AustralieFrV1, Main, Exploration, bibRecord, 000491

Rational design of rabies vaccine formulation for enhanced stability.

Identifieur interne : 000491 ( Main/Exploration ); précédent : 000490; suivant : 000492

Rational design of rabies vaccine formulation for enhanced stability.

Auteurs : Veysel Kayser [États-Unis] ; Alain Françon [France] ; Hervé Pinton [France] ; Jean-François Saluzzo [France] ; Bernhardt L. Trout [États-Unis]

Source :

Turkish journal of medical sciences [ 1300-0144 ] ; 2017.

RBID : pubmed:28618756

Abstract

Vaccines are often lyophilized in order to retain their stability and efficacy for a longer period of time. However, the same lyophilization process may also cause a major degradation of the vaccine, especially during early phases of manufacturing, leading to a loss of potency of the product. Many viral diseases, such as rabies, are acute and fatal unless the vaccine is administered prior to exposure or the onset of symptoms in the case of postexposure treatment.

DOI: 10.3906/sag-1610-82
PubMed: 28618756

Affiliations:

Le document en format XML

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Rational design of rabies vaccine formulation for enhanced stability.

Rational design of rabies vaccine formulation for enhanced stability.

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Abstract

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