Global Aesthetics Consensus: Botulinum Toxin Type A—Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications
Identifieur interne : 002B37 ( Pmc/Curation ); précédent : 002B36; suivant : 002B38Global Aesthetics Consensus: Botulinum Toxin Type A—Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications
Auteurs : Hema Sundaram ; Massimo Signorini ; Steven Liew ; Ada R. Trindade De Almeida ; Yan Wu ; André Vieira Braz ; Steven Fagien ; Greg J. Goodman ; Gary Monheit ; Hervé RaspaldoSource :
- Plastic and Reconstructive Surgery [ 0032-1052 ] ; 2016.
Abstract
Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide, with a high rate of efficacy and patient satisfaction.
A multinational, multidisciplinary group of plastic surgeons and dermatologists convened the Global Aesthetics Consensus Group to develop updated consensus recommendations with a worldwide perspective for botulinum toxin and hyaluronic acid fillers. This publication on botulinum toxin type A considers advances in facial analysis, injection techniques, and avoidance and management of complications.
Use of botulinum toxin has evolved from the upper face to also encompass the lower face, neck, and midface. The Global Aesthetics Consensus Group emphasizes an integrative, diagnostic approach. Injection dosage and placement are based on analysis of target muscles in the context of adjacent ones and associated soft and hard tissues. The indication for selection of botulinum toxin as a primary intervention is that excessive muscular contraction is the primary etiology of the facial disharmony to be addressed. Global Aesthetics Consensus Group recommendations demonstrate a paradigm shift toward neuromodulation rather than paralysis, including lower dosing of the upper face, more frequent combination treatment with hyaluronic acid fillers, and intracutaneous injection where indicated to limit depth and degree of action.
The accumulation of clinical evidence and experience with botulinum toxin has led to refinements in treatment planning and implementation. The Global Aesthetics Consensus Group advocates an etiology-driven, patient-tailored approach, to enable achievement of optimal efficacy and safety in patient populations that are rapidly diversifying with respect to ethnicity, gender, and age.
Therapeutic, V.
Url:
DOI: 10.1097/01.prs.0000475758.63709.23
PubMed: 26910696
PubMed Central: 5242214
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<author><name sortKey="Signorini, Massimo" sort="Signorini, Massimo" uniqKey="Signorini M" first="Massimo" last="Signorini">Massimo Signorini</name>
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<author><name sortKey="Liew, Steven" sort="Liew, Steven" uniqKey="Liew S" first="Steven" last="Liew">Steven Liew</name>
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<author><name sortKey="Trindade De Almeida, Ada R" sort="Trindade De Almeida, Ada R" uniqKey="Trindade De Almeida A" first="Ada R." last="Trindade De Almeida">Ada R. Trindade De Almeida</name>
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<author><name sortKey="Fagien, Steven" sort="Fagien, Steven" uniqKey="Fagien S" first="Steven" last="Fagien">Steven Fagien</name>
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<author><name sortKey="Goodman, Greg J" sort="Goodman, Greg J" uniqKey="Goodman G" first="Greg J." last="Goodman">Greg J. Goodman</name>
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<author><name sortKey="Monheit, Gary" sort="Monheit, Gary" uniqKey="Monheit G" first="Gary" last="Monheit">Gary Monheit</name>
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<author><name sortKey="Raspaldo, Herve" sort="Raspaldo, Herve" uniqKey="Raspaldo H" first="Hervé" last="Raspaldo">Hervé Raspaldo</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Global Aesthetics Consensus: Botulinum Toxin Type A—Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications</title>
<author><name sortKey="Sundaram, Hema" sort="Sundaram, Hema" uniqKey="Sundaram H" first="Hema" last="Sundaram">Hema Sundaram</name>
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<author><name sortKey="Signorini, Massimo" sort="Signorini, Massimo" uniqKey="Signorini M" first="Massimo" last="Signorini">Massimo Signorini</name>
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<author><name sortKey="Liew, Steven" sort="Liew, Steven" uniqKey="Liew S" first="Steven" last="Liew">Steven Liew</name>
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<author><name sortKey="Trindade De Almeida, Ada R" sort="Trindade De Almeida, Ada R" uniqKey="Trindade De Almeida A" first="Ada R." last="Trindade De Almeida">Ada R. Trindade De Almeida</name>
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<author><name sortKey="Wu, Yan" sort="Wu, Yan" uniqKey="Wu Y" first="Yan" last="Wu">Yan Wu</name>
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<author><name sortKey="Vieira Braz, Andre" sort="Vieira Braz, Andre" uniqKey="Vieira Braz A" first="André" last="Vieira Braz">André Vieira Braz</name>
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<author><name sortKey="Fagien, Steven" sort="Fagien, Steven" uniqKey="Fagien S" first="Steven" last="Fagien">Steven Fagien</name>
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<author><name sortKey="Goodman, Greg J" sort="Goodman, Greg J" uniqKey="Goodman G" first="Greg J." last="Goodman">Greg J. Goodman</name>
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<author><name sortKey="Monheit, Gary" sort="Monheit, Gary" uniqKey="Monheit G" first="Gary" last="Monheit">Gary Monheit</name>
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<author><name sortKey="Raspaldo, Herve" sort="Raspaldo, Herve" uniqKey="Raspaldo H" first="Hervé" last="Raspaldo">Hervé Raspaldo</name>
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<series><title level="j">Plastic and Reconstructive Surgery</title>
<idno type="ISSN">0032-1052</idno>
<idno type="eISSN">1529-4242</idno>
<imprint><date when="2016">2016</date>
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<front><div type="abstract" xml:lang="en"><sec><title>Background:</title>
<p>Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide, with a high rate of efficacy and patient satisfaction.</p>
</sec>
<sec><title>Methods:</title>
<p>A multinational, multidisciplinary group of plastic surgeons and dermatologists convened the Global Aesthetics Consensus Group to develop updated consensus recommendations with a worldwide perspective for botulinum toxin and hyaluronic acid fillers. This publication on botulinum toxin type A considers advances in facial analysis, injection techniques, and avoidance and management of complications.</p>
</sec>
<sec><title>Results:</title>
<p>Use of botulinum toxin has evolved from the upper face to also encompass the lower face, neck, and midface. The Global Aesthetics Consensus Group emphasizes an integrative, diagnostic approach. Injection dosage and placement are based on analysis of target muscles in the context of adjacent ones and associated soft and hard tissues. The indication for selection of botulinum toxin as a primary intervention is that excessive muscular contraction is the primary etiology of the facial disharmony to be addressed. Global Aesthetics Consensus Group recommendations demonstrate a paradigm shift toward neuromodulation rather than paralysis, including lower dosing of the upper face, more frequent combination treatment with hyaluronic acid fillers, and intracutaneous injection where indicated to limit depth and degree of action.</p>
</sec>
<sec><title>Conclusions:</title>
<p>The accumulation of clinical evidence and experience with botulinum toxin has led to refinements in treatment planning and implementation. The Global Aesthetics Consensus Group advocates an etiology-driven, patient-tailored approach, to enable achievement of optimal efficacy and safety in patient populations that are rapidly diversifying with respect to ethnicity, gender, and age.</p>
</sec>
<sec><title>CLINCAL QUESTION/LEVEL OF EVIDENCE:</title>
<p>Therapeutic, V.</p>
</sec>
</div>
</front>
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</TEI>
<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Plast Reconstr Surg</journal-id>
<journal-id journal-id-type="iso-abbrev">Plast. Reconstr. Surg</journal-id>
<journal-id journal-id-type="publisher-id">PRS</journal-id>
<journal-title-group><journal-title>Plastic and Reconstructive Surgery</journal-title>
</journal-title-group>
<issn pub-type="ppub">0032-1052</issn>
<issn pub-type="epub">1529-4242</issn>
<publisher><publisher-name>Lippincott Williams & Wilkins</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">26910696</article-id>
<article-id pub-id-type="pmc">5242214</article-id>
<article-id pub-id-type="art-access-id">00010</article-id>
<article-id pub-id-type="doi">10.1097/01.prs.0000475758.63709.23</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Cosmetic: Original Articles</subject>
</subj-group>
</article-categories>
<title-group><article-title>Global Aesthetics Consensus: Botulinum Toxin Type A—Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Sundaram</surname>
<given-names>Hema</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Signorini</surname>
<given-names>Massimo</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Liew</surname>
<given-names>Steven</given-names>
</name>
<degrees>M.B.B.S., M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Trindade de Almeida</surname>
<given-names>Ada R.</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Wu</surname>
<given-names>Yan</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Vieira Braz</surname>
<given-names>André</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Fagien</surname>
<given-names>Steven</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Goodman</surname>
<given-names>Greg J.</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Monheit</surname>
<given-names>Gary</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Raspaldo</surname>
<given-names>Hervé</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<aff>Rockville, Md.; Milan, Italy; Sydney, New South Wales, and Carlton, Victoria, Australia; São Paolo and Rio de Janeiro, Brazil; Beijing, China; Boca Raton, Fla.; Seoul, Korea; and Cannes, France</aff>
</contrib-group>
<contrib-group><contrib contrib-type="author"><collab>Global Aesthetics Consensus Group</collab>
</contrib>
</contrib-group>
<author-notes><corresp id="c1">Hema Sundaram, M.D., 11119 Rockville Pike, Suite 205, Rockville, Md. 20852, <email xlink:href="hemasundaram@gmail.com">hemasundaram@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>3</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub"><day>25</day>
<month>2</month>
<year>2016</year>
</pub-date>
<volume>137</volume>
<issue>3</issue>
<fpage>518</fpage>
<lpage>529</lpage>
<history><date date-type="received"><day>2</day>
<month>6</month>
<year>2015</year>
</date>
<date date-type="accepted"><day>21</day>
<month>7</month>
<year>2015</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2016 by the American Society of Plastic Surgeons</copyright-statement>
<copyright-year>2016</copyright-year>
</permissions>
<self-uri xlink:type="simple" xlink:href="prs-137-518e.pdf"></self-uri>
<abstract><sec><title>Background:</title>
<p>Botulinum toxin type A injection remains the leading nonsurgical cosmetic procedure worldwide, with a high rate of efficacy and patient satisfaction.</p>
</sec>
<sec><title>Methods:</title>
<p>A multinational, multidisciplinary group of plastic surgeons and dermatologists convened the Global Aesthetics Consensus Group to develop updated consensus recommendations with a worldwide perspective for botulinum toxin and hyaluronic acid fillers. This publication on botulinum toxin type A considers advances in facial analysis, injection techniques, and avoidance and management of complications.</p>
</sec>
<sec><title>Results:</title>
<p>Use of botulinum toxin has evolved from the upper face to also encompass the lower face, neck, and midface. The Global Aesthetics Consensus Group emphasizes an integrative, diagnostic approach. Injection dosage and placement are based on analysis of target muscles in the context of adjacent ones and associated soft and hard tissues. The indication for selection of botulinum toxin as a primary intervention is that excessive muscular contraction is the primary etiology of the facial disharmony to be addressed. Global Aesthetics Consensus Group recommendations demonstrate a paradigm shift toward neuromodulation rather than paralysis, including lower dosing of the upper face, more frequent combination treatment with hyaluronic acid fillers, and intracutaneous injection where indicated to limit depth and degree of action.</p>
</sec>
<sec><title>Conclusions:</title>
<p>The accumulation of clinical evidence and experience with botulinum toxin has led to refinements in treatment planning and implementation. The Global Aesthetics Consensus Group advocates an etiology-driven, patient-tailored approach, to enable achievement of optimal efficacy and safety in patient populations that are rapidly diversifying with respect to ethnicity, gender, and age.</p>
</sec>
<sec><title>CLINCAL QUESTION/LEVEL OF EVIDENCE:</title>
<p>Therapeutic, V.</p>
</sec>
</abstract>
<custom-meta-group><custom-meta><meta-name>STATUS</meta-name>
<meta-value>ONLINE-ONLY</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>
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