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Urology, Toho University Sakura Medical Center, Chiba</wicri:regionArea><wicri:noRegion>Chiba</wicri:noRegion></affiliation></author><author><name sortKey="Sweeney, C J" sort="Sweeney, C J" uniqKey="Sweeney C" first="C J" last="Sweeney">C J Sweeney</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston</wicri:regionArea><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Tannock, I F" sort="Tannock, I F" uniqKey="Tannock I" first="I F" last="Tannock">I F Tannock</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Tombal, B" sort="Tombal, B" uniqKey="Tombal B" first="B" last="Tombal">B. Tombal</name><affiliation wicri:level="4"><nlm:affiliation>Service D'Urologie, Institut de Recherche Clinique, Université Catholique de Louvain, Brussels, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Service D'Urologie, Institut de Recherche Clinique, Université Catholique de Louvain, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region><settlement type="city">Louvain-la-Neuve</settlement></placeName><orgName type="university">Université catholique de Louvain</orgName></affiliation></author></analytic><series><title level="j">Annals of oncology : official journal of the European Society for Medical Oncology</title><idno type="eISSN">1569-8041</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenocarcinoma (pathology)</term><term>Adenocarcinoma (therapy)</term><term>Androgen Antagonists (therapeutic use)</term><term>Antineoplastic Agents (therapeutic use)</term><term>Antineoplastic Agents, Hormonal (therapeutic use)</term><term>Bone Density Conservation Agents (therapeutic use)</term><term>Humans</term><term>Male</term><term>Orchiectomy</term><term>Practice Guidelines as Topic</term><term>Prostatectomy</term><term>Prostatic Neoplasms (pathology)</term><term>Prostatic Neoplasms (therapy)</term><term>Prostatic Neoplasms, Castration-Resistant (pathology)</term><term>Prostatic Neoplasms, Castration-Resistant (therapy)</term><term>Radiotherapy, Adjuvant</term><term>Taxoids (therapeutic use)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adénocarcinome ()</term><term>Adénocarcinome (anatomopathologie)</term><term>Agents de maintien de la densité osseuse (usage thérapeutique)</term><term>Antagonistes des androgènes (usage thérapeutique)</term><term>Antinéoplasiques (usage thérapeutique)</term><term>Antinéoplasiques hormonaux (usage thérapeutique)</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Mâle</term><term>Orchidectomie</term><term>Prostatectomie</term><term>Radiothérapie adjuvante</term><term>Taxoïdes (usage thérapeutique)</term><term>Tumeurs de la prostate ()</term><term>Tumeurs de la prostate (anatomopathologie)</term><term>Tumeurs prostatiques résistantes à la castration ()</term><term>Tumeurs prostatiques résistantes à la castration (anatomopathologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Androgen Antagonists</term><term>Antineoplastic Agents</term><term>Antineoplastic Agents, Hormonal</term><term>Bone Density Conservation Agents</term><term>Taxoids</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Adénocarcinome</term><term>Tumeurs de la prostate</term><term>Tumeurs prostatiques résistantes à la castration</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Adenocarcinoma</term><term>Prostatic Neoplasms</term><term>Prostatic Neoplasms, Castration-Resistant</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Adenocarcinoma</term><term>Prostatic Neoplasms</term><term>Prostatic Neoplasms, Castration-Resistant</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Agents de maintien de la densité osseuse</term><term>Antagonistes des androgènes</term><term>Antinéoplasiques</term><term>Antinéoplasiques hormonaux</term><term>Taxoïdes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Male</term><term>Orchiectomy</term><term>Practice Guidelines as Topic</term><term>Prostatectomy</term><term>Radiotherapy, Adjuvant</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adénocarcinome</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Mâle</term><term>Orchidectomie</term><term>Prostatectomie</term><term>Radiothérapie adjuvante</term><term>Tumeurs de la prostate</term><term>Tumeurs prostatiques résistantes à la castration</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed the available evidence for the ten most important areas of controversy in advanced prostate cancer (APC) management. The successful registration of several drugs for castration-resistant prostate cancer and the recent studies of chemo-hormonal therapy in men with castration-naïve prostate cancer have led to considerable uncertainty as to the best treatment choices, sequence of treatment options and appropriate patient selection. Management recommendations based on expert opinion, and not based on a critical review of the available evidence, are presented. The various recommendations carried differing degrees of support, as reflected in the wording of the article text and in the detailed voting results recorded in supplementary Material, available at Annals of Oncology online. Detailed decisions on treatment as always will involve consideration of disease extent and location, prior treatments, host factors, patient preferences as well as logistical and economic constraints. Inclusion of men with APC in clinical trials should be encouraged.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26041764</PMID><DateCreated><Year>2015</Year><Month>07</Month><Day>23</Day></DateCreated><DateCompleted><Year>2016</Year><Month>04</Month><Day>21</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1569-8041</ISSN><JournalIssue CitedMedium="Internet"><Volume>26</Volume><Issue>8</Issue><PubDate><Year>2015</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Annals of oncology : official journal of the European Society for Medical Oncology</Title><ISOAbbreviation>Ann. Oncol.</ISOAbbreviation></Journal><ArticleTitle>Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.</ArticleTitle><Pagination><MedlinePgn>1589-604</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/annonc/mdv257</ELocationID><Abstract><AbstractText>The first St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) Expert Panel identified and reviewed the available evidence for the ten most important areas of controversy in advanced prostate cancer (APC) management. The successful registration of several drugs for castration-resistant prostate cancer and the recent studies of chemo-hormonal therapy in men with castration-naïve prostate cancer have led to considerable uncertainty as to the best treatment choices, sequence of treatment options and appropriate patient selection. Management recommendations based on expert opinion, and not based on a critical review of the available evidence, are presented. The various recommendations carried differing degrees of support, as reflected in the wording of the article text and in the detailed voting results recorded in supplementary Material, available at Annals of Oncology online. Detailed decisions on treatment as always will involve consideration of disease extent and location, prior treatments, host factors, patient preferences as well as logistical and economic constraints. Inclusion of men with APC in clinical trials should be encouraged.</AbstractText><CopyrightInformation>© The Author 2015. Published by Oxford University Press on behalf of the European Society for Medical Oncology.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gillessen</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen, Switzerland silke.gillessen@kssg.ch.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Omlin</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Oncology/Haematology, Kantonsspital St Gallen, St Gallen, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Attard</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Bono</LastName><ForeName>J S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Prostate Cancer Targeted Therapy Group and Drug Development Unit, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Efstathiou</LastName><ForeName>E</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston, USA Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fizazi</LastName><ForeName>K</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Cancer Medicine, Institut Gustave Roussy, University of Paris Sud, Villejuif, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Halabi</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Biostatistics and Bioinformatics, Duke University, Durham.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nelson</LastName><ForeName>P S</ForeName><Initials>PS</Initials><AffiliationInfo><Affiliation>Division of Human Biology, Fred Hutchinson Cancer Research Centre, Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sartor</LastName><ForeName>O</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Tulane Cancer Centre, Tulane University, New Orleans.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>M R</ForeName><Initials>MR</Initials><AffiliationInfo><Affiliation>Massachusetts General Hospital Cancer Centre, Boston.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soule</LastName><ForeName>H R</ForeName><Initials>HR</Initials><AffiliationInfo><Affiliation>Prostate Cancer Foundation, Santa Monica, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Akaza</LastName><ForeName>H</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Research Centre for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Beer</LastName><ForeName>T M</ForeName><Initials>TM</Initials><AffiliationInfo><Affiliation>Oregon Health & Science University Knight Cancer Institute, Portland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Beltran</LastName><ForeName>H</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Medicine, Weill Cornell Medical College, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chinnaiyan</LastName><ForeName>A M</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Michigan Centre for Translational Pathology, Department of Pathology Department of Urology, Comprehensive Cancer Centre Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Daugaard</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Davis</LastName><ForeName>I D</ForeName><Initials>ID</Initials><AffiliationInfo><Affiliation>Monash University and Eastern Health, Eastern Health Clinical School, Box Hill, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Santis</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Cancer Research Centre, University of Warwick, Warwick, UK Ludwig Boltzmann Institute for Applied Cancer Research, Kaiser Franz Josef-Spital, Vienna, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Drake</LastName><ForeName>C G</ForeName><Initials>CG</Initials><AffiliationInfo><Affiliation>Johns Hopkins Sidney Kimmel Cancer Center and The Brady Urological Institute, Department of Urology, Johns Hopkins University School of Medicine, Baltimore, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eeles</LastName><ForeName>R A</ForeName><Initials>RA</Initials><AffiliationInfo><Affiliation>The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fanti</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Nuclear Medicine, Policlinico S. Orsola, University of Bologna, Bologna, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gleave</LastName><ForeName>M E</ForeName><Initials>ME</Initials><AffiliationInfo><Affiliation>Urological Sciences, Vancouver Prostate Centre, University of British Columbia, Vancouver, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Heidenreich</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Klinik und Poliklinik für Urologie, RWTH University Aachen, Aachen, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hussain</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University of Michigan Comprehensive Cancer Center, Ann Arbor, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>James</LastName><ForeName>N D</ForeName><Initials>ND</Initials><AffiliationInfo><Affiliation>Cancer Research Centre, University of Warwick, Warwick, UK Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham, Birmingham, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lecouvet</LastName><ForeName>F E</ForeName><Initials>FE</Initials><AffiliationInfo><Affiliation>Department of Radiology, Centre du Cancer et Institut de Recherche Expérimentale et Clinique (IREC), Cliniques Universitaires Saint Luc, Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Logothetis</LastName><ForeName>C J</ForeName><Initials>CJ</Initials><AffiliationInfo><Affiliation>Department of Genitourinary Medical Oncology, MD Anderson Cancer Centre, Houston Department of Genitourinary Medical Oncology, David H. Koch Centre, The University of Texas M. D. Anderson Cancer Centre, Houston, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mastris</LastName><ForeName>K</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Europa Uomo Prostate Patients, Clayhall Ilford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nilsson</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oh</LastName><ForeName>W K</ForeName><Initials>WK</Initials><AffiliationInfo><Affiliation>Division of Haematology and Medical Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olmos</LastName><ForeName>D</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Prostate Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid CNIO-IBIMA Genitourinary Cancer Unit, Hospitales Universitarios Virgen de la Victoria y Regional de Málaga, Málaga Centro Integral Oncológico Clara Campal (CIOCC), Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Padhani</LastName><ForeName>A R</ForeName><Initials>AR</Initials><AffiliationInfo><Affiliation>Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Northwood.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Parker</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Prostate Cancer Targeted Therapy Group, Academic Urology Unit and Department of Diagnostic Radiology, The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, Sutton, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rubin</LastName><ForeName>M A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Institute for Precision Medicine, Meyer Cancer Center, Department of Pathology and Urology, Weill Cornell Medical College and NewYork Presbyterian, New York, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schalken</LastName><ForeName>J A</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>Department of Urology, Radboud University, Medical Centre, Nijmegen, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Scher</LastName><ForeName>H I</ForeName><Initials>HI</Initials><AffiliationInfo><Affiliation>Department of Medicine, Weill Cornell Medical College, New York Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Centre, New York.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sella</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Oncology, Assaf Harofeh Medical Centre, Tel-Aviv University, Sackler School of Medicine, Zerifin, Israel.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shore</LastName><ForeName>N D</ForeName><Initials>ND</Initials><AffiliationInfo><Affiliation>Department of Urology, Carolina Urologic Research Centre, Myrtle Beach.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Small</LastName><ForeName>E J</ForeName><Initials>EJ</Initials><AffiliationInfo><Affiliation>Helen Diller Family Comprehensive Cancer Centre, UCSF, San Francisco, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sternberg</LastName><ForeName>C N</ForeName><Initials>CN</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, San Camillo and Forlanini Hospitals, Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Suzuki</LastName><ForeName>H</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Urology, Toho University Sakura Medical Center, Chiba, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sweeney</LastName><ForeName>C J</ForeName><Initials>CJ</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tannock</LastName><ForeName>I F</ForeName><Initials>IF</Initials><AffiliationInfo><Affiliation>Department of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tombal</LastName><ForeName>B</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Service D'Urologie, Institut de Recherche Clinique, Université Catholique de Louvain, Brussels, Belgium.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>K24 CA121990</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>PG12-49</GrantID><Agency>Prostate Cancer UK</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016446">Consensus Development Conference</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>06</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Ann Oncol</MedlineTA><NlmUniqueID>9007735</NlmUniqueID><ISSNLinking>0923-7534</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000726">Androgen Antagonists</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000970">Antineoplastic Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018931">Antineoplastic Agents, Hormonal</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D050071">Bone Density Conservation Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D043823">Taxoids</NameOfSubstance></Chemical><Chemical><RegistryNumber>15H5577CQD</RegistryNumber><NameOfSubstance UI="C067311">docetaxel</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Ann Oncol. 2015 Nov;26(11):2354</RefSource><PMID Version="1">26216387</PMID></CommentsCorrections><CommentsCorrections RefType="CommentIn"><RefSource>Ann Oncol. 2015 Nov;26(11):2354-5</RefSource><PMID Version="1">26347101</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Urology. 1997 Jan;49(1):71-8</RefSource><PMID Version="1">9000189</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 1998 Oct 8;339(15):1036-42</RefSource><PMID Version="1">9761805</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Urology. 2014 Mar;83(3):664-9</RefSource><PMID Version="1">24411213</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 1982 Mar;79(5):1658-62</RefSource><PMID Version="1">6461861</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Oncol (R Coll Radiol). 2007 Sep;19(7):528-31</RefSource><PMID Version="1">17499490</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2015 Jan;67(1):53-60</RefSource><PMID Version="1">24882673</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Genitourin Cancer. 2014 Dec;12(6):428-32</RefSource><PMID Version="1">25066221</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BJU Int. 2016 Jan;117(1):102-9</RefSource><PMID Version="1">25238114</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Oncol. 2008 Jul;19(7):1308-11</RefSource><PMID Version="1">18356135</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Oncol. 2013 Jun 1;31(16):2029-36</RefSource><PMID Version="1">23630216</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Magn Reson Imaging. 2014 May;39(5):1049-78</RefSource><PMID Version="1">24510426</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Urol. 2003 Jan;169(1):164-9</RefSource><PMID Version="1">12478127</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2015 May;67(5):852-63</RefSource><PMID Version="1">25240974</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer. 2013 Oct 15;119(20):3636-43</RefSource><PMID Version="1">23913744</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Surg. 1945 Dec;122(6):1031-41</RefSource><PMID Version="1">17858696</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Oncol. 2013 Jul;24(7):1802-7</RefSource><PMID Version="1">23585511</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Urology. 1995 Aug;46(2):220-6</RefSource><PMID Version="1">7624991</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Radiology. 2013 Dec;269(3):816-23</RefSource><PMID Version="1">23925271</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Oncol. 2014 Sep;15(10):1147-56</RefSource><PMID Version="1">25104109</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Cancer. 2014 Oct;50(15):2519-31</RefSource><PMID Version="1">25139492</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2015 Aug;68(2):317-24</RefSource><PMID Version="1">25108579</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer. 2001 Jul 15;92(2):303-10</RefSource><PMID Version="1">11466683</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Cancer. 2014 Jun;50(9):1602-9</RefSource><PMID Version="1">24725337</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2012 Sep 27;367(13):1187-97</RefSource><PMID Version="1">22894553</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2014 Oct;66(4):e71-2</RefSource><PMID Version="1">25012524</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Oncol. 2008 Mar 1;26(7):1148-59</RefSource><PMID Version="1">18309951</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br J Urol. 1991 May;67(5):502-8</RefSource><PMID Version="1">1828183</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Radiol. 2013 Jul;23(7):1986-97</RefSource><PMID Version="1">23455764</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Nucl Med. 2013 May;38(5):305-14</RefSource><PMID Version="1">23486334</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Skeletal Radiol. 2014 Nov;43(11):1503-13</RefSource><PMID Version="1">24841276</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2010 Oct 2;376(9747):1147-54</RefSource><PMID Version="1">20888992</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Oncol. 2013 Sep;24(9):2206-23</RefSource><PMID Version="1">23917950</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2012 Jan 7;379(9810):39-46</RefSource><PMID Version="1">22093187</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Prostate. 2014 Sep;74(13):1278-85</RefSource><PMID Version="1">25053178</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2015 Jun;67(6):1028-38</RefSource><PMID Version="1">25301760</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Genitourin Cancer. 2015 Feb;13(1):39-43</RefSource><PMID Version="1">24999168</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Urol. 2011 Sep;186(3):889-97</RefSource><PMID Version="1">21788033</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Natl Cancer Inst. 2002 Oct 2;94(19):1458-68</RefSource><PMID Version="1">12359855</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BJU Int. 2014 Dec;114(6):818-23</RefSource><PMID Version="1">24314065</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Cancer Res. 2014 Jun 1;20(11):2846-50</RefSource><PMID Version="1">24727321</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Urology. 2014 May;83(5):1122-8</RefSource><PMID Version="1">24661333</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Oncol. 2013 Feb;14(2):149-58</RefSource><PMID Version="1">23306100</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Oncol. 2012 Feb 20;30(6):637-43</RefSource><PMID Version="1">22184395</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Oncol. 2013 Jul;24(7):1807-12</RefSource><PMID Version="1">23576708</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer. 2002 Jul 15;95(2):361-76</RefSource><PMID Version="1">12124837</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Oncol. 2012 Nov;23(11):2943-7</RefSource><PMID Version="1">22771826</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Oncol. 2014 Jun;15(7):738-46</RefSource><PMID Version="1">24836273</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2012 Mar;61(3):549-59</RefSource><PMID Version="1">22099611</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 1998;34 Suppl 3:37-41</RefSource><PMID Version="1">9854195</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2012 Jul;62(1):68-75</RefSource><PMID Version="1">22366187</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Oncol. 2012 Dec;13(12):1210-7</RefSource><PMID Version="1">23142059</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2014 Sep;66(3):459-65</RefSource><PMID Version="1">24411987</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Cancer Res. 2011 Jul 15;17(14):4854-61</RefSource><PMID Version="1">21632851</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Oncol. 2013 Oct 20;31(30):3800-6</RefSource><PMID Version="1">24043751</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BJU Int. 2008 Dec;102(11):1531-8</RefSource><PMID Version="1">19035858</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Biomed Res Int. 2014;2014:316272</RefSource><PMID Version="1">24967355</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2014 Jul 31;371(5):424-33</RefSource><PMID Version="1">24881730</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2014;9(4):e91779</RefSource><PMID Version="1">24710083</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2011 May 26;364(21):1995-2005</RefSource><PMID Version="1">21612468</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Natl Cancer Inst. 2004 Jun 2;96(11):879-82</RefSource><PMID Version="1">15173273</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Oncol (R Coll Radiol). 2013 Apr;25(4):252-64</RefSource><PMID Version="1">23313568</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Genitourin Cancer. 2015 Jun;13(3):193-8</RefSource><PMID Version="1">25466676</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2013 Jan 10;368(2):138-48</RefSource><PMID Version="1">23228172</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2015 Apr;67(4):795-802</RefSource><PMID Version="1">25454616</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Prostate Cancer Prostatic Dis. 2013 Jun;16(2):187-92</RefSource><PMID Version="1">23381694</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Oncol. 2013 Nov;24(11):2881-6</RefSource><PMID Version="1">23946329</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Oncol. 2004 Mar 15;22(6):1025-33</RefSource><PMID Version="1">15020604</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2011 Mar 5;377(9768):813-22</RefSource><PMID Version="1">21353695</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Invest Med. 1982;5(4):267-75</RefSource><PMID Version="1">6819101</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Prostate. 2005 Oct 1;65(2):178-87</RefSource><PMID Version="1">15948151</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2013 Jul 18;369(3):213-23</RefSource><PMID Version="1">23863050</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer. 2008 Nov 1;113(9):2478-87</RefSource><PMID Version="1">18785254</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Oncol. 2015 Apr 20;33(12):1356-63</RefSource><PMID Version="1">25624432</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Acta Radiol. 2011 Jun 1;52(5):557-61</RefSource><PMID Version="1">21498309</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2010 Jul 29;363(5):411-22</RefSource><PMID Version="1">20818862</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Prostate Cancer Prostatic Dis. 2014 Mar;17(1):23-7</RefSource><PMID Version="1">24366412</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Prostate Cancer Prostatic Dis. 2015 Jun;18(2):122-7</RefSource><PMID Version="1">25600186</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer. 1993 May 1;71(9):2782-90</RefSource><PMID Version="1">7682149</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Oncol. 2014 Apr 10;32(11):1143-50</RefSource><PMID Version="1">24590644</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2000 Apr 29;355(9214):1491-8</RefSource><PMID Version="1">10801170</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer. 1986 Dec 1;58(11):2546-50</RefSource><PMID Version="1">2429759</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cancer. 2009 Aug 1;115(15):3437-45</RefSource><PMID Version="1">19536889</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Urol. 2014 Feb;65(2):270-3</RefSource><PMID Version="1">24295792</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000230" MajorTopicYN="N">Adenocarcinoma</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000726" MajorTopicYN="N">Androgen Antagonists</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000970" MajorTopicYN="N">Antineoplastic Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018931" MajorTopicYN="N">Antineoplastic Agents, Hormonal</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D050071" MajorTopicYN="N">Bone Density Conservation Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009919" MajorTopicYN="N">Orchiectomy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017410" MajorTopicYN="N">Practice Guidelines as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011468" MajorTopicYN="N">Prostatectomy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011471" MajorTopicYN="N">Prostatic Neoplasms</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D064129" MajorTopicYN="N">Prostatic Neoplasms, Castration-Resistant</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018714" MajorTopicYN="N">Radiotherapy, Adjuvant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D043823" MajorTopicYN="N">Taxoids</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC4511225</OtherID><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">advanced prostate cancer</Keyword><Keyword MajorTopicYN="N">castration-naïve prostate cancer</Keyword><Keyword MajorTopicYN="N">castration-resistant prostate cancer</Keyword><Keyword MajorTopicYN="N">consensus</Keyword><Keyword MajorTopicYN="N">therapeutics</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>05</Month><Day>05</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>05</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>6</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>6</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>4</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26041764</ArticleId><ArticleId IdType="pii">mdv257</ArticleId><ArticleId IdType="doi">10.1093/annonc/mdv257</ArticleId><ArticleId IdType="pmc">PMC4511225</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>Danemark</li><li>Espagne</li><li>France</li><li>Grèce</li><li>Israël</li><li>Italie</li><li>Japon</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Attique (région)</li><li>Californie</li><li>Communauté de Madrid</li><li>District de Cologne</li><li>Grand Londres</li><li>Gueldre</li><li>Hovedstaden</li><li>Latium</li><li>Maryland</li><li>Massachusetts</li><li>Midlands de l'Ouest</li><li>Oregon</li><li>Rhénanie-du-Nord-Westphalie</li><li>Région de Bruxelles-Capitale</li><li>Région de Kantō</li><li>Svealand</li><li>Texas</li><li>Vienne (Autriche)</li><li>État de New York</li></region><settlement><li>Aix-la-Chapelle</li><li>Athènes</li><li>Baltimore</li><li>Birmingham</li><li>Boston</li><li>Bruxelles</li><li>Copenhague</li><li>Houston</li><li>Londres</li><li>Louvain-la-Neuve</li><li>Madrid</li><li>Nimègue</li><li>Portland</li><li>Rome</li><li>San Francisco</li><li>Stockholm</li><li>Tokyo</li><li>Vienne (Autriche)</li></settlement><orgName><li>Université catholique de Louvain</li><li>Université de Tokyo</li></orgName></list><tree><noCountry><name sortKey="Halabi, S" sort="Halabi, S" uniqKey="Halabi S" first="S" last="Halabi">S. Halabi</name><name sortKey="Nelson, P S" sort="Nelson, P S" uniqKey="Nelson P" first="P S" last="Nelson">P S Nelson</name><name sortKey="Padhani, A R" sort="Padhani, A R" uniqKey="Padhani A" first="A R" last="Padhani">A R Padhani</name><name sortKey="Sartor, O" sort="Sartor, O" uniqKey="Sartor O" first="O" last="Sartor">O. Sartor</name><name sortKey="Shore, N D" sort="Shore, N D" uniqKey="Shore N" first="N D" last="Shore">N D Shore</name></noCountry><country name="Suisse"><noRegion><name sortKey="Gillessen, S" sort="Gillessen, S" uniqKey="Gillessen S" first="S" last="Gillessen">S. Gillessen</name></noRegion><name sortKey="Omlin, A" sort="Omlin, A" uniqKey="Omlin A" first="A" last="Omlin">A. Omlin</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Attard, G" sort="Attard, G" uniqKey="Attard G" first="G" last="Attard">G. Attard</name></noRegion><name sortKey="De Bono, J S" sort="De Bono, J S" uniqKey="De Bono J" first="J S" last="De Bono">J S De Bono</name><name sortKey="Eeles, R A" sort="Eeles, R A" uniqKey="Eeles R" first="R A" last="Eeles">R A Eeles</name><name sortKey="James, N D" sort="James, N D" uniqKey="James N" first="N D" last="James">N D James</name><name sortKey="Mastris, K" sort="Mastris, K" uniqKey="Mastris K" first="K" last="Mastris">K. Mastris</name><name sortKey="Parker, C" sort="Parker, C" uniqKey="Parker C" first="C" last="Parker">C. Parker</name></country><country name="Grèce"><region name="Attique (région)"><name sortKey="Efstathiou, E" sort="Efstathiou, E" uniqKey="Efstathiou E" first="E" last="Efstathiou">E. Efstathiou</name></region></country><country name="France"><noRegion><name sortKey="Fizazi, K" sort="Fizazi, K" uniqKey="Fizazi K" first="K" last="Fizazi">K. Fizazi</name></noRegion></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Smith, M R" sort="Smith, M R" uniqKey="Smith M" first="M R" last="Smith">M R Smith</name></region><name sortKey="Beer, T M" sort="Beer, T M" uniqKey="Beer T" first="T M" last="Beer">T M Beer</name><name sortKey="Beltran, H" sort="Beltran, H" uniqKey="Beltran H" first="H" last="Beltran">H. Beltran</name><name sortKey="Chinnaiyan, A M" sort="Chinnaiyan, A M" uniqKey="Chinnaiyan A" first="A M" last="Chinnaiyan">A M Chinnaiyan</name><name sortKey="Drake, C G" sort="Drake, C G" uniqKey="Drake C" first="C G" last="Drake">C G Drake</name><name sortKey="Hussain, M" sort="Hussain, M" uniqKey="Hussain M" first="M" last="Hussain">M. Hussain</name><name sortKey="Logothetis, C J" sort="Logothetis, C J" uniqKey="Logothetis C" first="C J" last="Logothetis">C J Logothetis</name><name sortKey="Oh, W K" sort="Oh, W K" uniqKey="Oh W" first="W K" last="Oh">W K Oh</name><name sortKey="Rubin, M A" sort="Rubin, M A" uniqKey="Rubin M" first="M A" last="Rubin">M A Rubin</name><name sortKey="Scher, H I" sort="Scher, H I" uniqKey="Scher H" first="H I" last="Scher">H I Scher</name><name sortKey="Small, E J" sort="Small, E J" uniqKey="Small E" first="E J" last="Small">E J Small</name><name sortKey="Soule, H R" sort="Soule, H R" uniqKey="Soule H" first="H R" last="Soule">H R Soule</name><name sortKey="Sweeney, C J" sort="Sweeney, C J" uniqKey="Sweeney C" first="C J" last="Sweeney">C J Sweeney</name></country><country name="Japon"><region name="Région de Kantō"><name sortKey="Akaza, H" sort="Akaza, H" uniqKey="Akaza H" first="H" last="Akaza">H. Akaza</name></region><name sortKey="Suzuki, H" sort="Suzuki, H" uniqKey="Suzuki H" first="H" last="Suzuki">H. Suzuki</name></country><country name="Danemark"><region name="Hovedstaden"><name sortKey="Daugaard, G" sort="Daugaard, G" uniqKey="Daugaard G" first="G" last="Daugaard">G. Daugaard</name></region></country><country name="Australie"><noRegion><name sortKey="Davis, I D" sort="Davis, I D" uniqKey="Davis I" first="I D" last="Davis">I D Davis</name></noRegion></country><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="De Santis, M" sort="De Santis, M" uniqKey="De Santis M" first="M" last="De Santis">M. De Santis</name></region></country><country name="Italie"><noRegion><name sortKey="Fanti, S" sort="Fanti, S" uniqKey="Fanti S" first="S" last="Fanti">S. Fanti</name></noRegion><name sortKey="Sternberg, C N" sort="Sternberg, C N" uniqKey="Sternberg C" first="C N" last="Sternberg">C N Sternberg</name></country><country name="Canada"><noRegion><name sortKey="Gleave, M E" sort="Gleave, M E" uniqKey="Gleave M" first="M E" last="Gleave">M E Gleave</name></noRegion><name sortKey="Tannock, I F" sort="Tannock, I F" uniqKey="Tannock I" first="I F" last="Tannock">I F Tannock</name></country><country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Heidenreich, A" sort="Heidenreich, A" uniqKey="Heidenreich A" first="A" last="Heidenreich">A. Heidenreich</name></region></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Lecouvet, F E" sort="Lecouvet, F E" uniqKey="Lecouvet F" first="F E" last="Lecouvet">F E Lecouvet</name></region><name sortKey="Tombal, B" sort="Tombal, B" uniqKey="Tombal B" first="B" last="Tombal">B. Tombal</name></country><country name="Suède"><region name="Svealand"><name sortKey="Nilsson, S" sort="Nilsson, S" uniqKey="Nilsson S" first="S" last="Nilsson">S. Nilsson</name></region></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Olmos, D" sort="Olmos, D" uniqKey="Olmos D" first="D" last="Olmos">D. Olmos</name></region></country><country name="Pays-Bas"><region name="Gueldre"><name sortKey="Schalken, J A" sort="Schalken, J A" uniqKey="Schalken J" first="J A" last="Schalken">J A Schalken</name></region></country><country name="Israël"><noRegion><name sortKey="Sella, A" sort="Sella, A" uniqKey="Sella A" first="A" last="Sella">A. Sella</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002980 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 002980 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:26041764
|texte= Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:26041764" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |