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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies</title><author><name sortKey="Kitahara, Cari M" sort="Kitahara, Cari M" uniqKey="Kitahara C" first="Cari M." last="Kitahara">Cari M. Kitahara</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Mccullough, Marjorie L" sort="Mccullough, Marjorie L" uniqKey="Mccullough M" first="Marjorie L." last="Mccullough">Marjorie L. Mccullough</name><affiliation><nlm:aff id="aff2"></nlm:aff></affiliation></author><author><name sortKey="Franceschi, Silvia" sort="Franceschi, Silvia" uniqKey="Franceschi S" first="Silvia" last="Franceschi">Silvia Franceschi</name><affiliation><nlm:aff id="aff3"></nlm:aff></affiliation></author><author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name><affiliation><nlm:aff id="aff3"></nlm:aff></affiliation></author><author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name><affiliation><nlm:aff id="aff4"></nlm:aff></affiliation></author><author><name sortKey="Neta, Gila" sort="Neta, Gila" uniqKey="Neta G" first="Gila" last="Neta">Gila Neta</name><affiliation><nlm:aff id="aff5"></nlm:aff></affiliation></author><author><name sortKey="Olov Adami, Hans" sort="Olov Adami, Hans" uniqKey="Olov Adami H" first="Hans" last="Olov Adami">Hans Olov Adami</name><affiliation><nlm:aff id="aff6"></nlm:aff></affiliation><affiliation><nlm:aff id="aff7"></nlm:aff></affiliation></author><author><name sortKey="Anderson, Kristin" sort="Anderson, Kristin" uniqKey="Anderson K" first="Kristin" last="Anderson">Kristin Anderson</name><affiliation><nlm:aff id="aff8"></nlm:aff></affiliation><affiliation><nlm:aff id="aff9"></nlm:aff></affiliation></author><author><name sortKey="Andreotti, Gabriella" sort="Andreotti, Gabriella" uniqKey="Andreotti G" first="Gabriella" last="Andreotti">Gabriella Andreotti</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Beane Freeman, Laura E" sort="Beane Freeman, Laura E" uniqKey="Beane Freeman L" first="Laura E." last="Beane Freeman">Laura E. Beane Freeman</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name><affiliation><nlm:aff id="aff10"></nlm:aff></affiliation></author><author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E." last="Buring">Julie E. Buring</name><affiliation><nlm:aff id="aff7"></nlm:aff></affiliation><affiliation><nlm:aff id="aff11"></nlm:aff></affiliation></author><author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name><affiliation><nlm:aff id="aff12"></nlm:aff></affiliation></author><author><name sortKey="De Roo, Lisa A" sort="De Roo, Lisa A" uniqKey="De Roo L" first="Lisa A." last="De Roo">Lisa A. De Roo</name><affiliation><nlm:aff id="aff13"></nlm:aff></affiliation><affiliation><nlm:aff id="aff14"></nlm:aff></affiliation></author><author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name><affiliation><nlm:aff id="aff15"></nlm:aff></affiliation></author><author><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J. Michael" last="Gaziano">J. Michael Gaziano</name><affiliation><nlm:aff id="aff11"></nlm:aff></affiliation><affiliation><nlm:aff id="aff16"></nlm:aff></affiliation><affiliation><nlm:aff id="aff17"></nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="aff18"></nlm:aff></affiliation><affiliation><nlm:aff id="aff19"></nlm:aff></affiliation></author><author><name sortKey="H Kansson, Niclas" sort="H Kansson, Niclas" uniqKey="H Kansson N" first="Niclas" last="H Kansson">Niclas H Kansson</name><affiliation><nlm:aff id="aff4"></nlm:aff></affiliation></author><author><name sortKey="Horn Ross, Pamela L" sort="Horn Ross, Pamela L" uniqKey="Horn Ross P" first="Pamela L." last="Horn-Ross">Pamela L. Horn-Ross</name><affiliation><nlm:aff id="aff20"></nlm:aff></affiliation></author><author><name sortKey="Kirsh, Vicki A" sort="Kirsh, Vicki A" uniqKey="Kirsh V" first="Vicki A." last="Kirsh">Vicki A. Kirsh</name><affiliation><nlm:aff id="aff21"></nlm:aff></affiliation><affiliation><nlm:aff id="aff22"></nlm:aff></affiliation></author><author><name sortKey="Linet, Martha S" sort="Linet, Martha S" uniqKey="Linet M" first="Martha S." last="Linet">Martha S. Linet</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Macinnis, Robert J" sort="Macinnis, Robert J" uniqKey="Macinnis R" first="Robert J." last="Macinnis">Robert J. Macinnis</name><affiliation><nlm:aff id="aff18"></nlm:aff></affiliation><affiliation><nlm:aff id="aff19"></nlm:aff></affiliation></author><author><name sortKey="Orsini, Nicola" sort="Orsini, Nicola" uniqKey="Orsini N" first="Nicola" last="Orsini">Nicola Orsini</name><affiliation><nlm:aff id="aff4"></nlm:aff></affiliation></author><author><name sortKey="Park, Yikyung" sort="Park, Yikyung" uniqKey="Park Y" first="Yikyung" last="Park">Yikyung Park</name><affiliation><nlm:aff id="aff23"></nlm:aff></affiliation></author><author><name sortKey="Patel, Alpa V" sort="Patel, Alpa V" uniqKey="Patel A" first="Alpa V." last="Patel">Alpa V. Patel</name><affiliation><nlm:aff id="aff2"></nlm:aff></affiliation></author><author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P." last="Purdue">Mark P. Purdue</name><affiliation><nlm:aff id="aff24"></nlm:aff></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation><nlm:aff id="aff25"></nlm:aff></affiliation></author><author><name sortKey="Robien, Kimberly" sort="Robien, Kimberly" uniqKey="Robien K" first="Kimberly" last="Robien">Kimberly Robien</name><affiliation><nlm:aff id="aff26"></nlm:aff></affiliation></author><author><name sortKey="Rohan, Thomas" sort="Rohan, Thomas" uniqKey="Rohan T" first="Thomas" last="Rohan">Thomas Rohan</name><affiliation><nlm:aff id="aff27"></nlm:aff></affiliation></author><author><name sortKey="Sandler, Dale P" sort="Sandler, Dale P" uniqKey="Sandler D" first="Dale P." last="Sandler">Dale P. Sandler</name><affiliation><nlm:aff id="aff14"></nlm:aff></affiliation></author><author><name sortKey="Schairer, Catherine" sort="Schairer, Catherine" uniqKey="Schairer C" first="Catherine" last="Schairer">Catherine Schairer</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Schneider, Arthur B" sort="Schneider, Arthur B" uniqKey="Schneider A" first="Arthur B." last="Schneider">Arthur B. Schneider</name><affiliation><nlm:aff id="aff28"></nlm:aff></affiliation></author><author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D." last="Sesso">Howard D. Sesso</name><affiliation><nlm:aff id="aff7"></nlm:aff></affiliation><affiliation><nlm:aff id="aff11"></nlm:aff></affiliation><affiliation><nlm:aff id="aff16"></nlm:aff></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation><nlm:aff id="aff29"></nlm:aff></affiliation></author><author><name sortKey="Singh, Pramil N" sort="Singh, Pramil N" uniqKey="Singh P" first="Pramil N." last="Singh">Pramil N. Singh</name><affiliation><nlm:aff id="aff30"></nlm:aff></affiliation></author><author><name sortKey="Van Den Brandt, Piet A" sort="Van Den Brandt, Piet A" uniqKey="Van Den Brandt P" first="Piet A." last="Van Den Brandt">Piet A. Van Den Brandt</name><affiliation><nlm:aff id="aff31"></nlm:aff></affiliation></author><author><name sortKey="Ward, Elizabeth" sort="Ward, Elizabeth" uniqKey="Ward E" first="Elizabeth" last="Ward">Elizabeth Ward</name><affiliation><nlm:aff id="aff32"></nlm:aff></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation><nlm:aff id="aff6"></nlm:aff></affiliation><affiliation><nlm:aff id="aff33"></nlm:aff></affiliation><affiliation><nlm:aff id="aff34"></nlm:aff></affiliation><affiliation><nlm:aff id="aff35"></nlm:aff></affiliation></author><author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><affiliation><nlm:aff id="aff36"></nlm:aff></affiliation><affiliation><nlm:aff id="aff37"></nlm:aff></affiliation></author><author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name><affiliation><nlm:aff id="aff15"></nlm:aff></affiliation></author><author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name><affiliation><nlm:aff id="aff38"></nlm:aff></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="aff29"></nlm:aff></affiliation></author><author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Berrington De Gonzalez, Amy" sort="Berrington De Gonzalez, Amy" uniqKey="Berrington De Gonzalez A" first="Amy" last="Berrington De González">Amy Berrington De González</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26756356</idno><idno type="pmc">4754509</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754509</idno><idno type="RBID">PMC:4754509</idno><idno type="doi">10.1089/thy.2015.0319</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000501</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000501</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies</title><author><name sortKey="Kitahara, Cari M" sort="Kitahara, Cari M" uniqKey="Kitahara C" first="Cari M." last="Kitahara">Cari M. Kitahara</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Mccullough, Marjorie L" sort="Mccullough, Marjorie L" uniqKey="Mccullough M" first="Marjorie L." last="Mccullough">Marjorie L. Mccullough</name><affiliation><nlm:aff id="aff2"></nlm:aff></affiliation></author><author><name sortKey="Franceschi, Silvia" sort="Franceschi, Silvia" uniqKey="Franceschi S" first="Silvia" last="Franceschi">Silvia Franceschi</name><affiliation><nlm:aff id="aff3"></nlm:aff></affiliation></author><author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name><affiliation><nlm:aff id="aff3"></nlm:aff></affiliation></author><author><name sortKey="Wolk, Alicja" sort="Wolk, Alicja" uniqKey="Wolk A" first="Alicja" last="Wolk">Alicja Wolk</name><affiliation><nlm:aff id="aff4"></nlm:aff></affiliation></author><author><name sortKey="Neta, Gila" sort="Neta, Gila" uniqKey="Neta G" first="Gila" last="Neta">Gila Neta</name><affiliation><nlm:aff id="aff5"></nlm:aff></affiliation></author><author><name sortKey="Olov Adami, Hans" sort="Olov Adami, Hans" uniqKey="Olov Adami H" first="Hans" last="Olov Adami">Hans Olov Adami</name><affiliation><nlm:aff id="aff6"></nlm:aff></affiliation><affiliation><nlm:aff id="aff7"></nlm:aff></affiliation></author><author><name sortKey="Anderson, Kristin" sort="Anderson, Kristin" uniqKey="Anderson K" first="Kristin" last="Anderson">Kristin Anderson</name><affiliation><nlm:aff id="aff8"></nlm:aff></affiliation><affiliation><nlm:aff id="aff9"></nlm:aff></affiliation></author><author><name sortKey="Andreotti, Gabriella" sort="Andreotti, Gabriella" uniqKey="Andreotti G" first="Gabriella" last="Andreotti">Gabriella Andreotti</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Beane Freeman, Laura E" sort="Beane Freeman, Laura E" uniqKey="Beane Freeman L" first="Laura E." last="Beane Freeman">Laura E. Beane Freeman</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name><affiliation><nlm:aff id="aff10"></nlm:aff></affiliation></author><author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E." last="Buring">Julie E. Buring</name><affiliation><nlm:aff id="aff7"></nlm:aff></affiliation><affiliation><nlm:aff id="aff11"></nlm:aff></affiliation></author><author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name><affiliation><nlm:aff id="aff12"></nlm:aff></affiliation></author><author><name sortKey="De Roo, Lisa A" sort="De Roo, Lisa A" uniqKey="De Roo L" first="Lisa A." last="De Roo">Lisa A. De Roo</name><affiliation><nlm:aff id="aff13"></nlm:aff></affiliation><affiliation><nlm:aff id="aff14"></nlm:aff></affiliation></author><author><name sortKey="Gao, Yu Tang" sort="Gao, Yu Tang" uniqKey="Gao Y" first="Yu-Tang" last="Gao">Yu-Tang Gao</name><affiliation><nlm:aff id="aff15"></nlm:aff></affiliation></author><author><name sortKey="Gaziano, J Michael" sort="Gaziano, J Michael" uniqKey="Gaziano J" first="J. Michael" last="Gaziano">J. Michael Gaziano</name><affiliation><nlm:aff id="aff11"></nlm:aff></affiliation><affiliation><nlm:aff id="aff16"></nlm:aff></affiliation><affiliation><nlm:aff id="aff17"></nlm:aff></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation><nlm:aff id="aff18"></nlm:aff></affiliation><affiliation><nlm:aff id="aff19"></nlm:aff></affiliation></author><author><name sortKey="H Kansson, Niclas" sort="H Kansson, Niclas" uniqKey="H Kansson N" first="Niclas" last="H Kansson">Niclas H Kansson</name><affiliation><nlm:aff id="aff4"></nlm:aff></affiliation></author><author><name sortKey="Horn Ross, Pamela L" sort="Horn Ross, Pamela L" uniqKey="Horn Ross P" first="Pamela L." last="Horn-Ross">Pamela L. Horn-Ross</name><affiliation><nlm:aff id="aff20"></nlm:aff></affiliation></author><author><name sortKey="Kirsh, Vicki A" sort="Kirsh, Vicki A" uniqKey="Kirsh V" first="Vicki A." last="Kirsh">Vicki A. Kirsh</name><affiliation><nlm:aff id="aff21"></nlm:aff></affiliation><affiliation><nlm:aff id="aff22"></nlm:aff></affiliation></author><author><name sortKey="Linet, Martha S" sort="Linet, Martha S" uniqKey="Linet M" first="Martha S." last="Linet">Martha S. Linet</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Macinnis, Robert J" sort="Macinnis, Robert J" uniqKey="Macinnis R" first="Robert J." last="Macinnis">Robert J. Macinnis</name><affiliation><nlm:aff id="aff18"></nlm:aff></affiliation><affiliation><nlm:aff id="aff19"></nlm:aff></affiliation></author><author><name sortKey="Orsini, Nicola" sort="Orsini, Nicola" uniqKey="Orsini N" first="Nicola" last="Orsini">Nicola Orsini</name><affiliation><nlm:aff id="aff4"></nlm:aff></affiliation></author><author><name sortKey="Park, Yikyung" sort="Park, Yikyung" uniqKey="Park Y" first="Yikyung" last="Park">Yikyung Park</name><affiliation><nlm:aff id="aff23"></nlm:aff></affiliation></author><author><name sortKey="Patel, Alpa V" sort="Patel, Alpa V" uniqKey="Patel A" first="Alpa V." last="Patel">Alpa V. Patel</name><affiliation><nlm:aff id="aff2"></nlm:aff></affiliation></author><author><name sortKey="Purdue, Mark P" sort="Purdue, Mark P" uniqKey="Purdue M" first="Mark P." last="Purdue">Mark P. Purdue</name><affiliation><nlm:aff id="aff24"></nlm:aff></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation><nlm:aff id="aff25"></nlm:aff></affiliation></author><author><name sortKey="Robien, Kimberly" sort="Robien, Kimberly" uniqKey="Robien K" first="Kimberly" last="Robien">Kimberly Robien</name><affiliation><nlm:aff id="aff26"></nlm:aff></affiliation></author><author><name sortKey="Rohan, Thomas" sort="Rohan, Thomas" uniqKey="Rohan T" first="Thomas" last="Rohan">Thomas Rohan</name><affiliation><nlm:aff id="aff27"></nlm:aff></affiliation></author><author><name sortKey="Sandler, Dale P" sort="Sandler, Dale P" uniqKey="Sandler D" first="Dale P." last="Sandler">Dale P. Sandler</name><affiliation><nlm:aff id="aff14"></nlm:aff></affiliation></author><author><name sortKey="Schairer, Catherine" sort="Schairer, Catherine" uniqKey="Schairer C" first="Catherine" last="Schairer">Catherine Schairer</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Schneider, Arthur B" sort="Schneider, Arthur B" uniqKey="Schneider A" first="Arthur B." last="Schneider">Arthur B. Schneider</name><affiliation><nlm:aff id="aff28"></nlm:aff></affiliation></author><author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D." last="Sesso">Howard D. Sesso</name><affiliation><nlm:aff id="aff7"></nlm:aff></affiliation><affiliation><nlm:aff id="aff11"></nlm:aff></affiliation><affiliation><nlm:aff id="aff16"></nlm:aff></affiliation></author><author><name sortKey="Shu, Xiao Ou" sort="Shu, Xiao Ou" uniqKey="Shu X" first="Xiao-Ou" last="Shu">Xiao-Ou Shu</name><affiliation><nlm:aff id="aff29"></nlm:aff></affiliation></author><author><name sortKey="Singh, Pramil N" sort="Singh, Pramil N" uniqKey="Singh P" first="Pramil N." last="Singh">Pramil N. Singh</name><affiliation><nlm:aff id="aff30"></nlm:aff></affiliation></author><author><name sortKey="Van Den Brandt, Piet A" sort="Van Den Brandt, Piet A" uniqKey="Van Den Brandt P" first="Piet A." last="Van Den Brandt">Piet A. Van Den Brandt</name><affiliation><nlm:aff id="aff31"></nlm:aff></affiliation></author><author><name sortKey="Ward, Elizabeth" sort="Ward, Elizabeth" uniqKey="Ward E" first="Elizabeth" last="Ward">Elizabeth Ward</name><affiliation><nlm:aff id="aff32"></nlm:aff></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation><nlm:aff id="aff6"></nlm:aff></affiliation><affiliation><nlm:aff id="aff33"></nlm:aff></affiliation><affiliation><nlm:aff id="aff34"></nlm:aff></affiliation><affiliation><nlm:aff id="aff35"></nlm:aff></affiliation></author><author><name sortKey="White, Emily" sort="White, Emily" uniqKey="White E" first="Emily" last="White">Emily White</name><affiliation><nlm:aff id="aff36"></nlm:aff></affiliation><affiliation><nlm:aff id="aff37"></nlm:aff></affiliation></author><author><name sortKey="Xiang, Yong Bing" sort="Xiang, Yong Bing" uniqKey="Xiang Y" first="Yong-Bing" last="Xiang">Yong-Bing Xiang</name><affiliation><nlm:aff id="aff15"></nlm:aff></affiliation></author><author><name sortKey="Zeleniuch Jacquotte, Anne" sort="Zeleniuch Jacquotte, Anne" uniqKey="Zeleniuch Jacquotte A" first="Anne" last="Zeleniuch-Jacquotte">Anne Zeleniuch-Jacquotte</name><affiliation><nlm:aff id="aff38"></nlm:aff></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation><nlm:aff id="aff29"></nlm:aff></affiliation></author><author><name sortKey="Hartge, Patricia" sort="Hartge, Patricia" uniqKey="Hartge P" first="Patricia" last="Hartge">Patricia Hartge</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Berrington De Gonzalez, Amy" sort="Berrington De Gonzalez, Amy" uniqKey="Berrington De Gonzalez A" first="Amy" last="Berrington De González">Amy Berrington De González</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">Thyroid</title><idno type="ISSN">1050-7256</idno><idno type="eISSN">1557-9077</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><bold><italic>Background:</italic></bold> Greater height and body mass index (BMI) have been associated with an increased risk of thyroid cancer, particularly papillary carcinoma, the most common and least aggressive subtype. Few studies have evaluated these associations in relation to other, more aggressive histologic types or thyroid cancer-specific mortality.</p><p><bold><italic>Methods:</italic></bold> This large pooled analysis of 22 prospective studies (833,176 men and 1,260,871 women) investigated thyroid cancer incidence associated with greater height, BMI at baseline and young adulthood, and adulthood BMI gain (difference between young-adult and baseline BMI), overall and separately by sex and histological subtype using multivariable Cox proportional hazards regression models. Associations with thyroid cancer mortality were investigated in a subset of cohorts (578,922 men and 774,373 women) that contributed cause of death information.</p><p><bold><italic>Results:</italic></bold> During follow-up, 2996 incident thyroid cancers and 104 thyroid cancer deaths were identified. All anthropometric factors were positively associated with thyroid cancer incidence: hazard ratios (HR) [confidence intervals (CIs)] for height (per 5 cm) = 1.07 [1.04–1.10], BMI (per 5 kg/m<sup>2</sup>) = 1.06 [1.02–1.10], waist circumference (per 5 cm) = 1.03 [1.01–1.05], young-adult BMI (per 5 kg/m<sup>2</sup>) = 1.13 [1.02–1.25], and adulthood BMI gain (per 5 kg/m<sup>2</sup>) = 1.07 [1.00–1.15]. Associations for baseline BMI and waist circumference were attenuated after mutual adjustment. Baseline BMI was more strongly associated with risk in men compared with women (<italic>p</italic> = 0.04). Positive associations were observed for papillary, follicular, and anaplastic, but not medullary, thyroid carcinomas. Similar, but stronger, associations were observed for thyroid cancer mortality.</p><p><bold><italic>Conclusion:</italic></bold> The results suggest that greater height and excess adiposity throughout adulthood are associated with higher incidence of most major types of thyroid cancer, including the least common but most aggressive form, anaplastic carcinoma, and higher thyroid cancer mortality. Potential underlying biological mechanisms should be explored in future studies.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Thyroid</journal-id><journal-id journal-id-type="iso-abbrev">Thyroid</journal-id><journal-id journal-id-type="publisher-id">thy</journal-id><journal-title-group><journal-title>Thyroid</journal-title></journal-title-group><issn pub-type="ppub">1050-7256</issn><issn pub-type="epub">1557-9077</issn><publisher><publisher-name>Mary Ann Liebert, Inc.</publisher-name><publisher-loc>140 Huguenot Street, 3rd FloorNew Rochelle, NY 10801USA</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26756356</article-id><article-id pub-id-type="pmc">4754509</article-id><article-id pub-id-type="publisher-id">10.1089/thy.2015.0319</article-id><article-id pub-id-type="doi">10.1089/thy.2015.0319</article-id><article-categories><subj-group subj-group-type="heading"><subject>Epidemiology</subject></subj-group></article-categories><title-group><article-title>Anthropometric Factors and Thyroid Cancer Risk by Histological Subtype: Pooled Analysis of 22 Prospective Studies</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Kitahara</surname><given-names>Cari M.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>McCullough</surname><given-names>Marjorie L.</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Franceschi</surname><given-names>Silvia</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Rinaldi</surname><given-names>Sabina</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Wolk</surname><given-names>Alicja</given-names></name><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Neta</surname><given-names>Gila</given-names></name><xref ref-type="aff" rid="aff5"><sup>5</sup></xref></contrib><contrib contrib-type="author"><name><surname>Olov Adami</surname><given-names>Hans</given-names></name><xref ref-type="aff" rid="aff6"><sup>6,</sup></xref><xref ref-type="aff" rid="aff7"><sup>7</sup></xref></contrib><contrib contrib-type="author"><name><surname>Anderson</surname><given-names>Kristin</given-names></name><xref ref-type="aff" rid="aff8"><sup>8,</sup></xref><xref ref-type="aff" rid="aff9"><sup>9</sup></xref></contrib><contrib contrib-type="author"><name><surname>Andreotti</surname><given-names>Gabriella</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Beane Freeman</surname><given-names>Laura E.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Bernstein</surname><given-names>Leslie</given-names></name><xref ref-type="aff" rid="aff10"><sup>10</sup></xref></contrib><contrib contrib-type="author"><name><surname>Buring</surname><given-names>Julie E.</given-names></name><xref ref-type="aff" rid="aff7"><sup>7,</sup></xref><xref ref-type="aff" rid="aff11"><sup>11</sup></xref></contrib><contrib contrib-type="author"><name><surname>Clavel-Chapelon</surname><given-names>Francoise</given-names></name><xref ref-type="aff" rid="aff12"><sup>12</sup></xref></contrib><contrib contrib-type="author"><name><surname>De Roo</surname><given-names>Lisa A.</given-names></name><xref ref-type="aff" rid="aff13"><sup>13,</sup></xref><xref ref-type="aff" rid="aff14"><sup>14</sup></xref></contrib><contrib contrib-type="author"><name><surname>Gao</surname><given-names>Yu-Tang</given-names></name><xref ref-type="aff" rid="aff15"><sup>15</sup></xref></contrib><contrib contrib-type="author"><name><surname>Gaziano</surname><given-names>J. Michael</given-names></name><xref ref-type="aff" rid="aff11"><sup>11,</sup></xref><xref ref-type="aff" rid="aff16"><sup>16,</sup></xref><xref ref-type="aff" rid="aff17"><sup>17</sup></xref></contrib><contrib contrib-type="author"><name><surname>Giles</surname><given-names>Graham G.</given-names></name><xref ref-type="aff" rid="aff18"><sup>18,</sup></xref><xref ref-type="aff" rid="aff19"><sup>19</sup></xref></contrib><contrib contrib-type="author"><name><surname>Håkansson</surname><given-names>Niclas</given-names></name><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Horn-Ross</surname><given-names>Pamela L.</given-names></name><xref ref-type="aff" rid="aff20"><sup>20</sup></xref></contrib><contrib contrib-type="author"><name><surname>Kirsh</surname><given-names>Vicki A.</given-names></name><xref ref-type="aff" rid="aff21"><sup>21,</sup></xref><xref ref-type="aff" rid="aff22"><sup>22</sup></xref></contrib><contrib contrib-type="author"><name><surname>Linet</surname><given-names>Martha S.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>MacInnis</surname><given-names>Robert J.</given-names></name><xref ref-type="aff" rid="aff18"><sup>18,</sup></xref><xref ref-type="aff" rid="aff19"><sup>19</sup></xref></contrib><contrib contrib-type="author"><name><surname>Orsini</surname><given-names>Nicola</given-names></name><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Park</surname><given-names>Yikyung</given-names></name><xref ref-type="aff" rid="aff23"><sup>23</sup></xref></contrib><contrib contrib-type="author"><name><surname>Patel</surname><given-names>Alpa V.</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Purdue</surname><given-names>Mark P.</given-names></name><xref ref-type="aff" rid="aff24"><sup>24</sup></xref></contrib><contrib contrib-type="author"><name><surname>Riboli</surname><given-names>Elio</given-names></name><xref ref-type="aff" rid="aff25"><sup>25</sup></xref></contrib><contrib contrib-type="author"><name><surname>Robien</surname><given-names>Kimberly</given-names></name><xref ref-type="aff" rid="aff26"><sup>26</sup></xref></contrib><contrib contrib-type="author"><name><surname>Rohan</surname><given-names>Thomas</given-names></name><xref ref-type="aff" rid="aff27"><sup>27</sup></xref></contrib><contrib contrib-type="author"><name><surname>Sandler</surname><given-names>Dale P.</given-names></name><xref ref-type="aff" rid="aff14"><sup>14</sup></xref></contrib><contrib contrib-type="author"><name><surname>Schairer</surname><given-names>Catherine</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Schneider</surname><given-names>Arthur B.</given-names></name><xref ref-type="aff" rid="aff28"><sup>28</sup></xref></contrib><contrib contrib-type="author"><name><surname>Sesso</surname><given-names>Howard D.</given-names></name><xref ref-type="aff" rid="aff7"><sup>7,</sup></xref><xref ref-type="aff" rid="aff11"><sup>11,</sup></xref><xref ref-type="aff" rid="aff16"><sup>16</sup></xref></contrib><contrib contrib-type="author"><name><surname>Shu</surname><given-names>Xiao-Ou</given-names></name><xref ref-type="aff" rid="aff29"><sup>29</sup></xref></contrib><contrib contrib-type="author"><name><surname>Singh</surname><given-names>Pramil N.</given-names></name><xref ref-type="aff" rid="aff30"><sup>30</sup></xref></contrib><contrib contrib-type="author"><name><surname>van den Brandt</surname><given-names>Piet A.</given-names></name><xref ref-type="aff" rid="aff31"><sup>31</sup></xref></contrib><contrib contrib-type="author"><name><surname>Ward</surname><given-names>Elizabeth</given-names></name><xref ref-type="aff" rid="aff32"><sup>32</sup></xref></contrib><contrib contrib-type="author"><name><surname>Weiderpass</surname><given-names>Elisabete</given-names></name><xref ref-type="aff" rid="aff6"><sup>6,</sup></xref><xref ref-type="aff" rid="aff33"><sup>33,</sup></xref><xref ref-type="aff" rid="aff34"><sup>34,</sup></xref><xref ref-type="aff" rid="aff35"><sup>35</sup></xref></contrib><contrib contrib-type="author"><name><surname>White</surname><given-names>Emily</given-names></name><xref ref-type="aff" rid="aff36"><sup>36,</sup></xref><xref ref-type="aff" rid="aff37"><sup>37</sup></xref></contrib><contrib contrib-type="author"><name><surname>Xiang</surname><given-names>Yong-Bing</given-names></name><xref ref-type="aff" rid="aff15"><sup>15</sup></xref></contrib><contrib contrib-type="author"><name><surname>Zeleniuch-Jacquotte</surname><given-names>Anne</given-names></name><xref ref-type="aff" rid="aff38"><sup>38</sup></xref></contrib><contrib contrib-type="author"><name><surname>Zheng</surname><given-names>Wei</given-names></name><xref ref-type="aff" rid="aff29"><sup>29</sup></xref></contrib><contrib contrib-type="author"><name><surname>Hartge</surname><given-names>Patricia</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Berrington de González</surname><given-names>Amy</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><aff id="aff1"><label><sup>1</sup></label>Division of Cancer Epidemiology and Genetics;<institution>National Cancer Institute</institution>, Rockville, Maryland.</aff><aff id="aff2"><label><sup>2</sup></label>Epidemiology Research Program,<institution>American Cancer Society</institution>, Atlanta,<country>Georgia</country>.</aff><aff id="aff3"><label><sup>3</sup></label><institution>International Agency for Research on Cancer</institution>, Lyon,<country>France</country>.</aff><aff id="aff4"><label><sup>4</sup></label>Division of Nutritional Epidemiology, Institute of Environmental Medicine;<institution>Karolinska Institutet</institution>, Stockholm,<country>Sweden</country>.</aff><aff id="aff5"><label><sup>5</sup></label>Division of Cancer Control and Population Sciences;<institution>National Cancer Institute</institution>, Rockville, Maryland.</aff><aff id="aff6"><label><sup>6</sup></label>Department of Medical Epidemiology and Biostatistics;<institution>Karolinska Institutet</institution>, Stockholm,<country>Sweden</country>.</aff><aff id="aff7"><label><sup>7</sup></label>Department of Epidemiology,<institution>Harvard School of Public Health</institution>, Boston, Massachusetts.</aff><aff id="aff8"><label><sup>8</sup></label>Division of Epidemiology and Community Health, School of Public Health;<institution>University of Minnesota</institution>, Minneapolis, Minnesota.</aff><aff id="aff9"><label><sup>9</sup></label>Masonic Cancer Center;<institution>University of Minnesota</institution>, Minneapolis, Minnesota.</aff><aff id="aff10"><label><sup>10</sup></label>Division of Cancer Etiology, Department of Population Sciences,<institution>Beckman Research Institute</institution>, City of Hope, Duarte, California.</aff><aff id="aff11"><label><sup>11</sup></label>Division of Preventive Medicine, Department of Medicine;<institution>Brigham and Women's Hospital</institution>, Boston, Massachusetts.</aff><aff id="aff12"><label><sup>12</sup></label>Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Villejuif,<institution>France Paris South University</institution>, UMRS Inserm 1018 Team 9, Villejuif,<country>France</country>.</aff><aff id="aff13"><label><sup>13</sup></label>Department of Global Public Health and Primary Care,<institution>University of Bergen</institution>, Bergen,<country>Norway</country>.</aff><aff id="aff14"><label><sup>14</sup></label>Epidemiology Branch,<institution>National Institute of Environmental Health Sciences</institution>, Research Triangle Park, North Carolina.</aff><aff id="aff15"><label><sup>15</sup></label>Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital,<institution>Shanghai Jiaotong University School of Medicine</institution>, Shanghai,<country>China</country>.</aff><aff id="aff16"><label><sup>16</sup></label>Division of Aging;<institution>Brigham and Women's Hospital</institution>, Boston, Massachusetts.</aff><aff id="aff17"><label><sup>17</sup></label>Massachusetts Veteran's Epidemiology, Research, and Information Center,<institution>Geriatric Research Education and Clinical Center</institution>, VA Boston Healthcare System, Boston, Massachusetts.</aff><aff id="aff18"><label><sup>18</sup></label>Cancer Epidemiology Centre,<institution>Cancer Council Victoria</institution>, Melbourne,<country>Australia</country>.</aff><aff id="aff19"><label><sup>19</sup></label>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health,<institution>The University of Melbourne</institution>, Carlton,<country>Australia</country>.</aff><aff id="aff20"><label><sup>20</sup></label><institution>Cancer Prevention Institute of California</institution>, Fremont, California.</aff><aff id="aff21"><label><sup>21</sup></label>Prevention and Cancer Control,<institution>Cancer Care Ontario</institution>, Toronto,<country>Canada</country>.</aff><aff id="aff22"><label><sup>22</sup></label>Dalla Lana School of Public Health,<institution>University of Toronto</institution>, Toronto,<country>Canada</country>.</aff><aff id="aff23"><label><sup>23</sup></label>Division of Public Health Sciences,<institution>Washington University School of Medicine in St. Louis</institution>, St. Louis, Missouri.</aff><aff id="aff24"><label><sup>24</sup></label><institution>Ontario Institute for Cancer Research</institution>, Toronto,<country>Canada</country>.</aff><aff id="aff25"><label><sup>25</sup></label>Imperial School of Public Health,<institution>Imperial College London</institution>, London,<country>United Kingdom</country>.</aff><aff id="aff26"><label><sup>26</sup></label>Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health,<institution>George Washington University</institution>, Washington, DC.</aff><aff id="aff27"><label><sup>27</sup></label>Department of Epidemiology and Population Health,<institution>Albert Einstein College of Medicine</institution>, Bronx, New York.</aff><aff id="aff28"><label><sup>28</sup></label>Section of Endocrinology, Diabetes and Metabolism,<institution>University of Illinois at Chicago</institution>, Chicago, Illinois.</aff><aff id="aff29"><label><sup>29</sup></label>Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center,<institution>Vanderbilt University School of Medicine</institution>, Nashville, Tennessee.</aff><aff id="aff30"><label><sup>30</sup></label>Center for Health Research, School of Public Health,<institution>Loma Linda University</institution>, Loma Linda, California.</aff><aff id="aff31"><label><sup>31</sup></label>Department of Epidemiology, GROW School for Oncology and Developmental Biology,<institution>Maastricht University</institution>, Maastricht,<country>Netherlands</country>.</aff><aff id="aff32"><label><sup>32</sup></label>Intramural Research,<institution>American Cancer Society</institution>, Atlanta,<country>Georgia</country>.</aff><aff id="aff33"><label><sup>33</sup></label>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø,<institution>The Arctic University of Norway</institution>, Tromsø,<country>Norway</country>.</aff><aff id="aff34"><label><sup>34</sup></label>Department of Research, Cancer Registry of Norway,<institution>Institute of Population-Based Cancer Research</institution>, Oslo,<country>Norway</country>.</aff><aff id="aff35"><label><sup>35</sup></label>Genetic Epidemiology Group,<institution>Folkälsan Research Center</institution>, Helsinki,<country>Finland</country>.</aff><aff id="aff36"><label><sup>36</sup></label>Public Health Services Division,<institution>Fred Hutchinson Cancer Research Center</institution>, Seattle, Washington.</aff><aff id="aff37"><label><sup>37</sup></label>Department of Epidemiology,<institution>University of Washington</institution>, Seattle, Washington.</aff><aff id="aff38"><label><sup>38</sup></label>Division of Epidemiology, Department of Population Health and NYU Cancer Institute,<institution>NYU School of Medicine</institution>, New York, New York.</aff></contrib-group><author-notes><corresp><addr-line>Address correspondence to:</addr-line><addr-line><italic>Cari Meinhold Kitahara, PhD, MHS</italic></addr-line><addr-line><italic>Division of Cancer Epidemiology and Genetics</italic></addr-line><addr-line><italic>9609 Medical Center Drive, Rm. 7E-536</italic></addr-line><addr-line><italic>Bethesda, MD 20892-9774</italic></addr-line><italic>E-mail:</italic><email xlink:href="mailto:kitaharac@mail.nih.gov">kitaharac@mail.nih.gov</email></corresp></author-notes><pub-date pub-type="ppub"><day>01</day><month>2</month><year>2016</year><pmc-comment>string-date: February 2016</pmc-comment>
</pub-date><volume>26</volume><issue>2</issue><fpage>306</fpage><lpage>318</lpage><permissions><copyright-statement>Copyright 2016, Mary Ann Liebert, Inc.</copyright-statement><copyright-year>2016</copyright-year></permissions><self-uri content-type="pdf" xlink:type="simple" xlink:href="thy.2015.0319.pdf"></self-uri><abstract><p><bold><italic>Background:</italic></bold> Greater height and body mass index (BMI) have been associated with an increased risk of thyroid cancer, particularly papillary carcinoma, the most common and least aggressive subtype. Few studies have evaluated these associations in relation to other, more aggressive histologic types or thyroid cancer-specific mortality.</p><p><bold><italic>Methods:</italic></bold> This large pooled analysis of 22 prospective studies (833,176 men and 1,260,871 women) investigated thyroid cancer incidence associated with greater height, BMI at baseline and young adulthood, and adulthood BMI gain (difference between young-adult and baseline BMI), overall and separately by sex and histological subtype using multivariable Cox proportional hazards regression models. Associations with thyroid cancer mortality were investigated in a subset of cohorts (578,922 men and 774,373 women) that contributed cause of death information.</p><p><bold><italic>Results:</italic></bold> During follow-up, 2996 incident thyroid cancers and 104 thyroid cancer deaths were identified. All anthropometric factors were positively associated with thyroid cancer incidence: hazard ratios (HR) [confidence intervals (CIs)] for height (per 5 cm) = 1.07 [1.04–1.10], BMI (per 5 kg/m<sup>2</sup>) = 1.06 [1.02–1.10], waist circumference (per 5 cm) = 1.03 [1.01–1.05], young-adult BMI (per 5 kg/m<sup>2</sup>) = 1.13 [1.02–1.25], and adulthood BMI gain (per 5 kg/m<sup>2</sup>) = 1.07 [1.00–1.15]. Associations for baseline BMI and waist circumference were attenuated after mutual adjustment. Baseline BMI was more strongly associated with risk in men compared with women (<italic>p</italic> = 0.04). Positive associations were observed for papillary, follicular, and anaplastic, but not medullary, thyroid carcinomas. Similar, but stronger, associations were observed for thyroid cancer mortality.</p><p><bold><italic>Conclusion:</italic></bold> The results suggest that greater height and excess adiposity throughout adulthood are associated with higher incidence of most major types of thyroid cancer, including the least common but most aggressive form, anaplastic carcinoma, and higher thyroid cancer mortality. Potential underlying biological mechanisms should be explored in future studies.</p></abstract><counts><table-count count="3"></table-count><ref-count count="63"></ref-count><page-count count="13"></page-count></counts></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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