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Neandertal and Denisovan DNA from Pleistocene sediments.

Identifieur interne : 000747 ( Main/Merge ); précédent : 000746; suivant : 000748

Neandertal and Denisovan DNA from Pleistocene sediments.

Auteurs : Viviane Slon [Allemagne] ; Charlotte Hopfe [Allemagne] ; Clemens L. Wei [Allemagne] ; Fabrizio Mafessoni [Allemagne] ; Marco De La Rasilla [Espagne] ; Carles Lalueza-Fox [Espagne] ; Antonio Rosas [Espagne] ; Marie Soressi [Pays-Bas] ; Monika V. Knul [Royaume-Uni] ; Rebecca Miller [Belgique] ; John R. Stewart [Royaume-Uni] ; Anatoly P. Derevianko [Russie] ; Zenobia Jacobs [Australie] ; Bo Li [Australie] ; Richard G. Roberts [Australie] ; Michael V. Shunkov [Russie] ; Henry De Lumley [France] ; Christian Perrenoud [France] ; Ivan Guši [Croatie] ; Željko Ku An [Croatie] ; Pavao Rudan [Croatie] ; Ayinuer Aximu-Petri [Allemagne] ; Elena Essel [Allemagne] ; Sarah Nagel [Allemagne] ; Birgit Nickel [Allemagne] ; Anna Schmidt [Allemagne] ; Kay Prüfer [Allemagne] ; Janet Kelso [Allemagne] ; Hernán A. Burbano [Allemagne] ; Svante P Bo [Allemagne] ; Matthias Meyer [Allemagne]

Source :

RBID : pubmed:28450384

Abstract

Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.

DOI: 10.1126/science.aam9695
PubMed: 28450384

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pubmed:28450384

Le document en format XML

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<name sortKey="Miller, Rebecca" sort="Miller, Rebecca" uniqKey="Miller R" first="Rebecca" last="Miller">Rebecca Miller</name>
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<name sortKey="Derevianko, Anatoly P" sort="Derevianko, Anatoly P" uniqKey="Derevianko A" first="Anatoly P" last="Derevianko">Anatoly P. Derevianko</name>
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<name sortKey="Li, Bo" sort="Li, Bo" uniqKey="Li B" first="Bo" last="Li">Bo Li</name>
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<nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation>
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<name sortKey="Roberts, Richard G" sort="Roberts, Richard G" uniqKey="Roberts R" first="Richard G" last="Roberts">Richard G. Roberts</name>
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<nlm:affiliation>Centre for Archaeological Science, School of Earth and Environmental Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.</nlm:affiliation>
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<name sortKey="Shunkov, Michael V" sort="Shunkov, Michael V" uniqKey="Shunkov M" first="Michael V" last="Shunkov">Michael V. Shunkov</name>
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<name sortKey="De Lumley, Henry" sort="De Lumley, Henry" uniqKey="De Lumley H" first="Henry" last="De Lumley">Henry De Lumley</name>
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<nlm:affiliation>Centre Européen de Recherches Préhistoriques de Tautavel, 66720 Tautavel, France.</nlm:affiliation>
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<name sortKey="Gusi, Ivan" sort="Gusi, Ivan" uniqKey="Gusi I" first="Ivan" last="Guši">Ivan Guši</name>
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<name sortKey="Ku An, Zeljko" sort="Ku An, Zeljko" uniqKey="Ku An Z" first="Željko" last="Ku An">Željko Ku An</name>
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<name sortKey="Rudan, Pavao" sort="Rudan, Pavao" uniqKey="Rudan P" first="Pavao" last="Rudan">Pavao Rudan</name>
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<name sortKey="Aximu Petri, Ayinuer" sort="Aximu Petri, Ayinuer" uniqKey="Aximu Petri A" first="Ayinuer" last="Aximu-Petri">Ayinuer Aximu-Petri</name>
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<nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation>
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<name sortKey="Essel, Elena" sort="Essel, Elena" uniqKey="Essel E" first="Elena" last="Essel">Elena Essel</name>
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<name sortKey="Nagel, Sarah" sort="Nagel, Sarah" uniqKey="Nagel S" first="Sarah" last="Nagel">Sarah Nagel</name>
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<name sortKey="Nickel, Birgit" sort="Nickel, Birgit" uniqKey="Nickel B" first="Birgit" last="Nickel">Birgit Nickel</name>
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<name sortKey="Schmidt, Anna" sort="Schmidt, Anna" uniqKey="Schmidt A" first="Anna" last="Schmidt">Anna Schmidt</name>
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<name sortKey="Prufer, Kay" sort="Prufer, Kay" uniqKey="Prufer K" first="Kay" last="Prüfer">Kay Prüfer</name>
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<name sortKey="Kelso, Janet" sort="Kelso, Janet" uniqKey="Kelso J" first="Janet" last="Kelso">Janet Kelso</name>
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<name sortKey="Burbano, Hernan A" sort="Burbano, Hernan A" uniqKey="Burbano H" first="Hernán A" last="Burbano">Hernán A. Burbano</name>
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<name sortKey="P Bo, Svante" sort="P Bo, Svante" uniqKey="P Bo S" first="Svante" last="P Bo">Svante P Bo</name>
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<name sortKey="Meyer, Matthias" sort="Meyer, Matthias" uniqKey="Meyer M" first="Matthias" last="Meyer">Matthias Meyer</name>
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<nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</nlm:affiliation>
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<country xml:lang="fr">Allemagne</country>
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<country xml:lang="fr">Allemagne</country>
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<name sortKey="Aximu Petri, Ayinuer" sort="Aximu Petri, Ayinuer" uniqKey="Aximu Petri A" first="Ayinuer" last="Aximu-Petri">Ayinuer Aximu-Petri</name>
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<nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
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<country xml:lang="fr">Allemagne</country>
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<name sortKey="Schmidt, Anna" sort="Schmidt, Anna" uniqKey="Schmidt A" first="Anna" last="Schmidt">Anna Schmidt</name>
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<nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
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<name sortKey="Prufer, Kay" sort="Prufer, Kay" uniqKey="Prufer K" first="Kay" last="Prüfer">Kay Prüfer</name>
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<nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig</wicri:regionArea>
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<name sortKey="Kelso, Janet" sort="Kelso, Janet" uniqKey="Kelso J" first="Janet" last="Kelso">Janet Kelso</name>
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<nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
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<name sortKey="Burbano, Hernan A" sort="Burbano, Hernan A" uniqKey="Burbano H" first="Hernán A" last="Burbano">Hernán A. Burbano</name>
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<nlm:affiliation>Research Group for Ancient Genomics and Evolution, Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.</nlm:affiliation>
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<name sortKey="P Bo, Svante" sort="P Bo, Svante" uniqKey="P Bo S" first="Svante" last="P Bo">Svante P Bo</name>
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<nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
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<author>
<name sortKey="Meyer, Matthias" sort="Meyer, Matthias" uniqKey="Meyer M" first="Matthias" last="Meyer">Matthias Meyer</name>
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<nlm:affiliation>Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany. viviane_slon@eva.mpg.de mmeyer@eva.mpg.de.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
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<series>
<title level="j">Science (New York, N.Y.)</title>
<idno type="eISSN">1095-9203</idno>
<imprint>
<date when="2017" type="published">2017</date>
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<front>
<div type="abstract" xml:lang="en">Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA, we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples, we detected Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave, we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility of detecting the presence of hominin groups at sites and in areas where no skeletal remains are found.</div>
</front>
</TEI>
</record>

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