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European consensus conference on unruptured brain AVMs treatment (Supported by EANS, ESMINT, EGKS, and SINCH).

Identifieur interne : 000B43 ( PubMed/Corpus ); précédent : 000B42; suivant : 000B44

European consensus conference on unruptured brain AVMs treatment (Supported by EANS, ESMINT, EGKS, and SINCH).

Auteurs : Marco Cenzato ; Edoardo Boccardi ; Ettore Beghi ; Peter Vajkoczy ; Istvan Szikora ; Enrico Motti ; Luca Regli ; Andreas Raabe ; Shalva Eliava ; Andreas Gruber ; Torstein R. Meling ; Mika Niemela ; Alberto Pasqualin ; Andrey Golanov ; Bengt Karlsson ; Andras Kemeny ; Roman Liscak ; Bodo Lippitz ; Matthias Radatz ; Alessandro La Camera ; René Chapot ; Civan Islak ; Laurent Spelle ; Alberto Debernardi ; Elio Agostoni ; Martina Revay ; Michael K. Morgan

Source :

RBID : pubmed:28389875

Abstract

In December of 2016, a Consensus Conference on unruptured AVM treatment, involving 24 members of the three European societies dealing with the treatment of cerebral AVMs (EANS, ESMINT, and EGKS) was held in Milan, Italy. The panel made the following statements and general recommendations: (1) Brain arteriovenous malformation (AVM) is a complex disease associated with potentially severe natural history; (2) The results of a randomized trial (ARUBA) cannot be applied equally for all unruptured brain arteriovenous malformation (uBAVM) and for all treatment modalities; (3) Considering the multiple treatment modalities available, patients with uBAVMs should be evaluated by an interdisciplinary neurovascular team consisting of neurosurgeons, neurointerventionalists, radiosurgeons, and neurologists experienced in the diagnosis and treatment of brain AVM; (4) Balancing the risk of hemorrhage and the associated restrictions of everyday activities related to untreated unruptured AVMs against the risk of treatment, there are sufficient indications to treat unruptured AVMs grade 1 and 2 (Spetzler-Martin); (5) There may be indications for treating patients with higher grades, based on a case-to-case consensus decision of the experienced team; (6) If treatment is indicated, the primary strategy should be defined by the multidisciplinary team prior to the beginning of the treatment and should aim at complete eradication of the uBAVM; (7) After having considered the pros and cons of a randomized trial vs. a registry, the panel proposed a prospective European Multidisciplinary Registry.

DOI: 10.1007/s00701-017-3154-8
PubMed: 28389875

Links to Exploration step

pubmed:28389875

Le document en format XML

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<name sortKey="Karlsson, Bengt" sort="Karlsson, Bengt" uniqKey="Karlsson B" first="Bengt" last="Karlsson">Bengt Karlsson</name>
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<name sortKey="Kemeny, Andras" sort="Kemeny, Andras" uniqKey="Kemeny A" first="Andras" last="Kemeny">Andras Kemeny</name>
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<name sortKey="Lippitz, Bodo" sort="Lippitz, Bodo" uniqKey="Lippitz B" first="Bodo" last="Lippitz">Bodo Lippitz</name>
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<name sortKey="Radatz, Matthias" sort="Radatz, Matthias" uniqKey="Radatz M" first="Matthias" last="Radatz">Matthias Radatz</name>
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<name sortKey="La Camera, Alessandro" sort="La Camera, Alessandro" uniqKey="La Camera A" first="Alessandro" last="La Camera">Alessandro La Camera</name>
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<name sortKey="Chapot, Rene" sort="Chapot, Rene" uniqKey="Chapot R" first="René" last="Chapot">René Chapot</name>
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<nlm:affiliation>Neuroradiology, Krupp Hospital, Hessen, Germany.</nlm:affiliation>
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<name sortKey="Islak, Civan" sort="Islak, Civan" uniqKey="Islak C" first="Civan" last="Islak">Civan Islak</name>
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<nlm:affiliation>Neuroradiology, Cerrahpaşa Medical Faculty, İstanbul University, Istanbul, Turkey.</nlm:affiliation>
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<name sortKey="Spelle, Laurent" sort="Spelle, Laurent" uniqKey="Spelle L" first="Laurent" last="Spelle">Laurent Spelle</name>
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<name sortKey="Agostoni, Elio" sort="Agostoni, Elio" uniqKey="Agostoni E" first="Elio" last="Agostoni">Elio Agostoni</name>
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<title xml:lang="en">European consensus conference on unruptured brain AVMs treatment (Supported by EANS, ESMINT, EGKS, and SINCH).</title>
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<name sortKey="Boccardi, Edoardo" sort="Boccardi, Edoardo" uniqKey="Boccardi E" first="Edoardo" last="Boccardi">Edoardo Boccardi</name>
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<nlm:affiliation>Neuroradiology, Metropolitan Hospital Niguarda, Milan, Italy.</nlm:affiliation>
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<name sortKey="Beghi, Ettore" sort="Beghi, Ettore" uniqKey="Beghi E" first="Ettore" last="Beghi">Ettore Beghi</name>
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<nlm:affiliation>Neurology, Methodologist, IRCCS Istituto Mario Negri, Milan, Italy.</nlm:affiliation>
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<author>
<name sortKey="Vajkoczy, Peter" sort="Vajkoczy, Peter" uniqKey="Vajkoczy P" first="Peter" last="Vajkoczy">Peter Vajkoczy</name>
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<nlm:affiliation>Neurosurgery, Charitè Universitatetsmedizin, Berlin, Germany.</nlm:affiliation>
</affiliation>
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<name sortKey="Szikora, Istvan" sort="Szikora, Istvan" uniqKey="Szikora I" first="Istvan" last="Szikora">Istvan Szikora</name>
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<nlm:affiliation>Neuroradiology, National Institute of NeuroScience, Budapest, Hungary.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Motti, Enrico" sort="Motti, Enrico" uniqKey="Motti E" first="Enrico" last="Motti">Enrico Motti</name>
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<nlm:affiliation>Radiosurgery, Ospedale Villa Maria di Cotignola, Ravenna, Italy.</nlm:affiliation>
</affiliation>
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<name sortKey="Regli, Luca" sort="Regli, Luca" uniqKey="Regli L" first="Luca" last="Regli">Luca Regli</name>
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<nlm:affiliation>Neurosurgery, UniversitaetsSpital, Zurich, Switzerland.</nlm:affiliation>
</affiliation>
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<name sortKey="Raabe, Andreas" sort="Raabe, Andreas" uniqKey="Raabe A" first="Andreas" last="Raabe">Andreas Raabe</name>
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<nlm:affiliation>Neurosurgery, Inselspital, Bern, Switzerland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Eliava, Shalva" sort="Eliava, Shalva" uniqKey="Eliava S" first="Shalva" last="Eliava">Shalva Eliava</name>
<affiliation>
<nlm:affiliation>Neurosurgery, Burdenko Hospital, Moscow, Russia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Gruber, Andreas" sort="Gruber, Andreas" uniqKey="Gruber A" first="Andreas" last="Gruber">Andreas Gruber</name>
<affiliation>
<nlm:affiliation>Neurosurgery and Neuroradiology, University Hospital, Lintz, Austria.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Meling, Torstein R" sort="Meling, Torstein R" uniqKey="Meling T" first="Torstein R" last="Meling">Torstein R. Meling</name>
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<nlm:affiliation>Neurosurgery, National Hospital, Oslo, Norway.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Niemela, Mika" sort="Niemela, Mika" uniqKey="Niemela M" first="Mika" last="Niemela">Mika Niemela</name>
<affiliation>
<nlm:affiliation>Neurosurgery, University Hospital, Helsinki, Finland.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Pasqualin, Alberto" sort="Pasqualin, Alberto" uniqKey="Pasqualin A" first="Alberto" last="Pasqualin">Alberto Pasqualin</name>
<affiliation>
<nlm:affiliation>Neurosurgery, Ospedale Maggiore Civile, Verona, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Golanov, Andrey" sort="Golanov, Andrey" uniqKey="Golanov A" first="Andrey" last="Golanov">Andrey Golanov</name>
<affiliation>
<nlm:affiliation>Radiosurgery, Burdenko Hospital, Moscow, Russia.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Karlsson, Bengt" sort="Karlsson, Bengt" uniqKey="Karlsson B" first="Bengt" last="Karlsson">Bengt Karlsson</name>
<affiliation>
<nlm:affiliation>Radiosurgery, Singapore Gamma Knife Center, Singapore, Singapore.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Kemeny, Andras" sort="Kemeny, Andras" uniqKey="Kemeny A" first="Andras" last="Kemeny">Andras Kemeny</name>
<affiliation>
<nlm:affiliation>Radiosurgery, Thornbury Radiosurgery Centre, Sheffield, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Liscak, Roman" sort="Liscak, Roman" uniqKey="Liscak R" first="Roman" last="Liscak">Roman Liscak</name>
<affiliation>
<nlm:affiliation>Radiosurgery, Na Homolce Hospital, Prague, Czech Republic.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Lippitz, Bodo" sort="Lippitz, Bodo" uniqKey="Lippitz B" first="Bodo" last="Lippitz">Bodo Lippitz</name>
<affiliation>
<nlm:affiliation>Radiosurgery, Bupa Cromwell Hospital, London, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Radatz, Matthias" sort="Radatz, Matthias" uniqKey="Radatz M" first="Matthias" last="Radatz">Matthias Radatz</name>
<affiliation>
<nlm:affiliation>Radiosurgery, Royal Hallamshire Hospital, Sheffield, UK.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="La Camera, Alessandro" sort="La Camera, Alessandro" uniqKey="La Camera A" first="Alessandro" last="La Camera">Alessandro La Camera</name>
<affiliation>
<nlm:affiliation>Radiosurgery, Grande Ospedale Metropolitano Niguarda, Milan, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Chapot, Rene" sort="Chapot, Rene" uniqKey="Chapot R" first="René" last="Chapot">René Chapot</name>
<affiliation>
<nlm:affiliation>Neuroradiology, Krupp Hospital, Hessen, Germany.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Islak, Civan" sort="Islak, Civan" uniqKey="Islak C" first="Civan" last="Islak">Civan Islak</name>
<affiliation>
<nlm:affiliation>Neuroradiology, Cerrahpaşa Medical Faculty, İstanbul University, Istanbul, Turkey.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Spelle, Laurent" sort="Spelle, Laurent" uniqKey="Spelle L" first="Laurent" last="Spelle">Laurent Spelle</name>
<affiliation>
<nlm:affiliation>Neuroradiology, Bicetre University Hospital, Paris, France.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Debernardi, Alberto" sort="Debernardi, Alberto" uniqKey="Debernardi A" first="Alberto" last="Debernardi">Alberto Debernardi</name>
<affiliation>
<nlm:affiliation>Neurosurgery, Grande Ospedale Metropolitano Niguarda, Milan, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Agostoni, Elio" sort="Agostoni, Elio" uniqKey="Agostoni E" first="Elio" last="Agostoni">Elio Agostoni</name>
<affiliation>
<nlm:affiliation>Neurology, Grande Ospedale Metropolitano Niguarda, Milan, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Revay, Martina" sort="Revay, Martina" uniqKey="Revay M" first="Martina" last="Revay">Martina Revay</name>
<affiliation>
<nlm:affiliation>Neurosurgery, Grande Ospedale Metropolitano Niguarda, Milan, Italy.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Morgan, Michael K" sort="Morgan, Michael K" uniqKey="Morgan M" first="Michael K" last="Morgan">Michael K. Morgan</name>
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<nlm:affiliation>Neurosurgery, Macquaire University, Sydney, Australia.</nlm:affiliation>
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<div type="abstract" xml:lang="en">In December of 2016, a Consensus Conference on unruptured AVM treatment, involving 24 members of the three European societies dealing with the treatment of cerebral AVMs (EANS, ESMINT, and EGKS) was held in Milan, Italy. The panel made the following statements and general recommendations: (1) Brain arteriovenous malformation (AVM) is a complex disease associated with potentially severe natural history; (2) The results of a randomized trial (ARUBA) cannot be applied equally for all unruptured brain arteriovenous malformation (uBAVM) and for all treatment modalities; (3) Considering the multiple treatment modalities available, patients with uBAVMs should be evaluated by an interdisciplinary neurovascular team consisting of neurosurgeons, neurointerventionalists, radiosurgeons, and neurologists experienced in the diagnosis and treatment of brain AVM; (4) Balancing the risk of hemorrhage and the associated restrictions of everyday activities related to untreated unruptured AVMs against the risk of treatment, there are sufficient indications to treat unruptured AVMs grade 1 and 2 (Spetzler-Martin); (5) There may be indications for treating patients with higher grades, based on a case-to-case consensus decision of the experienced team; (6) If treatment is indicated, the primary strategy should be defined by the multidisciplinary team prior to the beginning of the treatment and should aim at complete eradication of the uBAVM; (7) After having considered the pros and cons of a randomized trial vs. a registry, the panel proposed a prospective European Multidisciplinary Registry.</div>
</front>
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<Day>08</Day>
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<Issue>6</Issue>
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<Year>2017</Year>
<Month>Jun</Month>
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<Title>Acta neurochirurgica</Title>
<ISOAbbreviation>Acta Neurochir (Wien)</ISOAbbreviation>
</Journal>
<ArticleTitle>European consensus conference on unruptured brain AVMs treatment (Supported by EANS, ESMINT, EGKS, and SINCH).</ArticleTitle>
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<Abstract>
<AbstractText>In December of 2016, a Consensus Conference on unruptured AVM treatment, involving 24 members of the three European societies dealing with the treatment of cerebral AVMs (EANS, ESMINT, and EGKS) was held in Milan, Italy. The panel made the following statements and general recommendations: (1) Brain arteriovenous malformation (AVM) is a complex disease associated with potentially severe natural history; (2) The results of a randomized trial (ARUBA) cannot be applied equally for all unruptured brain arteriovenous malformation (uBAVM) and for all treatment modalities; (3) Considering the multiple treatment modalities available, patients with uBAVMs should be evaluated by an interdisciplinary neurovascular team consisting of neurosurgeons, neurointerventionalists, radiosurgeons, and neurologists experienced in the diagnosis and treatment of brain AVM; (4) Balancing the risk of hemorrhage and the associated restrictions of everyday activities related to untreated unruptured AVMs against the risk of treatment, there are sufficient indications to treat unruptured AVMs grade 1 and 2 (Spetzler-Martin); (5) There may be indications for treating patients with higher grades, based on a case-to-case consensus decision of the experienced team; (6) If treatment is indicated, the primary strategy should be defined by the multidisciplinary team prior to the beginning of the treatment and should aim at complete eradication of the uBAVM; (7) After having considered the pros and cons of a randomized trial vs. a registry, the panel proposed a prospective European Multidisciplinary Registry.</AbstractText>
</Abstract>
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<LastName>Cenzato</LastName>
<ForeName>Marco</ForeName>
<Initials>M</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0003-0283-7421</Identifier>
<AffiliationInfo>
<Affiliation>Neurosurgery, Grande Ospedale Metropolitano Niguarda, Milan, Italy. marco.cenzato@ospedaleniguarda.it.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Boccardi</LastName>
<ForeName>Edoardo</ForeName>
<Initials>E</Initials>
<AffiliationInfo>
<Affiliation>Neuroradiology, Metropolitan Hospital Niguarda, Milan, Italy.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y">
<LastName>Beghi</LastName>
<ForeName>Ettore</ForeName>
<Initials>E</Initials>
<AffiliationInfo>
<Affiliation>Neurology, Methodologist, IRCCS Istituto Mario Negri, Milan, Italy.</Affiliation>
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