Sol-gel matrices for controlled release : from macro to nano using emulsion polymerisation
Identifieur interne :
002C01 ( PascalFrancis/Curation );
précédent :
002C00;
suivant :
002C02
Sol-gel matrices for controlled release : from macro to nano using emulsion polymerisation
Auteurs : Christophe J. Barbe [
Australie] ;
LINGGEN KONG [
Australie] ;
Kim S. Finnie [
Australie] ;
Sandrine Calleja [
Australie] ;
Johnv. Hanna [
Australie] ;
Elizabeth Drabarek [
Australie] ;
David T. Cassidy [
Australie] ;
Mark G. Blackford [
Australie]
Source :
-
Journal of sol-gel science and technology [ 0928-0707 ] ; 2008.
RBID : Pascal:08-0325289
Descripteurs français
English descriptors
Abstract
By combining sol-gel technology with emulsion chemistry, it is possible to produce spherical particles with a designed microstructure based on a judicious choice of solvent/surfactant and sol-gel reaction parameters. When an active molecule is located in the aqueous droplet of a water-in-oil (W/O) emulsion, encapsulation occurs as the silicon precursors polymerise to build an oxide cage around the active species. By changing the solvent-surfactant combination, the particle size can be varied from 10 nm to 100 μm. The size of the particles is controlled by the size of the emulsion droplet, which acts as a nano-reactor for the sol-gel reaction. The release profiles can be tailored, independently of the particle size, by controlling the internal structure of the particles: pore volume, pore size, tortuosity, and surface chemistry (e.g. by introduction of trialkoxysilane). This can be easily achieved by controlling sol-gel processing parameters such as the water-to-alkoxide ratio, pH, alkoxide concentration, ageing, drying time and temperature.
pA |
A01 | 01 | 1 | | @0 0928-0707 |
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A03 | | 1 | | @0 J. sol-gel sci. technol. |
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A05 | | | | @2 46 |
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A06 | | | | @2 3 |
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A08 | 01 | 1 | ENG | @1 Sol-gel matrices for controlled release : from macro to nano using emulsion polymerisation |
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A09 | 01 | 1 | ENG | @1 14th International Sol-Gel Conference, Part I |
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A11 | 01 | 1 | | @1 BARBE (Christophe J.) |
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A11 | 02 | 1 | | @1 LINGGEN KONG |
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A11 | 03 | 1 | | @1 FINNIE (Kim S.) |
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A11 | 04 | 1 | | @1 CALLEJA (Sandrine) |
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A11 | 05 | 1 | | @1 HANNA (Johnv.) |
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A11 | 06 | 1 | | @1 DRABAREK (Elizabeth) |
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A11 | 07 | 1 | | @1 CASSIDY (David T.) |
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A11 | 08 | 1 | | @1 BLACKFORD (Mark G.) |
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A12 | 01 | 1 | | @1 WONG CHI MAN (Michel) @9 ed. |
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A12 | 02 | 1 | | @1 VIOUX (André) @9 ed. |
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A14 | 01 | | | @1 Ceramisphere Pty Ltd @2 Menai, NSW 2234 @3 AUS @Z 1 aut. @Z 2 aut. @Z 3 aut. |
---|
A14 | 02 | | | @1 Institute of Materials Engineering, Australian Nuclear Science and Technology Organisation @2 Menai, NSW 2234 @3 AUS @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut. @Z 8 aut. |
---|
A15 | 01 | | | @1 Institut Charles Gerhardt @2 Montpellier @3 FRA @Z 1 aut. @Z 2 aut. |
---|
A20 | | | | @1 393-409 |
---|
A21 | | | | @1 2008 |
---|
A23 | 01 | | | @0 ENG |
---|
A43 | 01 | | | @1 INIST @2 26574 @5 354000197964580160 |
---|
A44 | | | | @0 0000 @1 © 2008 INIST-CNRS. All rights reserved. |
---|
A45 | | | | @0 35 ref. |
---|
A47 | 01 | 1 | | @0 08-0325289 |
---|
A60 | | | | @1 P @2 C |
---|
A61 | | | | @0 A |
---|
A64 | 01 | 1 | | @0 Journal of sol-gel science and technology |
---|
A66 | 01 | | | @0 DEU |
---|
C01 | 01 | | ENG | @0 By combining sol-gel technology with emulsion chemistry, it is possible to produce spherical particles with a designed microstructure based on a judicious choice of solvent/surfactant and sol-gel reaction parameters. When an active molecule is located in the aqueous droplet of a water-in-oil (W/O) emulsion, encapsulation occurs as the silicon precursors polymerise to build an oxide cage around the active species. By changing the solvent-surfactant combination, the particle size can be varied from 10 nm to 100 μm. The size of the particles is controlled by the size of the emulsion droplet, which acts as a nano-reactor for the sol-gel reaction. The release profiles can be tailored, independently of the particle size, by controlling the internal structure of the particles: pore volume, pore size, tortuosity, and surface chemistry (e.g. by introduction of trialkoxysilane). This can be easily achieved by controlling sol-gel processing parameters such as the water-to-alkoxide ratio, pH, alkoxide concentration, ageing, drying time and temperature. |
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C02 | 01 | X | | @0 001C01J05 |
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C02 | 02 | X | | @0 001C01J04 |
---|
C02 | 03 | X | | @0 001C01J02 |
---|
C02 | 04 | X | | @0 002B02 |
---|
C03 | 01 | X | FRE | @0 Procédé sol gel @5 01 |
---|
C03 | 01 | X | ENG | @0 Sol gel process @5 01 |
---|
C03 | 01 | X | SPA | @0 Procedimiento sol gel @5 01 |
---|
C03 | 02 | X | FRE | @0 Libération @5 02 |
---|
C03 | 02 | X | ENG | @0 Release @5 02 |
---|
C03 | 02 | X | SPA | @0 Liberación @5 02 |
---|
C03 | 03 | X | FRE | @0 Emulsion @5 03 |
---|
C03 | 03 | X | ENG | @0 Emulsion @5 03 |
---|
C03 | 03 | X | SPA | @0 Emulsión @5 03 |
---|
C03 | 04 | X | FRE | @0 Médicament @5 04 |
---|
C03 | 04 | X | ENG | @0 Drug @5 04 |
---|
C03 | 04 | X | SPA | @0 Medicamento @5 04 |
---|
C03 | 05 | X | FRE | @0 Nanoparticule @5 05 |
---|
C03 | 05 | X | ENG | @0 Nanoparticle @5 05 |
---|
C03 | 05 | X | SPA | @0 Nanopartícula @5 05 |
---|
C03 | 06 | X | FRE | @0 Particule @2 FX @5 06 |
---|
C03 | 06 | X | ENG | @0 Particle @2 FX @5 06 |
---|
C03 | 06 | X | SPA | @0 Partícula @2 FX @5 06 |
---|
C03 | 07 | X | FRE | @0 Encapsulation @5 07 |
---|
C03 | 07 | X | ENG | @0 Encapsulation @5 07 |
---|
C03 | 07 | X | SPA | @0 Encapsulación @5 07 |
---|
C03 | 08 | 3 | FRE | @0 Système administration médicament @5 08 |
---|
C03 | 08 | 3 | ENG | @0 Drug delivery systems @5 08 |
---|
N21 | | | | @1 203 |
---|
|
pR |
A30 | 01 | 1 | ENG | @1 International Conference Sol-Gel 2007 @2 14 @3 Montpellier FRA @4 2007-09-02 |
---|
|
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Le document en format XML
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</affiliation>
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<author><name sortKey="Calleja, Sandrine" sort="Calleja, Sandrine" uniqKey="Calleja S" first="Sandrine" last="Calleja">Sandrine Calleja</name>
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<author><name sortKey="Hanna, Johnv" sort="Hanna, Johnv" uniqKey="Hanna J" first="Johnv." last="Hanna">Johnv. Hanna</name>
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<author><name sortKey="Drabarek, Elizabeth" sort="Drabarek, Elizabeth" uniqKey="Drabarek E" first="Elizabeth" last="Drabarek">Elizabeth Drabarek</name>
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<s2>Menai, NSW 2234</s2>
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<author><name sortKey="Cassidy, David T" sort="Cassidy, David T" uniqKey="Cassidy D" first="David T." last="Cassidy">David T. Cassidy</name>
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<s2>Menai, NSW 2234</s2>
<s3>AUS</s3>
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<author><name sortKey="Blackford, Mark G" sort="Blackford, Mark G" uniqKey="Blackford M" first="Mark G." last="Blackford">Mark G. Blackford</name>
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<series><title level="j" type="main">Journal of sol-gel science and technology</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Drug</term>
<term>Drug delivery systems</term>
<term>Emulsion</term>
<term>Encapsulation</term>
<term>Nanoparticle</term>
<term>Particle</term>
<term>Release</term>
<term>Sol gel process</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Procédé sol gel</term>
<term>Libération</term>
<term>Emulsion</term>
<term>Médicament</term>
<term>Nanoparticule</term>
<term>Particule</term>
<term>Encapsulation</term>
<term>Système administration médicament</term>
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<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Médicament</term>
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<front><div type="abstract" xml:lang="en">By combining sol-gel technology with emulsion chemistry, it is possible to produce spherical particles with a designed microstructure based on a judicious choice of solvent/surfactant and sol-gel reaction parameters. When an active molecule is located in the aqueous droplet of a water-in-oil (W/O) emulsion, encapsulation occurs as the silicon precursors polymerise to build an oxide cage around the active species. By changing the solvent-surfactant combination, the particle size can be varied from 10 nm to 100 μm. The size of the particles is controlled by the size of the emulsion droplet, which acts as a nano-reactor for the sol-gel reaction. The release profiles can be tailored, independently of the particle size, by controlling the internal structure of the particles: pore volume, pore size, tortuosity, and surface chemistry (e.g. by introduction of trialkoxysilane). This can be easily achieved by controlling sol-gel processing parameters such as the water-to-alkoxide ratio, pH, alkoxide concentration, ageing, drying time and temperature.</div>
</front>
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<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0928-0707</s0>
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<fA11 i1="01" i2="1"><s1>BARBE (Christophe J.)</s1>
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<fA11 i1="02" i2="1"><s1>LINGGEN KONG</s1>
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<fA11 i1="03" i2="1"><s1>FINNIE (Kim S.)</s1>
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<fA11 i1="04" i2="1"><s1>CALLEJA (Sandrine)</s1>
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<fA11 i1="07" i2="1"><s1>CASSIDY (David T.)</s1>
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<fA11 i1="08" i2="1"><s1>BLACKFORD (Mark G.)</s1>
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<fA12 i1="01" i2="1"><s1>WONG CHI MAN (Michel)</s1>
<s9>ed.</s9>
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<fA12 i1="02" i2="1"><s1>VIOUX (André)</s1>
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<fA14 i1="01"><s1>Ceramisphere Pty Ltd</s1>
<s2>Menai, NSW 2234</s2>
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<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
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<s2>Menai, NSW 2234</s2>
<s3>AUS</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
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<fC01 i1="01" l="ENG"><s0>By combining sol-gel technology with emulsion chemistry, it is possible to produce spherical particles with a designed microstructure based on a judicious choice of solvent/surfactant and sol-gel reaction parameters. When an active molecule is located in the aqueous droplet of a water-in-oil (W/O) emulsion, encapsulation occurs as the silicon precursors polymerise to build an oxide cage around the active species. By changing the solvent-surfactant combination, the particle size can be varied from 10 nm to 100 μm. The size of the particles is controlled by the size of the emulsion droplet, which acts as a nano-reactor for the sol-gel reaction. The release profiles can be tailored, independently of the particle size, by controlling the internal structure of the particles: pore volume, pore size, tortuosity, and surface chemistry (e.g. by introduction of trialkoxysilane). This can be easily achieved by controlling sol-gel processing parameters such as the water-to-alkoxide ratio, pH, alkoxide concentration, ageing, drying time and temperature.</s0>
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<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Libération</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Release</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Liberación</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Emulsion</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Emulsion</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Emulsión</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Médicament</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Drug</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Medicamento</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Nanoparticule</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Nanoparticle</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Nanopartícula</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Particule</s0>
<s2>FX</s2>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Particle</s0>
<s2>FX</s2>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Partícula</s0>
<s2>FX</s2>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Encapsulation</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Encapsulation</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Encapsulación</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="3" l="FRE"><s0>Système administration médicament</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="3" l="ENG"><s0>Drug delivery systems</s0>
<s5>08</s5>
</fC03>
<fN21><s1>203</s1>
</fN21>
</pA>
<pR><fA30 i1="01" i2="1" l="ENG"><s1>International Conference Sol-Gel 2007</s1>
<s2>14</s2>
<s3>Montpellier FRA</s3>
<s4>2007-09-02</s4>
</fA30>
</pR>
</standard>
</inist>
</record>
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