European consensus conference on unruptured brain AVMs treatment (Supported by EANS, ESMINT, EGKS, and SINCH).
Identifieur interne : 004612 ( Ncbi/Curation ); précédent : 004611; suivant : 004613European consensus conference on unruptured brain AVMs treatment (Supported by EANS, ESMINT, EGKS, and SINCH).
Auteurs : Marco Cenzato [Italie] ; Edoardo Boccardi [Italie] ; Ettore Beghi [Italie] ; Peter Vajkoczy [Allemagne] ; Istvan Szikora [Hongrie] ; Enrico Motti [Italie] ; Luca Regli [Suisse] ; Andreas Raabe [Suisse] ; Shalva Eliava [Russie] ; Andreas Gruber [Autriche] ; Torstein R. Meling [Norvège] ; Mika Niemela [Finlande] ; Alberto Pasqualin [Italie] ; Andrey Golanov [Russie] ; Bengt Karlsson [Singapour] ; Andras Kemeny [Royaume-Uni] ; Roman Liscak [République tchèque] ; Bodo Lippitz [Royaume-Uni] ; Matthias Radatz [Royaume-Uni] ; Alessandro La Camera [Italie] ; René Chapot [Allemagne] ; Civan Islak [Turquie] ; Laurent Spelle [France] ; Alberto Debernardi [Italie] ; Elio Agostoni [Italie] ; Martina Revay [Italie] ; Michael K. Morgan [Australie]Source :
- Acta neurochirurgica [ 0942-0940 ] ; 2017.
Abstract
In December of 2016, a Consensus Conference on unruptured AVM treatment, involving 24 members of the three European societies dealing with the treatment of cerebral AVMs (EANS, ESMINT, and EGKS) was held in Milan, Italy. The panel made the following statements and general recommendations: (1) Brain arteriovenous malformation (AVM) is a complex disease associated with potentially severe natural history; (2) The results of a randomized trial (ARUBA) cannot be applied equally for all unruptured brain arteriovenous malformation (uBAVM) and for all treatment modalities; (3) Considering the multiple treatment modalities available, patients with uBAVMs should be evaluated by an interdisciplinary neurovascular team consisting of neurosurgeons, neurointerventionalists, radiosurgeons, and neurologists experienced in the diagnosis and treatment of brain AVM; (4) Balancing the risk of hemorrhage and the associated restrictions of everyday activities related to untreated unruptured AVMs against the risk of treatment, there are sufficient indications to treat unruptured AVMs grade 1 and 2 (Spetzler-Martin); (5) There may be indications for treating patients with higher grades, based on a case-to-case consensus decision of the experienced team; (6) If treatment is indicated, the primary strategy should be defined by the multidisciplinary team prior to the beginning of the treatment and should aim at complete eradication of the uBAVM; (7) After having considered the pros and cons of a randomized trial vs. a registry, the panel proposed a prospective European Multidisciplinary Registry.
DOI: 10.1007/s00701-017-3154-8
PubMed: 28389875
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Morgan</name><affiliation wicri:level="3"><nlm:affiliation>Neurosurgery, Macquaire University, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neurosurgery, Macquaire University, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28389875</idno><idno type="pmid">28389875</idno><idno type="doi">10.1007/s00701-017-3154-8</idno><idno type="wicri:Area/PubMed/Corpus">000B43</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000B43</idno><idno type="wicri:Area/PubMed/Curation">000B40</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000B40</idno><idno type="wicri:Area/PubMed/Checkpoint">000B40</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000B40</idno><idno type="wicri:Area/Ncbi/Merge">004612</idno><idno type="wicri:Area/Ncbi/Curation">004612</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">European consensus conference on unruptured brain AVMs treatment (Supported by EANS, ESMINT, EGKS, and SINCH).</title><author><name sortKey="Cenzato, Marco" sort="Cenzato, Marco" uniqKey="Cenzato M" first="Marco" last="Cenzato">Marco Cenzato</name><affiliation wicri:level="3"><nlm:affiliation>Neurosurgery, Grande Ospedale Metropolitano Niguarda, Milan, Italy. marco.cenzato@ospedaleniguarda.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Neurosurgery, Grande Ospedale Metropolitano Niguarda, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Boccardi, Edoardo" sort="Boccardi, Edoardo" uniqKey="Boccardi E" first="Edoardo" last="Boccardi">Edoardo Boccardi</name><affiliation wicri:level="3"><nlm:affiliation>Neuroradiology, Metropolitan Hospital Niguarda, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Neuroradiology, Metropolitan Hospital Niguarda, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Beghi, Ettore" sort="Beghi, Ettore" uniqKey="Beghi E" first="Ettore" last="Beghi">Ettore Beghi</name><affiliation wicri:level="3"><nlm:affiliation>Neurology, Methodologist, IRCCS Istituto Mario Negri, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Neurology, Methodologist, IRCCS Istituto Mario Negri, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Vajkoczy, Peter" sort="Vajkoczy, 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centrale</region></placeName></affiliation></author><author><name sortKey="Motti, Enrico" sort="Motti, Enrico" uniqKey="Motti E" first="Enrico" last="Motti">Enrico Motti</name><affiliation wicri:level="1"><nlm:affiliation>Radiosurgery, Ospedale Villa Maria di Cotignola, Ravenna, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Radiosurgery, Ospedale Villa Maria di Cotignola, Ravenna</wicri:regionArea><wicri:noRegion>Ravenna</wicri:noRegion></affiliation></author><author><name sortKey="Regli, Luca" sort="Regli, Luca" uniqKey="Regli L" first="Luca" last="Regli">Luca Regli</name><affiliation wicri:level="1"><nlm:affiliation>Neurosurgery, UniversitaetsSpital, Zurich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Neurosurgery, UniversitaetsSpital, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author><author><name sortKey="Raabe, Andreas" sort="Raabe, Andreas" uniqKey="Raabe A" first="Andreas" last="Raabe">Andreas Raabe</name><affiliation wicri:level="3"><nlm:affiliation>Neurosurgery, Inselspital, Bern, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Neurosurgery, Inselspital, Bern</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region type="région" nuts="3">Canton de Berne</region></placeName></affiliation></author><author><name sortKey="Eliava, Shalva" sort="Eliava, Shalva" uniqKey="Eliava S" first="Shalva" last="Eliava">Shalva Eliava</name><affiliation wicri:level="3"><nlm:affiliation>Neurosurgery, Burdenko Hospital, Moscow, Russia.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Neurosurgery, Burdenko Hospital, Moscow</wicri:regionArea><placeName><settlement type="city">Moscou</settlement><region>District fédéral central</region></placeName></affiliation></author><author><name sortKey="Gruber, Andreas" sort="Gruber, Andreas" uniqKey="Gruber A" first="Andreas" last="Gruber">Andreas Gruber</name><affiliation wicri:level="1"><nlm:affiliation>Neurosurgery and Neuroradiology, University Hospital, Lintz, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Neurosurgery and Neuroradiology, University Hospital, Lintz</wicri:regionArea><wicri:noRegion>Lintz</wicri:noRegion></affiliation></author><author><name sortKey="Meling, Torstein R" sort="Meling, Torstein R" uniqKey="Meling T" first="Torstein R" last="Meling">Torstein R. Meling</name><affiliation wicri:level="3"><nlm:affiliation>Neurosurgery, National Hospital, Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Neurosurgery, National Hospital, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Niemela, Mika" sort="Niemela, Mika" uniqKey="Niemela M" first="Mika" last="Niemela">Mika Niemela</name><affiliation wicri:level="1"><nlm:affiliation>Neurosurgery, University Hospital, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Neurosurgery, University Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Pasqualin, Alberto" sort="Pasqualin, Alberto" uniqKey="Pasqualin A" first="Alberto" last="Pasqualin">Alberto Pasqualin</name><affiliation wicri:level="1"><nlm:affiliation>Neurosurgery, Ospedale Maggiore Civile, Verona, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Neurosurgery, Ospedale Maggiore Civile, Verona</wicri:regionArea><wicri:noRegion>Verona</wicri:noRegion></affiliation></author><author><name sortKey="Golanov, Andrey" sort="Golanov, Andrey" uniqKey="Golanov A" first="Andrey" last="Golanov">Andrey Golanov</name><affiliation wicri:level="3"><nlm:affiliation>Radiosurgery, Burdenko Hospital, Moscow, Russia.</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Radiosurgery, Burdenko Hospital, Moscow</wicri:regionArea><placeName><settlement type="city">Moscou</settlement><region>District fédéral central</region></placeName></affiliation></author><author><name sortKey="Karlsson, Bengt" sort="Karlsson, Bengt" uniqKey="Karlsson B" first="Bengt" last="Karlsson">Bengt Karlsson</name><affiliation wicri:level="1"><nlm:affiliation>Radiosurgery, Singapore Gamma Knife Center, Singapore, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Radiosurgery, Singapore Gamma Knife Center, Singapore</wicri:regionArea><wicri:noRegion>Singapore</wicri:noRegion></affiliation></author><author><name sortKey="Kemeny, Andras" sort="Kemeny, Andras" uniqKey="Kemeny A" first="Andras" last="Kemeny">Andras Kemeny</name><affiliation wicri:level="1"><nlm:affiliation>Radiosurgery, Thornbury Radiosurgery Centre, Sheffield, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Radiosurgery, Thornbury Radiosurgery Centre, Sheffield</wicri:regionArea><wicri:noRegion>Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Liscak, Roman" sort="Liscak, Roman" uniqKey="Liscak R" first="Roman" last="Liscak">Roman Liscak</name><affiliation wicri:level="3"><nlm:affiliation>Radiosurgery, Na Homolce Hospital, Prague, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Radiosurgery, Na Homolce Hospital, Prague</wicri:regionArea><placeName><settlement type="city">Prague</settlement><region type="région" nuts="2">Bohême centrale</region></placeName></affiliation></author><author><name sortKey="Lippitz, Bodo" sort="Lippitz, Bodo" uniqKey="Lippitz B" first="Bodo" last="Lippitz">Bodo Lippitz</name><affiliation wicri:level="3"><nlm:affiliation>Radiosurgery, Bupa Cromwell Hospital, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Radiosurgery, Bupa Cromwell Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Radatz, Matthias" sort="Radatz, Matthias" uniqKey="Radatz M" first="Matthias" last="Radatz">Matthias Radatz</name><affiliation wicri:level="1"><nlm:affiliation>Radiosurgery, Royal Hallamshire Hospital, Sheffield, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Radiosurgery, Royal Hallamshire Hospital, Sheffield</wicri:regionArea><wicri:noRegion>Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="La Camera, Alessandro" sort="La Camera, Alessandro" uniqKey="La Camera A" first="Alessandro" last="La Camera">Alessandro La Camera</name><affiliation wicri:level="3"><nlm:affiliation>Radiosurgery, Grande Ospedale Metropolitano Niguarda, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Radiosurgery, Grande Ospedale Metropolitano Niguarda, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Chapot, Rene" sort="Chapot, Rene" uniqKey="Chapot R" first="René" last="Chapot">René Chapot</name><affiliation wicri:level="1"><nlm:affiliation>Neuroradiology, Krupp Hospital, Hessen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Neuroradiology, Krupp Hospital, Hessen</wicri:regionArea><wicri:noRegion>Hessen</wicri:noRegion><wicri:noRegion>Hessen</wicri:noRegion><wicri:noRegion>Hessen</wicri:noRegion></affiliation></author><author><name sortKey="Islak, Civan" sort="Islak, Civan" uniqKey="Islak C" first="Civan" last="Islak">Civan Islak</name><affiliation wicri:level="1"><nlm:affiliation>Neuroradiology, Cerrahpaşa Medical Faculty, İstanbul University, Istanbul, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Neuroradiology, Cerrahpaşa Medical Faculty, İstanbul University, Istanbul</wicri:regionArea><wicri:noRegion>Istanbul</wicri:noRegion></affiliation></author><author><name sortKey="Spelle, Laurent" sort="Spelle, Laurent" uniqKey="Spelle L" first="Laurent" last="Spelle">Laurent Spelle</name><affiliation wicri:level="3"><nlm:affiliation>Neuroradiology, Bicetre University Hospital, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Neuroradiology, Bicetre University Hospital, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Debernardi, Alberto" sort="Debernardi, Alberto" uniqKey="Debernardi A" first="Alberto" last="Debernardi">Alberto Debernardi</name><affiliation wicri:level="3"><nlm:affiliation>Neurosurgery, Grande Ospedale Metropolitano Niguarda, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Neurosurgery, Grande Ospedale Metropolitano Niguarda, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Agostoni, Elio" sort="Agostoni, Elio" uniqKey="Agostoni E" first="Elio" last="Agostoni">Elio Agostoni</name><affiliation wicri:level="3"><nlm:affiliation>Neurology, Grande Ospedale Metropolitano Niguarda, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Neurology, Grande Ospedale Metropolitano Niguarda, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Revay, Martina" sort="Revay, Martina" uniqKey="Revay M" first="Martina" last="Revay">Martina Revay</name><affiliation wicri:level="3"><nlm:affiliation>Neurosurgery, Grande Ospedale Metropolitano Niguarda, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Neurosurgery, Grande Ospedale Metropolitano Niguarda, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Morgan, Michael K" sort="Morgan, Michael K" uniqKey="Morgan M" first="Michael K" last="Morgan">Michael K. Morgan</name><affiliation wicri:level="3"><nlm:affiliation>Neurosurgery, Macquaire University, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Neurosurgery, Macquaire University, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author></analytic><series><title level="j">Acta neurochirurgica</title><idno type="eISSN">0942-0940</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In December of 2016, a Consensus Conference on unruptured AVM treatment, involving 24 members of the three European societies dealing with the treatment of cerebral AVMs (EANS, ESMINT, and EGKS) was held in Milan, Italy. The panel made the following statements and general recommendations: (1) Brain arteriovenous malformation (AVM) is a complex disease associated with potentially severe natural history; (2) The results of a randomized trial (ARUBA) cannot be applied equally for all unruptured brain arteriovenous malformation (uBAVM) and for all treatment modalities; (3) Considering the multiple treatment modalities available, patients with uBAVMs should be evaluated by an interdisciplinary neurovascular team consisting of neurosurgeons, neurointerventionalists, radiosurgeons, and neurologists experienced in the diagnosis and treatment of brain AVM; (4) Balancing the risk of hemorrhage and the associated restrictions of everyday activities related to untreated unruptured AVMs against the risk of treatment, there are sufficient indications to treat unruptured AVMs grade 1 and 2 (Spetzler-Martin); (5) There may be indications for treating patients with higher grades, based on a case-to-case consensus decision of the experienced team; (6) If treatment is indicated, the primary strategy should be defined by the multidisciplinary team prior to the beginning of the treatment and should aim at complete eradication of the uBAVM; (7) After having considered the pros and cons of a randomized trial vs. a registry, the panel proposed a prospective European Multidisciplinary Registry.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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