The effect of QRS duration on cardiac resynchronization therapy in patients with a narrow QRS complex: a subgroup analysis of the EchoCRT trial.
Identifieur interne : 002736 ( Main/Exploration ); précédent : 002735; suivant : 002737The effect of QRS duration on cardiac resynchronization therapy in patients with a narrow QRS complex: a subgroup analysis of the EchoCRT trial.
Auteurs : Jan Steffel [Suisse] ; Michele Robertson [Royaume-Uni] ; Jagmeet P. Singh [États-Unis] ; William T. Abraham [États-Unis] ; Jeroen J. Bax [Pays-Bas] ; Jeffrey S. Borer [États-Unis] ; Kenneth Dickstein [Norvège] ; Ian Ford [Royaume-Uni] ; John Gorcsan [États-Unis] ; Daniel Gras [France] ; Henry Krum [Australie] ; Peter Sogaard [Danemark] ; Johannes Holzmeister [Suisse] ; Josep Brugada [Espagne] ; Frank Ruschitzka [Oman]Source :
- European heart journal [ 1522-9645 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Défaillance cardiaque (), Défaillance cardiaque (physiopathologie), Estimation de Kaplan-Meier, Femelle, Humains, Mâle, Thérapie de resynchronisation cardiaque, Troubles du rythme cardiaque (), Troubles du rythme cardiaque (physiopathologie), Échec thérapeutique, Électrocardiographie.
- MESH :
English descriptors
- KwdEn :
- MESH :
- physiopathology : Arrhythmias, Cardiac, Heart Failure.
- therapy : Arrhythmias, Cardiac, Heart Failure.
- Cardiac Resynchronization Therapy, Electrocardiography, Female, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Treatment Failure.
Abstract
In EchoCRT, a randomized trial evaluating the effect of cardiac resynchronization therapy (CRT) in patients with a QRS duration of <130 ms and echocardiographic evidence of left ventricular dyssynchrony, the primary outcome occurred more frequently in the CRT when compared with the control group. According to current heart failure guidelines, CRT is recommended in patients with a QRS duration of ≥120 ms. However, there is some ambiguity from clinical trial data regarding the benefit of patients with a QRS duration of 120-130 ms.
DOI: 10.1093/eurheartj/ehv242
PubMed: 26009595
Affiliations:
- Australie, Danemark, Espagne, France, Norvège, Oman, Pays-Bas, Royaume-Uni, Suisse, États-Unis
- Hollande-Méridionale, Jutland du Nord, Massachusetts, Ohio, Pays de la Loire, Pennsylvanie, Écosse, État de New York
- Aalborg, Glasgow, Leyde, Nantes, Pittsburgh
- Université d'Aalborg, Université de Glasgow, Université de Pittsburgh
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Heart Center Zurich, Zurich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Cardiology, Heart Failure Clinic and Transplantation, University Heart Center Zurich, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author><author><name sortKey="Robertson, Michele" sort="Robertson, Michele" uniqKey="Robertson M" first="Michele" last="Robertson">Michele Robertson</name><affiliation wicri:level="4"><nlm:affiliation>Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Robertson Centre for Biostatistics, University of Glasgow, Glasgow</wicri:regionArea><orgName type="university">Université de Glasgow</orgName><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Singh, Jagmeet P" sort="Singh, Jagmeet P" uniqKey="Singh 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Stavanger</wicri:regionArea><wicri:noRegion>Stavanger</wicri:noRegion></affiliation></author><author><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name><affiliation wicri:level="4"><nlm:affiliation>Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Robertson Centre for Biostatistics, University of Glasgow, Glasgow</wicri:regionArea><orgName type="university">Université de Glasgow</orgName><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Gorcsan, John" sort="Gorcsan, John" uniqKey="Gorcsan J" first="John" last="Gorcsan">John Gorcsan</name><affiliation wicri:level="4"><nlm:affiliation>University of Pittsburgh, Pittsburgh, PA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Pittsburgh, Pittsburgh, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Gras, Daniel" sort="Gras, Daniel" uniqKey="Gras D" first="Daniel" last="Gras">Daniel Gras</name><affiliation wicri:level="3"><nlm:affiliation>Nouvelles Cliniques Nantaises, Nantes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Nouvelles Cliniques Nantaises, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Krum, Henry" sort="Krum, Henry" uniqKey="Krum H" first="Henry" last="Krum">Henry Krum</name><affiliation wicri:level="1"><nlm:affiliation>Monash Centre of Cardiovascular Research and Education in Therapeutics, Melbourne, VIC, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Monash Centre of Cardiovascular Research and Education in Therapeutics, Melbourne, VIC</wicri:regionArea><wicri:noRegion>VIC</wicri:noRegion></affiliation></author><author><name sortKey="Sogaard, Peter" sort="Sogaard, Peter" uniqKey="Sogaard P" first="Peter" last="Sogaard">Peter Sogaard</name><affiliation wicri:level="4"><nlm:affiliation>Aalborg University, Aalborg, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Aalborg University, Aalborg</wicri:regionArea><orgName type="university">Université d'Aalborg</orgName><placeName><settlement type="city">Aalborg</settlement><region nuts="2" type="region">Jutland du Nord</region></placeName></affiliation></author><author><name sortKey="Holzmeister, Johannes" sort="Holzmeister, Johannes" uniqKey="Holzmeister J" first="Johannes" last="Holzmeister">Johannes Holzmeister</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Heart Failure Clinic and Transplantation, University Heart Center Zurich, Zurich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Cardiology, Heart Failure Clinic and Transplantation, University Heart Center Zurich, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author><author><name sortKey="Brugada, Josep" sort="Brugada, Josep" uniqKey="Brugada J" first="Josep" last="Brugada">Josep Brugada</name><affiliation wicri:level="1"><nlm:affiliation>Cardiology Department, Thorax Institute, Hospital Clinic, University of Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Cardiology Department, Thorax Institute, Hospital Clinic, University of Barcelona</wicri:regionArea><wicri:noRegion>University of Barcelona</wicri:noRegion></affiliation></author><author><name sortKey="Ruschitzka, Frank" sort="Ruschitzka, Frank" uniqKey="Ruschitzka F" first="Frank" last="Ruschitzka">Frank Ruschitzka</name><affiliation wicri:level="1"><nlm:affiliation>Department of Cardiology, Heart Failure Clinic and Transplantation, University Heart Center Zurich, Zurich, Switzerland frank.ruschitzka@googlemail.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>Department of Cardiology, Heart Failure Clinic and Transplantation, University Heart Center Zurich, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author></analytic><series><title level="j">European heart journal</title><idno type="eISSN">1522-9645</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Arrhythmias, Cardiac (physiopathology)</term><term>Arrhythmias, Cardiac (therapy)</term><term>Cardiac Resynchronization Therapy</term><term>Electrocardiography</term><term>Female</term><term>Heart Failure (physiopathology)</term><term>Heart Failure (therapy)</term><term>Humans</term><term>Kaplan-Meier Estimate</term><term>Male</term><term>Middle Aged</term><term>Treatment Failure</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Défaillance cardiaque ()</term><term>Défaillance cardiaque (physiopathologie)</term><term>Estimation de Kaplan-Meier</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Thérapie de resynchronisation cardiaque</term><term>Troubles du rythme cardiaque ()</term><term>Troubles du rythme cardiaque (physiopathologie)</term><term>Échec thérapeutique</term><term>Électrocardiographie</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Défaillance cardiaque</term><term>Troubles du rythme cardiaque</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Arrhythmias, Cardiac</term><term>Heart Failure</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Arrhythmias, Cardiac</term><term>Heart Failure</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cardiac Resynchronization Therapy</term><term>Electrocardiography</term><term>Female</term><term>Humans</term><term>Kaplan-Meier Estimate</term><term>Male</term><term>Middle Aged</term><term>Treatment Failure</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Défaillance cardiaque</term><term>Estimation de Kaplan-Meier</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Thérapie de resynchronisation cardiaque</term><term>Troubles du rythme cardiaque</term><term>Échec thérapeutique</term><term>Électrocardiographie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In EchoCRT, a randomized trial evaluating the effect of cardiac resynchronization therapy (CRT) in patients with a QRS duration of <130 ms and echocardiographic evidence of left ventricular dyssynchrony, the primary outcome occurred more frequently in the CRT when compared with the control group. According to current heart failure guidelines, CRT is recommended in patients with a QRS duration of ≥120 ms. However, there is some ambiguity from clinical trial data regarding the benefit of patients with a QRS duration of 120-130 ms.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Danemark</li><li>Espagne</li><li>France</li><li>Norvège</li><li>Oman</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li><li>États-Unis</li></country><region><li>Hollande-Méridionale</li><li>Jutland du Nord</li><li>Massachusetts</li><li>Ohio</li><li>Pays de la Loire</li><li>Pennsylvanie</li><li>Écosse</li><li>État de New York</li></region><settlement><li>Aalborg</li><li>Glasgow</li><li>Leyde</li><li>Nantes</li><li>Pittsburgh</li></settlement><orgName><li>Université d'Aalborg</li><li>Université de Glasgow</li><li>Université de Pittsburgh</li></orgName></list><tree><country name="Suisse"><noRegion><name sortKey="Steffel, Jan" sort="Steffel, Jan" uniqKey="Steffel J" first="Jan" last="Steffel">Jan Steffel</name></noRegion><name sortKey="Holzmeister, Johannes" sort="Holzmeister, Johannes" uniqKey="Holzmeister J" first="Johannes" last="Holzmeister">Johannes Holzmeister</name></country><country name="Royaume-Uni"><region name="Écosse"><name sortKey="Robertson, Michele" sort="Robertson, Michele" uniqKey="Robertson M" first="Michele" last="Robertson">Michele Robertson</name></region><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Singh, Jagmeet P" sort="Singh, Jagmeet P" uniqKey="Singh J" first="Jagmeet P" last="Singh">Jagmeet P. Singh</name></region><name sortKey="Abraham, William T" sort="Abraham, William T" uniqKey="Abraham W" first="William T" last="Abraham">William T. Abraham</name><name sortKey="Borer, Jeffrey S" sort="Borer, Jeffrey S" uniqKey="Borer J" first="Jeffrey S" last="Borer">Jeffrey S. Borer</name><name sortKey="Gorcsan, John" sort="Gorcsan, John" uniqKey="Gorcsan J" first="John" last="Gorcsan">John Gorcsan</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Bax, Jeroen J" sort="Bax, Jeroen J" uniqKey="Bax J" first="Jeroen J" last="Bax">Jeroen J. Bax</name></region></country><country name="Norvège"><noRegion><name sortKey="Dickstein, Kenneth" sort="Dickstein, Kenneth" uniqKey="Dickstein K" first="Kenneth" last="Dickstein">Kenneth Dickstein</name></noRegion></country><country name="France"><region name="Pays de la Loire"><name sortKey="Gras, Daniel" sort="Gras, Daniel" uniqKey="Gras D" first="Daniel" last="Gras">Daniel Gras</name></region></country><country name="Australie"><noRegion><name sortKey="Krum, Henry" sort="Krum, Henry" uniqKey="Krum H" first="Henry" last="Krum">Henry Krum</name></noRegion></country><country name="Danemark"><region name="Jutland du Nord"><name sortKey="Sogaard, Peter" sort="Sogaard, Peter" uniqKey="Sogaard P" first="Peter" last="Sogaard">Peter Sogaard</name></region></country><country name="Espagne"><noRegion><name sortKey="Brugada, Josep" sort="Brugada, Josep" uniqKey="Brugada J" first="Josep" last="Brugada">Josep Brugada</name></noRegion></country><country name="Oman"><noRegion><name sortKey="Ruschitzka, Frank" sort="Ruschitzka, Frank" uniqKey="Ruschitzka F" first="Frank" last="Ruschitzka">Frank Ruschitzka</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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