Coenzyme Q10 deficiency in septic shock patients
Identifieur interne : 000C00 ( Ncbi/Merge ); précédent : 000B99; suivant : 000C01Coenzyme Q10 deficiency in septic shock patients
Auteurs : Laurent Dupic [France] ; Olivier Huet [Australie, France] ; Jacques Duranteau [France]Source :
- Critical Care [ 1364-8535 ] ; 2011.
Abstract
Donnino and colleagues provide new insights into the field of oxidative stress and mitochondrial dysfunction during septic shock. These authors suggest a coenzyme Q10 (CoQ10) deficiency in patients with septic shock. Larger prospective observational trials measuring CoQ10 in patients with septic shock are required to confirm the possibility of CoQ10 depletion. This study is a new step toward a study testing CoQ10 as a potential therapeutic agent for patients with septic shock.
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DOI: 10.1186/cc10429
PubMed: 22011617
PubMed Central: 3334745
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Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Réanimation pédiatrique, Université Paris Descartes, 149, rue de Sèvres, 75015 Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Réanimation pédiatrique, Université Paris Descartes, 149, rue de Sèvres, 75015 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris-Descartes</orgName></affiliation></author><author><name sortKey="Huet, Olivier" sort="Huet, Olivier" uniqKey="Huet O" first="Olivier" last="Huet">Olivier Huet</name><affiliation wicri:level="1"><nlm:aff id="I2">Vascular Pharmacology Laboratory, BakerIDI Heart and Diabetes Institute, 75 Commercial Road, 3004 Melbourne, VIC, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Vascular Pharmacology Laboratory, BakerIDI Heart and Diabetes Institute, 75 Commercial Road, 3004 Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I3">Assistance Publique - Hôpitaux de Paris, Hôpital Bicêtre, Département d'Anesthésie-Réanimation, EA 3509 Université Paris Sud XI, France F-94275, Le Kremlin-Bicêtre, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris, Hôpital Bicêtre, Département d'Anesthésie-Réanimation, EA 3509 Université Paris Sud XI, France F-94275, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>94275, Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>94275, Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Duranteau, Jacques" sort="Duranteau, Jacques" uniqKey="Duranteau J" first="Jacques" last="Duranteau">Jacques Duranteau</name><affiliation wicri:level="1"><nlm:aff id="I3">Assistance Publique - Hôpitaux de Paris, Hôpital Bicêtre, Département d'Anesthésie-Réanimation, EA 3509 Université Paris Sud XI, France F-94275, Le Kremlin-Bicêtre, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris, Hôpital Bicêtre, Département d'Anesthésie-Réanimation, EA 3509 Université Paris Sud XI, France F-94275, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>94275, Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>94275, Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author></analytic><series><title level="j">Critical Care</title><idno type="ISSN">1364-8535</idno><idno type="eISSN">1466-609X</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Donnino and colleagues provide new insights into the field of oxidative stress and mitochondrial dysfunction during septic shock. These authors suggest a coenzyme Q<sub>10 </sub>(CoQ<sub>10</sub>) deficiency in patients with septic shock. Larger prospective observational trials measuring CoQ<sub>10 </sub>in patients with septic shock are required to confirm the possibility of CoQ<sub>10 </sub>depletion. This study is a new step toward a study testing CoQ<sub>10 </sub>as a potential therapeutic agent for patients with septic shock.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Donnino, Mw" uniqKey="Donnino M">MW Donnino</name></author><author><name sortKey="Cocchi, Mn" uniqKey="Cocchi M">MN Cocchi</name></author><author><name sortKey="Salciccioli, Jd" uniqKey="Salciccioli J">JD Salciccioli</name></author><author><name sortKey="Kim, D" uniqKey="Kim D">D Kim</name></author><author><name sortKey="Naini, A" uniqKey="Naini A">A Naini</name></author><author><name sortKey="Buettner, C" uniqKey="Buettner C">C Buettner</name></author><author><name sortKey="Akuthota, P" uniqKey="Akuthota P">P Akuthota</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Singer, M" uniqKey="Singer M">M Singer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huet, O" uniqKey="Huet O">O Huet</name></author><author><name sortKey="Obata, R" uniqKey="Obata R">R Obata</name></author><author><name sortKey="Aubron, C" uniqKey="Aubron C">C Aubron</name></author><author><name sortKey="Spraul Davit, A" uniqKey="Spraul Davit A">A Spraul-Davit</name></author><author><name sortKey="Charpentier, J" uniqKey="Charpentier J">J Charpentier</name></author><author><name sortKey="Laplace, C" uniqKey="Laplace C">C Laplace</name></author><author><name sortKey="Nguyen Khoa, T" uniqKey="Nguyen Khoa T">T Nguyen-Khoa</name></author><author><name sortKey="Conti, M" uniqKey="Conti M">M Conti</name></author><author><name sortKey="Vicaut, E" uniqKey="Vicaut E">E Vicaut</name></author><author><name sortKey="Mira, Jp" uniqKey="Mira J">JP Mira</name></author><author><name sortKey="Duranteau, J" uniqKey="Duranteau J">J Duranteau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harrois, A" uniqKey="Harrois A">A Harrois</name></author><author><name sortKey="Huet, O" uniqKey="Huet O">O Huet</name></author><author><name sortKey="Duranteau, J" uniqKey="Duranteau J">J Duranteau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Quinzii, Cm" uniqKey="Quinzii C">CM Quinzii</name></author><author><name sortKey="Hirano, M" uniqKey="Hirano M">M Hirano</name></author><author><name sortKey="Dimauro, S" uniqKey="Dimauro S">S DiMauro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcmurray, Jj" uniqKey="Mcmurray J">JJ McMurray</name></author><author><name sortKey="Dunselman, P" uniqKey="Dunselman P">P Dunselman</name></author><author><name sortKey="Wedel, H" uniqKey="Wedel H">H Wedel</name></author><author><name sortKey="Cleland, Jg" uniqKey="Cleland J">JG Cleland</name></author><author><name sortKey="Lindberg, M" uniqKey="Lindberg M">M Lindberg</name></author><author><name sortKey="Hjalmarson, A" uniqKey="Hjalmarson A">A Hjalmarson</name></author><author><name sortKey="Kjekshus, J" uniqKey="Kjekshus J">J Kjekshus</name></author><author><name sortKey="Waagstein, F" uniqKey="Waagstein F">F Waagstein</name></author><author><name sortKey="Apetrei, E" uniqKey="Apetrei E">E Apetrei</name></author><author><name sortKey="Barrios, V" uniqKey="Barrios V">V Barrios</name></author><author><name sortKey="Bohm, M" uniqKey="Bohm M">M Böhm</name></author><author><name sortKey="Kamensk, G" uniqKey="Kamensk G">G Kamenský</name></author><author><name sortKey="Komajda, M" uniqKey="Komajda M">M Komajda</name></author><author><name sortKey="Mareev, V" uniqKey="Mareev V">V Mareev</name></author><author><name sortKey="Wikstrand, J" uniqKey="Wikstrand J">J Wikstrand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chuang, Yc" uniqKey="Chuang Y">YC Chuang</name></author><author><name sortKey="Chan, Jy" uniqKey="Chan J">JY Chan</name></author><author><name sortKey="Chang, Ay" uniqKey="Chang A">AY Chang</name></author><author><name sortKey="Sikorska, M" uniqKey="Sikorska M">M Sikorska</name></author><author><name sortKey="Borowy Borowski, H" uniqKey="Borowy Borowski H">H Borowy-Borowski</name></author><author><name sortKey="Liou, Cw" uniqKey="Liou C">CW Liou</name></author><author><name sortKey="Chan, Sh" uniqKey="Chan S">SH Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lowes, Da" uniqKey="Lowes D">DA Lowes</name></author><author><name sortKey="Thottakam, Bm" uniqKey="Thottakam B">BM Thottakam</name></author><author><name sortKey="Webster, Nr" uniqKey="Webster N">NR Webster</name></author><author><name sortKey="Murphy, Mp" uniqKey="Murphy M">MP Murphy</name></author><author><name sortKey="Galley, Hf" uniqKey="Galley H">HF Galley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Supinski, Gs" uniqKey="Supinski G">GS Supinski</name></author><author><name sortKey="Murphy, Mp" uniqKey="Murphy M">MP Murphy</name></author><author><name sortKey="Callahan, La" uniqKey="Callahan L">LA Callahan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brealey, Da" uniqKey="Brealey D">DA Brealey</name></author><author><name sortKey="Singer, M" uniqKey="Singer M">M Singer</name></author><author><name sortKey="Terblanche, M" uniqKey="Terblanche M">M Terblanche</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article" xml:lang="en"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Crit Care</journal-id><journal-id journal-id-type="iso-abbrev">Crit Care</journal-id><journal-title-group><journal-title>Critical Care</journal-title></journal-title-group><issn pub-type="ppub">1364-8535</issn><issn pub-type="epub">1466-609X</issn><publisher><publisher-name>BioMed Central</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22011617</article-id><article-id pub-id-type="pmc">3334745</article-id><article-id pub-id-type="publisher-id">cc10429</article-id><article-id pub-id-type="doi">10.1186/cc10429</article-id><article-categories><subj-group subj-group-type="heading"><subject>Commentary</subject></subj-group></article-categories><title-group><article-title>Coenzyme Q<sub>10 </sub>deficiency in septic shock patients</article-title></title-group><contrib-group><contrib contrib-type="author" id="A1"><name><surname>Dupic</surname><given-names>Laurent</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>laurent.dupic@nck.aphp.fr</email></contrib><contrib contrib-type="author" id="A2"><name><surname>Huet</surname><given-names>Olivier</given-names></name><xref ref-type="aff" rid="I2">2</xref><xref ref-type="aff" rid="I3">3</xref><email>Olivier.Huet@bakeridi.edu.au</email></contrib><contrib contrib-type="author" corresp="yes" id="A3"><name><surname>Duranteau</surname><given-names>Jacques</given-names></name><xref ref-type="aff" rid="I3">3</xref><email>jacques.duranteau@bct.aphp.fr</email></contrib></contrib-group><aff id="I1"><label>1</label>Assistance Publique - Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Réanimation pédiatrique, Université Paris Descartes, 149, rue de Sèvres, 75015 Paris, France</aff><aff id="I2"><label>2</label>Vascular Pharmacology Laboratory, BakerIDI Heart and Diabetes Institute, 75 Commercial Road, 3004 Melbourne, VIC, Australia</aff><aff id="I3"><label>3</label>Assistance Publique - Hôpitaux de Paris, Hôpital Bicêtre, Département d'Anesthésie-Réanimation, EA 3509 Université Paris Sud XI, France F-94275, Le Kremlin-Bicêtre, France</aff><pub-date pub-type="ppub"><year>2011</year></pub-date><pub-date pub-type="epub"><day>4</day><month>10</month><year>2011</year></pub-date><pmc-comment> PMC Release delay is 12 months and 0 days and was based on the epub date.</pmc-comment>
<pub-date pub-type="pmc-release"><day>4</day><month>10</month><year>2012</year></pub-date><volume>15</volume><issue>5</issue><fpage>194</fpage><lpage>194</lpage><permissions><copyright-statement>Copyright ©2011 BioMed Central Ltd</copyright-statement><copyright-year>2011</copyright-year><copyright-holder>BioMed Central Ltd</copyright-holder></permissions><self-uri xlink:href="http://ccforum.com/content/15/5/194"></self-uri><abstract><p>Donnino and colleagues provide new insights into the field of oxidative stress and mitochondrial dysfunction during septic shock. These authors suggest a coenzyme Q<sub>10 </sub>(CoQ<sub>10</sub>) deficiency in patients with septic shock. Larger prospective observational trials measuring CoQ<sub>10 </sub>in patients with septic shock are required to confirm the possibility of CoQ<sub>10 </sub>depletion. This study is a new step toward a study testing CoQ<sub>10 </sub>as a potential therapeutic agent for patients with septic shock.</p></abstract></article-meta></front></pmc><affiliations><list><country><li>Australie</li><li>France</li></country><region><li>Île-de-France</li></region><settlement><li>Paris</li></settlement><orgName><li>Université Paris-Descartes</li></orgName></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Dupic, Laurent" sort="Dupic, Laurent" uniqKey="Dupic L" first="Laurent" last="Dupic">Laurent Dupic</name></region><name sortKey="Duranteau, Jacques" sort="Duranteau, Jacques" uniqKey="Duranteau J" first="Jacques" last="Duranteau">Jacques Duranteau</name><name sortKey="Huet, Olivier" sort="Huet, Olivier" uniqKey="Huet O" first="Olivier" last="Huet">Olivier Huet</name></country><country name="Australie"><noRegion><name sortKey="Huet, Olivier" sort="Huet, Olivier" uniqKey="Huet O" first="Olivier" last="Huet">Olivier Huet</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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