Antiretroviral Drug-Related Liver Mortality Among HIV-Positive Persons in the Absence of Hepatitis B or C Virus Coinfection: The Data Collection on Adverse Events of Anti-HIV Drugs Study
Identifieur interne : 005465 ( Main/Exploration ); précédent : 005464; suivant : 005466Antiretroviral Drug-Related Liver Mortality Among HIV-Positive Persons in the Absence of Hepatitis B or C Virus Coinfection: The Data Collection on Adverse Events of Anti-HIV Drugs Study
Auteurs : Helen Kovari [Suisse] ; Caroline A. Sabin [Royaume-Uni] ; Bruno Ledergerber [Suisse] ; Lene Ryom [Danemark] ; Signe W. Worm [Danemark] ; Colette Smith [Royaume-Uni] ; Andrew Phillips [Royaume-Uni] ; Peter Reiss [Pays-Bas] ; Eric Fontas [France] ; Kathy Petoumenos [Australie] ; Stéphane De Wit [Belgique] ; Philippe Morlat [France] ; Jens D. Lundgren [Danemark] ; Rainer Weber [Suisse]Source :
- Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America [ 1058-4838 ] ; 2012.
Abstract
In a large prospective multicohort study 22 910 human immunodeficiency virus–positive participants without hepatitis B or C virus coinfection were followed for 114 478 patient-years. The incidence of liver-related death was low at 0.10 per 1000 patient-years. Liverrelated mortality due to antiretroviral drug-related toxicity was rare.
Url:
DOI: 10.1093/cid/cis919
PubMed: 23090925
PubMed Central: 3582358
Affiliations:
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Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antiretroviral Drug-Related Liver Mortality Among HIV-Positive Persons in the Absence of Hepatitis B or C Virus Coinfection: The Data Collection on Adverse Events of Anti-HIV Drugs Study</title>
<author><name sortKey="Kovari, Helen" sort="Kovari, Helen" uniqKey="Kovari H" first="Helen" last="Kovari">Helen Kovari</name>
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<country xml:lang="fr">Danemark</country>
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<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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,<institution>Academic Medical Center</institution>
,<addr-line>Amsterdam</addr-line>
,<country>The Netherlands</country>
</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Fontas, Eric" sort="Fontas, Eric" uniqKey="Fontas E" first="Eric" last="Fontas">Eric Fontas</name>
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,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="Petoumenos, Kathy" sort="Petoumenos, Kathy" uniqKey="Petoumenos K" first="Kathy" last="Petoumenos">Kathy Petoumenos</name>
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,<institution>University of New South Wales</institution>
,<addr-line>Sydney</addr-line>
,<country>Australia</country>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<author><name sortKey="De Wit, Stephane" sort="De Wit, Stephane" uniqKey="De Wit S" first="Stéphane" last="De Wit">Stéphane De Wit</name>
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<front><div type="abstract" xml:lang="en"><p>In a large prospective multicohort study 22 910 human immunodeficiency virus–positive participants without hepatitis B or C virus coinfection were followed for 114 478 patient-years. The incidence of liver-related death was low at 0.10 per 1000 patient-years. Liverrelated mortality due to antiretroviral drug-related toxicity was rare.</p>
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