Longer-term oral antiplatelet use in stable post-myocardial infarction patients: Insights from the long Term rIsk, clinical manaGement and healthcare Resource utilization of stable coronary artery dISease (TIGRIS) observational study.
Identifieur interne : 000868 ( PubMed/Checkpoint ); précédent : 000867; suivant : 000869Longer-term oral antiplatelet use in stable post-myocardial infarction patients: Insights from the long Term rIsk, clinical manaGement and healthcare Resource utilization of stable coronary artery dISease (TIGRIS) observational study.
Auteurs : Shaun G. Goodman [Canada] ; Jose C. Nicolau [Brésil] ; Gema Requena [Royaume-Uni] ; Andrew Maguire [Royaume-Uni] ; Stefan Blankenberg [Allemagne] ; Ji Yan Chen [République populaire de Chine] ; Christopher B. Granger [États-Unis] ; Richard Grieve [Royaume-Uni] ; Stuart J. Pocock [Royaume-Uni] ; Tabassome Simon [France] ; Satoshi Yasuda [Japon] ; Ana Maria Vega [Espagne] ; David Brieger [Australie]Source :
- International journal of cardiology [ 1874-1754 ] ; 2017.
Abstract
To describe contemporary patient characteristics and treatment patterns, including antithrombotic management, of post-myocardial infarction (MI) stable coronary artery disease (CAD) patients at high atherothrombotic risk from different geographical regions.
DOI: 10.1016/j.ijcard.2017.02.062
PubMed: 28268087
Affiliations:
- Allemagne, Australie, Brésil, Canada, Espagne, France, Japon, Royaume-Uni, République populaire de Chine, États-Unis
- Angleterre, Communauté de Madrid, Grand Londres, Guangdong, Hambourg, Nouvelle-Galles du Sud, Ontario, État de São Paulo, Île-de-France
- Hambourg, Jiangmen, Londres, Madrid, Paris, Sydney, São Paulo, Toronto
- Université de Sydney, Université de Toronto
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Electronic address: goodmans@smh.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Nicolau, Jose C" sort="Nicolau, Jose C" uniqKey="Nicolau J" first="Jose C" last="Nicolau">Jose C. Nicolau</name><affiliation wicri:level="3"><nlm:affiliation>Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Heart Institute (InCor), University of São Paulo Medical School, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Requena, Gema" sort="Requena, Gema" uniqKey="Requena G" first="Gema" last="Requena">Gema Requena</name><affiliation wicri:level="3"><nlm:affiliation>Oxon Epidemiology (UK), London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxon Epidemiology (UK), London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Maguire, Andrew" sort="Maguire, Andrew" uniqKey="Maguire A" first="Andrew" last="Maguire">Andrew Maguire</name><affiliation wicri:level="3"><nlm:affiliation>Oxon Epidemiology (UK), London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxon Epidemiology (UK), London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Blankenberg, Stefan" sort="Blankenberg, Stefan" uniqKey="Blankenberg S" first="Stefan" last="Blankenberg">Stefan Blankenberg</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cardiology, University Heart Center Eppendorf, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cardiology, University Heart Center Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Chen, Ji Yan" sort="Chen, Ji Yan" uniqKey="Chen J" first="Ji Yan" last="Chen">Ji Yan Chen</name><affiliation wicri:level="3"><nlm:affiliation>Guangdong General Hospital, Provincial Key Laboratory of Coronary Disease, Guangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Guangdong General Hospital, Provincial Key Laboratory of Coronary Disease, Guangzhou</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Granger, Christopher B" sort="Granger, Christopher B" uniqKey="Granger C" first="Christopher B" last="Granger">Christopher B. Granger</name><affiliation wicri:level="1"><nlm:affiliation>Duke Clinical Research Institute, Duke University Medical Center, Durham, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Duke Clinical Research Institute, Duke University Medical Center, Durham</wicri:regionArea><wicri:noRegion>Durham</wicri:noRegion></affiliation></author><author><name sortKey="Grieve, Richard" sort="Grieve, Richard" uniqKey="Grieve R" first="Richard" last="Grieve">Richard Grieve</name><affiliation wicri:level="3"><nlm:affiliation>London School of Hygiene and Tropical Medicine, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Pocock, Stuart J" sort="Pocock, Stuart J" uniqKey="Pocock S" first="Stuart J" last="Pocock">Stuart J. 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Goodman</name><affiliation wicri:level="4"><nlm:affiliation>Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Canada. Electronic address: goodmans@smh.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Nicolau, Jose C" sort="Nicolau, Jose C" uniqKey="Nicolau J" first="Jose C" last="Nicolau">Jose C. Nicolau</name><affiliation wicri:level="3"><nlm:affiliation>Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Heart Institute (InCor), University of São Paulo Medical School, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Requena, Gema" sort="Requena, Gema" uniqKey="Requena G" first="Gema" last="Requena">Gema Requena</name><affiliation wicri:level="3"><nlm:affiliation>Oxon Epidemiology (UK), London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxon Epidemiology (UK), London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Maguire, Andrew" sort="Maguire, Andrew" uniqKey="Maguire A" first="Andrew" last="Maguire">Andrew Maguire</name><affiliation wicri:level="3"><nlm:affiliation>Oxon Epidemiology (UK), London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxon Epidemiology (UK), London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Blankenberg, Stefan" sort="Blankenberg, Stefan" uniqKey="Blankenberg S" first="Stefan" last="Blankenberg">Stefan Blankenberg</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cardiology, University Heart Center Eppendorf, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cardiology, University Heart Center Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Chen, Ji Yan" sort="Chen, Ji Yan" uniqKey="Chen J" first="Ji Yan" last="Chen">Ji Yan Chen</name><affiliation wicri:level="3"><nlm:affiliation>Guangdong General Hospital, Provincial Key Laboratory of Coronary Disease, Guangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Guangdong General Hospital, Provincial Key Laboratory of Coronary Disease, Guangzhou</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Granger, Christopher B" sort="Granger, Christopher B" uniqKey="Granger C" first="Christopher B" last="Granger">Christopher B. Granger</name><affiliation wicri:level="1"><nlm:affiliation>Duke Clinical Research Institute, Duke University Medical Center, Durham, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Duke Clinical Research Institute, Duke University Medical Center, Durham</wicri:regionArea><wicri:noRegion>Durham</wicri:noRegion></affiliation></author><author><name sortKey="Grieve, Richard" sort="Grieve, Richard" uniqKey="Grieve R" first="Richard" last="Grieve">Richard Grieve</name><affiliation wicri:level="3"><nlm:affiliation>London School of Hygiene and Tropical Medicine, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Pocock, Stuart J" sort="Pocock, Stuart J" uniqKey="Pocock S" first="Stuart J" last="Pocock">Stuart J. Pocock</name><affiliation wicri:level="3"><nlm:affiliation>London School of Hygiene and Tropical Medicine, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Simon, Tabassome" sort="Simon, Tabassome" uniqKey="Simon T" first="Tabassome" last="Simon">Tabassome Simon</name><affiliation wicri:level="3"><nlm:affiliation>Assistance Publique-Hopitaux de Paris (APHP), UPMC-Paris 06 University, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique-Hopitaux de Paris (APHP), UPMC-Paris 06 University, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Yasuda, Satoshi" sort="Yasuda, Satoshi" uniqKey="Yasuda S" first="Satoshi" last="Yasuda">Satoshi Yasuda</name><affiliation wicri:level="1"><nlm:affiliation>National Cerebral and Cardiovascular Center, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>National Cerebral and Cardiovascular Center, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Vega, Ana Maria" sort="Vega, Ana Maria" uniqKey="Vega A" first="Ana Maria" last="Vega">Ana Maria Vega</name><affiliation wicri:level="3"><nlm:affiliation>Medical Evidence and Observational Research, Global Medical Affairs, AstraZeneca, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Medical Evidence and Observational Research, Global Medical Affairs, AstraZeneca, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Brieger, David" sort="Brieger, David" uniqKey="Brieger D" first="David" last="Brieger">David Brieger</name><affiliation wicri:level="4"><nlm:affiliation>Concord Hospital and University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Concord Hospital and University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author></analytic><series><title level="j">International journal of cardiology</title><idno type="eISSN">1874-1754</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To describe contemporary patient characteristics and treatment patterns, including antithrombotic management, of post-myocardial infarction (MI) stable coronary artery disease (CAD) patients at high atherothrombotic risk from different geographical regions.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28268087</PMID><DateCreated><Year>2017</Year><Month>03</Month><Day>07</Day></DateCreated><DateRevised><Year>2017</Year><Month>04</Month><Day>14</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1874-1754</ISSN><JournalIssue CitedMedium="Internet"><Volume>236</Volume><PubDate><Year>2017</Year><Month>Jun</Month><Day>01</Day></PubDate></JournalIssue><Title>International journal of cardiology</Title><ISOAbbreviation>Int. J. Cardiol.</ISOAbbreviation></Journal><ArticleTitle>Longer-term oral antiplatelet use in stable post-myocardial infarction patients: Insights from the long Term rIsk, clinical manaGement and healthcare Resource utilization of stable coronary artery dISease (TIGRIS) observational study.</ArticleTitle><Pagination><MedlinePgn>54-60</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0167-5273(16)34202-4</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ijcard.2017.02.062</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To describe contemporary patient characteristics and treatment patterns, including antithrombotic management, of post-myocardial infarction (MI) stable coronary artery disease (CAD) patients at high atherothrombotic risk from different geographical regions.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Patients ≥50years with prior MI 1-3years ago and ≥1 risk factor (age ≥65years, diabetes, 2nd prior MI >1yr ago, multivessel CAD, creatinine clearance 15-<60ml/min) were enrolled by 369 physicians (96% cardiologists) in 25 countries (2013-14) in the prospective TIGRIS study (NCT01866904).</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">9225 patients were enrolled (median 1.8years) post-MI: 52% with prior ST-elevation MI, median age 67years, 24% women, 67% Caucasian, 55% had ≥2 additional qualifying risk factors, 14% current smokers, 67% overweight/obese, 34% with blood pressure ≥140/90mmHg. 81% underwent percutaneous coronary intervention (PCI; 66% with drug-eluting stents) for the index MI. 75% of patients had been discharged on dual antiplatelet therapy (DAPT; acetylsalicylic acid [ASA]+ADP receptor inhibitor [ADPri]), mainly clopidogrel (75%). 63% had discontinued antiplatelet treatment (60% ADPri) around 1year, most commonly by physician recommendation (90%). At enrolment, 97% were taking an antithrombotic drug, most commonly ASA (88%), with 27% on DAPT (median duration 1.6years); continued DAPT >1year was highest (39%) in Asia-Pacific and lowest (12%) in Europe.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Despite guideline recommendations, 1 in 4 post-MI patients did not receive DAPT for ~1year. In contrast to guideline recommendations supporting newer ADPris, clopidogrel was mainly prescribed. Prior to recent RCT data supporting DAPT >1year post-MI/PCI, >1 in 4 patients have continued on DAPT, though with substantial international variability.</AbstractText><CopyrightInformation>Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Goodman</LastName><ForeName>Shaun G</ForeName><Initials>SG</Initials><AffiliationInfo><Affiliation>Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Canada. Electronic address: goodmans@smh.ca.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nicolau</LastName><ForeName>Jose C</ForeName><Initials>JC</Initials><AffiliationInfo><Affiliation>Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Requena</LastName><ForeName>Gema</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Oxon Epidemiology (UK), London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maguire</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Oxon Epidemiology (UK), London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Blankenberg</LastName><ForeName>Stefan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Division of Cardiology, University Heart Center Eppendorf, Hamburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Ji Yan</ForeName><Initials>JY</Initials><AffiliationInfo><Affiliation>Guangdong General Hospital, Provincial Key Laboratory of Coronary Disease, Guangzhou, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Granger</LastName><ForeName>Christopher B</ForeName><Initials>CB</Initials><AffiliationInfo><Affiliation>Duke Clinical Research Institute, Duke University Medical Center, Durham, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grieve</LastName><ForeName>Richard</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>London School of Hygiene and Tropical Medicine, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pocock</LastName><ForeName>Stuart J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>London School of Hygiene and Tropical Medicine, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Simon</LastName><ForeName>Tabassome</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Assistance Publique-Hopitaux de Paris (APHP), UPMC-Paris 06 University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yasuda</LastName><ForeName>Satoshi</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>National Cerebral and Cardiovascular Center, Osaka, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vega</LastName><ForeName>Ana Maria</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Medical Evidence and Observational Research, Global Medical Affairs, AstraZeneca, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brieger</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Concord Hospital and University of Sydney, Sydney, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>TIGRIS Study Investigators</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>02</Month><Day>21</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Int J Cardiol</MedlineTA><NlmUniqueID>8200291</NlmUniqueID><ISSNLinking>0167-5273</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Antiplatelet therapy</Keyword><Keyword MajorTopicYN="N">Myocardial infarction</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>12</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>02</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>02</Month><Day>19</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>3</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>3</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>3</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28268087</ArticleId><ArticleId IdType="pii">S0167-5273(16)34202-4</ArticleId><ArticleId IdType="doi">10.1016/j.ijcard.2017.02.062</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Brésil</li><li>Canada</li><li>Espagne</li><li>France</li><li>Japon</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Communauté de Madrid</li><li>Grand Londres</li><li>Guangdong</li><li>Hambourg</li><li>Nouvelle-Galles du Sud</li><li>Ontario</li><li>État de São Paulo</li><li>Île-de-France</li></region><settlement><li>Hambourg</li><li>Jiangmen</li><li>Londres</li><li>Madrid</li><li>Paris</li><li>Sydney</li><li>São Paulo</li><li>Toronto</li></settlement><orgName><li>Université de Sydney</li><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><region name="Ontario"><name sortKey="Goodman, Shaun G" sort="Goodman, Shaun G" uniqKey="Goodman S" first="Shaun G" last="Goodman">Shaun G. Goodman</name></region></country><country name="Brésil"><region name="État de São Paulo"><name sortKey="Nicolau, Jose C" sort="Nicolau, Jose C" uniqKey="Nicolau J" first="Jose C" last="Nicolau">Jose C. Nicolau</name></region></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Requena, Gema" sort="Requena, Gema" uniqKey="Requena G" first="Gema" last="Requena">Gema Requena</name></region><name sortKey="Grieve, Richard" sort="Grieve, Richard" uniqKey="Grieve R" first="Richard" last="Grieve">Richard Grieve</name><name sortKey="Maguire, Andrew" sort="Maguire, Andrew" uniqKey="Maguire A" first="Andrew" last="Maguire">Andrew Maguire</name><name sortKey="Pocock, Stuart J" sort="Pocock, Stuart J" uniqKey="Pocock S" first="Stuart J" last="Pocock">Stuart J. Pocock</name></country><country name="Allemagne"><region name="Hambourg"><name sortKey="Blankenberg, Stefan" sort="Blankenberg, Stefan" uniqKey="Blankenberg S" first="Stefan" last="Blankenberg">Stefan Blankenberg</name></region></country><country name="République populaire de Chine"><region name="Guangdong"><name sortKey="Chen, Ji Yan" sort="Chen, Ji Yan" uniqKey="Chen J" first="Ji Yan" last="Chen">Ji Yan Chen</name></region></country><country name="États-Unis"><noRegion><name sortKey="Granger, Christopher B" sort="Granger, Christopher B" uniqKey="Granger C" first="Christopher B" last="Granger">Christopher B. Granger</name></noRegion></country><country name="France"><region name="Île-de-France"><name sortKey="Simon, Tabassome" sort="Simon, Tabassome" uniqKey="Simon T" first="Tabassome" last="Simon">Tabassome Simon</name></region></country><country name="Japon"><noRegion><name sortKey="Yasuda, Satoshi" sort="Yasuda, Satoshi" uniqKey="Yasuda S" first="Satoshi" last="Yasuda">Satoshi Yasuda</name></noRegion></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Vega, Ana Maria" sort="Vega, Ana Maria" uniqKey="Vega A" first="Ana Maria" last="Vega">Ana Maria Vega</name></region></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Brieger, David" sort="Brieger, David" uniqKey="Brieger D" first="David" last="Brieger">David Brieger</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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