AustralieFrV1, PubMed, Checkpoint, bibRecord, 000497

RNA-sequence analysis of gene expression from honeybees (Apis mellifera) infected with Nosema ceranae.

Identifieur interne : 000497 ( PubMed/Checkpoint ); précédent : 000496; suivant : 000498

RNA-sequence analysis of gene expression from honeybees (Apis mellifera) infected with Nosema ceranae.

Auteurs : Bouabid Badaoui [Italie] ; André Fougeroux [France] ; Fabien Petit [France] ; Anna Anselmo [Italie] ; Chiara Gorni [Italie] ; Marco Cucurachi [Italie] ; Antonella Cersini [Italie] ; Anna Granato [Italie] ; Giusy Cardeti [Italie] ; Giovanni Formato [Italie] ; Franco Mutinelli [Italie] ; Elisabetta Giuffra [Italie] ; John L. Williams [Australie] ; Sara Botti [Italie]

Source :

PloS one [ 1932-6203 ] ; 2017.

RBID : pubmed:28350872

Descripteurs français

English descriptors

KwdEn :
- Animals, Bees (genetics), Bees (microbiology), Energy Metabolism (genetics), Gene Expression Profiling (methods), Genes, Insect (genetics), Host-Pathogen Interactions, Insect Proteins (genetics), Nosema (physiology), Principal Component Analysis, Promoter Regions, Genetic (genetics), Protein Isoforms (genetics), Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, RNA (methods), Signal Transduction (genetics), Spores, Fungal (physiology), Time Factors, Transcription Initiation Site.
MESH :
- chemical , genetics : Insect Proteins, Protein Isoforms.
- genetics : Bees, Energy Metabolism, Genes, Insect, Promoter Regions, Genetic, Signal Transduction.
- methods : Gene Expression Profiling, Sequence Analysis, RNA.
- microbiology : Bees.
- physiology : Nosema, Spores, Fungal.
- Animals, Host-Pathogen Interactions, Principal Component Analysis, Reverse Transcriptase Polymerase Chain Reaction, Time Factors, Transcription Initiation Site.

Abstract

Honeybees (Apis mellifera) are constantly subjected to many biotic stressors including parasites. This study examined honeybees infected with Nosema ceranae (N. ceranae). N. ceranae infection increases the bees energy requirements and may contribute to their decreased survival. RNA-seq was used to investigate gene expression at days 5, 10 and 15 Post Infection (P.I) with N. ceranae. The expression levels of genes, isoforms, alternative transcription start sites (TSS) and differential promoter usage revealed a complex pattern of transcriptional and post-transcriptional gene regulation suggesting that bees use a range of tactics to cope with the stress of N. ceranae infection. N. ceranae infection may cause reduced immune function in the bees by: (i)disturbing the host amino acids metabolism (ii) down-regulating expression of antimicrobial peptides (iii) down-regulation of cuticle coatings and (iv) down-regulation of odorant binding proteins.

DOI: 10.1371/journal.pone.0173438
PubMed: 28350872

Affiliations:

Australie, France, Italie
Centre-Val de Loire, Latium, Région Centre
Rome, Tours

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Le document en format XML

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<term>Bees (genetics)</term>
<term>Bees (microbiology)</term>
<term>Energy Metabolism (genetics)</term>
<term>Gene Expression Profiling (methods)</term>
<term>Genes, Insect (genetics)</term>
<term>Host-Pathogen Interactions</term>
<term>Insect Proteins (genetics)</term>
<term>Nosema (physiology)</term>
<term>Principal Component Analysis</term>
<term>Promoter Regions, Genetic (genetics)</term>
<term>Protein Isoforms (genetics)</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
<term>Sequence Analysis, RNA (methods)</term>
<term>Signal Transduction (genetics)</term>
<term>Spores, Fungal (physiology)</term>
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<term>Transcription Initiation Site</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Abeilles (génétique)</term>
<term>Abeilles (microbiologie)</term>
<term>Analyse de profil d'expression de gènes ()</term>
<term>Analyse de séquence d'ARN ()</term>
<term>Analyse en composantes principales</term>
<term>Animaux</term>
<term>Facteurs temps</term>
<term>Gènes d'insecte (génétique)</term>
<term>Interactions hôte-pathogène</term>
<term>Isoformes de protéines (génétique)</term>
<term>Métabolisme énergétique (génétique)</term>
<term>Nosema (physiologie)</term>
<term>Protéines d'insecte (génétique)</term>
<term>RT-PCR</term>
<term>Régions promotrices (génétique) (génétique)</term>
<term>Site d'initiation de la transcription</term>
<term>Spores fongiques (physiologie)</term>
<term>Transduction du signal (génétique)</term>
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<term>Protein Isoforms</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Bees</term>
<term>Energy Metabolism</term>
<term>Genes, Insect</term>
<term>Promoter Regions, Genetic</term>
<term>Signal Transduction</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Abeilles</term>
<term>Gènes d'insecte</term>
<term>Isoformes de protéines</term>
<term>Métabolisme énergétique</term>
<term>Protéines d'insecte</term>
<term>Régions promotrices (génétique)</term>
<term>Transduction du signal</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Gene Expression Profiling</term>
<term>Sequence Analysis, RNA</term>
</keywords>
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</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Bees</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Nosema</term>
<term>Spores fongiques</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Nosema</term>
<term>Spores, Fungal</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Host-Pathogen Interactions</term>
<term>Principal Component Analysis</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
<term>Time Factors</term>
<term>Transcription Initiation Site</term>
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<term>Analyse de séquence d'ARN</term>
<term>Analyse en composantes principales</term>
<term>Animaux</term>
<term>Facteurs temps</term>
<term>Interactions hôte-pathogène</term>
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<front><div type="abstract" xml:lang="en">Honeybees (Apis mellifera) are constantly subjected to many biotic stressors including parasites. This study examined honeybees infected with Nosema ceranae (N. ceranae). N. ceranae infection increases the bees energy requirements and may contribute to their decreased survival. RNA-seq was used to investigate gene expression at days 5, 10 and 15 Post Infection (P.I) with N. ceranae. The expression levels of genes, isoforms, alternative transcription start sites (TSS) and differential promoter usage revealed a complex pattern of transcriptional and post-transcriptional gene regulation suggesting that bees use a range of tactics to cope with the stress of N. ceranae infection. N. ceranae infection may cause reduced immune function in the bees by: (i)disturbing the host amino acids metabolism (ii) down-regulating expression of antimicrobial peptides (iii) down-regulation of cuticle coatings and (iv) down-regulation of odorant binding proteins.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28350872</PMID>
<DateCreated><Year>2017</Year>
<Month>03</Month>
<Day>28</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>08</Month>
<Day>28</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>08</Month>
<Day>28</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>12</Volume>
<Issue>3</Issue>
<PubDate><Year>2017</Year>
</PubDate>
</JournalIssue>
<Title>PloS one</Title>
<ISOAbbreviation>PLoS ONE</ISOAbbreviation>
</Journal>
<ArticleTitle>RNA-sequence analysis of gene expression from honeybees (Apis mellifera) infected with Nosema ceranae.</ArticleTitle>
<Pagination><MedlinePgn>e0173438</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0173438</ELocationID>
<Abstract><AbstractText>Honeybees (Apis mellifera) are constantly subjected to many biotic stressors including parasites. This study examined honeybees infected with Nosema ceranae (N. ceranae). N. ceranae infection increases the bees energy requirements and may contribute to their decreased survival. RNA-seq was used to investigate gene expression at days 5, 10 and 15 Post Infection (P.I) with N. ceranae. The expression levels of genes, isoforms, alternative transcription start sites (TSS) and differential promoter usage revealed a complex pattern of transcriptional and post-transcriptional gene regulation suggesting that bees use a range of tactics to cope with the stress of N. ceranae infection. N. ceranae infection may cause reduced immune function in the bees by: (i)disturbing the host amino acids metabolism (ii) down-regulating expression of antimicrobial peptides (iii) down-regulation of cuticle coatings and (iv) down-regulation of odorant binding proteins.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Badaoui</LastName>
<ForeName>Bouabid</ForeName>
<Initials>B</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0001-6808-1765</Identifier>
<AffiliationInfo><Affiliation>Parco Tecnologico Padano - CERSA, Integrative Biology Group, Lodi, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fougeroux</LastName>
<ForeName>André</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Syngenta, Guyancourt, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Petit</LastName>
<ForeName>Fabien</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>RNAGRO, TOURS, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Anselmo</LastName>
<ForeName>Anna</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Parco Tecnologico Padano - CERSA, Integrative Biology Group, Lodi, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gorni</LastName>
<ForeName>Chiara</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Parco Tecnologico Padano - CERSA, Integrative Biology Group, Lodi, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cucurachi</LastName>
<ForeName>Marco</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Parco Tecnologico Padano - CERSA, Integrative Biology Group, Lodi, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cersini</LastName>
<ForeName>Antonella</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Istituto Zooprofilattico Sperimentale del Lazio e della Toscana, Roma, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Granato</LastName>
<ForeName>Anna</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padua, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cardeti</LastName>
<ForeName>Giusy</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Istituto Zooprofilattico Sperimentale del Lazio e della Toscana, Roma, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Formato</LastName>
<ForeName>Giovanni</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Istituto Zooprofilattico Sperimentale del Lazio e della Toscana, Roma, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mutinelli</LastName>
<ForeName>Franco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, Padua, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Giuffra</LastName>
<ForeName>Elisabetta</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Parco Tecnologico Padano - CERSA, Integrative Biology Group, Lodi, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Williams</LastName>
<ForeName>John L</ForeName>
<Initials>JL</Initials>
<AffiliationInfo><Affiliation>Davies Research Centre, University of Adelaide, Roseworthy, South Australia, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Botti</LastName>
<ForeName>Sara</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Parco Tecnologico Padano - CERSA, Integrative Biology Group, Lodi, Italy.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2017</Year>
<Month>03</Month>
<Day>28</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>PLoS One</MedlineTA>
<NlmUniqueID>101285081</NlmUniqueID>
<ISSNLinking>1932-6203</ISSNLinking>
</MedlineJournalInfo>
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<NameOfSubstance UI="D019476">Insect Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D020033">Protein Isoforms</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001516" MajorTopicYN="N">Bees</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004734" MajorTopicYN="N">Energy Metabolism</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020869" MajorTopicYN="N">Gene Expression Profiling</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017344" MajorTopicYN="N">Genes, Insect</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D054884" MajorTopicYN="N">Host-Pathogen Interactions</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019476" MajorTopicYN="N">Insect Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016818" MajorTopicYN="N">Nosema</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D025341" MajorTopicYN="N">Principal Component Analysis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011401" MajorTopicYN="N">Promoter Regions, Genetic</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020033" MajorTopicYN="N">Protein Isoforms</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020133" MajorTopicYN="N">Reverse Transcriptase Polymerase Chain Reaction</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017423" MajorTopicYN="N">Sequence Analysis, RNA</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015398" MajorTopicYN="N">Signal Transduction</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013172" MajorTopicYN="N">Spores, Fungal</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D024363" MajorTopicYN="N">Transcription Initiation Site</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year>
<Month>09</Month>
<Day>02</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2017</Year>
<Month>02</Month>
<Day>22</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2017</Year>
<Month>3</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>3</Month>
<Day>30</Day>
<Hour>6</Hour>
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<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>8</Month>
<Day>29</Day>
<Hour>6</Hour>
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<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">28350872</ArticleId>
<ArticleId IdType="doi">10.1371/journal.pone.0173438</ArticleId>
<ArticleId IdType="pii">PONE-D-15-32809</ArticleId>
<ArticleId IdType="pmc">PMC5370102</ArticleId>
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<affiliations><list><country><li>Australie</li>
<li>France</li>
<li>Italie</li>
</country>
<region><li>Centre-Val de Loire</li>
<li>Latium</li>
<li>Région Centre</li>
</region>
<settlement><li>Rome</li>
<li>Tours</li>
</settlement>
</list>
<tree><country name="Italie"><noRegion><name sortKey="Badaoui, Bouabid" sort="Badaoui, Bouabid" uniqKey="Badaoui B" first="Bouabid" last="Badaoui">Bouabid Badaoui</name>
</noRegion>
<name sortKey="Anselmo, Anna" sort="Anselmo, Anna" uniqKey="Anselmo A" first="Anna" last="Anselmo">Anna Anselmo</name>
<name sortKey="Botti, Sara" sort="Botti, Sara" uniqKey="Botti S" first="Sara" last="Botti">Sara Botti</name>
<name sortKey="Cardeti, Giusy" sort="Cardeti, Giusy" uniqKey="Cardeti G" first="Giusy" last="Cardeti">Giusy Cardeti</name>
<name sortKey="Cersini, Antonella" sort="Cersini, Antonella" uniqKey="Cersini A" first="Antonella" last="Cersini">Antonella Cersini</name>
<name sortKey="Cucurachi, Marco" sort="Cucurachi, Marco" uniqKey="Cucurachi M" first="Marco" last="Cucurachi">Marco Cucurachi</name>
<name sortKey="Formato, Giovanni" sort="Formato, Giovanni" uniqKey="Formato G" first="Giovanni" last="Formato">Giovanni Formato</name>
<name sortKey="Giuffra, Elisabetta" sort="Giuffra, Elisabetta" uniqKey="Giuffra E" first="Elisabetta" last="Giuffra">Elisabetta Giuffra</name>
<name sortKey="Gorni, Chiara" sort="Gorni, Chiara" uniqKey="Gorni C" first="Chiara" last="Gorni">Chiara Gorni</name>
<name sortKey="Granato, Anna" sort="Granato, Anna" uniqKey="Granato A" first="Anna" last="Granato">Anna Granato</name>
<name sortKey="Mutinelli, Franco" sort="Mutinelli, Franco" uniqKey="Mutinelli F" first="Franco" last="Mutinelli">Franco Mutinelli</name>
</country>
<country name="France"><noRegion><name sortKey="Fougeroux, Andre" sort="Fougeroux, Andre" uniqKey="Fougeroux A" first="André" last="Fougeroux">André Fougeroux</name>
</noRegion>
<name sortKey="Petit, Fabien" sort="Petit, Fabien" uniqKey="Petit F" first="Fabien" last="Petit">Fabien Petit</name>
</country>
<country name="Australie"><noRegion><name sortKey="Williams, John L" sort="Williams, John L" uniqKey="Williams J" first="John L" last="Williams">John L. Williams</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000497 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000497 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:28350872
   |texte=   RNA-sequence analysis of gene expression from honeybees (Apis mellifera) infected with Nosema ceranae.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:28350872" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur les relations entre la France et l'Australie

RNA-sequence analysis of gene expression from honeybees (Apis mellifera) infected with Nosema ceranae.

RNA-sequence analysis of gene expression from honeybees (Apis mellifera) infected with Nosema ceranae.

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Descripteurs français

English descriptors

Abstract

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Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki