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A Method to Determine the Transfer of Mycotoxins from Materials to Air

Identifieur interne : 002C82 ( PascalFrancis/Curation ); précédent : 002C81; suivant : 002C83

A Method to Determine the Transfer of Mycotoxins from Materials to Air

Auteurs : Stephane Moularat [France] ; Enric Robine [France]

Source :

RBID : Pascal:08-0393898

Descripteurs français

English descriptors

Abstract

The aim of this work was to propose a new methodological approach to enable the measurement of three airborne mycotoxins and thus determine directly the rate of production and physical characteristics of these aerosols. A method enabling the measurement of three major mycotoxins in indoor air (sterigmatocystin (ST), deoxynivalenol (DON), and ochratoxin A (OA)) was thus optimized. This assay method was able to identify and quantify these mycotoxins at respective concentrations of 30 μg/L (n = 30, σ/m = 3.9%), 20 μg/L (n = 10, σ/m = 5.5%), and 20 μg/L (n = 10, σ/m = 7.6%). Using this analytical technique and a rotary cup collection system validated elsewhere, measurement of the concentrations of three airborne mycotoxins was made possible with a theoretical limit of quantification (LOQ) of 60 pg/m3 of air. Study of the transfer of mycotoxins from a substrate to the air made it possible to demonstrate, firstly, that the quantity of aerosolized mycotoxins was not proportional to that present on the moldy materials, and secondly that mycotoxins can be transported by aerosols in the alveolar fraction. We determined, under these conditions, a rate of production of ST aerosols.
pA  
A01 01  2    @0 1863-0650
A05       @2 36
A06       @2 7
A08 01  1  ENG  @1 A Method to Determine the Transfer of Mycotoxins from Materials to Air
A09 01  1  ENG  @1 Bioaerosol Research
A11 01  1    @1 MOULARAT (Stephane)
A11 02  1    @1 ROBINE (Enric)
A12 01  1    @1 GRINSHPUN (Sergey A.) @9 limin.
A12 02  1    @1 AGRANOVSKI (Igor E.) @9 limin.
A14 01      @1 Laboratoire de Microbiologie des Environnements Intérieurs, Centre Scientifique et Technique du Bâtiment @2 Champs sur Marne @3 FRA @Z 1 aut. @Z 2 aut.
A15 01      @1 Department of Environmental Health, University of Cincinnati @2 Cincinnati, Ohio 45267-0056 @3 USA @Z 1 aut.
A15 02      @1 Environmental Engineering, Griffith School of Engineering, Griffith University @2 Brisbane, 4111, QLD @3 AUS @Z 2 aut.
A20       @1 578-583
A21       @1 2008
A23 01      @0 ENG
A43 01      @1 INIST @2 16925 @5 354000196037610050
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
A45       @0 33 ref.
A47 01  1    @0 08-0393898
A60       @1 P
A61       @0 A
A64 01  2    @0 Clean. Soil, air, water
A66 01      @0 DEU
C01 01    ENG  @0 The aim of this work was to propose a new methodological approach to enable the measurement of three airborne mycotoxins and thus determine directly the rate of production and physical characteristics of these aerosols. A method enabling the measurement of three major mycotoxins in indoor air (sterigmatocystin (ST), deoxynivalenol (DON), and ochratoxin A (OA)) was thus optimized. This assay method was able to identify and quantify these mycotoxins at respective concentrations of 30 μg/L (n = 30, σ/m = 3.9%), 20 μg/L (n = 10, σ/m = 5.5%), and 20 μg/L (n = 10, σ/m = 7.6%). Using this analytical technique and a rotary cup collection system validated elsewhere, measurement of the concentrations of three airborne mycotoxins was made possible with a theoretical limit of quantification (LOQ) of 60 pg/m3 of air. Study of the transfer of mycotoxins from a substrate to the air made it possible to demonstrate, firstly, that the quantity of aerosolized mycotoxins was not proportional to that present on the moldy materials, and secondly that mycotoxins can be transported by aerosols in the alveolar fraction. We determined, under these conditions, a rate of production of ST aerosols.
C02 01  2    @0 001E01N01
C02 02  2    @0 226A01
C03 01  2  FRE  @0 Matériau @5 01
C03 01  2  ENG  @0 materials @5 01
C03 02  2  FRE  @0 Air @5 02
C03 02  2  ENG  @0 air @5 02
C03 03  2  FRE  @0 Aérosol @5 03
C03 03  2  ENG  @0 aerosols @5 03
C03 03  2  SPA  @0 Aerosol @5 03
C03 04  2  FRE  @0 Concentration @5 04
C03 04  2  ENG  @0 concentration @5 04
C03 04  2  SPA  @0 Concentración @5 04
C03 05  2  FRE  @0 Collection @5 05
C03 05  2  ENG  @0 collections @5 05
C03 05  2  SPA  @0 Colección @5 05
C03 06  2  FRE  @0 Substrat @5 06
C03 06  2  ENG  @0 substrates @5 06
C03 07  2  FRE  @0 Transport @5 07
C03 07  2  ENG  @0 transport @5 07
C03 07  2  SPA  @0 Transporte @5 07
N21       @1 252
N44 01      @1 OTO
N82       @1 OTO

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Pascal:08-0393898

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