Psychosocial variables are associated with being wait-listed, but not with receiving a kidney transplant in the Dialysis Outcomes and Practice Patterns Study (DOPPS)
Identifieur interne : 005C64 ( Main/Merge ); précédent : 005C63; suivant : 005C65Psychosocial variables are associated with being wait-listed, but not with receiving a kidney transplant in the Dialysis Outcomes and Practice Patterns Study (DOPPS)
Auteurs : Lilla Szeifert [Hongrie] ; Jennifer L. Bragg-Gresham [États-Unis] ; Jyothi Thumma [États-Unis] ; Brenda W. Gillespie [États-Unis] ; Istvan Mucsi [Hongrie, Canada] ; Bruce M. Robinson [États-Unis] ; Ronald L. Pisoni [États-Unis] ; Alex Disney [Australie] ; Christian Combe [France] ; Friedrich K. Port [États-Unis]Source :
- Nephrology, dialysis, transplantation : (Print) [ 0931-0509 ] ; 2012.
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Abstract
Background. Psychosocial factors are associated with clinical outcomes in patients with end-stage renal disease. It is not known if self-reported depression and quality of life influence the likelihood of being wait-listed and receiving a transplant. Methods. Prevalent cross section of 18- to 65-year-old hemodialysis (HD) patients in the USA (N = 2033) and seven European countries (N = 4350) from the Dialysis Outcomes and Practice Patterns Study phase II and III was analyzed. Wait-listed patients (N = 1838) were followed until kidney transplantation. Self-reported depressive symptoms were assessed by the Center for Epidemiologic Studies-Depression scale, 10-item version (CES-D) and health-related quality of life (HR-QoL) by the Kidney Disease Quality of Life Short Form 12 scale Physical Component Score (PCS). Results. At study entry, 27% (USA) to 53% (UK) of patients were wait-listed in participating countries. Variables associated with lower odds of being on the waiting list included worse HR-QoL, more severe depressive symptoms, older age, fewer years of education, lower serum albumin, lower hemoglobin, shorter time on dialysis and presence of multiple comorbid conditions. Among wait-listed patients, significantly lower transplantation rates were seen for females, blacks, patients having prior transplantation and multiple comorbid conditions but not PCS or CES-D. Conclusions. Fewer depressive symptoms and better HR-QoL are associated with being on the waiting list in prevalent HD patients but not with receiving a kidney transplant among wait-listed dialysis patients. Regular assessment of subjective well-being may help identify patients with reduced access to wait-listing and kidney transplantation.
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Bragg-Gresham</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Arbor Research Collaborative for Health</s1><s2>Ann Arbor, MI</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Arbor Research Collaborative for Health</wicri:noRegion></affiliation></author><author><name sortKey="Thumma, Jyothi" sort="Thumma, Jyothi" uniqKey="Thumma J" first="Jyothi" last="Thumma">Jyothi Thumma</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Arbor Research Collaborative for Health</s1><s2>Ann Arbor, MI</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Arbor Research Collaborative for Health</wicri:noRegion></affiliation></author><author><name sortKey="Gillespie, Brenda W" sort="Gillespie, Brenda W" uniqKey="Gillespie B" first="Brenda W." last="Gillespie">Brenda W. Gillespie</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>University of Michigan</s1><s2>Ann Arbor, MI</s2><s3>USA</s3><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>University of Michigan</wicri:noRegion></affiliation></author><author><name sortKey="Mucsi, Istvan" sort="Mucsi, Istvan" uniqKey="Mucsi I" first="Istvan" last="Mucsi">Istvan Mucsi</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Institute of Behavioral Sciences, Semmelweis University</s1><s2>Budapest</s2><s3>HUN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Hongrie</country><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Medicine, Division of Nephrology, McGill University Health Centre, Royal Victoria Hospital</s1><s2>Montreal</s2><s3>CAN</s3><sZ>5 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Robinson, Bruce M" sort="Robinson, Bruce M" uniqKey="Robinson B" first="Bruce M." last="Robinson">Bruce M. Robinson</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Arbor Research Collaborative for Health</s1><s2>Ann Arbor, MI</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Arbor Research Collaborative for Health</wicri:noRegion></affiliation></author><author><name sortKey="Pisoni, Ronald L" sort="Pisoni, Ronald L" uniqKey="Pisoni R" first="Ronald L." last="Pisoni">Ronald L. Pisoni</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Arbor Research Collaborative for Health</s1><s2>Ann Arbor, MI</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Arbor Research Collaborative for Health</wicri:noRegion></affiliation></author><author><name sortKey="Disney, Alex" sort="Disney, Alex" uniqKey="Disney A" first="Alex" last="Disney">Alex Disney</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Queen Elizabeth Hospital</s1><s2>Woodville</s2><s3>AUS</s3><sZ>8 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Queen Elizabeth Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Combe, Christian" sort="Combe, Christian" uniqKey="Combe C" first="Christian" last="Combe">Christian Combe</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Hôpital Pellegrin</s1><s2>Bordeaux</s2><s3>FRA</s3><sZ>9 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Port, Friedrich K" sort="Port, Friedrich K" uniqKey="Port F" first="Friedrich K." last="Port">Friedrich K. Port</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Arbor Research Collaborative for Health</s1><s2>Ann Arbor, MI</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>6 aut.</sZ><sZ>7 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Arbor Research Collaborative for Health</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Nephrology, dialysis, transplantation : (Print)</title><title level="j" type="abbreviated">Nephrol. dial. transplant. : (Print)</title><idno type="ISSN">0931-0509</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Nephrology, dialysis, transplantation : (Print)</title><title level="j" type="abbreviated">Nephrol. dial. transplant. : (Print)</title><idno type="ISSN">0931-0509</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Dialysis</term><term>Extrarenal dialysis</term><term>Hemodialysis</term><term>Prognosis</term><term>Psychosocial factor</term><term>Quality of life</term><term>Renal failure</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Insuffisance rénale</term><term>Dialyse</term><term>Hémodialyse</term><term>Pronostic</term><term>Qualité de vie</term><term>Facteur psychosocial</term><term>Epuration extrarénale</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background. Psychosocial factors are associated with clinical outcomes in patients with end-stage renal disease. It is not known if self-reported depression and quality of life influence the likelihood of being wait-listed and receiving a transplant. Methods. Prevalent cross section of 18- to 65-year-old hemodialysis (HD) patients in the USA (N = 2033) and seven European countries (N = 4350) from the Dialysis Outcomes and Practice Patterns Study phase II and III was analyzed. Wait-listed patients (N = 1838) were followed until kidney transplantation. Self-reported depressive symptoms were assessed by the Center for Epidemiologic Studies-Depression scale, 10-item version (CES-D) and health-related quality of life (HR-QoL) by the Kidney Disease Quality of Life Short Form 12 scale Physical Component Score (PCS). Results. At study entry, 27% (USA) to 53% (UK) of patients were wait-listed in participating countries. Variables associated with lower odds of being on the waiting list included worse HR-QoL, more severe depressive symptoms, older age, fewer years of education, lower serum albumin, lower hemoglobin, shorter time on dialysis and presence of multiple comorbid conditions. Among wait-listed patients, significantly lower transplantation rates were seen for females, blacks, patients having prior transplantation and multiple comorbid conditions but not PCS or CES-D. Conclusions. Fewer depressive symptoms and better HR-QoL are associated with being on the waiting list in prevalent HD patients but not with receiving a kidney transplant among wait-listed dialysis patients. Regular assessment of subjective well-being may help identify patients with reduced access to wait-listing and kidney transplantation.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Canada</li><li>France</li><li>Hongrie</li><li>États-Unis</li></country><region><li>Aquitaine</li><li>Hongrie centrale</li><li>Nouvelle-Aquitaine</li><li>Québec</li></region><settlement><li>Bordeaux</li><li>Budapest</li><li>Montréal</li></settlement></list><tree><country name="Hongrie"><region name="Hongrie centrale"><name sortKey="Szeifert, Lilla" sort="Szeifert, Lilla" uniqKey="Szeifert L" first="Lilla" last="Szeifert">Lilla Szeifert</name></region><name sortKey="Mucsi, Istvan" sort="Mucsi, Istvan" uniqKey="Mucsi I" first="Istvan" last="Mucsi">Istvan Mucsi</name></country><country name="États-Unis"><noRegion><name sortKey="Bragg Gresham, Jennifer L" sort="Bragg Gresham, Jennifer L" uniqKey="Bragg Gresham J" first="Jennifer L." last="Bragg-Gresham">Jennifer L. Bragg-Gresham</name></noRegion><name sortKey="Gillespie, Brenda W" sort="Gillespie, Brenda W" uniqKey="Gillespie B" first="Brenda W." last="Gillespie">Brenda W. Gillespie</name><name sortKey="Pisoni, Ronald L" sort="Pisoni, Ronald L" uniqKey="Pisoni R" first="Ronald L." last="Pisoni">Ronald L. Pisoni</name><name sortKey="Port, Friedrich K" sort="Port, Friedrich K" uniqKey="Port F" first="Friedrich K." last="Port">Friedrich K. Port</name><name sortKey="Robinson, Bruce M" sort="Robinson, Bruce M" uniqKey="Robinson B" first="Bruce M." last="Robinson">Bruce M. Robinson</name><name sortKey="Thumma, Jyothi" sort="Thumma, Jyothi" uniqKey="Thumma J" first="Jyothi" last="Thumma">Jyothi Thumma</name></country><country name="Canada"><region name="Québec"><name sortKey="Mucsi, Istvan" sort="Mucsi, Istvan" uniqKey="Mucsi I" first="Istvan" last="Mucsi">Istvan Mucsi</name></region></country><country name="Australie"><noRegion><name sortKey="Disney, Alex" sort="Disney, Alex" uniqKey="Disney A" first="Alex" last="Disney">Alex Disney</name></noRegion></country><country name="France"><region name="Nouvelle-Aquitaine"><name sortKey="Combe, Christian" sort="Combe, Christian" uniqKey="Combe C" first="Christian" last="Combe">Christian Combe</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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