Global Aesthetics Consensus: Botulinum Toxin Type A—Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications
Identifieur interne : 001E14 ( Main/Merge ); précédent : 001E13; suivant : 001E15Global Aesthetics Consensus: Botulinum Toxin Type A—Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications
Auteurs : Hema Sundaram ; Massimo Signorini ; Steven Liew ; Ada R. Trindade De Almeida ; Yan Wu ; André Vieira Braz ; Steven Fagien ; Greg J. Goodman ; Gary Monheit ; Hervé RaspaldoSource :
- Plastic and Reconstructive Surgery [ 0032-1052 ] ; 2016.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Consensus, Facteurs de l'âge, Femelle, Guides de bonnes pratiques cliniques comme sujet, Humains, Injections sous-cutanées, Mâle, Médecine factuelle, Neurotoxines (administration et posologie), Neurotoxines (effets indésirables), Rajeunissement (physiologie), Résultat thérapeutique, Satisfaction du patient (), Sujet âgé, Techniques cosmétiques (normes), Toxines botuliniques de type A (effets indésirables), Toxines botuliniques de type A (usage thérapeutique), Vieillissement de la peau (), Évaluation des risques.
- MESH :
- administration et posologie : Neurotoxines.
- effets indésirables : Neurotoxines, Toxines botuliniques de type A.
- normes : Techniques cosmétiques.
- physiologie : Rajeunissement.
- usage thérapeutique : Toxines botuliniques de type A.
- Adulte d'âge moyen, Consensus, Facteurs de l'âge, Femelle, Guides de bonnes pratiques cliniques comme sujet, Humains, Injections sous-cutanées, Mâle, Médecine factuelle, Résultat thérapeutique, Satisfaction du patient, Sujet âgé, Vieillissement de la peau, Évaluation des risques.
English descriptors
- KwdEn :
- Age Factors, Aged, Botulinum Toxins, Type A (adverse effects), Botulinum Toxins, Type A (therapeutic use), Consensus, Cosmetic Techniques (standards), Evidence-Based Medicine, Female, Humans, Injections, Subcutaneous, Male, Middle Aged, Neurotoxins (administration & dosage), Neurotoxins (adverse effects), Patient Satisfaction (statistics & numerical data), Practice Guidelines as Topic, Rejuvenation (physiology), Risk Assessment, Skin Aging (drug effects), Treatment Outcome.
- MESH :
- chemical , administration & dosage : Neurotoxins.
- chemical , adverse effects : Botulinum Toxins, Type A, Neurotoxins.
- chemical , therapeutic use : Botulinum Toxins, Type A.
- drug effects : Skin Aging.
- physiology : Rejuvenation.
- standards : Cosmetic Techniques.
- statistics & numerical data : Patient Satisfaction.
- Age Factors, Aged, Consensus, Evidence-Based Medicine, Female, Humans, Injections, Subcutaneous, Male, Middle Aged, Practice Guidelines as Topic, Risk Assessment, Treatment Outcome.
Abstract
Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide, with a high rate of efficacy and patient satisfaction.
A multinational, multidisciplinary group of plastic surgeons and dermatologists convened the Global Aesthetics Consensus Group to develop updated consensus recommendations with a worldwide perspective for botulinum toxin and hyaluronic acid fillers. This publication on botulinum toxin type A considers advances in facial analysis, injection techniques, and avoidance and management of complications.
Use of botulinum toxin has evolved from the upper face to also encompass the lower face, neck, and midface. The Global Aesthetics Consensus Group emphasizes an integrative, diagnostic approach. Injection dosage and placement are based on analysis of target muscles in the context of adjacent ones and associated soft and hard tissues. The indication for selection of botulinum toxin as a primary intervention is that excessive muscular contraction is the primary etiology of the facial disharmony to be addressed. Global Aesthetics Consensus Group recommendations demonstrate a paradigm shift toward neuromodulation rather than paralysis, including lower dosing of the upper face, more frequent combination treatment with hyaluronic acid fillers, and intracutaneous injection where indicated to limit depth and degree of action.
The accumulation of clinical evidence and experience with botulinum toxin has led to refinements in treatment planning and implementation. The Global Aesthetics Consensus Group advocates an etiology-driven, patient-tailored approach, to enable achievement of optimal efficacy and safety in patient populations that are rapidly diversifying with respect to ethnicity, gender, and age.
Therapeutic, V.
Url:
DOI: 10.1097/01.prs.0000475758.63709.23
PubMed: 26910696
PubMed Central: 5242214
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PMC:5242214Le document en format XML
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Trindade De Almeida</name></author><author><name sortKey="Wu, Yan" sort="Wu, Yan" uniqKey="Wu Y" first="Yan" last="Wu">Yan Wu</name></author><author><name sortKey="Vieira Braz, Andre" sort="Vieira Braz, Andre" uniqKey="Vieira Braz A" first="André" last="Vieira Braz">André Vieira Braz</name></author><author><name sortKey="Fagien, Steven" sort="Fagien, Steven" uniqKey="Fagien S" first="Steven" last="Fagien">Steven Fagien</name></author><author><name sortKey="Goodman, Greg J" sort="Goodman, Greg J" uniqKey="Goodman G" first="Greg J." last="Goodman">Greg J. Goodman</name></author><author><name sortKey="Monheit, Gary" sort="Monheit, Gary" uniqKey="Monheit G" first="Gary" last="Monheit">Gary Monheit</name></author><author><name sortKey="Raspaldo, Herve" sort="Raspaldo, Herve" uniqKey="Raspaldo H" first="Hervé" last="Raspaldo">Hervé Raspaldo</name></author></analytic><series><title level="j">Plastic and Reconstructive Surgery</title><idno type="ISSN">0032-1052</idno><idno type="eISSN">1529-4242</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age Factors</term><term>Aged</term><term>Botulinum Toxins, Type A (adverse effects)</term><term>Botulinum Toxins, Type A (therapeutic use)</term><term>Consensus</term><term>Cosmetic Techniques (standards)</term><term>Evidence-Based Medicine</term><term>Female</term><term>Humans</term><term>Injections, Subcutaneous</term><term>Male</term><term>Middle Aged</term><term>Neurotoxins (administration & dosage)</term><term>Neurotoxins (adverse effects)</term><term>Patient Satisfaction (statistics & numerical data)</term><term>Practice Guidelines as Topic</term><term>Rejuvenation (physiology)</term><term>Risk Assessment</term><term>Skin Aging (drug effects)</term><term>Treatment Outcome</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Consensus</term><term>Facteurs de l'âge</term><term>Femelle</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Injections sous-cutanées</term><term>Mâle</term><term>Médecine factuelle</term><term>Neurotoxines (administration et posologie)</term><term>Neurotoxines (effets indésirables)</term><term>Rajeunissement (physiologie)</term><term>Résultat thérapeutique</term><term>Satisfaction du patient ()</term><term>Sujet âgé</term><term>Techniques cosmétiques (normes)</term><term>Toxines botuliniques de type A (effets indésirables)</term><term>Toxines botuliniques de type A (usage thérapeutique)</term><term>Vieillissement de la peau ()</term><term>Évaluation des risques</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Neurotoxins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Botulinum Toxins, Type A</term><term>Neurotoxins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Botulinum Toxins, Type A</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Neurotoxines</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Skin Aging</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Neurotoxines</term><term>Toxines botuliniques de type A</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Techniques cosmétiques</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Rajeunissement</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Rejuvenation</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Cosmetic Techniques</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Patient Satisfaction</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Toxines botuliniques de type A</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Age Factors</term><term>Aged</term><term>Consensus</term><term>Evidence-Based Medicine</term><term>Female</term><term>Humans</term><term>Injections, Subcutaneous</term><term>Male</term><term>Middle Aged</term><term>Practice Guidelines as Topic</term><term>Risk Assessment</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Consensus</term><term>Facteurs de l'âge</term><term>Femelle</term><term>Guides de bonnes pratiques cliniques comme sujet</term><term>Humains</term><term>Injections sous-cutanées</term><term>Mâle</term><term>Médecine factuelle</term><term>Résultat thérapeutique</term><term>Satisfaction du patient</term><term>Sujet âgé</term><term>Vieillissement de la peau</term><term>Évaluation des risques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background:</title><p>Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide, with a high rate of efficacy and patient satisfaction.</p></sec><sec><title>Methods:</title><p>A multinational, multidisciplinary group of plastic surgeons and dermatologists convened the Global Aesthetics Consensus Group to develop updated consensus recommendations with a worldwide perspective for botulinum toxin and hyaluronic acid fillers. This publication on botulinum toxin type A considers advances in facial analysis, injection techniques, and avoidance and management of complications.</p></sec><sec><title>Results:</title><p>Use of botulinum toxin has evolved from the upper face to also encompass the lower face, neck, and midface. The Global Aesthetics Consensus Group emphasizes an integrative, diagnostic approach. Injection dosage and placement are based on analysis of target muscles in the context of adjacent ones and associated soft and hard tissues. The indication for selection of botulinum toxin as a primary intervention is that excessive muscular contraction is the primary etiology of the facial disharmony to be addressed. Global Aesthetics Consensus Group recommendations demonstrate a paradigm shift toward neuromodulation rather than paralysis, including lower dosing of the upper face, more frequent combination treatment with hyaluronic acid fillers, and intracutaneous injection where indicated to limit depth and degree of action.</p></sec><sec><title>Conclusions:</title><p>The accumulation of clinical evidence and experience with botulinum toxin has led to refinements in treatment planning and implementation. The Global Aesthetics Consensus Group advocates an etiology-driven, patient-tailored approach, to enable achievement of optimal efficacy and safety in patient populations that are rapidly diversifying with respect to ethnicity, gender, and age.</p></sec><sec><title>CLINCAL QUESTION/LEVEL OF EVIDENCE:</title><p>Therapeutic, V.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Mohindru, A" uniqKey="Mohindru A">A Mohindru</name></author><author><name sortKey="Bulloch, S" uniqKey="Bulloch S">S Bulloch</name></author><author><name sortKey="Kronfeld, N" uniqKey="Kronfeld N">N Kronfeld</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carruthers, Jd" uniqKey="Carruthers J">JD Carruthers</name></author><author><name sortKey="Glogau, Rg" uniqKey="Glogau R">RG Glogau</name></author><author><name sortKey="Blitzer, A" uniqKey="Blitzer A">A Blitzer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raspaldo, H" uniqKey="Raspaldo H">H Raspaldo</name></author><author><name sortKey="Baspeyras, M" uniqKey="Baspeyras M">M Baspeyras</name></author><author><name sortKey="Bellity, P" uniqKey="Bellity P">P Bellity</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raspaldo, H" uniqKey="Raspaldo H">H Raspaldo</name></author><author><name sortKey="Niforos, Fr" uniqKey="Niforos F">FR Niforos</name></author><author><name sortKey="Gassia, V" uniqKey="Gassia V">V Gassia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carruthers, J" uniqKey="Carruthers J">J Carruthers</name></author><author><name sortKey="Fournier, N" uniqKey="Fournier N">N Fournier</name></author><author><name sortKey="Kerscher, M" uniqKey="Kerscher M">M Kerscher</name></author><author><name sortKey="Ruiz Avila, J" uniqKey="Ruiz Avila J">J Ruiz-Avila</name></author><author><name sortKey="Trindade De Almeida, Ar" uniqKey="Trindade De Almeida A">AR Trindade de Almeida</name></author><author><name sortKey="Kaeuper, G" uniqKey="Kaeuper G">G Kaeuper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sundaram, H" uniqKey="Sundaram H">H Sundaram</name></author><author><name sortKey="Liew, S" uniqKey="Liew S">S Liew</name></author><author><name sortKey="Signorini, M" uniqKey="Signorini M">M Signorini</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Jj" uniqKey="Chen J">JJ Chen</name></author><author><name sortKey="Dashtipour, K" uniqKey="Dashtipour K">K Dashtipour</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alam, M" uniqKey="Alam M">M Alam</name></author><author><name sortKey="Dover, Js" uniqKey="Dover J">JS Dover</name></author><author><name sortKey="Arndt, Ka" uniqKey="Arndt K">KA Arndt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alam, M" uniqKey="Alam M">M Alam</name></author><author><name sortKey="Bolotin, D" uniqKey="Bolotin D">D Bolotin</name></author><author><name sortKey="Carruthers, J" uniqKey="Carruthers J">J Carruthers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hexsel, Dm" uniqKey="Hexsel D">DM Hexsel</name></author><author><name sortKey="De Almeida, At" uniqKey="De Almeida A">AT De Almeida</name></author><author><name sortKey="Rutowitsch, M" uniqKey="Rutowitsch M">M Rutowitsch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trindade De Almeida, Ar" uniqKey="Trindade De Almeida A">AR Trindade De Almeida</name></author><author><name sortKey="Secco, Lc" uniqKey="Secco L">LC Secco</name></author><author><name sortKey="Carruthers, A" 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I">I Havermann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goodman, Gj" uniqKey="Goodman G">GJ Goodman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brin, Mf" uniqKey="Brin M">MF Brin</name></author><author><name sortKey="Boodhoo, Ti" uniqKey="Boodhoo T">TI Boodhoo</name></author><author><name sortKey="Pogoda, Jm" uniqKey="Pogoda J">JM Pogoda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Naumann, M" uniqKey="Naumann M">M Naumann</name></author><author><name sortKey="Jankovic, J" uniqKey="Jankovic J">J Jankovic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cavallini, M" uniqKey="Cavallini M">M Cavallini</name></author><author><name sortKey="Cirillo, P" uniqKey="Cirillo P">P Cirillo</name></author><author><name sortKey="Fundar, Sp" uniqKey="Fundar S">SP Fundarò</name></author></analytic></biblStruct><biblStruct><analytic><author><name 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