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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia</title><author><name sortKey="Grever, Michael R" sort="Grever, Michael R" uniqKey="Grever M" first="Michael R." last="Grever">Michael R. Grever</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Abdel Wahab, Omar" sort="Abdel Wahab, Omar" uniqKey="Abdel Wahab O" first="Omar" last="Abdel-Wahab">Omar Abdel-Wahab</name><affiliation><nlm:aff id="aff2">Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;</nlm:aff></affiliation></author><author><name sortKey="Andritsos, Leslie A" sort="Andritsos, Leslie A" uniqKey="Andritsos L" first="Leslie A." last="Andritsos">Leslie A. Andritsos</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Banerji, Versha" sort="Banerji, Versha" uniqKey="Banerji V" first="Versha" last="Banerji">Versha Banerji</name><affiliation><nlm:aff id="aff3">Section of Hematology/Oncology, University of Manitoba, Winnipeg, MB, Canada;</nlm:aff></affiliation></author><author><name sortKey="Barrientos, Jacqueline" sort="Barrientos, Jacqueline" uniqKey="Barrientos J" first="Jacqueline" last="Barrientos">Jacqueline Barrientos</name><affiliation><nlm:aff id="aff4">Department of Medicine, Hofstra North Shore-Long Island Jewish School of Medicine, Hofstra University, Hempstead, NY;</nlm:aff></affiliation></author><author><name sortKey="Blachly, James S" sort="Blachly, James S" uniqKey="Blachly J" first="James S." last="Blachly">James S. Blachly</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Call, Timothy G" sort="Call, Timothy G" uniqKey="Call T" first="Timothy G." last="Call">Timothy G. Call</name><affiliation><nlm:aff id="aff5">Division of Hematology, Mayo Clinic, Rochester, MN;</nlm:aff></affiliation></author><author><name sortKey="Catovsky, Daniel" sort="Catovsky, Daniel" uniqKey="Catovsky D" first="Daniel" last="Catovsky">Daniel Catovsky</name><affiliation><nlm:aff id="aff6">Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom;</nlm:aff></affiliation></author><author><name sortKey="Dearden, Claire" sort="Dearden, Claire" uniqKey="Dearden C" first="Claire" last="Dearden">Claire Dearden</name><affiliation><nlm:aff id="aff7">Department of Haemato-Oncology, Royal Marsden Biomedical Research Centre, London, United Kingdom;</nlm:aff></affiliation></author><author><name sortKey="Demeter, Judit" sort="Demeter, Judit" uniqKey="Demeter J" first="Judit" last="Demeter">Judit Demeter</name><affiliation><nlm:aff id="aff8">First Department of Internal Medicine, Semmelweis University, Budapest, Hungary;</nlm:aff></affiliation></author><author><name sortKey="Else, Monica" sort="Else, Monica" uniqKey="Else M" first="Monica" last="Else">Monica Else</name><affiliation><nlm:aff id="aff6">Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom;</nlm:aff></affiliation></author><author><name sortKey="Forconi, Francesco" sort="Forconi, Francesco" uniqKey="Forconi F" first="Francesco" last="Forconi">Francesco Forconi</name><affiliation><nlm:aff id="aff9">Haematology Department, University Hospital Trust and Cancer Sciences Unit, Cancer Research UK and National Institute for Health Research Experimental Cancer Medicine Centres, Faculty of Medicine, University of Southampton, Southampton, United Kingdom;</nlm:aff></affiliation></author><author><name sortKey="Gozzetti, Alessandro" sort="Gozzetti, Alessandro" uniqKey="Gozzetti A" first="Alessandro" last="Gozzetti">Alessandro Gozzetti</name><affiliation><nlm:aff id="aff10">Hematology, Azienda Ospedaliera Universitaria Senese, Siena, Italy;</nlm:aff></affiliation></author><author><name sortKey="Ho, Anthony D" sort="Ho, Anthony D" uniqKey="Ho A" first="Anthony D." last="Ho">Anthony D. Ho</name><affiliation><nlm:aff id="aff11">Department of Medicine V, University of Heidelberg, Heidelberg, Germany;</nlm:aff></affiliation></author><author><name sortKey="Johnston, James B" sort="Johnston, James B" uniqKey="Johnston J" first="James B." last="Johnston">James B. Johnston</name><affiliation><nlm:aff id="aff3">Section of Hematology/Oncology, University of Manitoba, Winnipeg, MB, Canada;</nlm:aff></affiliation></author><author><name sortKey="Jones, Jeffrey" sort="Jones, Jeffrey" uniqKey="Jones J" first="Jeffrey" last="Jones">Jeffrey Jones</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Juliusson, Gunnar" sort="Juliusson, Gunnar" uniqKey="Juliusson G" first="Gunnar" last="Juliusson">Gunnar Juliusson</name><affiliation><nlm:aff id="aff12">Department of Hematology, Skåne University Hospital and Stem Cell Center, Lund University, Lund, Sweden;</nlm:aff></affiliation></author><author><name sortKey="Kraut, Eric" sort="Kraut, Eric" uniqKey="Kraut E" first="Eric" last="Kraut">Eric Kraut</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Kreitman, Robert J" sort="Kreitman, Robert J" uniqKey="Kreitman R" first="Robert J." last="Kreitman">Robert J. Kreitman</name><affiliation><nlm:aff id="aff13">Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD;</nlm:aff></affiliation></author><author><name sortKey="Larratt, Loree" sort="Larratt, Loree" uniqKey="Larratt L" first="Loree" last="Larratt">Loree Larratt</name><affiliation><nlm:aff id="aff14">Department of Medicine, University of Alberta, Edmonton, AB, Canada;</nlm:aff></affiliation></author><author><name sortKey="Lauria, Francesco" sort="Lauria, Francesco" uniqKey="Lauria F" first="Francesco" last="Lauria">Francesco Lauria</name><affiliation><nlm:aff id="aff10">Hematology, Azienda Ospedaliera Universitaria Senese, Siena, Italy;</nlm:aff></affiliation></author><author><name sortKey="Lozanski, Gerard" sort="Lozanski, Gerard" uniqKey="Lozanski G" first="Gerard" last="Lozanski">Gerard Lozanski</name><affiliation><nlm:aff id="aff15">Department of Pathology, The Ohio State University, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Montserrat, Emili" sort="Montserrat, Emili" uniqKey="Montserrat E" first="Emili" last="Montserrat">Emili Montserrat</name><affiliation><nlm:aff id="aff16">Department of Hematology, Hospital Clinic, University of Barcelona, Barcelona, Spain;</nlm:aff></affiliation></author><author><name sortKey="Parikh, Sameer A" sort="Parikh, Sameer A" uniqKey="Parikh S" first="Sameer A." last="Parikh">Sameer A. Parikh</name><affiliation><nlm:aff id="aff5">Division of Hematology, Mayo Clinic, Rochester, MN;</nlm:aff></affiliation></author><author><name sortKey="Park, Jae H" sort="Park, Jae H" uniqKey="Park J" first="Jae H." last="Park">Jae H. Park</name><affiliation><nlm:aff id="aff2">Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;</nlm:aff></affiliation></author><author><name sortKey="Polliack, Aaron" sort="Polliack, Aaron" uniqKey="Polliack A" first="Aaron" last="Polliack">Aaron Polliack</name><affiliation><nlm:aff id="aff17">Department of Hematology, Hadassah University Hospital and Hebrew University Medical School, Jerusalem, Israel;</nlm:aff></affiliation></author><author><name sortKey="Quest, Graeme R" sort="Quest, Graeme R" uniqKey="Quest G" first="Graeme R." last="Quest">Graeme R. Quest</name><affiliation><nlm:aff id="aff18">Department of Laboratory Medicine and Pathology, University Health Network, Toronto, ON, Canada;</nlm:aff></affiliation></author><author><name sortKey="Rai, Kanti R" sort="Rai, Kanti R" uniqKey="Rai K" first="Kanti R." last="Rai">Kanti R. Rai</name><affiliation><nlm:aff id="aff4">Department of Medicine, Hofstra North Shore-Long Island Jewish School of Medicine, Hofstra University, Hempstead, NY;</nlm:aff></affiliation></author><author><name sortKey="Ravandi, Farhad" sort="Ravandi, Farhad" uniqKey="Ravandi F" first="Farhad" last="Ravandi">Farhad Ravandi</name><affiliation><nlm:aff id="aff19">Section of Developmental Therapeutics, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX;</nlm:aff></affiliation></author><author><name sortKey="Robak, Tadeusz" sort="Robak, Tadeusz" uniqKey="Robak T" first="Tadeusz" last="Robak">Tadeusz Robak</name><affiliation><nlm:aff id="aff20">Department of Hematology, Medical University of Lodz, Lodz, Poland;</nlm:aff></affiliation></author><author><name sortKey="Saven, Alan" sort="Saven, Alan" uniqKey="Saven A" first="Alan" last="Saven">Alan Saven</name><affiliation><nlm:aff id="aff21">Division of Hematology and Oncology, Scripps Clinic, La Jolla, CA;</nlm:aff></affiliation></author><author><name sortKey="Seymour, John F" sort="Seymour, John F" uniqKey="Seymour J" first="John F." last="Seymour">John F. Seymour</name><affiliation><nlm:aff id="aff22">Haematology Department, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia;</nlm:aff></affiliation></author><author><name sortKey="Tadmor, Tamar" sort="Tadmor, Tamar" uniqKey="Tadmor T" first="Tamar" last="Tadmor">Tamar Tadmor</name><affiliation><nlm:aff id="aff23">Hematology Unit, Bnai-Zion Medical Center, and the Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel;</nlm:aff></affiliation></author><author><name sortKey="Tallman, Martin S" sort="Tallman, Martin S" uniqKey="Tallman M" first="Martin S." last="Tallman">Martin S. Tallman</name><affiliation><nlm:aff id="aff2">Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;</nlm:aff></affiliation></author><author><name sortKey="Tam, Constantine" sort="Tam, Constantine" uniqKey="Tam C" first="Constantine" last="Tam">Constantine Tam</name><affiliation><nlm:aff id="aff22">Haematology Department, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia;</nlm:aff></affiliation></author><author><name sortKey="Tiacci, Enrico" sort="Tiacci, Enrico" uniqKey="Tiacci E" first="Enrico" last="Tiacci">Enrico Tiacci</name><affiliation><nlm:aff id="aff24">Institute of Hematology, Department of Medicine, University and Hospital of Perugia, Perugia, Italy;</nlm:aff></affiliation></author><author><name sortKey="Troussard, Xavier" sort="Troussard, Xavier" uniqKey="Troussard X" first="Xavier" last="Troussard">Xavier Troussard</name><affiliation><nlm:aff id="aff25">Department of Hematology, Centre Hospitalier Universitaire Côte de Nacre, Caen, France;</nlm:aff></affiliation></author><author><name sortKey="Zent, Clive S" sort="Zent, Clive S" uniqKey="Zent C" first="Clive S." last="Zent">Clive S. Zent</name><affiliation><nlm:aff id="aff26">James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY;</nlm:aff></affiliation></author><author><name sortKey="Zenz, Thorsten" sort="Zenz, Thorsten" uniqKey="Zenz T" first="Thorsten" last="Zenz">Thorsten Zenz</name><affiliation><nlm:aff wicri:cut="; and" id="aff27">Department of Molecular Therapy in Hematology and Oncology, National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Zinzani, Pier Luigi" sort="Zinzani, Pier Luigi" uniqKey="Zinzani P" first="Pier Luigi" last="Zinzani">Pier Luigi Zinzani</name><affiliation><nlm:aff id="aff28">Institute of Hematology “Seràgnoli,” University of Bologna, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Falini, Brunangelo" sort="Falini, Brunangelo" uniqKey="Falini B" first="Brunangelo" last="Falini">Brunangelo Falini</name><affiliation><nlm:aff id="aff24">Institute of Hematology, Department of Medicine, University and Hospital of Perugia, Perugia, Italy;</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27903528</idno><idno type="pmc">5290982</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290982</idno><idno type="RBID">PMC:5290982</idno><idno type="doi">10.1182/blood-2016-01-689422</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">002E75</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E75</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia</title><author><name sortKey="Grever, Michael R" sort="Grever, Michael R" uniqKey="Grever M" first="Michael R." last="Grever">Michael R. Grever</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Abdel Wahab, Omar" sort="Abdel Wahab, Omar" uniqKey="Abdel Wahab O" first="Omar" last="Abdel-Wahab">Omar Abdel-Wahab</name><affiliation><nlm:aff id="aff2">Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;</nlm:aff></affiliation></author><author><name sortKey="Andritsos, Leslie A" sort="Andritsos, Leslie A" uniqKey="Andritsos L" first="Leslie A." last="Andritsos">Leslie A. Andritsos</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Banerji, Versha" sort="Banerji, Versha" uniqKey="Banerji V" first="Versha" last="Banerji">Versha Banerji</name><affiliation><nlm:aff id="aff3">Section of Hematology/Oncology, University of Manitoba, Winnipeg, MB, Canada;</nlm:aff></affiliation></author><author><name sortKey="Barrientos, Jacqueline" sort="Barrientos, Jacqueline" uniqKey="Barrientos J" first="Jacqueline" last="Barrientos">Jacqueline Barrientos</name><affiliation><nlm:aff id="aff4">Department of Medicine, Hofstra North Shore-Long Island Jewish School of Medicine, Hofstra University, Hempstead, NY;</nlm:aff></affiliation></author><author><name sortKey="Blachly, James S" sort="Blachly, James S" uniqKey="Blachly J" first="James S." last="Blachly">James S. Blachly</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Call, Timothy G" sort="Call, Timothy G" uniqKey="Call T" first="Timothy G." last="Call">Timothy G. Call</name><affiliation><nlm:aff id="aff5">Division of Hematology, Mayo Clinic, Rochester, MN;</nlm:aff></affiliation></author><author><name sortKey="Catovsky, Daniel" sort="Catovsky, Daniel" uniqKey="Catovsky D" first="Daniel" last="Catovsky">Daniel Catovsky</name><affiliation><nlm:aff id="aff6">Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom;</nlm:aff></affiliation></author><author><name sortKey="Dearden, Claire" sort="Dearden, Claire" uniqKey="Dearden C" first="Claire" last="Dearden">Claire Dearden</name><affiliation><nlm:aff id="aff7">Department of Haemato-Oncology, Royal Marsden Biomedical Research Centre, London, United Kingdom;</nlm:aff></affiliation></author><author><name sortKey="Demeter, Judit" sort="Demeter, Judit" uniqKey="Demeter J" first="Judit" last="Demeter">Judit Demeter</name><affiliation><nlm:aff id="aff8">First Department of Internal Medicine, Semmelweis University, Budapest, Hungary;</nlm:aff></affiliation></author><author><name sortKey="Else, Monica" sort="Else, Monica" uniqKey="Else M" first="Monica" last="Else">Monica Else</name><affiliation><nlm:aff id="aff6">Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom;</nlm:aff></affiliation></author><author><name sortKey="Forconi, Francesco" sort="Forconi, Francesco" uniqKey="Forconi F" first="Francesco" last="Forconi">Francesco Forconi</name><affiliation><nlm:aff id="aff9">Haematology Department, University Hospital Trust and Cancer Sciences Unit, Cancer Research UK and National Institute for Health Research Experimental Cancer Medicine Centres, Faculty of Medicine, University of Southampton, Southampton, United Kingdom;</nlm:aff></affiliation></author><author><name sortKey="Gozzetti, Alessandro" sort="Gozzetti, Alessandro" uniqKey="Gozzetti A" first="Alessandro" last="Gozzetti">Alessandro Gozzetti</name><affiliation><nlm:aff id="aff10">Hematology, Azienda Ospedaliera Universitaria Senese, Siena, Italy;</nlm:aff></affiliation></author><author><name sortKey="Ho, Anthony D" sort="Ho, Anthony D" uniqKey="Ho A" first="Anthony D." last="Ho">Anthony D. Ho</name><affiliation><nlm:aff id="aff11">Department of Medicine V, University of Heidelberg, Heidelberg, Germany;</nlm:aff></affiliation></author><author><name sortKey="Johnston, James B" sort="Johnston, James B" uniqKey="Johnston J" first="James B." last="Johnston">James B. Johnston</name><affiliation><nlm:aff id="aff3">Section of Hematology/Oncology, University of Manitoba, Winnipeg, MB, Canada;</nlm:aff></affiliation></author><author><name sortKey="Jones, Jeffrey" sort="Jones, Jeffrey" uniqKey="Jones J" first="Jeffrey" last="Jones">Jeffrey Jones</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Juliusson, Gunnar" sort="Juliusson, Gunnar" uniqKey="Juliusson G" first="Gunnar" last="Juliusson">Gunnar Juliusson</name><affiliation><nlm:aff id="aff12">Department of Hematology, Skåne University Hospital and Stem Cell Center, Lund University, Lund, Sweden;</nlm:aff></affiliation></author><author><name sortKey="Kraut, Eric" sort="Kraut, Eric" uniqKey="Kraut E" first="Eric" last="Kraut">Eric Kraut</name><affiliation><nlm:aff id="aff1">Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Kreitman, Robert J" sort="Kreitman, Robert J" uniqKey="Kreitman R" first="Robert J." last="Kreitman">Robert J. Kreitman</name><affiliation><nlm:aff id="aff13">Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD;</nlm:aff></affiliation></author><author><name sortKey="Larratt, Loree" sort="Larratt, Loree" uniqKey="Larratt L" first="Loree" last="Larratt">Loree Larratt</name><affiliation><nlm:aff id="aff14">Department of Medicine, University of Alberta, Edmonton, AB, Canada;</nlm:aff></affiliation></author><author><name sortKey="Lauria, Francesco" sort="Lauria, Francesco" uniqKey="Lauria F" first="Francesco" last="Lauria">Francesco Lauria</name><affiliation><nlm:aff id="aff10">Hematology, Azienda Ospedaliera Universitaria Senese, Siena, Italy;</nlm:aff></affiliation></author><author><name sortKey="Lozanski, Gerard" sort="Lozanski, Gerard" uniqKey="Lozanski G" first="Gerard" last="Lozanski">Gerard Lozanski</name><affiliation><nlm:aff id="aff15">Department of Pathology, The Ohio State University, Columbus, OH;</nlm:aff></affiliation></author><author><name sortKey="Montserrat, Emili" sort="Montserrat, Emili" uniqKey="Montserrat E" first="Emili" last="Montserrat">Emili Montserrat</name><affiliation><nlm:aff id="aff16">Department of Hematology, Hospital Clinic, University of Barcelona, Barcelona, Spain;</nlm:aff></affiliation></author><author><name sortKey="Parikh, Sameer A" sort="Parikh, Sameer A" uniqKey="Parikh S" first="Sameer A." last="Parikh">Sameer A. Parikh</name><affiliation><nlm:aff id="aff5">Division of Hematology, Mayo Clinic, Rochester, MN;</nlm:aff></affiliation></author><author><name sortKey="Park, Jae H" sort="Park, Jae H" uniqKey="Park J" first="Jae H." last="Park">Jae H. Park</name><affiliation><nlm:aff id="aff2">Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;</nlm:aff></affiliation></author><author><name sortKey="Polliack, Aaron" sort="Polliack, Aaron" uniqKey="Polliack A" first="Aaron" last="Polliack">Aaron Polliack</name><affiliation><nlm:aff id="aff17">Department of Hematology, Hadassah University Hospital and Hebrew University Medical School, Jerusalem, Israel;</nlm:aff></affiliation></author><author><name sortKey="Quest, Graeme R" sort="Quest, Graeme R" uniqKey="Quest G" first="Graeme R." last="Quest">Graeme R. Quest</name><affiliation><nlm:aff id="aff18">Department of Laboratory Medicine and Pathology, University Health Network, Toronto, ON, Canada;</nlm:aff></affiliation></author><author><name sortKey="Rai, Kanti R" sort="Rai, Kanti R" uniqKey="Rai K" first="Kanti R." last="Rai">Kanti R. Rai</name><affiliation><nlm:aff id="aff4">Department of Medicine, Hofstra North Shore-Long Island Jewish School of Medicine, Hofstra University, Hempstead, NY;</nlm:aff></affiliation></author><author><name sortKey="Ravandi, Farhad" sort="Ravandi, Farhad" uniqKey="Ravandi F" first="Farhad" last="Ravandi">Farhad Ravandi</name><affiliation><nlm:aff id="aff19">Section of Developmental Therapeutics, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX;</nlm:aff></affiliation></author><author><name sortKey="Robak, Tadeusz" sort="Robak, Tadeusz" uniqKey="Robak T" first="Tadeusz" last="Robak">Tadeusz Robak</name><affiliation><nlm:aff id="aff20">Department of Hematology, Medical University of Lodz, Lodz, Poland;</nlm:aff></affiliation></author><author><name sortKey="Saven, Alan" sort="Saven, Alan" uniqKey="Saven A" first="Alan" last="Saven">Alan Saven</name><affiliation><nlm:aff id="aff21">Division of Hematology and Oncology, Scripps Clinic, La Jolla, CA;</nlm:aff></affiliation></author><author><name sortKey="Seymour, John F" sort="Seymour, John F" uniqKey="Seymour J" first="John F." last="Seymour">John F. Seymour</name><affiliation><nlm:aff id="aff22">Haematology Department, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia;</nlm:aff></affiliation></author><author><name sortKey="Tadmor, Tamar" sort="Tadmor, Tamar" uniqKey="Tadmor T" first="Tamar" last="Tadmor">Tamar Tadmor</name><affiliation><nlm:aff id="aff23">Hematology Unit, Bnai-Zion Medical Center, and the Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel;</nlm:aff></affiliation></author><author><name sortKey="Tallman, Martin S" sort="Tallman, Martin S" uniqKey="Tallman M" first="Martin S." last="Tallman">Martin S. Tallman</name><affiliation><nlm:aff id="aff2">Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;</nlm:aff></affiliation></author><author><name sortKey="Tam, Constantine" sort="Tam, Constantine" uniqKey="Tam C" first="Constantine" last="Tam">Constantine Tam</name><affiliation><nlm:aff id="aff22">Haematology Department, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia;</nlm:aff></affiliation></author><author><name sortKey="Tiacci, Enrico" sort="Tiacci, Enrico" uniqKey="Tiacci E" first="Enrico" last="Tiacci">Enrico Tiacci</name><affiliation><nlm:aff id="aff24">Institute of Hematology, Department of Medicine, University and Hospital of Perugia, Perugia, Italy;</nlm:aff></affiliation></author><author><name sortKey="Troussard, Xavier" sort="Troussard, Xavier" uniqKey="Troussard X" first="Xavier" last="Troussard">Xavier Troussard</name><affiliation><nlm:aff id="aff25">Department of Hematology, Centre Hospitalier Universitaire Côte de Nacre, Caen, France;</nlm:aff></affiliation></author><author><name sortKey="Zent, Clive S" sort="Zent, Clive S" uniqKey="Zent C" first="Clive S." last="Zent">Clive S. Zent</name><affiliation><nlm:aff id="aff26">James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY;</nlm:aff></affiliation></author><author><name sortKey="Zenz, Thorsten" sort="Zenz, Thorsten" uniqKey="Zenz T" first="Thorsten" last="Zenz">Thorsten Zenz</name><affiliation><nlm:aff wicri:cut="; and" id="aff27">Department of Molecular Therapy in Hematology and Oncology, National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff></affiliation></author><author><name sortKey="Zinzani, Pier Luigi" sort="Zinzani, Pier Luigi" uniqKey="Zinzani P" first="Pier Luigi" last="Zinzani">Pier Luigi Zinzani</name><affiliation><nlm:aff id="aff28">Institute of Hematology “Seràgnoli,” University of Bologna, Bologna, Italy</nlm:aff></affiliation></author><author><name sortKey="Falini, Brunangelo" sort="Falini, Brunangelo" uniqKey="Falini B" first="Brunangelo" last="Falini">Brunangelo Falini</name><affiliation><nlm:aff id="aff24">Institute of Hematology, Department of Medicine, University and Hospital of Perugia, Perugia, Italy;</nlm:aff></affiliation></author></analytic><series><title level="j">Blood</title><idno type="ISSN">0006-4971</idno><idno type="eISSN">1528-0020</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Hairy cell leukemia is an uncommon hematologic malignancy characterized by pancytopenia and marked susceptibility to infection. Tremendous progress in the management of patients with this disease has resulted in high response rates and improved survival, yet relapse and an appropriate approach to re-treatment present continuing areas for research. The disease and its effective treatment are associated with immunosuppression. Because more patients are being treated with alternative programs, comparison of results will require general agreement on definitions of response, relapse, and methods of determining minimal residual disease. The development of internationally accepted, reproducible criteria is of paramount importance in evaluating and comparing clinical trials to provide optimal care. Despite the success achieved in managing these patients, continued participation in available clinical trials in the first-line and particularly in the relapse setting is highly recommended. The Hairy Cell Leukemia Foundation convened an international conference to provide common definitions and structure to guide current management. There is substantial opportunity for continued research in this disease. In addition to the importance of optimizing the prevention and management of the serious risk of infection, organized evaluations of minimal residual disease and treatment at relapse offer ample opportunities for clinical research. Finally, a scholarly evaluation of quality of life in the increasing number of survivors of this now manageable chronic illness merits further study. The development of consensus guidelines for this disease offers a framework for continued enhancement of the outcome for patients.</p></div></front></TEI><pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Blood</journal-id><journal-id journal-id-type="iso-abbrev">Blood</journal-id><journal-id journal-id-type="hwp">bloodjournal</journal-id><journal-id journal-id-type="pmc">blood</journal-id><journal-id journal-id-type="publisher-id">Blood</journal-id><journal-title-group><journal-title>Blood</journal-title></journal-title-group><issn pub-type="ppub">0006-4971</issn><issn pub-type="epub">1528-0020</issn><publisher><publisher-name>American Society of Hematology</publisher-name><publisher-loc>Washington, DC</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27903528</article-id><article-id pub-id-type="pmc">5290982</article-id><article-id pub-id-type="publisher-id">2016/689422</article-id><article-id pub-id-type="doi">10.1182/blood-2016-01-689422</article-id><article-categories><subj-group subj-group-type="hwp-journal-coll"><subject>5</subject><subject>29</subject><subject>8</subject><subject>39</subject></subj-group><subj-group subj-group-type="heading"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title>Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Grever</surname><given-names>Michael R.</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Abdel-Wahab</surname><given-names>Omar</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Andritsos</surname><given-names>Leslie A.</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Banerji</surname><given-names>Versha</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Barrientos</surname><given-names>Jacqueline</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Blachly</surname><given-names>James S.</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Call</surname><given-names>Timothy G.</given-names></name><xref ref-type="aff" rid="aff5">5</xref></contrib><contrib contrib-type="author"><name><surname>Catovsky</surname><given-names>Daniel</given-names></name><xref ref-type="aff" rid="aff6">6</xref></contrib><contrib contrib-type="author"><name><surname>Dearden</surname><given-names>Claire</given-names></name><xref ref-type="aff" rid="aff7">7</xref></contrib><contrib contrib-type="author"><name><surname>Demeter</surname><given-names>Judit</given-names></name><xref ref-type="aff" rid="aff8">8</xref></contrib><contrib contrib-type="author"><name><surname>Else</surname><given-names>Monica</given-names></name><xref ref-type="aff" rid="aff6">6</xref></contrib><contrib contrib-type="author"><name><surname>Forconi</surname><given-names>Francesco</given-names></name><xref ref-type="aff" rid="aff9">9</xref></contrib><contrib contrib-type="author"><name><surname>Gozzetti</surname><given-names>Alessandro</given-names></name><xref ref-type="aff" rid="aff10">10</xref></contrib><contrib contrib-type="author"><name><surname>Ho</surname><given-names>Anthony D.</given-names></name><xref ref-type="aff" rid="aff11">11</xref></contrib><contrib contrib-type="author"><name><surname>Johnston</surname><given-names>James B.</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Jones</surname><given-names>Jeffrey</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Juliusson</surname><given-names>Gunnar</given-names></name><xref ref-type="aff" rid="aff12">12</xref></contrib><contrib contrib-type="author"><name><surname>Kraut</surname><given-names>Eric</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Kreitman</surname><given-names>Robert J.</given-names></name><xref ref-type="aff" rid="aff13">13</xref></contrib><contrib contrib-type="author"><name><surname>Larratt</surname><given-names>Loree</given-names></name><xref ref-type="aff" rid="aff14">14</xref></contrib><contrib contrib-type="author"><name><surname>Lauria</surname><given-names>Francesco</given-names></name><xref ref-type="aff" rid="aff10">10</xref></contrib><contrib contrib-type="author"><name><surname>Lozanski</surname><given-names>Gerard</given-names></name><xref ref-type="aff" rid="aff15">15</xref></contrib><contrib contrib-type="author"><name><surname>Montserrat</surname><given-names>Emili</given-names></name><xref ref-type="aff" rid="aff16">16</xref></contrib><contrib contrib-type="author"><name><surname>Parikh</surname><given-names>Sameer A.</given-names></name><xref ref-type="aff" rid="aff5">5</xref></contrib><contrib contrib-type="author"><name><surname>Park</surname><given-names>Jae H.</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Polliack</surname><given-names>Aaron</given-names></name><xref ref-type="aff" rid="aff17">17</xref></contrib><contrib contrib-type="author"><name><surname>Quest</surname><given-names>Graeme R.</given-names></name><xref ref-type="aff" rid="aff18">18</xref></contrib><contrib contrib-type="author"><name><surname>Rai</surname><given-names>Kanti R.</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Ravandi</surname><given-names>Farhad</given-names></name><xref ref-type="aff" rid="aff19">19</xref></contrib><contrib contrib-type="author"><name><surname>Robak</surname><given-names>Tadeusz</given-names></name><xref ref-type="aff" rid="aff20">20</xref></contrib><contrib contrib-type="author"><name><surname>Saven</surname><given-names>Alan</given-names></name><xref ref-type="aff" rid="aff21">21</xref></contrib><contrib contrib-type="author"><name><surname>Seymour</surname><given-names>John F.</given-names></name><xref ref-type="aff" rid="aff22">22</xref></contrib><contrib contrib-type="author"><name><surname>Tadmor</surname><given-names>Tamar</given-names></name><xref ref-type="aff" rid="aff23">23</xref></contrib><contrib contrib-type="author"><name><surname>Tallman</surname><given-names>Martin S.</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Tam</surname><given-names>Constantine</given-names></name><xref ref-type="aff" rid="aff22">22</xref></contrib><contrib contrib-type="author"><name><surname>Tiacci</surname><given-names>Enrico</given-names></name><xref ref-type="aff" rid="aff24">24</xref></contrib><contrib contrib-type="author"><name><surname>Troussard</surname><given-names>Xavier</given-names></name><xref ref-type="aff" rid="aff25">25</xref></contrib><contrib contrib-type="author"><name><surname>Zent</surname><given-names>Clive S.</given-names></name><xref ref-type="aff" rid="aff26">26</xref></contrib><contrib contrib-type="author"><name><surname>Zenz</surname><given-names>Thorsten</given-names></name><xref ref-type="aff" rid="aff27">27</xref></contrib><contrib contrib-type="author"><name><surname>Zinzani</surname><given-names>Pier Luigi</given-names></name><xref ref-type="aff" rid="aff28">28</xref></contrib><contrib contrib-type="author"><name><surname>Falini</surname><given-names>Brunangelo</given-names></name><xref ref-type="aff" rid="aff24">24</xref></contrib><aff id="aff1"><label>1</label>Division of Hematology, Department of Internal Medicine, The Ohio State University James Cancer Hospital, Columbus, OH;</aff><aff id="aff2"><label>2</label>Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY;</aff><aff id="aff3"><label>3</label>Section of Hematology/Oncology, University of Manitoba, Winnipeg, MB, Canada;</aff><aff id="aff4"><label>4</label>Department of Medicine, Hofstra North Shore-Long Island Jewish School of Medicine, Hofstra University, Hempstead, NY;</aff><aff id="aff5"><label>5</label>Division of Hematology, Mayo Clinic, Rochester, MN;</aff><aff id="aff6"><label>6</label>Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom;</aff><aff id="aff7"><label>7</label>Department of Haemato-Oncology, Royal Marsden Biomedical Research Centre, London, United Kingdom;</aff><aff id="aff8"><label>8</label>First Department of Internal Medicine, Semmelweis University, Budapest, Hungary;</aff><aff id="aff9"><label>9</label>Haematology Department, University Hospital Trust and Cancer Sciences Unit, Cancer Research UK and National Institute for Health Research Experimental Cancer Medicine Centres, Faculty of Medicine, University of Southampton, Southampton, United Kingdom;</aff><aff id="aff10"><label>10</label>Hematology, Azienda Ospedaliera Universitaria Senese, Siena, Italy;</aff><aff id="aff11"><label>11</label>Department of Medicine V, University of Heidelberg, Heidelberg, Germany;</aff><aff id="aff12"><label>12</label>Department of Hematology, Skåne University Hospital and Stem Cell Center, Lund University, Lund, Sweden;</aff><aff id="aff13"><label>13</label>Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD;</aff><aff id="aff14"><label>14</label>Department of Medicine, University of Alberta, Edmonton, AB, Canada;</aff><aff id="aff15"><label>15</label>Department of Pathology, The Ohio State University, Columbus, OH;</aff><aff id="aff16"><label>16</label>Department of Hematology, Hospital Clinic, University of Barcelona, Barcelona, Spain;</aff><aff id="aff17"><label>17</label>Department of Hematology, Hadassah University Hospital and Hebrew University Medical School, Jerusalem, Israel;</aff><aff id="aff18"><label>18</label>Department of Laboratory Medicine and Pathology, University Health Network, Toronto, ON, Canada;</aff><aff id="aff19"><label>19</label>Section of Developmental Therapeutics, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX;</aff><aff id="aff20"><label>20</label>Department of Hematology, Medical University of Lodz, Lodz, Poland;</aff><aff id="aff21"><label>21</label>Division of Hematology and Oncology, Scripps Clinic, La Jolla, CA;</aff><aff id="aff22"><label>22</label>Haematology Department, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia;</aff><aff id="aff23"><label>23</label>Hematology Unit, Bnai-Zion Medical Center, and the Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel;</aff><aff id="aff24"><label>24</label>Institute of Hematology, Department of Medicine, University and Hospital of Perugia, Perugia, Italy;</aff><aff id="aff25"><label>25</label>Department of Hematology, Centre Hospitalier Universitaire Côte de Nacre, Caen, France;</aff><aff id="aff26"><label>26</label>James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY;</aff><aff id="aff27"><label>27</label>Department of Molecular Therapy in Hematology and Oncology, National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany; and</aff><aff id="aff28"><label>28</label>Institute of Hematology “Seràgnoli,” University of Bologna, Bologna, Italy</aff></contrib-group><pub-date pub-type="ppub"><day>2</day><month>2</month><year>2017</year></pub-date><pub-date pub-type="epreprint"><day>30</day><month>11</month><year>2016</year></pub-date><pub-date pub-type="pmc-release"><day>2</day><month>2</month><year>2017</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
<volume>129</volume><issue>5</issue><fpage>553</fpage><lpage>560</lpage><history><date date-type="received"><day>21</day><month>1</month><year>2016</year></date><date date-type="accepted"><day>06</day><month>11</month><year>2016</year></date></history><permissions><copyright-year>2017</copyright-year></permissions><self-uri xlink:title="pdf" xlink:href="blood689422.pdf"></self-uri><abstract><p>Hairy cell leukemia is an uncommon hematologic malignancy characterized by pancytopenia and marked susceptibility to infection. Tremendous progress in the management of patients with this disease has resulted in high response rates and improved survival, yet relapse and an appropriate approach to re-treatment present continuing areas for research. The disease and its effective treatment are associated with immunosuppression. Because more patients are being treated with alternative programs, comparison of results will require general agreement on definitions of response, relapse, and methods of determining minimal residual disease. The development of internationally accepted, reproducible criteria is of paramount importance in evaluating and comparing clinical trials to provide optimal care. Despite the success achieved in managing these patients, continued participation in available clinical trials in the first-line and particularly in the relapse setting is highly recommended. The Hairy Cell Leukemia Foundation convened an international conference to provide common definitions and structure to guide current management. There is substantial opportunity for continued research in this disease. In addition to the importance of optimizing the prevention and management of the serious risk of infection, organized evaluations of minimal residual disease and treatment at relapse offer ample opportunities for clinical research. Finally, a scholarly evaluation of quality of life in the increasing number of survivors of this now manageable chronic illness merits further study. The development of consensus guidelines for this disease offers a framework for continued enhancement of the outcome for patients.</p></abstract><counts><page-count count="8"></page-count></counts><custom-meta-group><custom-meta><meta-name>access</meta-name><meta-value>free</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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