Dynamics of end expiratory lung volume after changing positive end-expiratory pressure in acute respiratory distress syndrome patients
Identifieur interne : 002A78 ( Ncbi/Checkpoint ); précédent : 002A77; suivant : 002A79Dynamics of end expiratory lung volume after changing positive end-expiratory pressure in acute respiratory distress syndrome patients
Auteurs : Aude Garnero [France] ; David Tuxen ; Gaëlle Corno [France] ; Jacques Durand-Gasselin [France] ; Carol Hodgson ; Jean-Michel Arnal [France, Suisse]Source :
- Critical Care [ 1364-8535 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- methods : Positive-Pressure Respiration.
- physiopathology : Lung, Respiratory Distress Syndrome, Adult.
- therapy : Respiratory Distress Syndrome, Adult.
- Aged, Female, Humans, Lung Volume Measurements, Male, Prospective Studies, Time Factors.
Abstract
Lung recruitment maneuvers followed by an individually titrated positive end-expiratory pressure (PEEP) are the key components of the open lung ventilation strategy in acute respiratory distress syndrome (ARDS). The staircase recruitment maneuver is a step-by-step increase in PEEP followed by a decremental PEEP trial. The duration of each step is usually 2 minutes without physiologic rationale.
In this prospective study, we measured the dynamic end-expiratory lung volume changes (ΔEELV) during an increase and decrease in PEEP to determine the optimal duration for each step. PEEP was progressively increased from 5 to 40 cmH2O and then decreased from 40 to 5 cmH2O in steps of 5 cmH2O every 2.5 minutes. The dynamic of ΔEELV was measured by direct spirometry as the difference between inspiratory and expiratory tidal volumes over 2.5 minutes following each increase and decrease in PEEP. ΔEELV was separated between the expected increased volume, calculated as the product of the respiratory system compliance by the change in PEEP, and the additional volume.
Twenty-six early onset moderate or severe ARDS patients were included. Data are expressed as median [25th-75th quartiles]. During the increase in PEEP, the expected increased volume was achieved within 2[2-2] breaths. During the decrease in PEEP, the expected decreased volume was achieved within 1 [1–1] breath, and 95 % of the additional decreased volume was achieved within 8 [2–15] breaths. Completion of volume changes in 99 % of both increase and decrease in PEEP events required 29 breaths.
In early ARDS, most of the ΔEELV occurs within the first minute, and change is completed within 2 minutes, following an increase or decrease in PEEP.
Url:
DOI: 10.1186/s13054-015-1044-0
PubMed: 26383835
PubMed Central: 4574463
Affiliations:
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<series><title level="j">Critical Care</title>
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<term>Male</term>
<term>Positive-Pressure Respiration (methods)</term>
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<term>Respiratory Distress Syndrome, Adult (physiopathology)</term>
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<term>Poumon (physiopathologie)</term>
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<term>Syndrome de détresse respiratoire de l'adulte ()</term>
<term>Syndrome de détresse respiratoire de l'adulte (physiopathologie)</term>
<term>Ventilation à pression positive ()</term>
<term>Études prospectives</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Positive-Pressure Respiration</term>
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<term>Syndrome de détresse respiratoire de l'adulte</term>
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<term>Respiratory Distress Syndrome, Adult</term>
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<term>Humans</term>
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<term>Prospective Studies</term>
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<term>Mesure des volumes pulmonaires</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Syndrome de détresse respiratoire de l'adulte</term>
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<front><div type="abstract" xml:lang="en"><sec><title>Introduction</title>
<p>Lung recruitment maneuvers followed by an individually titrated positive end-expiratory pressure (PEEP) are the key components of the open lung ventilation strategy in acute respiratory distress syndrome (ARDS). The staircase recruitment maneuver is a step-by-step increase in PEEP followed by a decremental PEEP trial. The duration of each step is usually 2 minutes without physiologic rationale.</p>
</sec>
<sec><title>Methods</title>
<p>In this prospective study, we measured the dynamic end-expiratory lung volume changes (ΔEELV) during an increase and decrease in PEEP to determine the optimal duration for each step. PEEP was progressively increased from 5 to 40 cmH<sub>2</sub>
O and then decreased from 40 to 5 cmH<sub>2</sub>
O in steps of 5 cmH<sub>2</sub>
O every 2.5 minutes. The dynamic of ΔEELV was measured by direct spirometry as the difference between inspiratory and expiratory tidal volumes over 2.5 minutes following each increase and decrease in PEEP. ΔEELV was separated between the expected increased volume, calculated as the product of the respiratory system compliance by the change in PEEP, and the additional volume.</p>
</sec>
<sec><title>Results</title>
<p>Twenty-six early onset moderate or severe ARDS patients were included. Data are expressed as median [25th-75th quartiles]. During the increase in PEEP, the expected increased volume was achieved within 2[2-2] breaths. During the decrease in PEEP, the expected decreased volume was achieved within 1 [1–1] breath, and 95 % of the additional decreased volume was achieved within 8 [2–15] breaths. Completion of volume changes in 99 % of both increase and decrease in PEEP events required 29 breaths.</p>
</sec>
<sec><title>Conclusions</title>
<p>In early ARDS, most of the ΔEELV occurs within the first minute, and change is completed within 2 minutes, following an increase or decrease in PEEP.</p>
</sec>
</div>
</front>
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</author>
<author><name sortKey="Cressoni, M" uniqKey="Cressoni M">M Cressoni</name>
</author>
<author><name sortKey="Chiumello, D" uniqKey="Chiumello D">D Chiumello</name>
</author>
<author><name sortKey="Ranieri, M" uniqKey="Ranieri M">M Ranieri</name>
</author>
<author><name sortKey="Quintel, M" uniqKey="Quintel M">M Quintel</name>
</author>
<author><name sortKey="Russo, Sg" uniqKey="Russo S">SG Russo</name>
</author>
</analytic>
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</author>
<author><name sortKey="Mascheroni, D" uniqKey="Mascheroni D">D Mascheroni</name>
</author>
<author><name sortKey="Caironi, P" uniqKey="Caironi P">P Caironi</name>
</author>
<author><name sortKey="Pelosi, P" uniqKey="Pelosi P">P Pelosi</name>
</author>
<author><name sortKey="Ronzoni, G" uniqKey="Ronzoni G">G Ronzoni</name>
</author>
<author><name sortKey="Mondino, M" uniqKey="Mondino M">M Mondino</name>
</author>
</analytic>
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<biblStruct><analytic><author><name sortKey="Suzumura, Ea" uniqKey="Suzumura E">EA Suzumura</name>
</author>
<author><name sortKey="Figueir, M" uniqKey="Figueir M">M Figueiró</name>
</author>
<author><name sortKey="Normilio Silva, K" uniqKey="Normilio Silva K">K Normilio-Silva</name>
</author>
<author><name sortKey="Laranjeira, L" uniqKey="Laranjeira L">L Laranjeira</name>
</author>
<author><name sortKey="Oliveira, C" uniqKey="Oliveira C">C Oliveira</name>
</author>
<author><name sortKey="Buehler, Am" uniqKey="Buehler A">AM Buehler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lapinsky, Se" uniqKey="Lapinsky S">SE Lapinsky</name>
</author>
<author><name sortKey="Aubin, M" uniqKey="Aubin M">M Aubin</name>
</author>
<author><name sortKey="Mehta, S" uniqKey="Mehta S">S Mehta</name>
</author>
<author><name sortKey="Boiteau, P" uniqKey="Boiteau P">P Boiteau</name>
</author>
<author><name sortKey="Slutsky, As" uniqKey="Slutsky A">AS Slutsky</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="De Matos, Gfj" uniqKey="De Matos G">GFJ de Matos</name>
</author>
<author><name sortKey="Stanzani, F" uniqKey="Stanzani F">F Stanzani</name>
</author>
<author><name sortKey="Passos, Rh" uniqKey="Passos R">RH Passos</name>
</author>
<author><name sortKey="Fontana, Mf" uniqKey="Fontana M">MF Fontana</name>
</author>
<author><name sortKey="Albaladejo, R" uniqKey="Albaladejo R">R Albaladejo</name>
</author>
<author><name sortKey="Caserta, Re" uniqKey="Caserta R">RE Caserta</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Borges, Jb" uniqKey="Borges J">JB Borges</name>
</author>
<author><name sortKey="Okamoto, Vn" uniqKey="Okamoto V">VN Okamoto</name>
</author>
<author><name sortKey="Matos, Gfj" uniqKey="Matos G">GFJ Matos</name>
</author>
<author><name sortKey="Caramez, Mp" uniqKey="Caramez M">MP Caramez</name>
</author>
<author><name sortKey="Arantes, Pr" uniqKey="Arantes P">PR Arantes</name>
</author>
<author><name sortKey="Barros, F" uniqKey="Barros F">F Barros</name>
</author>
</analytic>
</biblStruct>
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</author>
<author><name sortKey="Tuxen, Dv" uniqKey="Tuxen D">DV Tuxen</name>
</author>
<author><name sortKey="Davies, Ar" uniqKey="Davies A">AR Davies</name>
</author>
<author><name sortKey="Bailey, Mj" uniqKey="Bailey M">MJ Bailey</name>
</author>
<author><name sortKey="Higgins, Am" uniqKey="Higgins A">AM Higgins</name>
</author>
<author><name sortKey="Holland, Ae" uniqKey="Holland A">AE Holland</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hodgson, Cl" uniqKey="Hodgson C">CL Hodgson</name>
</author>
<author><name sortKey="Tuxen, Dv" uniqKey="Tuxen D">DV Tuxen</name>
</author>
<author><name sortKey="Bailey, Mj" uniqKey="Bailey M">MJ Bailey</name>
</author>
<author><name sortKey="Holland, Ae" uniqKey="Holland A">AE Holland</name>
</author>
<author><name sortKey="Keating, Jl" uniqKey="Keating J">JL Keating</name>
</author>
<author><name sortKey="Pilcher, D" uniqKey="Pilcher D">D Pilcher</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Maggiore, Sm" uniqKey="Maggiore S">SM Maggiore</name>
</author>
<author><name sortKey="Jonson, B" uniqKey="Jonson B">B Jonson</name>
</author>
<author><name sortKey="Richard, Jc" uniqKey="Richard J">JC Richard</name>
</author>
<author><name sortKey="Jaber, S" uniqKey="Jaber S">S Jaber</name>
</author>
<author><name sortKey="Lemaire, F" uniqKey="Lemaire F">F Lemaire</name>
</author>
<author><name sortKey="Brochard, L" uniqKey="Brochard L">L Brochard</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chiumello, D" uniqKey="Chiumello D">D Chiumello</name>
</author>
<author><name sortKey="Coppola, S" uniqKey="Coppola S">S Coppola</name>
</author>
<author><name sortKey="Froio, S" uniqKey="Froio S">S Froio</name>
</author>
<author><name sortKey="Mietto, C" uniqKey="Mietto C">C Mietto</name>
</author>
<author><name sortKey="Brazzi, L" uniqKey="Brazzi L">L Brazzi</name>
</author>
<author><name sortKey="Carlesso, E" uniqKey="Carlesso E">E Carlesso</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
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<author><name sortKey="Forel, Jm" uniqKey="Forel J">JM Forel</name>
</author>
<author><name sortKey="Gacouin, A" uniqKey="Gacouin A">A Gacouin</name>
</author>
<author><name sortKey="Penot Ragon, C" uniqKey="Penot Ragon C">C Penot-Ragon</name>
</author>
<author><name sortKey="Perrin, G" uniqKey="Perrin G">G Perrin</name>
</author>
<author><name sortKey="Loundou, A" uniqKey="Loundou A">A Loundou</name>
</author>
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</author>
<author><name sortKey="Ozanne, Gm" uniqKey="Ozanne G">GM Ozanne</name>
</author>
<author><name sortKey="Zinn, Se" uniqKey="Zinn S">SE Zinn</name>
</author>
<author><name sortKey="Fairley, Hb" uniqKey="Fairley H">HB Fairley</name>
</author>
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</author>
<author><name sortKey="Moller, K" uniqKey="Moller K">K Möller</name>
</author>
<author><name sortKey="Schumann, S" uniqKey="Schumann S">S Schumann</name>
</author>
<author><name sortKey="Kuhlen, R" uniqKey="Kuhlen R">R Kuhlen</name>
</author>
<author><name sortKey="Sydow, M" uniqKey="Sydow M">M Sydow</name>
</author>
<author><name sortKey="Putensen, C" uniqKey="Putensen C">C Putensen</name>
</author>
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</author>
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</author>
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</author>
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</author>
<author><name sortKey="Wysocki, M" uniqKey="Wysocki M">M Wysocki</name>
</author>
<author><name sortKey="Demory, D" uniqKey="Demory D">D Demory</name>
</author>
<author><name sortKey="Donati, S" uniqKey="Donati S">S Donati</name>
</author>
<author><name sortKey="Granier, I" uniqKey="Granier I">I Granier</name>
</author>
</analytic>
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</author>
<author><name sortKey="Zinserling, J" uniqKey="Zinserling J">J Zinserling</name>
</author>
<author><name sortKey="Muders, T" uniqKey="Muders T">T Muders</name>
</author>
<author><name sortKey="Varelmann, D" uniqKey="Varelmann D">D Varelmann</name>
</author>
<author><name sortKey="Gunther, U" uniqKey="Gunther U">U Günther</name>
</author>
<author><name sortKey="Von Der Groeben, C" uniqKey="Von Der Groeben C">C von der Groeben</name>
</author>
</analytic>
</biblStruct>
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</author>
<author><name sortKey="Lundin, S" uniqKey="Lundin S">S Lundin</name>
</author>
<author><name sortKey="Stenqvist, O" uniqKey="Stenqvist O">O Stenqvist</name>
</author>
<author><name sortKey="Lindgren, S" uniqKey="Lindgren S">S Lindgren</name>
</author>
</analytic>
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</author>
</analytic>
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</author>
<author><name sortKey="Odenstedt, H" uniqKey="Odenstedt H">H Odenstedt</name>
</author>
<author><name sortKey="Oleg Rd, C" uniqKey="Oleg Rd C">C Olegård</name>
</author>
<author><name sortKey="Sondergaard, S" uniqKey="Sondergaard S">S Söndergaard</name>
</author>
<author><name sortKey="Lundin, S" uniqKey="Lundin S">S Lundin</name>
</author>
<author><name sortKey="Stenqvist, O" uniqKey="Stenqvist O">O Stenqvist</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gattinoni, L" uniqKey="Gattinoni L">L Gattinoni</name>
</author>
<author><name sortKey="Pelosi, P" uniqKey="Pelosi P">P Pelosi</name>
</author>
<author><name sortKey="Suter, Pm" uniqKey="Suter P">PM Suter</name>
</author>
<author><name sortKey="Pedoto, A" uniqKey="Pedoto A">A Pedoto</name>
</author>
<author><name sortKey="Vercesi, P" uniqKey="Vercesi P">P Vercesi</name>
</author>
<author><name sortKey="Lissoni, A" uniqKey="Lissoni A">A Lissoni</name>
</author>
</analytic>
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