Diversity in cell motility reveals the dynamic nature of the formation of zebrafish taste sensory organs.
Identifieur interne : 002079 ( Main/Exploration ); précédent : 002078; suivant : 002080Diversity in cell motility reveals the dynamic nature of the formation of zebrafish taste sensory organs.
Auteurs : Marina Soulika [France] ; Anna-Lila Kaushik [France] ; Benjamin Mathieu [France] ; Raquel Lourenço [France] ; Anna Z. Komisarczuk [Australie] ; Sebastian Alejo Romano [France] ; Adrien Jouary [France] ; Alicia Lardennois [France] ; Nicolas Tissot [France] ; Shinji Okada [Japon] ; Keiko Abe [Japon] ; Thomas S. Becker [Australie] ; Marika Kapsimali [France]Source :
- Development (Cambridge, England) [ 1477-9129 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Calicules gustatifs (croissance et développement), Calicules gustatifs (cytologie), Danio zébré (physiologie), Différenciation cellulaire, Facteurs de transcription à motif basique hélice-boucle-hélice (métabolisme), Larve (cytologie), Larve (métabolisme), Lignage cellulaire, Mouvement cellulaire, Numération cellulaire, Organogenèse, Protéines de poisson-zèbre (métabolisme), Sérotonine (métabolisme), Éléments activateurs (génétique) (génétique).
- MESH :
- croissance et développement : Calicules gustatifs.
- cytologie : Calicules gustatifs, Larve.
- génétique : Éléments activateurs (génétique).
- métabolisme : Facteurs de transcription à motif basique hélice-boucle-hélice, Larve, Protéines de poisson-zèbre, Sérotonine.
- physiologie : Danio zébré.
- Animaux, Différenciation cellulaire, Lignage cellulaire, Mouvement cellulaire, Numération cellulaire, Organogenèse.
English descriptors
- KwdEn :
- Animals, Basic Helix-Loop-Helix Transcription Factors (metabolism), Cell Count, Cell Differentiation, Cell Lineage, Cell Movement, Enhancer Elements, Genetic (genetics), Larva (cytology), Larva (metabolism), Organogenesis, Serotonin (metabolism), Taste Buds (cytology), Taste Buds (growth & development), Zebrafish (physiology), Zebrafish Proteins (metabolism).
- MESH :
- chemical , metabolism : Basic Helix-Loop-Helix Transcription Factors, Serotonin, Zebrafish Proteins.
- cytology : Larva, Taste Buds.
- genetics : Enhancer Elements, Genetic.
- growth & development : Taste Buds.
- metabolism : Larva.
- physiology : Zebrafish.
- Animals, Cell Count, Cell Differentiation, Cell Lineage, Cell Movement, Organogenesis.
Abstract
Taste buds are sensory organs in jawed vertebrates, composed of distinct cell types that detect and transduce specific taste qualities. Taste bud cells differentiate from oropharyngeal epithelial progenitors, which are localized mainly in proximity to the forming organs. Despite recent progress in elucidating the molecular interactions required for taste bud cell development and function, the cell behavior underlying the organ assembly is poorly defined. Here, we used time-lapse imaging to observe the formation of taste buds in live zebrafish larvae. We found that tg(fgf8a.dr17)-expressing cells form taste buds and get rearranged within the forming organs. In addition, differentiating cells move from the epithelium to the forming organs and can be displaced between developing organs. During organ formation, tg(fgf8a.dr17) and type II taste bud cells are displaced in random, directed or confined mode relative to the taste bud they join or by which they are maintained. Finally, ascl1a activity in the 5-HT/type III cell is required to direct and maintain tg(fgf8a.dr17)-expressing cells into the taste bud. We propose that diversity in displacement modes of differentiating cells acts as a key mechanism for the highly dynamic process of taste bud assembly.
DOI: 10.1242/dev.134817
PubMed: 27122167
Affiliations:
- Australie, France, Japon
- Nouvelle-Galles du Sud, Région de Kantō, Île-de-France
- Paris, Sydney, Tokyo
- Université de Sydney, Université de Tokyo
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001D24
- to stream PubMed, to step Curation: 001D00
- to stream PubMed, to step Checkpoint: 001D00
- to stream Ncbi, to step Merge: 003482
- to stream Ncbi, to step Curation: 003482
- to stream Ncbi, to step Checkpoint: 003482
- to stream Main, to step Merge: 002078
- to stream Main, to step Curation: 002079
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Diversity in cell motility reveals the dynamic nature of the formation of zebrafish taste sensory organs.</title><author><name sortKey="Soulika, Marina" sort="Soulika, Marina" uniqKey="Soulika M" first="Marina" last="Soulika">Marina Soulika</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Kaushik, Anna Lila" sort="Kaushik, Anna Lila" uniqKey="Kaushik A" first="Anna-Lila" last="Kaushik">Anna-Lila Kaushik</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Mathieu, Benjamin" sort="Mathieu, Benjamin" uniqKey="Mathieu B" first="Benjamin" last="Mathieu">Benjamin Mathieu</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Lourenco, Raquel" sort="Lourenco, Raquel" uniqKey="Lourenco R" first="Raquel" last="Lourenço">Raquel Lourenço</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Komisarczuk, Anna Z" sort="Komisarczuk, Anna Z" uniqKey="Komisarczuk A" first="Anna Z" last="Komisarczuk">Anna Z. Komisarczuk</name><affiliation wicri:level="4"><nlm:affiliation>Developmental Neurobiology and Genomics, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW 2050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Neurobiology and Genomics, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW 2050</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Romano, Sebastian Alejo" sort="Romano, Sebastian Alejo" uniqKey="Romano S" first="Sebastian Alejo" last="Romano">Sebastian Alejo Romano</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Jouary, Adrien" sort="Jouary, Adrien" uniqKey="Jouary A" first="Adrien" last="Jouary">Adrien Jouary</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Lardennois, Alicia" sort="Lardennois, Alicia" uniqKey="Lardennois A" first="Alicia" last="Lardennois">Alicia Lardennois</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Tissot, Nicolas" sort="Tissot, Nicolas" uniqKey="Tissot N" first="Nicolas" last="Tissot">Nicolas Tissot</name><affiliation wicri:level="1"><nlm:affiliation>Institut Jacques Monod, CNRS UMR7592, University Paris Diderot, 75013 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut Jacques Monod, CNRS UMR7592, University Paris Diderot, 75013 Paris</wicri:regionArea><wicri:noRegion>75013 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Okada, Shinji" sort="Okada, Shinji" uniqKey="Okada S" first="Shinji" last="Okada">Shinji Okada</name><affiliation wicri:level="4"><nlm:affiliation>Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Abe, Keiko" sort="Abe, Keiko" uniqKey="Abe K" first="Keiko" last="Abe">Keiko Abe</name><affiliation wicri:level="4"><nlm:affiliation>Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Becker, Thomas S" sort="Becker, Thomas S" uniqKey="Becker T" first="Thomas S" last="Becker">Thomas S. Becker</name><affiliation wicri:level="4"><nlm:affiliation>Developmental Neurobiology and Genomics, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW 2050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Neurobiology and Genomics, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW 2050</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Kapsimali, Marika" sort="Kapsimali, Marika" uniqKey="Kapsimali M" first="Marika" last="Kapsimali">Marika Kapsimali</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France marika.kapsimali@ens.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27122167</idno><idno type="pmid">27122167</idno><idno type="doi">10.1242/dev.134817</idno><idno type="wicri:Area/PubMed/Corpus">001D24</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001D24</idno><idno type="wicri:Area/PubMed/Curation">001D00</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001D00</idno><idno type="wicri:Area/PubMed/Checkpoint">001D00</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001D00</idno><idno type="wicri:Area/Ncbi/Merge">003482</idno><idno type="wicri:Area/Ncbi/Curation">003482</idno><idno type="wicri:Area/Ncbi/Checkpoint">003482</idno><idno type="wicri:Area/Main/Merge">002078</idno><idno type="wicri:Area/Main/Curation">002079</idno><idno type="wicri:Area/Main/Exploration">002079</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Diversity in cell motility reveals the dynamic nature of the formation of zebrafish taste sensory organs.</title><author><name sortKey="Soulika, Marina" sort="Soulika, Marina" uniqKey="Soulika M" first="Marina" last="Soulika">Marina Soulika</name><affiliation wicri:level="3"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Kaushik, Anna Lila" sort="Kaushik, Anna Lila" uniqKey="Kaushik A" first="Anna-Lila" last="Kaushik">Anna-Lila Kaushik</name><affiliation wicri:level="3"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Mathieu, Benjamin" sort="Mathieu, Benjamin" uniqKey="Mathieu B" first="Benjamin" last="Mathieu">Benjamin Mathieu</name><affiliation wicri:level="3"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lourenco, Raquel" sort="Lourenco, Raquel" uniqKey="Lourenco R" first="Raquel" last="Lourenço">Raquel Lourenço</name><affiliation wicri:level="3"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Komisarczuk, Anna Z" sort="Komisarczuk, Anna Z" uniqKey="Komisarczuk A" first="Anna Z" last="Komisarczuk">Anna Z. Komisarczuk</name><affiliation wicri:level="4"><nlm:affiliation>Developmental Neurobiology and Genomics, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW 2050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Neurobiology and Genomics, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW 2050</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Romano, Sebastian Alejo" sort="Romano, Sebastian Alejo" uniqKey="Romano S" first="Sebastian Alejo" last="Romano">Sebastian Alejo Romano</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Jouary, Adrien" sort="Jouary, Adrien" uniqKey="Jouary A" first="Adrien" last="Jouary">Adrien Jouary</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Lardennois, Alicia" sort="Lardennois, Alicia" uniqKey="Lardennois A" first="Alicia" last="Lardennois">Alicia Lardennois</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Tissot, Nicolas" sort="Tissot, Nicolas" uniqKey="Tissot N" first="Nicolas" last="Tissot">Nicolas Tissot</name><affiliation wicri:level="1"><nlm:affiliation>Institut Jacques Monod, CNRS UMR7592, University Paris Diderot, 75013 Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut Jacques Monod, CNRS UMR7592, University Paris Diderot, 75013 Paris</wicri:regionArea><wicri:noRegion>75013 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author><author><name sortKey="Okada, Shinji" sort="Okada, Shinji" uniqKey="Okada S" first="Shinji" last="Okada">Shinji Okada</name><affiliation wicri:level="4"><nlm:affiliation>Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Abe, Keiko" sort="Abe, Keiko" uniqKey="Abe K" first="Keiko" last="Abe">Keiko Abe</name><affiliation wicri:level="4"><nlm:affiliation>Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Becker, Thomas S" sort="Becker, Thomas S" uniqKey="Becker T" first="Thomas S" last="Becker">Thomas S. Becker</name><affiliation wicri:level="4"><nlm:affiliation>Developmental Neurobiology and Genomics, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW 2050, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Developmental Neurobiology and Genomics, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW 2050</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Kapsimali, Marika" sort="Kapsimali, Marika" uniqKey="Kapsimali M" first="Marika" last="Kapsimali">Marika Kapsimali</name><affiliation wicri:level="1"><nlm:affiliation>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris, France marika.kapsimali@ens.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>IBENS, Ecole Normale Supérieure, CNRS UMR8197, INSERM U1024, 75230 Paris</wicri:regionArea><wicri:noRegion>75230 Paris</wicri:noRegion><placeName><settlement type="city">Paris</settlement><region type="région" nuts="2">Île-de-France</region></placeName></affiliation></author></analytic><series><title level="j">Development (Cambridge, England)</title><idno type="eISSN">1477-9129</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Basic Helix-Loop-Helix Transcription Factors (metabolism)</term><term>Cell Count</term><term>Cell Differentiation</term><term>Cell Lineage</term><term>Cell Movement</term><term>Enhancer Elements, Genetic (genetics)</term><term>Larva (cytology)</term><term>Larva (metabolism)</term><term>Organogenesis</term><term>Serotonin (metabolism)</term><term>Taste Buds (cytology)</term><term>Taste Buds (growth & development)</term><term>Zebrafish (physiology)</term><term>Zebrafish Proteins (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Calicules gustatifs (croissance et développement)</term><term>Calicules gustatifs (cytologie)</term><term>Danio zébré (physiologie)</term><term>Différenciation cellulaire</term><term>Facteurs de transcription à motif basique hélice-boucle-hélice (métabolisme)</term><term>Larve (cytologie)</term><term>Larve (métabolisme)</term><term>Lignage cellulaire</term><term>Mouvement cellulaire</term><term>Numération cellulaire</term><term>Organogenèse</term><term>Protéines de poisson-zèbre (métabolisme)</term><term>Sérotonine (métabolisme)</term><term>Éléments activateurs (génétique) (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Basic Helix-Loop-Helix Transcription Factors</term><term>Serotonin</term><term>Zebrafish Proteins</term></keywords><keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Calicules gustatifs</term></keywords><keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Calicules gustatifs</term><term>Larve</term></keywords><keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Larva</term><term>Taste Buds</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Enhancer Elements, Genetic</term></keywords><keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Taste Buds</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Éléments activateurs (génétique)</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Larva</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Facteurs de transcription à motif basique hélice-boucle-hélice</term><term>Larve</term><term>Protéines de poisson-zèbre</term><term>Sérotonine</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Danio zébré</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Zebrafish</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Count</term><term>Cell Differentiation</term><term>Cell Lineage</term><term>Cell Movement</term><term>Organogenesis</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Différenciation cellulaire</term><term>Lignage cellulaire</term><term>Mouvement cellulaire</term><term>Numération cellulaire</term><term>Organogenèse</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Taste buds are sensory organs in jawed vertebrates, composed of distinct cell types that detect and transduce specific taste qualities. Taste bud cells differentiate from oropharyngeal epithelial progenitors, which are localized mainly in proximity to the forming organs. Despite recent progress in elucidating the molecular interactions required for taste bud cell development and function, the cell behavior underlying the organ assembly is poorly defined. Here, we used time-lapse imaging to observe the formation of taste buds in live zebrafish larvae. We found that tg(fgf8a.dr17)-expressing cells form taste buds and get rearranged within the forming organs. In addition, differentiating cells move from the epithelium to the forming organs and can be displaced between developing organs. During organ formation, tg(fgf8a.dr17) and type II taste bud cells are displaced in random, directed or confined mode relative to the taste bud they join or by which they are maintained. Finally, ascl1a activity in the 5-HT/type III cell is required to direct and maintain tg(fgf8a.dr17)-expressing cells into the taste bud. We propose that diversity in displacement modes of differentiating cells acts as a key mechanism for the highly dynamic process of taste bud assembly.</div></front></TEI><affiliations><list><country><li>Australie</li><li>France</li><li>Japon</li></country><region><li>Nouvelle-Galles du Sud</li><li>Région de Kantō</li><li>Île-de-France</li></region><settlement><li>Paris</li><li>Sydney</li><li>Tokyo</li></settlement><orgName><li>Université de Sydney</li><li>Université de Tokyo</li></orgName></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Soulika, Marina" sort="Soulika, Marina" uniqKey="Soulika M" first="Marina" last="Soulika">Marina Soulika</name></region><name sortKey="Jouary, Adrien" sort="Jouary, Adrien" uniqKey="Jouary A" first="Adrien" last="Jouary">Adrien Jouary</name><name sortKey="Kapsimali, Marika" sort="Kapsimali, Marika" uniqKey="Kapsimali M" first="Marika" last="Kapsimali">Marika Kapsimali</name><name sortKey="Kaushik, Anna Lila" sort="Kaushik, Anna Lila" uniqKey="Kaushik A" first="Anna-Lila" last="Kaushik">Anna-Lila Kaushik</name><name sortKey="Lardennois, Alicia" sort="Lardennois, Alicia" uniqKey="Lardennois A" first="Alicia" last="Lardennois">Alicia Lardennois</name><name sortKey="Lourenco, Raquel" sort="Lourenco, Raquel" uniqKey="Lourenco R" first="Raquel" last="Lourenço">Raquel Lourenço</name><name sortKey="Mathieu, Benjamin" sort="Mathieu, Benjamin" uniqKey="Mathieu B" first="Benjamin" last="Mathieu">Benjamin Mathieu</name><name sortKey="Romano, Sebastian Alejo" sort="Romano, Sebastian Alejo" uniqKey="Romano S" first="Sebastian Alejo" last="Romano">Sebastian Alejo Romano</name><name sortKey="Tissot, Nicolas" sort="Tissot, Nicolas" uniqKey="Tissot N" first="Nicolas" last="Tissot">Nicolas Tissot</name></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Komisarczuk, Anna Z" sort="Komisarczuk, Anna Z" uniqKey="Komisarczuk A" first="Anna Z" last="Komisarczuk">Anna Z. Komisarczuk</name></region><name sortKey="Becker, Thomas S" sort="Becker, Thomas S" uniqKey="Becker T" first="Thomas S" last="Becker">Thomas S. Becker</name></country><country name="Japon"><region name="Région de Kantō"><name sortKey="Okada, Shinji" sort="Okada, Shinji" uniqKey="Okada S" first="Shinji" last="Okada">Shinji Okada</name></region><name sortKey="Abe, Keiko" sort="Abe, Keiko" uniqKey="Abe K" first="Keiko" last="Abe">Keiko Abe</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002079 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002079 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:27122167
|texte= Diversity in cell motility reveals the dynamic nature of the formation of zebrafish taste sensory organs.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27122167" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |