A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
Identifieur interne : 002424 ( PubMed/Checkpoint ); précédent : 002423; suivant : 002425A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
Auteurs : Paul S. De Vries ; Daniel I. Chasman [États-Unis] ; Maria Sabater-Lleal ; Ming-Huei Chen [États-Unis] ; Jennifer E. Huffman ; Maristella Steri [Italie] ; Weihong Tang ; Alexander Teumer ; Riccardo E. Marioni [Australie] ; Vera Grossmann ; Jouke J. Hottenga [Pays-Bas] ; Stella Trompet ; Martina Müller-Nurasyid ; Jing Hua Zhao ; Jennifer A. Brody ; Marcus E. Kleber [Allemagne] ; Xiuqing Guo [États-Unis] ; Jie Jin Wang [Australie] ; Paul L. Auer [États-Unis] ; John R. Attia ; Lisa R. Yanek [États-Unis] ; Tarunveer S. Ahluwalia [Danemark] ; Jari Lahti [Finlande] ; Cristina Venturini [Royaume-Uni] ; Toshiko Tanaka [États-Unis] ; Lawrence F. Bielak [États-Unis] ; Peter K. Joshi ; Ares Rocanin-Arjo [France] ; Ivana Kolcic ; Pau Navarro ; Lynda M. Rose [États-Unis] ; Christopher Oldmeadow ; Helene Riess ; Johanna Mazur ; Saonli Basu [États-Unis] ; Anuj Goel [Royaume-Uni] ; Qiong Yang [États-Unis] ; Mohsen Ghanbari [Iran] ; Gonneke Willemsen [Pays-Bas] ; Ann Rumley ; Edoardo Fiorillo [Italie] ; Anton J M. De Craen ; Anne Grotevendt ; Robert Scott ; Kent D. Taylor ; Graciela E. Delgado [Allemagne] ; Jie Yao ; Annette Kifley [Australie] ; Charles Kooperberg [États-Unis] ; Rehan Qayyum [États-Unis] ; Lorna M. Lopez [Irlande (pays)] ; Tina L. Berentzen [Danemark] ; Katri R Ikkönen ; Massimo Mangino [Royaume-Uni] ; Stefania Bandinelli [Italie] ; Patricia A. Peyser [États-Unis] ; Sarah Wild ; David-Alexandre Trégouët [France] ; Alan F. Wright ; Jonathan Marten ; Tatijana Zemunik ; Alanna C. Morrison [États-Unis] ; Bengt Sennblad [Suède] ; Geoffrey Tofler [Australie] ; Moniek P M. De Maat ; Eco J C. De Geus [Pays-Bas] ; Gordon D. Lowe ; Magdalena Zoledziewska [Italie] ; Naveed Sattar [Royaume-Uni] ; Harald Binder ; Uwe Völker ; Melanie Waldenberger [Allemagne] ; Kay-Tee Khaw [Royaume-Uni] ; Barbara Mcknight ; Jie Huang [Royaume-Uni] ; Nancy S. Jenny ; Elizabeth G. Holliday ; Lihong Qi [États-Unis] ; Mark G. Mcevoy [Australie] ; Diane M. Becker [États-Unis] ; John M. Starr ; Antti-Pekka Sarin [Finlande] ; Pirro G. Hysi [Royaume-Uni] ; Dena G. Hernandez [États-Unis] ; Min A. Jhun [États-Unis] ; Harry Campbell ; Anders Hamsten ; Fernando Rivadeneira [Pays-Bas] ; Wendy L. Mcardle [Royaume-Uni] ; P Eline Slagboom [Pays-Bas] ; Tanja Zeller [Allemagne] ; Wolfgang Koenig [Allemagne] ; Bruce M. Psaty [États-Unis] ; Talin Haritunians [États-Unis] ; Jingmin Liu [États-Unis] ; Aarno Palotie ; André G. Uitterlinden [Pays-Bas] ; David J. Stott [Royaume-Uni] ; Albert Hofman ; Oscar H. Franco ; Ozren Polasek [Croatie] ; Igor Rudan ; Pierre-Emmanuel Morange [France] ; James F. Wilson ; Sharon L R. Kardia [États-Unis] ; Luigi Ferrucci [États-Unis] ; Tim D. Spector [Royaume-Uni] ; Johan G. Eriksson [Finlande] ; Torben Hansen ; Ian J. Deary [Royaume-Uni] ; Lewis C. Becker [États-Unis] ; Rodney J. Scott [Australie] ; Paul Mitchell [Australie] ; Winfried M Rz [Autriche] ; Nick J. Wareham ; Annette Peters ; Andreas Greinacher [Allemagne] ; Philipp S. Wild [Allemagne] ; J Wouter Jukema [Pays-Bas] ; Dorret I. Boomsma [Pays-Bas] ; Caroline Hayward ; Francesco Cucca [Italie] ; Russell Tracy [États-Unis] ; Hugh Watkins [Royaume-Uni] ; Alex P. Reiner [États-Unis] ; Aaron R. Folsom ; Paul M. Ridker [États-Unis] ; Christopher J. O'Donnell [États-Unis] ; Nicholas L. Smith [États-Unis] ; David P. Strachan [Royaume-Uni] ; Abbas Dehghan [Pays-Bas]Source :
- Human molecular genetics [ 1460-2083 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Fibrinogen.
- genetics : European Continental Ancestry Group, Fibrinogen.
- Adult, Aged, Aged, 80 and over, Female, Genetic Loci, Genome-Wide Association Study, Humans, INDEL Mutation, Male, Middle Aged, Polymorphism, Single Nucleotide.
Abstract
Genome-wide association studies have previously identified 23 genetic loci associated with circulating fibrinogen concentration. These studies used HapMap imputation and did not examine the X-chromosome. 1000 Genomes imputation provides better coverage of uncommon variants, and includes indels. We conducted a genome-wide association analysis of 34 studies imputed to the 1000 Genomes Project reference panel and including ∼120 000 participants of European ancestry (95 806 participants with data on the X-chromosome). Approximately 10.7 million single-nucleotide polymorphisms and 1.2 million indels were examined. We identified 41 genome-wide significant fibrinogen loci; of which, 18 were newly identified. There were no genome-wide significant signals on the X-chromosome. The lead variants of five significant loci were indels. We further identified six additional independent signals, including three rare variants, at two previously characterized loci: FGB and IRF1. Together the 41 loci explain 3% of the variance in plasma fibrinogen concentration.
DOI: 10.1093/hmg/ddv454
PubMed: 26561523
Affiliations:
- Allemagne, Australie, Autriche, Croatie, Danemark, Finlande, France, Iran, Irlande (pays), Italie, Pays-Bas, Royaume-Uni, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Bade-Wurtemberg, Bavière, Californie, District de Haute-Bavière, District de Karlsruhe, Grand Londres, Hambourg, Hollande-Méridionale, Hollande-Septentrionale, Hovedstaden, Maryland, Massachusetts, Michigan, Minnesota, Nouvelle-Galles du Sud, Oxfordshire, Provence-Alpes-Côte d'Azur, Rhénanie-Palatinat, Svealand, Texas, Utrecht (province), Uusimaa, Vermont, Washington (État), Wisconsin, Écosse, Île-de-France
- Amsterdam, Cambridge, Copenhague, Glasgow, Hambourg, Helsinki, Leyde, Londres, Mannheim, Marseille, Mayence, Munich, Oxford, Rotterdam, Seattle, Stockholm, Sydney, Utrecht, Édimbourg
- Université d'Helsinki, Université d'Oxford, Université d'Édimbourg, Université de Cambridge, Université de Glasgow, Université de Londres, Université de Sydney, Université de Washington
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pubmed:26561523Le document en format XML
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<author><name sortKey="Ahluwalia, Tarunveer S" sort="Ahluwalia, Tarunveer S" uniqKey="Ahluwalia T" first="Tarunveer S" last="Ahluwalia">Tarunveer S. Ahluwalia</name>
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<author><name sortKey="Venturini, Cristina" sort="Venturini, Cristina" uniqKey="Venturini C" first="Cristina" last="Venturini">Cristina Venturini</name>
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<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Opthalmology, UCL, London, UK, Department of Twin Research and Genetic Epidemiology, Kings College London, London</wicri:regionArea>
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<author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name>
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<author><name sortKey="Bielak, Lawrence F" sort="Bielak, Lawrence F" uniqKey="Bielak L" first="Lawrence F" last="Bielak">Lawrence F. Bielak</name>
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<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
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<author><name sortKey="Joshi, Peter K" sort="Joshi, Peter K" uniqKey="Joshi P" first="Peter K" last="Joshi">Peter K. Joshi</name>
<affiliation><nlm:affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
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<author><name sortKey="Rocanin Arjo, Ares" sort="Rocanin Arjo, Ares" uniqKey="Rocanin Arjo A" first="Ares" last="Rocanin-Arjo">Ares Rocanin-Arjo</name>
<affiliation wicri:level="3"><nlm:affiliation>Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1166, Paris F-75013, France, Sorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris F-75013, France, Institute for Cardiometabolism and Nutrition (ICAN), Paris F-75013, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1166, Paris F-75013, France, Sorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris F-75013, France, Institute for Cardiometabolism and Nutrition (ICAN), Paris F-75013</wicri:regionArea>
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<author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name>
<affiliation><nlm:affiliation>Department of Public Health, Faculty of Medicine.</nlm:affiliation>
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</affiliation>
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<author><name sortKey="Navarro, Pau" sort="Navarro, Pau" uniqKey="Navarro P" first="Pau" last="Navarro">Pau Navarro</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</nlm:affiliation>
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<author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name>
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<wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA</wicri:regionArea>
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<author><name sortKey="Oldmeadow, Christopher" sort="Oldmeadow, Christopher" uniqKey="Oldmeadow C" first="Christopher" last="Oldmeadow">Christopher Oldmeadow</name>
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<author><name sortKey="Riess, Helene" sort="Riess, Helene" uniqKey="Riess H" first="Helene" last="Riess">Helene Riess</name>
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<author><name sortKey="Mazur, Johanna" sort="Mazur, Johanna" uniqKey="Mazur J" first="Johanna" last="Mazur">Johanna Mazur</name>
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</author>
<author><name sortKey="Basu, Saonli" sort="Basu, Saonli" uniqKey="Basu S" first="Saonli" last="Basu">Saonli Basu</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Biostatistics, University of Minnesota, Minneapolis, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Biostatistics, University of Minnesota, Minneapolis, MN</wicri:regionArea>
<placeName><region type="state">Minnesota</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name>
<affiliation wicri:level="4"><nlm:affiliation>Cardiovascular Medicine Department/Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cardiovascular Medicine Department/Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author><name sortKey="Yang, Qiong" sort="Yang, Qiong" uniqKey="Yang Q" first="Qiong" last="Yang">Qiong Yang</name>
<affiliation wicri:level="2"><nlm:affiliation>Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA, USA, Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA, USA, Department of Biostatistics, Boston University School of Public Health, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ghanbari, Mohsen" sort="Ghanbari, Mohsen" uniqKey="Ghanbari M" first="Mohsen" last="Ghanbari">Mohsen Ghanbari</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Department of Epidemiology, Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad</wicri:regionArea>
<wicri:noRegion>Mashhad</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rumley, Ann" sort="Rumley, Ann" uniqKey="Rumley A" first="Ann" last="Rumley">Ann Rumley</name>
<affiliation><nlm:affiliation>Institute of Cardiovascular and Medical Sciences and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Cardiovascular and Medical Sciences and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fiorillo, Edoardo" sort="Fiorillo, Edoardo" uniqKey="Fiorillo E" first="Edoardo" last="Fiorillo">Edoardo Fiorillo</name>
<affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari</wicri:regionArea>
<wicri:noRegion>Cagliari</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Craen, Anton J M" sort="De Craen, Anton J M" uniqKey="De Craen A" first="Anton J M" last="De Craen">Anton J M. De Craen</name>
<affiliation><nlm:affiliation>Department of Gerontology and Geriatrics and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Gerontology and Geriatrics and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Grotevendt, Anne" sort="Grotevendt, Anne" uniqKey="Grotevendt A" first="Anne" last="Grotevendt">Anne Grotevendt</name>
<affiliation><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Clinical Chemistry and Laboratory Medicine.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Scott, Robert" sort="Scott, Robert" uniqKey="Scott R" first="Robert" last="Scott">Robert Scott</name>
<affiliation><nlm:affiliation>MRC Epidemiology Unit, School of Clinical Medicine and.</nlm:affiliation>
<wicri:noCountry code="subField">School of Clinical Medicine and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Taylor, Kent D" sort="Taylor, Kent D" uniqKey="Taylor K" first="Kent D" last="Taylor">Kent D. Taylor</name>
<affiliation><nlm:affiliation>Institute for Translational Genomics and Population Sciences and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute for Translational Genomics and Population Sciences and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Delgado, Graciela E" sort="Delgado, Graciela E" uniqKey="Delgado G" first="Graciela E" last="Delgado">Graciela E. Delgado</name>
<affiliation wicri:level="3"><nlm:affiliation>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Mannheim</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yao, Jie" sort="Yao, Jie" uniqKey="Yao J" first="Jie" last="Yao">Jie Yao</name>
<affiliation><nlm:affiliation>Institute for Translational Genomics and Population Sciences and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute for Translational Genomics and Population Sciences and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kifley, Annette" sort="Kifley, Annette" uniqKey="Kifley A" first="Annette" last="Kifley">Annette Kifley</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
</placeName>
<orgName type="university">Université de Sydney</orgName>
</affiliation>
</author>
<author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name>
<affiliation wicri:level="2"><nlm:affiliation>Fred Hutchinson Cancer Research Center, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Qayyum, Rehan" sort="Qayyum, Rehan" uniqKey="Qayyum R" first="Rehan" last="Qayyum">Rehan Qayyum</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland, University College Dublin, UCD Conway Institute, Centre for Proteome Research, UCD, Belfield, Dublin, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland, University College Dublin, UCD Conway Institute, Centre for Proteome Research, UCD, Belfield, Dublin</wicri:regionArea>
<wicri:noRegion>Dublin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berentzen, Tina L" sort="Berentzen, Tina L" uniqKey="Berentzen T" first="Tina L" last="Berentzen">Tina L. Berentzen</name>
<affiliation wicri:level="3"><nlm:affiliation>Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="R Ikkonen, Katri" sort="R Ikkonen, Katri" uniqKey="R Ikkonen K" first="Katri" last="R Ikkönen">Katri R Ikkönen</name>
<affiliation><nlm:affiliation>Institute of Behavioural Sciences.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Behavioural Sciences.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, Kings College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name>
<affiliation wicri:level="1"><nlm:affiliation>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence</wicri:regionArea>
<wicri:noRegion>Florence</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Peyser, Patricia A" sort="Peyser, Patricia A" uniqKey="Peyser P" first="Patricia A" last="Peyser">Patricia A. Peyser</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wild, Sarah" sort="Wild, Sarah" uniqKey="Wild S" first="Sarah" last="Wild">Sarah Wild</name>
<affiliation><nlm:affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Trégouët">David-Alexandre Trégouët</name>
<affiliation wicri:level="3"><nlm:affiliation>Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1166, Paris F-75013, France, Sorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris F-75013, France, Institute for Cardiometabolism and Nutrition (ICAN), Paris F-75013, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1166, Paris F-75013, France, Sorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris F-75013, France, Institute for Cardiometabolism and Nutrition (ICAN), Paris F-75013</wicri:regionArea>
<placeName><region type="region" nuts="2">Île-de-France</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</nlm:affiliation>
<wicri:noCountry code="subField">Institute of Genetics and Molecular Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Marten, Jonathan" sort="Marten, Jonathan" uniqKey="Marten J" first="Jonathan" last="Marten">Jonathan Marten</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</nlm:affiliation>
<wicri:noCountry code="subField">Institute of Genetics and Molecular Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name>
<affiliation><nlm:affiliation>Department of Biology, School of Medicine and.</nlm:affiliation>
<wicri:noCountry code="subField">School of Medicine and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name>
<affiliation wicri:level="2"><nlm:affiliation>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit and Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit and Science for Life Laboratory, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tofler, Geoffrey" sort="Tofler, Geoffrey" uniqKey="Tofler G" first="Geoffrey" last="Tofler">Geoffrey Tofler</name>
<affiliation wicri:level="3"><nlm:affiliation>Royal North Shore Hospital, Sydney University, Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Royal North Shore Hospital, Sydney University, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Maat, Moniek P M" sort="De Maat, Moniek P M" uniqKey="De Maat M" first="Moniek P M" last="De Maat">Moniek P M. De Maat</name>
<affiliation><nlm:affiliation>Department of Hematology and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Hematology and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J C" last="De Geus">Eco J C. De Geus</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands, EMGO+ institute, VU University & VU Medical Center, Amsterdam.</nlm:affiliation>
<country>Pays-Bas</country>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
<wicri:orgArea>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands, EMGO+ institute, VU University & VU Medical Center</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Lowe, Gordon D" sort="Lowe, Gordon D" uniqKey="Lowe G" first="Gordon D" last="Lowe">Gordon D. Lowe</name>
<affiliation><nlm:affiliation>Institute of Cardiovascular and Medical Sciences and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Cardiovascular and Medical Sciences and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Zoledziewska, Magdalena" sort="Zoledziewska, Magdalena" uniqKey="Zoledziewska M" first="Magdalena" last="Zoledziewska">Magdalena Zoledziewska</name>
<affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari</wicri:regionArea>
<wicri:noRegion>Cagliari</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, Glasgow, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, Glasgow</wicri:regionArea>
<wicri:noRegion>Glasgow</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Binder, Harald" sort="Binder, Harald" uniqKey="Binder H" first="Harald" last="Binder">Harald Binder</name>
<affiliation><nlm:affiliation>Institute of Medical Biostatistics, Epidemiology and Informatics and.</nlm:affiliation>
<wicri:noCountry code="subField">Epidemiology and Informatics and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name>
<affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics and.</nlm:affiliation>
<wicri:noCountry code="no comma">Interfaculty Institute for Genetics and Functional Genomics and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II and Research Unit of Molecular Epidemiology, Helmholtz ZentrumMünchen - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II and Research Unit of Molecular Epidemiology, Helmholtz ZentrumMünchen - German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name>
<affiliation wicri:level="4"><nlm:affiliation>Clinical Gerontology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Clinical Gerontology Unit, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name>
<affiliation><nlm:affiliation>Department of Biostatistics.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Biostatistics.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Huang, Jie" sort="Huang, Jie" uniqKey="Huang J" first="Jie" last="Huang">Jie Huang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jenny, Nancy S" sort="Jenny, Nancy S" uniqKey="Jenny N" first="Nancy S" last="Jenny">Nancy S. Jenny</name>
<affiliation><nlm:affiliation>Department of Pathology and Laboratory Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Pathology and Laboratory Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Holliday, Elizabeth G" sort="Holliday, Elizabeth G" uniqKey="Holliday E" first="Elizabeth G" last="Holliday">Elizabeth G. Holliday</name>
<affiliation><nlm:affiliation>Public Health Stream, Hunter Medical Research Institute, School of Medicine and Public Health and.</nlm:affiliation>
<wicri:noCountry code="subField">School of Medicine and Public Health and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Qi, Lihong" sort="Qi, Lihong" uniqKey="Qi L" first="Lihong" last="Qi">Lihong Qi</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Biostatistics, Department of Public Health Sciences, UC Davis, Davis, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Biostatistics, Department of Public Health Sciences, UC Davis, Davis, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcevoy, Mark G" sort="Mcevoy, Mark G" uniqKey="Mcevoy M" first="Mark G" last="Mcevoy">Mark G. Mcevoy</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Medicine and Public Health, University of Newcastle, Newcastle, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Medicine and Public Health, University of Newcastle, Newcastle</wicri:regionArea>
<wicri:noRegion>Newcastle</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Becker, Diane M" sort="Becker, Diane M" uniqKey="Becker D" first="Diane M" last="Becker">Diane M. Becker</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name>
<affiliation><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, Alzheimer Scotland Dementia Research Centre and.</nlm:affiliation>
<wicri:noCountry code="subField">Alzheimer Scotland Dementia Research Centre and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Sarin, Antti Pekka" sort="Sarin, Antti Pekka" uniqKey="Sarin A" first="Antti-Pekka" last="Sarin">Antti-Pekka Sarin</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Molecular Medicine Finland (FIMM) and Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland (FIMM) and Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, Kings College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hernandez, Dena G" sort="Hernandez, Dena G" uniqKey="Hernandez D" first="Dena G" last="Hernandez">Dena G. Hernandez</name>
<affiliation wicri:level="2"><nlm:affiliation>Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jhun, Min A" sort="Jhun, Min A" uniqKey="Jhun M" first="Min A" last="Jhun">Min A. Jhun</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name>
<affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name>
<affiliation><nlm:affiliation>Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit and.</nlm:affiliation>
<wicri:noCountry code="subField">Atherosclerosis Research Unit and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea>
<wicri:noRegion>Bristol</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Slagboom, P Eline" sort="Slagboom, P Eline" uniqKey="Slagboom P" first="P Eline" last="Slagboom">P Eline Slagboom</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zeller, Tanja" sort="Zeller, Tanja" uniqKey="Zeller T" first="Tanja" last="Zeller">Tanja Zeller</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of General and Interventional Cardiology, University Heart Centre, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Cardiovascular Research (DZHK), Partner Site Hamburg, Lübeck, Kiel, Hamburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of General and Interventional Cardiology, University Heart Centre, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Cardiovascular Research (DZHK), Partner Site Hamburg, Lübeck, Kiel, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<affiliation wicri:level="3"><nlm:affiliation>German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany, Department of Internal Medicine II - Cardiology, University of Ulm Medical Centre, Ulm, Germany, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany, Department of Internal Medicine II - Cardiology, University of Ulm Medical Centre, Ulm, Germany, Deutsches Herzzentrum München, Technische Universität München, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Epidemiology, and Health Services and Group Health Research Institute, Group Health Cooperative, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Epidemiology, and Health Services and Group Health Research Institute, Group Health Cooperative, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Haritunians, Talin" sort="Haritunians, Talin" uniqKey="Haritunians T" first="Talin" last="Haritunians">Talin Haritunians</name>
<affiliation wicri:level="2"><nlm:affiliation>Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Liu, Jingmin" sort="Liu, Jingmin" uniqKey="Liu J" first="Jingmin" last="Liu">Jingmin Liu</name>
<affiliation wicri:level="2"><nlm:affiliation>Fred Hutchinson Cancer Research Center, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<affiliation><nlm:affiliation>Institute for Molecular Medicine Finland (FIMM) and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute for Molecular Medicine Finland (FIMM) and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Stott, David J" sort="Stott, David J" uniqKey="Stott D" first="David J" last="Stott">David J. Stott</name>
<affiliation wicri:level="4"><nlm:affiliation>Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow</wicri:regionArea>
<orgName type="university">Université de Glasgow</orgName>
<placeName><settlement type="city">Glasgow</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<affiliation><nlm:affiliation>Department of Epidemiology.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Epidemiology.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H" last="Franco">Oscar H. Franco</name>
<affiliation><nlm:affiliation>Department of Epidemiology.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Epidemiology.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, Department of Public Health, Faculty of Medicine, Centre for Global Health, University of Split, Split, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, Department of Public Health, Faculty of Medicine, Centre for Global Health, University of Split, Split</wicri:regionArea>
<wicri:noRegion>Split</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name>
<affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Morange, Pierre Emmanuel" sort="Morange, Pierre Emmanuel" uniqKey="Morange P" first="Pierre-Emmanuel" last="Morange">Pierre-Emmanuel Morange</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratory of Haematology, La Timone Hospital, Marseille F-13385, France, INSERM, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385, France, Aix-Marseille University, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Laboratory of Haematology, La Timone Hospital, Marseille F-13385, France, INSERM, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385, France, Aix-Marseille University, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385</wicri:regionArea>
<wicri:noRegion>13385</wicri:noRegion>
<placeName><settlement type="city">Marseille</settlement>
<region type="région" nuts="2">Provence-Alpes-Côte d'Azur</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L R" last="Kardia">Sharon L R. Kardia</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name>
<affiliation wicri:level="2"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, Kings College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland, Folkhälsan Research Centre, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland, Folkhälsan Research Centre, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Unit of General Practice, Helsinki University Central Hospital, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hansen, Torben" sort="Hansen, Torben" uniqKey="Hansen T" first="Torben" last="Hansen">Torben Hansen</name>
<affiliation><nlm:affiliation>Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences and.</nlm:affiliation>
<wicri:noCountry code="subField">Faculty of Health and Medical Sciences and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Becker, Lewis C" sort="Becker, Lewis C" uniqKey="Becker L" first="Lewis C" last="Becker">Lewis C. Becker</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Scott, Rodney J" sort="Scott, Rodney J" uniqKey="Scott R" first="Rodney J" last="Scott">Rodney J. Scott</name>
<affiliation wicri:level="1"><nlm:affiliation>Information based Medicine Program, Hunter Medical Research Institute, New Lambton Heights, Australia, School of Biomedical Sciences and Pharmacy, University of Newcastle, New Lambton Heights, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Information based Medicine Program, Hunter Medical Research Institute, New Lambton Heights, Australia, School of Biomedical Sciences and Pharmacy, University of Newcastle, New Lambton Heights</wicri:regionArea>
<wicri:noRegion>New Lambton Heights</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mitchell, Paul" sort="Mitchell, Paul" uniqKey="Mitchell P" first="Paul" last="Mitchell">Paul Mitchell</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
</placeName>
<orgName type="university">Université de Sydney</orgName>
</affiliation>
</author>
<author><name sortKey="M Rz, Winfried" sort="M Rz, Winfried" uniqKey="M Rz W" first="Winfried" last="M Rz">Winfried M Rz</name>
<affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, Synlab Academy, Synlab Services LLC, Mannheim, Germany, Clinical Institute of Medical, Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, Synlab Academy, Synlab Services LLC, Mannheim, Germany, Clinical Institute of Medical, Chemical Laboratory Diagnostics, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wareham, Nick J" sort="Wareham, Nick J" uniqKey="Wareham N" first="Nick J" last="Wareham">Nick J. Wareham</name>
<affiliation><nlm:affiliation>MRC Epidemiology Unit, School of Clinical Medicine and.</nlm:affiliation>
<wicri:noCountry code="subField">School of Clinical Medicine and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name>
<affiliation><nlm:affiliation>Institute of Epidemiology II and DZHK (German Centre for Cardiovascular Research) and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Epidemiology II and DZHK (German Centre for Cardiovascular Research) and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Greinacher, Andreas" sort="Greinacher, Andreas" uniqKey="Greinacher A" first="Andreas" last="Greinacher">Andreas Greinacher</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wild, Philipp S" sort="Wild, Philipp S" uniqKey="Wild P" first="Philipp S" last="Wild">Philipp S. Wild</name>
<affiliation wicri:level="3"><nlm:affiliation>Center for Thrombosis and Hemostasis (CTH), Preventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany, German Center for Cardiovascular Research (DZHK), Partner Site RheinMain, Mainz, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center for Thrombosis and Hemostasis (CTH), Preventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany, German Center for Cardiovascular Research (DZHK), Partner Site RheinMain, Mainz</wicri:regionArea>
<placeName><region type="land" nuts="2">Rhénanie-Palatinat</region>
<settlement type="city">Mayence</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Cardiology, Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands, Interuniversity Cardiology Institute of The Netherlands, Utrecht, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands, Interuniversity Cardiology Institute of The Netherlands, Utrecht</wicri:regionArea>
<placeName><settlement type="city">Utrecht</settlement>
<region nuts="2" type="province">Utrecht (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</nlm:affiliation>
<wicri:noCountry code="subField">Institute of Genetics and Molecular Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cucca, Francesco" sort="Cucca, Francesco" uniqKey="Cucca F" first="Francesco" last="Cucca">Francesco Cucca</name>
<affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari</wicri:regionArea>
<wicri:noRegion>Cagliari</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tracy, Russell" sort="Tracy, Russell" uniqKey="Tracy R" first="Russell" last="Tracy">Russell Tracy</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Pathology and Laboratory Medicine, Center for Clinical and Translational Sciences, University of Vermont College of Medicine, Colchester, VT, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pathology and Laboratory Medicine, Center for Clinical and Translational Sciences, University of Vermont College of Medicine, Colchester, VT</wicri:regionArea>
<placeName><region type="state">Vermont</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name>
<affiliation wicri:level="4"><nlm:affiliation>Cardiovascular Medicine Department/Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cardiovascular Medicine Department/Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author><name sortKey="Reiner, Alex P" sort="Reiner, Alex P" uniqKey="Reiner A" first="Alex P" last="Reiner">Alex P. Reiner</name>
<affiliation wicri:level="4"><nlm:affiliation>Fred Hutchinson Cancer Research Center, Seattle, WA, USA, University of Washington, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Fred Hutchinson Cancer Research Center, Seattle, WA, USA, University of Washington, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
<settlement type="city">Seattle</settlement>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Folsom, Aaron R" sort="Folsom, Aaron R" uniqKey="Folsom A" first="Aaron R" last="Folsom">Aaron R. Folsom</name>
<affiliation><nlm:affiliation>Division of Epidemiology and Community Health and.</nlm:affiliation>
<wicri:noCountry code="no comma">Division of Epidemiology and Community Health and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA, Harvard Medical School, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA, Harvard Medical School, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="O Donnell, Christopher J" sort="O Donnell, Christopher J" uniqKey="O Donnell C" first="Christopher J" last="O'Donnell">Christopher J. O'Donnell</name>
<affiliation wicri:level="2"><nlm:affiliation>Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA, USA, National Heart, Lung and Blood Institute, Division of Intramural Research, Cardiology Division, Massachusetts General Hospital, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA, USA, National Heart, Lung and Blood Institute, Division of Intramural Research, Cardiology Division, Massachusetts General Hospital, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L" last="Smith">Nicholas L. Smith</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Epidemiology, University of Washington, Seattle, WA, USA, Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK, Department of Veterans Affairs, Office of Research and Development, Seattle Epidemiologic Research and Information Center, Seattle, WA, USA and.</nlm:affiliation>
<orgName type="university">Université de Washington</orgName>
<country>États-Unis</country>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name>
<affiliation wicri:level="4"><nlm:affiliation>Population Health Research Institute, St George's University of London, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Population Health Research Institute, St George's University of London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
<settlement type="city">Londres</settlement>
</placeName>
<orgName type="university">Université de Londres</orgName>
</affiliation>
</author>
<author><name sortKey="Dehghan, Abbas" sort="Dehghan, Abbas" uniqKey="Dehghan A" first="Abbas" last="Dehghan">Abbas Dehghan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, a.dehghan@erasmusmc.nl.</nlm:affiliation>
<country wicri:rule="url">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:26561523</idno>
<idno type="pmid">26561523</idno>
<idno type="doi">10.1093/hmg/ddv454</idno>
<idno type="wicri:Area/PubMed/Corpus">002410</idno>
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<idno type="wicri:Area/PubMed/Checkpoint">002364</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002364</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.</title>
<author><name sortKey="De Vries, Paul S" sort="De Vries, Paul S" uniqKey="De Vries P" first="Paul S" last="De Vries">Paul S. De Vries</name>
<affiliation><nlm:affiliation>Department of Epidemiology.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Epidemiology.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA, Harvard Medical School, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA, Harvard Medical School, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sabater Lleal, Maria" sort="Sabater Lleal, Maria" uniqKey="Sabater Lleal M" first="Maria" last="Sabater-Lleal">Maria Sabater-Lleal</name>
<affiliation><nlm:affiliation>Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit and.</nlm:affiliation>
<wicri:noCountry code="subField">Atherosclerosis Research Unit and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Chen, Ming Huei" sort="Chen, Ming Huei" uniqKey="Chen M" first="Ming-Huei" last="Chen">Ming-Huei Chen</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, Boston University School of Medicine, Boston, MA, USA, Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Boston University School of Medicine, Boston, MA, USA, Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Huffman, Jennifer E" sort="Huffman, Jennifer E" uniqKey="Huffman J" first="Jennifer E" last="Huffman">Jennifer E. Huffman</name>
<affiliation><nlm:affiliation>Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA, USA, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</nlm:affiliation>
<wicri:noCountry code="subField">Institute of Genetics and Molecular Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Steri, Maristella" sort="Steri, Maristella" uniqKey="Steri M" first="Maristella" last="Steri">Maristella Steri</name>
<affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari</wicri:regionArea>
<wicri:noRegion>Cagliari</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tang, Weihong" sort="Tang, Weihong" uniqKey="Tang W" first="Weihong" last="Tang">Weihong Tang</name>
<affiliation><nlm:affiliation>Division of Epidemiology and Community Health and.</nlm:affiliation>
<wicri:noCountry code="no comma">Division of Epidemiology and Community Health and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name>
<affiliation><nlm:affiliation>Institute for Community Medicine.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute for Community Medicine.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Marioni, Riccardo E" sort="Marioni, Riccardo E" uniqKey="Marioni R" first="Riccardo E" last="Marioni">Riccardo E. Marioni</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, Centre for Genomic and Experimental Medicine, Queensland Brain Institute, University of Queensland, Brisbane, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, Centre for Genomic and Experimental Medicine, Queensland Brain Institute, University of Queensland, Brisbane</wicri:regionArea>
<wicri:noRegion>Brisbane</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Grossmann, Vera" sort="Grossmann, Vera" uniqKey="Grossmann V" first="Vera" last="Grossmann">Vera Grossmann</name>
<affiliation><nlm:affiliation>Center for Thrombosis and Hemostasis (CTH).</nlm:affiliation>
<wicri:noCountry code="no comma">Center for Thrombosis and Hemostasis (CTH).</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Hottenga, Jouke J" sort="Hottenga, Jouke J" uniqKey="Hottenga J" first="Jouke J" last="Hottenga">Jouke J. Hottenga</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name>
<affiliation><nlm:affiliation>Department of Cardiology, Department of Gerontology and Geriatrics and.</nlm:affiliation>
<wicri:noCountry code="subField">Department of Gerontology and Geriatrics and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name>
<affiliation><nlm:affiliation>Institute of Genetic Epidemiology, Department of Medicine I, Ludwig-Maximilians-University Munich, Munich, Germany, DZHK (German Centre for Cardiovascular Research) and.</nlm:affiliation>
<wicri:noCountry code="subField">DZHK (German Centre for Cardiovascular Research) and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name>
<affiliation><nlm:affiliation>MRC Epidemiology Unit, School of Clinical Medicine and.</nlm:affiliation>
<wicri:noCountry code="subField">School of Clinical Medicine and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Brody, Jennifer A" sort="Brody, Jennifer A" uniqKey="Brody J" first="Jennifer A" last="Brody">Jennifer A. Brody</name>
<affiliation><nlm:affiliation>Department of Medicine.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Medicine.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kleber, Marcus E" sort="Kleber, Marcus E" uniqKey="Kleber M" first="Marcus E" last="Kleber">Marcus E. Kleber</name>
<affiliation wicri:level="3"><nlm:affiliation>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Mannheim</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Guo, Xiuqing" sort="Guo, Xiuqing" uniqKey="Guo X" first="Xiuqing" last="Guo">Xiuqing Guo</name>
<affiliation wicri:level="2"><nlm:affiliation>Institute for Translational Genomics and Population Sciences and Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor/UCLA Medical Center, Torrance, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Institute for Translational Genomics and Population Sciences and Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor/UCLA Medical Center, Torrance, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wang, Jie Jin" sort="Wang, Jie Jin" uniqKey="Wang J" first="Jie Jin" last="Wang">Jie Jin Wang</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
</placeName>
<orgName type="university">Université de Sydney</orgName>
</affiliation>
</author>
<author><name sortKey="Auer, Paul L" sort="Auer, Paul L" uniqKey="Auer P" first="Paul L" last="Auer">Paul L. Auer</name>
<affiliation wicri:level="2"><nlm:affiliation>Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI</wicri:regionArea>
<placeName><region type="state">Wisconsin</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Attia, John R" sort="Attia, John R" uniqKey="Attia J" first="John R" last="Attia">John R. Attia</name>
<affiliation><nlm:affiliation>Public Health Stream and School of Medicine and Public Health and.</nlm:affiliation>
<wicri:noCountry code="no comma">Public Health Stream and School of Medicine and Public Health and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Yanek, Lisa R" sort="Yanek, Lisa R" uniqKey="Yanek L" first="Lisa R" last="Yanek">Lisa R. Yanek</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ahluwalia, Tarunveer S" sort="Ahluwalia, Tarunveer S" uniqKey="Ahluwalia T" first="Tarunveer S" last="Ahluwalia">Tarunveer S. Ahluwalia</name>
<affiliation wicri:level="3"><nlm:affiliation>Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences and Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, The Danish Pediatric Asthma Center, Gentofte Hospital, The Capital Region, Copenhagen, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences and Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, The Danish Pediatric Asthma Center, Gentofte Hospital, The Capital Region, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lahti, Jari" sort="Lahti, Jari" uniqKey="Lahti J" first="Jari" last="Lahti">Jari Lahti</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute of Behavioural Sciences, Folkhälsan Research Centre, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute of Behavioural Sciences, Folkhälsan Research Centre, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Venturini, Cristina" sort="Venturini, Cristina" uniqKey="Venturini C" first="Cristina" last="Venturini">Cristina Venturini</name>
<affiliation wicri:level="3"><nlm:affiliation>Institute of Opthalmology, UCL, London, UK, Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Opthalmology, UCL, London, UK, Department of Twin Research and Genetic Epidemiology, Kings College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name>
<affiliation wicri:level="2"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bielak, Lawrence F" sort="Bielak, Lawrence F" uniqKey="Bielak L" first="Lawrence F" last="Bielak">Lawrence F. Bielak</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Joshi, Peter K" sort="Joshi, Peter K" uniqKey="Joshi P" first="Peter K" last="Joshi">Peter K. Joshi</name>
<affiliation><nlm:affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Rocanin Arjo, Ares" sort="Rocanin Arjo, Ares" uniqKey="Rocanin Arjo A" first="Ares" last="Rocanin-Arjo">Ares Rocanin-Arjo</name>
<affiliation wicri:level="3"><nlm:affiliation>Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1166, Paris F-75013, France, Sorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris F-75013, France, Institute for Cardiometabolism and Nutrition (ICAN), Paris F-75013, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1166, Paris F-75013, France, Sorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris F-75013, France, Institute for Cardiometabolism and Nutrition (ICAN), Paris F-75013</wicri:regionArea>
<placeName><region type="region" nuts="2">Île-de-France</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name>
<affiliation><nlm:affiliation>Department of Public Health, Faculty of Medicine.</nlm:affiliation>
<wicri:noCountry code="subField">Faculty of Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Navarro, Pau" sort="Navarro, Pau" uniqKey="Navarro P" first="Pau" last="Navarro">Pau Navarro</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</nlm:affiliation>
<wicri:noCountry code="subField">Institute of Genetics and Molecular Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Oldmeadow, Christopher" sort="Oldmeadow, Christopher" uniqKey="Oldmeadow C" first="Christopher" last="Oldmeadow">Christopher Oldmeadow</name>
<affiliation><nlm:affiliation>Public Health Stream and School of Medicine and Public Health and.</nlm:affiliation>
<wicri:noCountry code="no comma">Public Health Stream and School of Medicine and Public Health and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Riess, Helene" sort="Riess, Helene" uniqKey="Riess H" first="Helene" last="Riess">Helene Riess</name>
<affiliation><nlm:affiliation>Institute of Epidemiology II and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Epidemiology II and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Mazur, Johanna" sort="Mazur, Johanna" uniqKey="Mazur J" first="Johanna" last="Mazur">Johanna Mazur</name>
<affiliation><nlm:affiliation>Institute of Medical Biostatistics, Epidemiology and Informatics and.</nlm:affiliation>
<wicri:noCountry code="subField">Epidemiology and Informatics and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Basu, Saonli" sort="Basu, Saonli" uniqKey="Basu S" first="Saonli" last="Basu">Saonli Basu</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Biostatistics, University of Minnesota, Minneapolis, MN, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Biostatistics, University of Minnesota, Minneapolis, MN</wicri:regionArea>
<placeName><region type="state">Minnesota</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name>
<affiliation wicri:level="4"><nlm:affiliation>Cardiovascular Medicine Department/Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cardiovascular Medicine Department/Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author><name sortKey="Yang, Qiong" sort="Yang, Qiong" uniqKey="Yang Q" first="Qiong" last="Yang">Qiong Yang</name>
<affiliation wicri:level="2"><nlm:affiliation>Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA, USA, Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA, USA, Department of Biostatistics, Boston University School of Public Health, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ghanbari, Mohsen" sort="Ghanbari, Mohsen" uniqKey="Ghanbari M" first="Mohsen" last="Ghanbari">Mohsen Ghanbari</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Department of Epidemiology, Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad</wicri:regionArea>
<wicri:noRegion>Mashhad</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rumley, Ann" sort="Rumley, Ann" uniqKey="Rumley A" first="Ann" last="Rumley">Ann Rumley</name>
<affiliation><nlm:affiliation>Institute of Cardiovascular and Medical Sciences and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Cardiovascular and Medical Sciences and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fiorillo, Edoardo" sort="Fiorillo, Edoardo" uniqKey="Fiorillo E" first="Edoardo" last="Fiorillo">Edoardo Fiorillo</name>
<affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari</wicri:regionArea>
<wicri:noRegion>Cagliari</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Craen, Anton J M" sort="De Craen, Anton J M" uniqKey="De Craen A" first="Anton J M" last="De Craen">Anton J M. De Craen</name>
<affiliation><nlm:affiliation>Department of Gerontology and Geriatrics and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Gerontology and Geriatrics and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Grotevendt, Anne" sort="Grotevendt, Anne" uniqKey="Grotevendt A" first="Anne" last="Grotevendt">Anne Grotevendt</name>
<affiliation><nlm:affiliation>Institute of Clinical Chemistry and Laboratory Medicine.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Clinical Chemistry and Laboratory Medicine.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Scott, Robert" sort="Scott, Robert" uniqKey="Scott R" first="Robert" last="Scott">Robert Scott</name>
<affiliation><nlm:affiliation>MRC Epidemiology Unit, School of Clinical Medicine and.</nlm:affiliation>
<wicri:noCountry code="subField">School of Clinical Medicine and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Taylor, Kent D" sort="Taylor, Kent D" uniqKey="Taylor K" first="Kent D" last="Taylor">Kent D. Taylor</name>
<affiliation><nlm:affiliation>Institute for Translational Genomics and Population Sciences and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute for Translational Genomics and Population Sciences and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Delgado, Graciela E" sort="Delgado, Graciela E" uniqKey="Delgado G" first="Graciela E" last="Delgado">Graciela E. Delgado</name>
<affiliation wicri:level="3"><nlm:affiliation>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Mannheim</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yao, Jie" sort="Yao, Jie" uniqKey="Yao J" first="Jie" last="Yao">Jie Yao</name>
<affiliation><nlm:affiliation>Institute for Translational Genomics and Population Sciences and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute for Translational Genomics and Population Sciences and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kifley, Annette" sort="Kifley, Annette" uniqKey="Kifley A" first="Annette" last="Kifley">Annette Kifley</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
</placeName>
<orgName type="university">Université de Sydney</orgName>
</affiliation>
</author>
<author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name>
<affiliation wicri:level="2"><nlm:affiliation>Fred Hutchinson Cancer Research Center, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Qayyum, Rehan" sort="Qayyum, Rehan" uniqKey="Qayyum R" first="Rehan" last="Qayyum">Rehan Qayyum</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland, University College Dublin, UCD Conway Institute, Centre for Proteome Research, UCD, Belfield, Dublin, Ireland.</nlm:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland, University College Dublin, UCD Conway Institute, Centre for Proteome Research, UCD, Belfield, Dublin</wicri:regionArea>
<wicri:noRegion>Dublin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Berentzen, Tina L" sort="Berentzen, Tina L" uniqKey="Berentzen T" first="Tina L" last="Berentzen">Tina L. Berentzen</name>
<affiliation wicri:level="3"><nlm:affiliation>Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="R Ikkonen, Katri" sort="R Ikkonen, Katri" uniqKey="R Ikkonen K" first="Katri" last="R Ikkönen">Katri R Ikkönen</name>
<affiliation><nlm:affiliation>Institute of Behavioural Sciences.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Behavioural Sciences.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, Kings College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name>
<affiliation wicri:level="1"><nlm:affiliation>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence</wicri:regionArea>
<wicri:noRegion>Florence</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Peyser, Patricia A" sort="Peyser, Patricia A" uniqKey="Peyser P" first="Patricia A" last="Peyser">Patricia A. Peyser</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wild, Sarah" sort="Wild, Sarah" uniqKey="Wild S" first="Sarah" last="Wild">Sarah Wild</name>
<affiliation><nlm:affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Trégouët">David-Alexandre Trégouët</name>
<affiliation wicri:level="3"><nlm:affiliation>Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1166, Paris F-75013, France, Sorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris F-75013, France, Institute for Cardiometabolism and Nutrition (ICAN), Paris F-75013, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1166, Paris F-75013, France, Sorbonne Universités, Université Pierre et Marie Curie (UPMC Univ Paris 06), UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris F-75013, France, Institute for Cardiometabolism and Nutrition (ICAN), Paris F-75013</wicri:regionArea>
<placeName><region type="region" nuts="2">Île-de-France</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</nlm:affiliation>
<wicri:noCountry code="subField">Institute of Genetics and Molecular Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Marten, Jonathan" sort="Marten, Jonathan" uniqKey="Marten J" first="Jonathan" last="Marten">Jonathan Marten</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</nlm:affiliation>
<wicri:noCountry code="subField">Institute of Genetics and Molecular Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name>
<affiliation><nlm:affiliation>Department of Biology, School of Medicine and.</nlm:affiliation>
<wicri:noCountry code="subField">School of Medicine and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name>
<affiliation wicri:level="2"><nlm:affiliation>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit and Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit and Science for Life Laboratory, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tofler, Geoffrey" sort="Tofler, Geoffrey" uniqKey="Tofler G" first="Geoffrey" last="Tofler">Geoffrey Tofler</name>
<affiliation wicri:level="3"><nlm:affiliation>Royal North Shore Hospital, Sydney University, Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Royal North Shore Hospital, Sydney University, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Maat, Moniek P M" sort="De Maat, Moniek P M" uniqKey="De Maat M" first="Moniek P M" last="De Maat">Moniek P M. De Maat</name>
<affiliation><nlm:affiliation>Department of Hematology and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Hematology and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J C" last="De Geus">Eco J C. De Geus</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands, EMGO+ institute, VU University & VU Medical Center, Amsterdam.</nlm:affiliation>
<country>Pays-Bas</country>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
<wicri:orgArea>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands, EMGO+ institute, VU University & VU Medical Center</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Lowe, Gordon D" sort="Lowe, Gordon D" uniqKey="Lowe G" first="Gordon D" last="Lowe">Gordon D. Lowe</name>
<affiliation><nlm:affiliation>Institute of Cardiovascular and Medical Sciences and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Cardiovascular and Medical Sciences and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Zoledziewska, Magdalena" sort="Zoledziewska, Magdalena" uniqKey="Zoledziewska M" first="Magdalena" last="Zoledziewska">Magdalena Zoledziewska</name>
<affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari</wicri:regionArea>
<wicri:noRegion>Cagliari</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name>
<affiliation wicri:level="1"><nlm:affiliation>Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, Glasgow, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, Glasgow</wicri:regionArea>
<wicri:noRegion>Glasgow</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Binder, Harald" sort="Binder, Harald" uniqKey="Binder H" first="Harald" last="Binder">Harald Binder</name>
<affiliation><nlm:affiliation>Institute of Medical Biostatistics, Epidemiology and Informatics and.</nlm:affiliation>
<wicri:noCountry code="subField">Epidemiology and Informatics and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name>
<affiliation><nlm:affiliation>Interfaculty Institute for Genetics and Functional Genomics and.</nlm:affiliation>
<wicri:noCountry code="no comma">Interfaculty Institute for Genetics and Functional Genomics and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Waldenberger, Melanie" sort="Waldenberger, Melanie" uniqKey="Waldenberger M" first="Melanie" last="Waldenberger">Melanie Waldenberger</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute of Epidemiology II and Research Unit of Molecular Epidemiology, Helmholtz ZentrumMünchen - German Research Center for Environmental Health, Neuherberg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute of Epidemiology II and Research Unit of Molecular Epidemiology, Helmholtz ZentrumMünchen - German Research Center for Environmental Health, Neuherberg</wicri:regionArea>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
<wicri:noRegion>Neuherberg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name>
<affiliation wicri:level="4"><nlm:affiliation>Clinical Gerontology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Clinical Gerontology Unit, School of Clinical Medicine, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name>
<affiliation><nlm:affiliation>Department of Biostatistics.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Biostatistics.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Huang, Jie" sort="Huang, Jie" uniqKey="Huang J" first="Jie" last="Huang">Jie Huang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jenny, Nancy S" sort="Jenny, Nancy S" uniqKey="Jenny N" first="Nancy S" last="Jenny">Nancy S. Jenny</name>
<affiliation><nlm:affiliation>Department of Pathology and Laboratory Medicine and.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Pathology and Laboratory Medicine and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Holliday, Elizabeth G" sort="Holliday, Elizabeth G" uniqKey="Holliday E" first="Elizabeth G" last="Holliday">Elizabeth G. Holliday</name>
<affiliation><nlm:affiliation>Public Health Stream, Hunter Medical Research Institute, School of Medicine and Public Health and.</nlm:affiliation>
<wicri:noCountry code="subField">School of Medicine and Public Health and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Qi, Lihong" sort="Qi, Lihong" uniqKey="Qi L" first="Lihong" last="Qi">Lihong Qi</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Biostatistics, Department of Public Health Sciences, UC Davis, Davis, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Biostatistics, Department of Public Health Sciences, UC Davis, Davis, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcevoy, Mark G" sort="Mcevoy, Mark G" uniqKey="Mcevoy M" first="Mark G" last="Mcevoy">Mark G. Mcevoy</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Medicine and Public Health, University of Newcastle, Newcastle, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Medicine and Public Health, University of Newcastle, Newcastle</wicri:regionArea>
<wicri:noRegion>Newcastle</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Becker, Diane M" sort="Becker, Diane M" uniqKey="Becker D" first="Diane M" last="Becker">Diane M. Becker</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name>
<affiliation><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, Alzheimer Scotland Dementia Research Centre and.</nlm:affiliation>
<wicri:noCountry code="subField">Alzheimer Scotland Dementia Research Centre and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Sarin, Antti Pekka" sort="Sarin, Antti Pekka" uniqKey="Sarin A" first="Antti-Pekka" last="Sarin">Antti-Pekka Sarin</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Molecular Medicine Finland (FIMM) and Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Institute for Molecular Medicine Finland (FIMM) and Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, Kings College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hernandez, Dena G" sort="Hernandez, Dena G" uniqKey="Hernandez D" first="Dena G" last="Hernandez">Dena G. Hernandez</name>
<affiliation wicri:level="2"><nlm:affiliation>Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jhun, Min A" sort="Jhun, Min A" uniqKey="Jhun M" first="Min A" last="Jhun">Min A. Jhun</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name>
<affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name>
<affiliation><nlm:affiliation>Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit and.</nlm:affiliation>
<wicri:noCountry code="subField">Atherosclerosis Research Unit and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Social and Community Medicine, University of Bristol, Bristol, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>School of Social and Community Medicine, University of Bristol, Bristol</wicri:regionArea>
<wicri:noRegion>Bristol</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Slagboom, P Eline" sort="Slagboom, P Eline" uniqKey="Slagboom P" first="P Eline" last="Slagboom">P Eline Slagboom</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden</wicri:regionArea>
<placeName><settlement type="city">Leyde</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zeller, Tanja" sort="Zeller, Tanja" uniqKey="Zeller T" first="Tanja" last="Zeller">Tanja Zeller</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of General and Interventional Cardiology, University Heart Centre, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Cardiovascular Research (DZHK), Partner Site Hamburg, Lübeck, Kiel, Hamburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of General and Interventional Cardiology, University Heart Centre, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Cardiovascular Research (DZHK), Partner Site Hamburg, Lübeck, Kiel, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Koenig, Wolfgang" sort="Koenig, Wolfgang" uniqKey="Koenig W" first="Wolfgang" last="Koenig">Wolfgang Koenig</name>
<affiliation wicri:level="3"><nlm:affiliation>German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany, Department of Internal Medicine II - Cardiology, University of Ulm Medical Centre, Ulm, Germany, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany, Department of Internal Medicine II - Cardiology, University of Ulm Medical Centre, Ulm, Germany, Deutsches Herzzentrum München, Technische Universität München, Munich</wicri:regionArea>
<placeName><region type="land" nuts="1">Bavière</region>
<region type="district" nuts="2">District de Haute-Bavière</region>
<settlement type="city">Munich</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Epidemiology, and Health Services and Group Health Research Institute, Group Health Cooperative, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Epidemiology, and Health Services and Group Health Research Institute, Group Health Cooperative, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Haritunians, Talin" sort="Haritunians, Talin" uniqKey="Haritunians T" first="Talin" last="Haritunians">Talin Haritunians</name>
<affiliation wicri:level="2"><nlm:affiliation>Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Liu, Jingmin" sort="Liu, Jingmin" uniqKey="Liu J" first="Jingmin" last="Liu">Jingmin Liu</name>
<affiliation wicri:level="2"><nlm:affiliation>Fred Hutchinson Cancer Research Center, Seattle, WA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<affiliation><nlm:affiliation>Institute for Molecular Medicine Finland (FIMM) and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute for Molecular Medicine Finland (FIMM) and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam</wicri:regionArea>
<placeName><settlement type="city">Rotterdam</settlement>
<region nuts="2" type="province">Hollande-Méridionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Stott, David J" sort="Stott, David J" uniqKey="Stott D" first="David J" last="Stott">David J. Stott</name>
<affiliation wicri:level="4"><nlm:affiliation>Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow</wicri:regionArea>
<orgName type="university">Université de Glasgow</orgName>
<placeName><settlement type="city">Glasgow</settlement>
<region type="country">Écosse</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<affiliation><nlm:affiliation>Department of Epidemiology.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Epidemiology.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Franco, Oscar H" sort="Franco, Oscar H" uniqKey="Franco O" first="Oscar H" last="Franco">Oscar H. Franco</name>
<affiliation><nlm:affiliation>Department of Epidemiology.</nlm:affiliation>
<wicri:noCountry code="no comma">Department of Epidemiology.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, Department of Public Health, Faculty of Medicine, Centre for Global Health, University of Split, Split, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, Department of Public Health, Faculty of Medicine, Centre for Global Health, University of Split, Split</wicri:regionArea>
<wicri:noRegion>Split</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name>
<affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Morange, Pierre Emmanuel" sort="Morange, Pierre Emmanuel" uniqKey="Morange P" first="Pierre-Emmanuel" last="Morange">Pierre-Emmanuel Morange</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratory of Haematology, La Timone Hospital, Marseille F-13385, France, INSERM, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385, France, Aix-Marseille University, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Laboratory of Haematology, La Timone Hospital, Marseille F-13385, France, INSERM, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385, France, Aix-Marseille University, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385</wicri:regionArea>
<wicri:noRegion>13385</wicri:noRegion>
<placeName><settlement type="city">Marseille</settlement>
<region type="région" nuts="2">Provence-Alpes-Côte d'Azur</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</nlm:affiliation>
<wicri:noCountry code="subField">Usher Institute of Population Health Sciences and Informatics</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L R" last="Kardia">Sharon L R. Kardia</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name>
<affiliation wicri:level="2"><nlm:affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Translational Gerontology Branch, National Institute on Aging, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Twin Research and Genetic Epidemiology, Kings College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Eriksson, Johan G" sort="Eriksson, Johan G" uniqKey="Eriksson J" first="Johan G" last="Eriksson">Johan G. Eriksson</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland, Folkhälsan Research Centre, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland, Folkhälsan Research Centre, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Unit of General Practice, Helsinki University Central Hospital, Helsinki</wicri:regionArea>
<orgName type="university">Université d'Helsinki</orgName>
<placeName><settlement type="city">Helsinki</settlement>
<region type="région" nuts="2">Uusimaa</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hansen, Torben" sort="Hansen, Torben" uniqKey="Hansen T" first="Torben" last="Hansen">Torben Hansen</name>
<affiliation><nlm:affiliation>Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences and.</nlm:affiliation>
<wicri:noCountry code="subField">Faculty of Health and Medical Sciences and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh</wicri:regionArea>
<placeName><settlement type="city">Édimbourg</settlement>
<region type="country">Écosse</region>
<settlement type="city">Édimbourg</settlement>
</placeName>
<orgName type="university">Université d'Édimbourg</orgName>
</affiliation>
</author>
<author><name sortKey="Becker, Lewis C" sort="Becker, Lewis C" uniqKey="Becker L" first="Lewis C" last="Becker">Lewis C. Becker</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Scott, Rodney J" sort="Scott, Rodney J" uniqKey="Scott R" first="Rodney J" last="Scott">Rodney J. Scott</name>
<affiliation wicri:level="1"><nlm:affiliation>Information based Medicine Program, Hunter Medical Research Institute, New Lambton Heights, Australia, School of Biomedical Sciences and Pharmacy, University of Newcastle, New Lambton Heights, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Information based Medicine Program, Hunter Medical Research Institute, New Lambton Heights, Australia, School of Biomedical Sciences and Pharmacy, University of Newcastle, New Lambton Heights</wicri:regionArea>
<wicri:noRegion>New Lambton Heights</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mitchell, Paul" sort="Mitchell, Paul" uniqKey="Mitchell P" first="Paul" last="Mitchell">Paul Mitchell</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney</wicri:regionArea>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
<settlement type="city">Sydney</settlement>
</placeName>
<orgName type="university">Université de Sydney</orgName>
</affiliation>
</author>
<author><name sortKey="M Rz, Winfried" sort="M Rz, Winfried" uniqKey="M Rz W" first="Winfried" last="M Rz">Winfried M Rz</name>
<affiliation wicri:level="1"><nlm:affiliation>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, Synlab Academy, Synlab Services LLC, Mannheim, Germany, Clinical Institute of Medical, Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, Synlab Academy, Synlab Services LLC, Mannheim, Germany, Clinical Institute of Medical, Chemical Laboratory Diagnostics, Medical University of Graz, Graz</wicri:regionArea>
<wicri:noRegion>Graz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wareham, Nick J" sort="Wareham, Nick J" uniqKey="Wareham N" first="Nick J" last="Wareham">Nick J. Wareham</name>
<affiliation><nlm:affiliation>MRC Epidemiology Unit, School of Clinical Medicine and.</nlm:affiliation>
<wicri:noCountry code="subField">School of Clinical Medicine and</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name>
<affiliation><nlm:affiliation>Institute of Epidemiology II and DZHK (German Centre for Cardiovascular Research) and.</nlm:affiliation>
<wicri:noCountry code="no comma">Institute of Epidemiology II and DZHK (German Centre for Cardiovascular Research) and.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Greinacher, Andreas" sort="Greinacher, Andreas" uniqKey="Greinacher A" first="Andreas" last="Greinacher">Andreas Greinacher</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald</wicri:regionArea>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
<wicri:noRegion>Greifswald</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wild, Philipp S" sort="Wild, Philipp S" uniqKey="Wild P" first="Philipp S" last="Wild">Philipp S. Wild</name>
<affiliation wicri:level="3"><nlm:affiliation>Center for Thrombosis and Hemostasis (CTH), Preventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany, German Center for Cardiovascular Research (DZHK), Partner Site RheinMain, Mainz, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Center for Thrombosis and Hemostasis (CTH), Preventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany, German Center for Cardiovascular Research (DZHK), Partner Site RheinMain, Mainz</wicri:regionArea>
<placeName><region type="land" nuts="2">Rhénanie-Palatinat</region>
<settlement type="city">Mayence</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Cardiology, Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands, Interuniversity Cardiology Institute of The Netherlands, Utrecht, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Cardiology, Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands, Interuniversity Cardiology Institute of The Netherlands, Utrecht</wicri:regionArea>
<placeName><settlement type="city">Utrecht</settlement>
<region nuts="2" type="province">Utrecht (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name>
<affiliation><nlm:affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</nlm:affiliation>
<wicri:noCountry code="subField">Institute of Genetics and Molecular Medicine</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cucca, Francesco" sort="Cucca, Francesco" uniqKey="Cucca F" first="Francesco" last="Cucca">Francesco Cucca</name>
<affiliation wicri:level="1"><nlm:affiliation>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari</wicri:regionArea>
<wicri:noRegion>Cagliari</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tracy, Russell" sort="Tracy, Russell" uniqKey="Tracy R" first="Russell" last="Tracy">Russell Tracy</name>
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<author><name sortKey="Dehghan, Abbas" sort="Dehghan, Abbas" uniqKey="Dehghan A" first="Abbas" last="Dehghan">Abbas Dehghan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, a.dehghan@erasmusmc.nl.</nlm:affiliation>
<country wicri:rule="url">Pays-Bas</country>
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<series><title level="j">Human molecular genetics</title>
<idno type="eISSN">1460-2083</idno>
<imprint><date when="2016" type="published">2016</date>
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<term>Aged</term>
<term>Aged, 80 and over</term>
<term>European Continental Ancestry Group (genetics)</term>
<term>Female</term>
<term>Fibrinogen (analysis)</term>
<term>Fibrinogen (genetics)</term>
<term>Genetic Loci</term>
<term>Genome-Wide Association Study</term>
<term>Humans</term>
<term>INDEL Mutation</term>
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<term>Étude d'association pangénomique</term>
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<front><div type="abstract" xml:lang="en">Genome-wide association studies have previously identified 23 genetic loci associated with circulating fibrinogen concentration. These studies used HapMap imputation and did not examine the X-chromosome. 1000 Genomes imputation provides better coverage of uncommon variants, and includes indels. We conducted a genome-wide association analysis of 34 studies imputed to the 1000 Genomes Project reference panel and including ∼120 000 participants of European ancestry (95 806 participants with data on the X-chromosome). Approximately 10.7 million single-nucleotide polymorphisms and 1.2 million indels were examined. We identified 41 genome-wide significant fibrinogen loci; of which, 18 were newly identified. There were no genome-wide significant signals on the X-chromosome. The lead variants of five significant loci were indels. We further identified six additional independent signals, including three rare variants, at two previously characterized loci: FGB and IRF1. Together the 41 loci explain 3% of the variance in plasma fibrinogen concentration.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26561523</PMID>
<DateCreated><Year>2016</Year>
<Month>01</Month>
<Day>09</Day>
</DateCreated>
<DateCompleted><Year>2016</Year>
<Month>10</Month>
<Day>17</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>09</Month>
<Day>22</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1460-2083</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>25</Volume>
<Issue>2</Issue>
<PubDate><Year>2016</Year>
<Month>Jan</Month>
<Day>15</Day>
</PubDate>
</JournalIssue>
<Title>Human molecular genetics</Title>
<ISOAbbreviation>Hum. Mol. Genet.</ISOAbbreviation>
</Journal>
<ArticleTitle>A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.</ArticleTitle>
<Pagination><MedlinePgn>358-70</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1093/hmg/ddv454</ELocationID>
<Abstract><AbstractText>Genome-wide association studies have previously identified 23 genetic loci associated with circulating fibrinogen concentration. These studies used HapMap imputation and did not examine the X-chromosome. 1000 Genomes imputation provides better coverage of uncommon variants, and includes indels. We conducted a genome-wide association analysis of 34 studies imputed to the 1000 Genomes Project reference panel and including ∼120 000 participants of European ancestry (95 806 participants with data on the X-chromosome). Approximately 10.7 million single-nucleotide polymorphisms and 1.2 million indels were examined. We identified 41 genome-wide significant fibrinogen loci; of which, 18 were newly identified. There were no genome-wide significant signals on the X-chromosome. The lead variants of five significant loci were indels. We further identified six additional independent signals, including three rare variants, at two previously characterized loci: FGB and IRF1. Together the 41 loci explain 3% of the variance in plasma fibrinogen concentration.</AbstractText>
<CopyrightInformation>© The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.</CopyrightInformation>
</Abstract>
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<AffiliationInfo><Affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA, Harvard Medical School, Boston, MA, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Kooperberg</LastName>
<ForeName>Charles</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Fred Hutchinson Cancer Research Center, Seattle, WA, USA.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Qayyum</LastName>
<ForeName>Rehan</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Lopez</LastName>
<ForeName>Lorna M</ForeName>
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</Author>
<Author ValidYN="Y"><LastName>Berentzen</LastName>
<ForeName>Tina L</ForeName>
<Initials>TL</Initials>
<AffiliationInfo><Affiliation>Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Räikkönen</LastName>
<ForeName>Katri</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Institute of Behavioural Sciences.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Mangino</LastName>
<ForeName>Massimo</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</Affiliation>
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<Author ValidYN="Y"><LastName>Bandinelli</LastName>
<ForeName>Stefania</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Peyser</LastName>
<ForeName>Patricia A</ForeName>
<Initials>PA</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Wild</LastName>
<ForeName>Sarah</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Trégouët</LastName>
<ForeName>David-Alexandre</ForeName>
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</Author>
<Author ValidYN="Y"><LastName>Wright</LastName>
<ForeName>Alan F</ForeName>
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<AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Marten</LastName>
<ForeName>Jonathan</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</Affiliation>
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<Author ValidYN="Y"><LastName>Zemunik</LastName>
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<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Biology, School of Medicine and.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Morrison</LastName>
<ForeName>Alanna C</ForeName>
<Initials>AC</Initials>
<AffiliationInfo><Affiliation>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Sennblad</LastName>
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<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit and Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tofler</LastName>
<ForeName>Geoffrey</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Royal North Shore Hospital, Sydney University, Sydney, Australia.</Affiliation>
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<Author ValidYN="Y"><LastName>de Maat</LastName>
<ForeName>Moniek P M</ForeName>
<Initials>MP</Initials>
<AffiliationInfo><Affiliation>Department of Hematology and.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>de Geus</LastName>
<ForeName>Eco J C</ForeName>
<Initials>EJ</Initials>
<AffiliationInfo><Affiliation>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands, EMGO+ institute, VU University & VU Medical Center, Amsterdam.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Lowe</LastName>
<ForeName>Gordon D</ForeName>
<Initials>GD</Initials>
<AffiliationInfo><Affiliation>Institute of Cardiovascular and Medical Sciences and.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Zoledziewska</LastName>
<ForeName>Magdalena</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari, Italy.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Sattar</LastName>
<ForeName>Naveed</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, Glasgow, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Binder</LastName>
<ForeName>Harald</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Institute of Medical Biostatistics, Epidemiology and Informatics and.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Völker</LastName>
<ForeName>Uwe</ForeName>
<Initials>U</Initials>
<AffiliationInfo><Affiliation>Interfaculty Institute for Genetics and Functional Genomics and.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Waldenberger</LastName>
<ForeName>Melanie</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Institute of Epidemiology II and Research Unit of Molecular Epidemiology, Helmholtz ZentrumMünchen - German Research Center for Environmental Health, Neuherberg, Germany.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Khaw</LastName>
<ForeName>Kay-Tee</ForeName>
<Initials>KT</Initials>
<AffiliationInfo><Affiliation>Clinical Gerontology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Mcknight</LastName>
<ForeName>Barbara</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Biostatistics.</Affiliation>
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<Author ValidYN="Y"><LastName>Huang</LastName>
<ForeName>Jie</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Jenny</LastName>
<ForeName>Nancy S</ForeName>
<Initials>NS</Initials>
<AffiliationInfo><Affiliation>Department of Pathology and Laboratory Medicine and.</Affiliation>
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<Author ValidYN="Y"><LastName>Holliday</LastName>
<ForeName>Elizabeth G</ForeName>
<Initials>EG</Initials>
<AffiliationInfo><Affiliation>Public Health Stream, Hunter Medical Research Institute, School of Medicine and Public Health and.</Affiliation>
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<Author ValidYN="Y"><LastName>Qi</LastName>
<ForeName>Lihong</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Division of Biostatistics, Department of Public Health Sciences, UC Davis, Davis, CA, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Mcevoy</LastName>
<ForeName>Mark G</ForeName>
<Initials>MG</Initials>
<AffiliationInfo><Affiliation>School of Medicine and Public Health, University of Newcastle, Newcastle, Australia.</Affiliation>
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<Author ValidYN="Y"><LastName>Becker</LastName>
<ForeName>Diane M</ForeName>
<Initials>DM</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Starr</LastName>
<ForeName>John M</ForeName>
<Initials>JM</Initials>
<AffiliationInfo><Affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, Alzheimer Scotland Dementia Research Centre and.</Affiliation>
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<Author ValidYN="Y"><LastName>Sarin</LastName>
<ForeName>Antti-Pekka</ForeName>
<Initials>AP</Initials>
<AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland (FIMM) and Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Hysi</LastName>
<ForeName>Pirro G</ForeName>
<Initials>PG</Initials>
<AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</Affiliation>
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<Author ValidYN="Y"><LastName>Hernandez</LastName>
<ForeName>Dena G</ForeName>
<Initials>DG</Initials>
<AffiliationInfo><Affiliation>Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Jhun</LastName>
<ForeName>Min A</ForeName>
<Initials>MA</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Campbell</LastName>
<ForeName>Harry</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</Affiliation>
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<Author ValidYN="Y"><LastName>Hamsten</LastName>
<ForeName>Anders</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit and.</Affiliation>
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<Author ValidYN="Y"><LastName>Rivadeneira</LastName>
<ForeName>Fernando</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam, The Netherlands.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Mcardle</LastName>
<ForeName>Wendy L</ForeName>
<Initials>WL</Initials>
<AffiliationInfo><Affiliation>School of Social and Community Medicine, University of Bristol, Bristol, UK.</Affiliation>
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<Author ValidYN="Y"><LastName>Slagboom</LastName>
<ForeName>P Eline</ForeName>
<Initials>PE</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Zeller</LastName>
<ForeName>Tanja</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of General and Interventional Cardiology, University Heart Centre, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, German Center for Cardiovascular Research (DZHK), Partner Site Hamburg, Lübeck, Kiel, Hamburg, Germany.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Koenig</LastName>
<ForeName>Wolfgang</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany, Department of Internal Medicine II - Cardiology, University of Ulm Medical Centre, Ulm, Germany, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Psaty</LastName>
<ForeName>Bruce M</ForeName>
<Initials>BM</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Epidemiology, and Health Services and Group Health Research Institute, Group Health Cooperative, Seattle, WA, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Haritunians</LastName>
<ForeName>Talin</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Jingmin</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Fred Hutchinson Cancer Research Center, Seattle, WA, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Palotie</LastName>
<ForeName>Aarno</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Institute for Molecular Medicine Finland (FIMM) and.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Uitterlinden</LastName>
<ForeName>André G</ForeName>
<Initials>AG</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, Department of Internal Medicine, Erasmus MC, Wytemaweg 80, Rotterdam, The Netherlands.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Stott</LastName>
<ForeName>David J</ForeName>
<Initials>DJ</Initials>
<AffiliationInfo><Affiliation>Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Hofman</LastName>
<ForeName>Albert</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Franco</LastName>
<ForeName>Oscar H</ForeName>
<Initials>OH</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology.</Affiliation>
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<Author ValidYN="Y"><LastName>Polasek</LastName>
<ForeName>Ozren</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, Department of Public Health, Faculty of Medicine, Centre for Global Health, University of Split, Split, Croatia.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Rudan</LastName>
<ForeName>Igor</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Morange</LastName>
<ForeName>Pierre-Emmanuel</ForeName>
<Initials>PE</Initials>
<AffiliationInfo><Affiliation>Laboratory of Haematology, La Timone Hospital, Marseille F-13385, France, INSERM, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385, France, Aix-Marseille University, UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille F-13385, France.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Wilson</LastName>
<ForeName>James F</ForeName>
<Initials>JF</Initials>
<AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Kardia</LastName>
<ForeName>Sharon L R</ForeName>
<Initials>SL</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Ferrucci</LastName>
<ForeName>Luigi</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Spector</LastName>
<ForeName>Tim D</ForeName>
<Initials>TD</Initials>
<AffiliationInfo><Affiliation>Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Eriksson</LastName>
<ForeName>Johan G</ForeName>
<Initials>JG</Initials>
<AffiliationInfo><Affiliation>Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland, Folkhälsan Research Centre, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Hansen</LastName>
<ForeName>Torben</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences and.</Affiliation>
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<Author ValidYN="Y"><LastName>Deary</LastName>
<ForeName>Ian J</ForeName>
<Initials>IJ</Initials>
<AffiliationInfo><Affiliation>Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, University of Edinburgh, Edinburgh, UK.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Becker</LastName>
<ForeName>Lewis C</ForeName>
<Initials>LC</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Scott</LastName>
<ForeName>Rodney J</ForeName>
<Initials>RJ</Initials>
<AffiliationInfo><Affiliation>Information based Medicine Program, Hunter Medical Research Institute, New Lambton Heights, Australia, School of Biomedical Sciences and Pharmacy, University of Newcastle, New Lambton Heights, Australia.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Mitchell</LastName>
<ForeName>Paul</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Ophthalmology, Centre for Vision Research, Westmead Millennium Institute for Medical Research, University of Sydney, Sydney, Australia.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>März</LastName>
<ForeName>Winfried</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, Synlab Academy, Synlab Services LLC, Mannheim, Germany, Clinical Institute of Medical, Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Wareham</LastName>
<ForeName>Nick J</ForeName>
<Initials>NJ</Initials>
<AffiliationInfo><Affiliation>MRC Epidemiology Unit, School of Clinical Medicine and.</Affiliation>
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<Author ValidYN="Y"><LastName>Peters</LastName>
<ForeName>Annette</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Institute of Epidemiology II and DZHK (German Centre for Cardiovascular Research) and.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Greinacher</LastName>
<ForeName>Andreas</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Wild</LastName>
<ForeName>Philipp S</ForeName>
<Initials>PS</Initials>
<AffiliationInfo><Affiliation>Center for Thrombosis and Hemostasis (CTH), Preventive Cardiology and Preventive Medicine, Department of Medicine 2, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany, German Center for Cardiovascular Research (DZHK), Partner Site RheinMain, Mainz, Germany.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Jukema</LastName>
<ForeName>J Wouter</ForeName>
<Initials>JW</Initials>
<AffiliationInfo><Affiliation>Department of Cardiology, Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands, Interuniversity Cardiology Institute of The Netherlands, Utrecht, The Netherlands.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Boomsma</LastName>
<ForeName>Dorret I</ForeName>
<Initials>DI</Initials>
<AffiliationInfo><Affiliation>Department of Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, The Netherlands.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Hayward</LastName>
<ForeName>Caroline</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine.</Affiliation>
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<Author ValidYN="Y"><LastName>Cucca</LastName>
<ForeName>Francesco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionaledelle Ricerche, Monserrato, Cagliari, Italy.</Affiliation>
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<Author ValidYN="Y"><LastName>Tracy</LastName>
<ForeName>Russell</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Pathology and Laboratory Medicine, Center for Clinical and Translational Sciences, University of Vermont College of Medicine, Colchester, VT, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Watkins</LastName>
<ForeName>Hugh</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Cardiovascular Medicine Department/Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Reiner</LastName>
<ForeName>Alex P</ForeName>
<Initials>AP</Initials>
<AffiliationInfo><Affiliation>Fred Hutchinson Cancer Research Center, Seattle, WA, USA, University of Washington, Seattle, WA, USA.</Affiliation>
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<Author ValidYN="Y"><LastName>Folsom</LastName>
<ForeName>Aaron R</ForeName>
<Initials>AR</Initials>
<AffiliationInfo><Affiliation>Division of Epidemiology and Community Health and.</Affiliation>
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<Author ValidYN="Y"><LastName>Ridker</LastName>
<ForeName>Paul M</ForeName>
<Initials>PM</Initials>
<AffiliationInfo><Affiliation>Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA, Harvard Medical School, Boston, MA, USA.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>O'Donnell</LastName>
<ForeName>Christopher J</ForeName>
<Initials>CJ</Initials>
<AffiliationInfo><Affiliation>Framingham Heart Study, Population Sciences Branch, Division of Intramural Research National Heart Lung and Blood Institute, National Institutes of Health, Framingham, MA, USA, National Heart, Lung and Blood Institute, Division of Intramural Research, Cardiology Division, Massachusetts General Hospital, Boston, MA, USA.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Smith</LastName>
<ForeName>Nicholas L</ForeName>
<Initials>NL</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, University of Washington, Seattle, WA, USA, Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK, Department of Veterans Affairs, Office of Research and Development, Seattle Epidemiologic Research and Information Center, Seattle, WA, USA and.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Strachan</LastName>
<ForeName>David P</ForeName>
<Initials>DP</Initials>
<AffiliationInfo><Affiliation>Population Health Research Institute, St George's University of London, London, UK.</Affiliation>
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</Author>
<Author ValidYN="Y"><LastName>Dehghan</LastName>
<ForeName>Abbas</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, a.dehghan@erasmusmc.nl.</Affiliation>
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<li>Uusimaa</li>
<li>Vermont</li>
<li>Washington (État)</li>
<li>Wisconsin</li>
<li>Écosse</li>
<li>Île-de-France</li>
</region>
<settlement><li>Amsterdam</li>
<li>Cambridge</li>
<li>Copenhague</li>
<li>Glasgow</li>
<li>Hambourg</li>
<li>Helsinki</li>
<li>Leyde</li>
<li>Londres</li>
<li>Mannheim</li>
<li>Marseille</li>
<li>Mayence</li>
<li>Munich</li>
<li>Oxford</li>
<li>Rotterdam</li>
<li>Seattle</li>
<li>Stockholm</li>
<li>Sydney</li>
<li>Utrecht</li>
<li>Édimbourg</li>
</settlement>
<orgName><li>Université d'Helsinki</li>
<li>Université d'Oxford</li>
<li>Université d'Édimbourg</li>
<li>Université de Cambridge</li>
<li>Université de Glasgow</li>
<li>Université de Londres</li>
<li>Université de Sydney</li>
<li>Université de Washington</li>
</orgName>
</list>
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<name sortKey="Binder, Harald" sort="Binder, Harald" uniqKey="Binder H" first="Harald" last="Binder">Harald Binder</name>
<name sortKey="Brody, Jennifer A" sort="Brody, Jennifer A" uniqKey="Brody J" first="Jennifer A" last="Brody">Jennifer A. Brody</name>
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<name sortKey="De Craen, Anton J M" sort="De Craen, Anton J M" uniqKey="De Craen A" first="Anton J M" last="De Craen">Anton J M. De Craen</name>
<name sortKey="De Maat, Moniek P M" sort="De Maat, Moniek P M" uniqKey="De Maat M" first="Moniek P M" last="De Maat">Moniek P M. De Maat</name>
<name sortKey="De Vries, Paul S" sort="De Vries, Paul S" uniqKey="De Vries P" first="Paul S" last="De Vries">Paul S. De Vries</name>
<name sortKey="Folsom, Aaron R" sort="Folsom, Aaron R" uniqKey="Folsom A" first="Aaron R" last="Folsom">Aaron R. Folsom</name>
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<name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name>
<name sortKey="Holliday, Elizabeth G" sort="Holliday, Elizabeth G" uniqKey="Holliday E" first="Elizabeth G" last="Holliday">Elizabeth G. Holliday</name>
<name sortKey="Huffman, Jennifer E" sort="Huffman, Jennifer E" uniqKey="Huffman J" first="Jennifer E" last="Huffman">Jennifer E. Huffman</name>
<name sortKey="Jenny, Nancy S" sort="Jenny, Nancy S" uniqKey="Jenny N" first="Nancy S" last="Jenny">Nancy S. Jenny</name>
<name sortKey="Joshi, Peter K" sort="Joshi, Peter K" uniqKey="Joshi P" first="Peter K" last="Joshi">Peter K. Joshi</name>
<name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name>
<name sortKey="Lowe, Gordon D" sort="Lowe, Gordon D" uniqKey="Lowe G" first="Gordon D" last="Lowe">Gordon D. Lowe</name>
<name sortKey="Marten, Jonathan" sort="Marten, Jonathan" uniqKey="Marten J" first="Jonathan" last="Marten">Jonathan Marten</name>
<name sortKey="Mazur, Johanna" sort="Mazur, Johanna" uniqKey="Mazur J" first="Johanna" last="Mazur">Johanna Mazur</name>
<name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name>
<name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name>
<name sortKey="Navarro, Pau" sort="Navarro, Pau" uniqKey="Navarro P" first="Pau" last="Navarro">Pau Navarro</name>
<name sortKey="Oldmeadow, Christopher" sort="Oldmeadow, Christopher" uniqKey="Oldmeadow C" first="Christopher" last="Oldmeadow">Christopher Oldmeadow</name>
<name sortKey="Palotie, Aarno" sort="Palotie, Aarno" uniqKey="Palotie A" first="Aarno" last="Palotie">Aarno Palotie</name>
<name sortKey="Peters, Annette" sort="Peters, Annette" uniqKey="Peters A" first="Annette" last="Peters">Annette Peters</name>
<name sortKey="R Ikkonen, Katri" sort="R Ikkonen, Katri" uniqKey="R Ikkonen K" first="Katri" last="R Ikkönen">Katri R Ikkönen</name>
<name sortKey="Riess, Helene" sort="Riess, Helene" uniqKey="Riess H" first="Helene" last="Riess">Helene Riess</name>
<name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name>
<name sortKey="Rumley, Ann" sort="Rumley, Ann" uniqKey="Rumley A" first="Ann" last="Rumley">Ann Rumley</name>
<name sortKey="Sabater Lleal, Maria" sort="Sabater Lleal, Maria" uniqKey="Sabater Lleal M" first="Maria" last="Sabater-Lleal">Maria Sabater-Lleal</name>
<name sortKey="Scott, Robert" sort="Scott, Robert" uniqKey="Scott R" first="Robert" last="Scott">Robert Scott</name>
<name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name>
<name sortKey="Tang, Weihong" sort="Tang, Weihong" uniqKey="Tang W" first="Weihong" last="Tang">Weihong Tang</name>
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<name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name>
<name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name>
<name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name>
<name sortKey="Wareham, Nick J" sort="Wareham, Nick J" uniqKey="Wareham N" first="Nick J" last="Wareham">Nick J. Wareham</name>
<name sortKey="Wild, Sarah" sort="Wild, Sarah" uniqKey="Wild S" first="Sarah" last="Wild">Sarah Wild</name>
<name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name>
<name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name>
<name sortKey="Yao, Jie" sort="Yao, Jie" uniqKey="Yao J" first="Jie" last="Yao">Jie Yao</name>
<name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name>
<name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name>
</noCountry>
<country name="États-Unis"><region name="Massachusetts"><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name>
</region>
<name sortKey="Auer, Paul L" sort="Auer, Paul L" uniqKey="Auer P" first="Paul L" last="Auer">Paul L. Auer</name>
<name sortKey="Basu, Saonli" sort="Basu, Saonli" uniqKey="Basu S" first="Saonli" last="Basu">Saonli Basu</name>
<name sortKey="Becker, Diane M" sort="Becker, Diane M" uniqKey="Becker D" first="Diane M" last="Becker">Diane M. Becker</name>
<name sortKey="Becker, Lewis C" sort="Becker, Lewis C" uniqKey="Becker L" first="Lewis C" last="Becker">Lewis C. Becker</name>
<name sortKey="Bielak, Lawrence F" sort="Bielak, Lawrence F" uniqKey="Bielak L" first="Lawrence F" last="Bielak">Lawrence F. Bielak</name>
<name sortKey="Chen, Ming Huei" sort="Chen, Ming Huei" uniqKey="Chen M" first="Ming-Huei" last="Chen">Ming-Huei Chen</name>
<name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name>
<name sortKey="Guo, Xiuqing" sort="Guo, Xiuqing" uniqKey="Guo X" first="Xiuqing" last="Guo">Xiuqing Guo</name>
<name sortKey="Haritunians, Talin" sort="Haritunians, Talin" uniqKey="Haritunians T" first="Talin" last="Haritunians">Talin Haritunians</name>
<name sortKey="Hernandez, Dena G" sort="Hernandez, Dena G" uniqKey="Hernandez D" first="Dena G" last="Hernandez">Dena G. Hernandez</name>
<name sortKey="Jhun, Min A" sort="Jhun, Min A" uniqKey="Jhun M" first="Min A" last="Jhun">Min A. Jhun</name>
<name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L R" last="Kardia">Sharon L R. Kardia</name>
<name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name>
<name sortKey="Liu, Jingmin" sort="Liu, Jingmin" uniqKey="Liu J" first="Jingmin" last="Liu">Jingmin Liu</name>
<name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name>
<name sortKey="O Donnell, Christopher J" sort="O Donnell, Christopher J" uniqKey="O Donnell C" first="Christopher J" last="O'Donnell">Christopher J. O'Donnell</name>
<name sortKey="Peyser, Patricia A" sort="Peyser, Patricia A" uniqKey="Peyser P" first="Patricia A" last="Peyser">Patricia A. Peyser</name>
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<name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name>
<name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name>
<name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L" last="Smith">Nicholas L. Smith</name>
<name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name>
<name sortKey="Tracy, Russell" sort="Tracy, Russell" uniqKey="Tracy R" first="Russell" last="Tracy">Russell Tracy</name>
<name sortKey="Yanek, Lisa R" sort="Yanek, Lisa R" uniqKey="Yanek L" first="Lisa R" last="Yanek">Lisa R. Yanek</name>
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<country name="Italie"><noRegion><name sortKey="Steri, Maristella" sort="Steri, Maristella" uniqKey="Steri M" first="Maristella" last="Steri">Maristella Steri</name>
</noRegion>
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<name sortKey="Fiorillo, Edoardo" sort="Fiorillo, Edoardo" uniqKey="Fiorillo E" first="Edoardo" last="Fiorillo">Edoardo Fiorillo</name>
<name sortKey="Zoledziewska, Magdalena" sort="Zoledziewska, Magdalena" uniqKey="Zoledziewska M" first="Magdalena" last="Zoledziewska">Magdalena Zoledziewska</name>
</country>
<country name="Australie"><noRegion><name sortKey="Marioni, Riccardo E" sort="Marioni, Riccardo E" uniqKey="Marioni R" first="Riccardo E" last="Marioni">Riccardo E. Marioni</name>
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<name sortKey="Mitchell, Paul" sort="Mitchell, Paul" uniqKey="Mitchell P" first="Paul" last="Mitchell">Paul Mitchell</name>
<name sortKey="Scott, Rodney J" sort="Scott, Rodney J" uniqKey="Scott R" first="Rodney J" last="Scott">Rodney J. Scott</name>
<name sortKey="Tofler, Geoffrey" sort="Tofler, Geoffrey" uniqKey="Tofler G" first="Geoffrey" last="Tofler">Geoffrey Tofler</name>
<name sortKey="Wang, Jie Jin" sort="Wang, Jie Jin" uniqKey="Wang J" first="Jie Jin" last="Wang">Jie Jin Wang</name>
</country>
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</region>
<name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name>
<name sortKey="De Geus, Eco J C" sort="De Geus, Eco J C" uniqKey="De Geus E" first="Eco J C" last="De Geus">Eco J C. De Geus</name>
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<name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name>
<name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name>
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<name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G" last="Uitterlinden">André G. Uitterlinden</name>
<name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name>
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</region>
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</country>
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</region>
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</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Venturini, Cristina" sort="Venturini, Cristina" uniqKey="Venturini C" first="Cristina" last="Venturini">Cristina Venturini</name>
</region>
<name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name>
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<name sortKey="Huang, Jie" sort="Huang, Jie" uniqKey="Huang J" first="Jie" last="Huang">Jie Huang</name>
<name sortKey="Hysi, Pirro G" sort="Hysi, Pirro G" uniqKey="Hysi P" first="Pirro G" last="Hysi">Pirro G. Hysi</name>
<name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name>
<name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name>
<name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name>
<name sortKey="Sattar, Naveed" sort="Sattar, Naveed" uniqKey="Sattar N" first="Naveed" last="Sattar">Naveed Sattar</name>
<name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name>
<name sortKey="Stott, David J" sort="Stott, David J" uniqKey="Stott D" first="David J" last="Stott">David J. Stott</name>
<name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name>
<name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name>
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<country name="France"><region name="Île-de-France"><name sortKey="Rocanin Arjo, Ares" sort="Rocanin Arjo, Ares" uniqKey="Rocanin Arjo A" first="Ares" last="Rocanin-Arjo">Ares Rocanin-Arjo</name>
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<name sortKey="Morange, Pierre Emmanuel" sort="Morange, Pierre Emmanuel" uniqKey="Morange P" first="Pierre-Emmanuel" last="Morange">Pierre-Emmanuel Morange</name>
<name sortKey="Tregouet, David Alexandre" sort="Tregouet, David Alexandre" uniqKey="Tregouet D" first="David-Alexandre" last="Trégouët">David-Alexandre Trégouët</name>
</country>
<country name="Iran"><noRegion><name sortKey="Ghanbari, Mohsen" sort="Ghanbari, Mohsen" uniqKey="Ghanbari M" first="Mohsen" last="Ghanbari">Mohsen Ghanbari</name>
</noRegion>
</country>
<country name="Irlande (pays)"><noRegion><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name>
</noRegion>
</country>
<country name="Suède"><region name="Svealand"><name sortKey="Sennblad, Bengt" sort="Sennblad, Bengt" uniqKey="Sennblad B" first="Bengt" last="Sennblad">Bengt Sennblad</name>
</region>
</country>
<country name="Croatie"><noRegion><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name>
</noRegion>
</country>
<country name="Autriche"><noRegion><name sortKey="M Rz, Winfried" sort="M Rz, Winfried" uniqKey="M Rz W" first="Winfried" last="M Rz">Winfried M Rz</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
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