Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)
Identifieur interne : 006C62 ( Main/Curation ); précédent : 006C61; suivant : 006C63Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)
Auteurs : P. Bertuccio [Italie] ; C. La Vecchia [Italie] ; D. T. Silverman [États-Unis] ; G. M. Petersen [États-Unis] ; P. M. Bracci [États-Unis] ; E. Negri [Italie] ; D. Li [États-Unis] ; H. A. Risch [États-Unis] ; S. H. Olson [États-Unis] ; S. Gallinger [Canada] ; A. B. Miller [Canada] ; H. B. Bueno-De-Mesquita [Pays-Bas] ; R. Talamini [Italie] ; J. Polesel [Italie] ; P. Ghadirian [Canada] ; P. A. Baghurst [Australie] ; W. Zatonski [Pologne] ; E. T. Fontham [États-Unis] ; W. R. Bamlet [États-Unis] ; E. A. Holly [États-Unis] ; E. Lucenteforte [Pays-Bas] ; M. Hassan [États-Unis] ; H. Yu [États-Unis] ; R. C. Kurtz [États-Unis] ; M. Cotterchio [Canada] ; J. Su [États-Unis] ; P. Maisonneuve [Italie] ; E. J. Duell [Espagne] ; C. Bosetti [Italie] ; P. Boffetta [France, États-Unis]Source :
- Annals of oncology [ 0923-7534 ] ; 2011.
Descripteurs français
- Pascal (Inist)
- Wicri :
English descriptors
- KwdEn :
Abstract
Background: Cigarette smoking is the best-characterized risk factor for pancreatic cancer. However, data are limited for other tobacco smoking products and smokeless tobacco. Materials and methods: We conducted a pooled analysis of cigar and pipe smoking and smokeless tobacco use and risk of pancreatic cancer using data from 11 case-control studies (6056 cases and 11 338 controls) within the International Pancreatic Cancer Case-Control Consortium (PanC4). Pooled odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated by unconditional multiple logistic regression models adjusted for study center and selected covariates. Results: Compared with never tobacco users, the OR for cigar-only smokers was 1.6 (95% CI: 1.2-2.3), i.e. comparable to that of cigarette-only smokers (OR 1.5; 95% CI 1.4-1.6). The OR was 1.1 (95% CI 0.69-1.6) for pipe-only smokers. There was some evidence of increasing risk with increasing amount of cigar smoked per day (OR 1.82 for ≥ 10 grams of tobacco), although not with duration. The OR for ever smokeless tobacco users as compared with never tobacco users was 0.98 (95% CI 0.75-1.3). Conclusion: This collaborative analysis provides evidence that cigar smoking is associated with an excess risk of pancreatic cancer, while no significant association emerged for pipe smoking and smokeless tobacco use.
Url:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001B15
- to stream PascalFrancis, to step Curation: Pour aller vers cette notice dans l'étape Curation :004429
- to stream PascalFrancis, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001C70
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :007121
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001732
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :001592
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002379
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000961
- to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :000961
- to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000961
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :006574
Links to Exploration step
Pascal:11-0317098Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)</title><author><name sortKey="Bertuccio, P" sort="Bertuccio, P" uniqKey="Bertuccio P" first="P." last="Bertuccio">P. Bertuccio</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Occupational Health, Section of Medical Statistics, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="La Vecchia, C" sort="La Vecchia, C" uniqKey="La Vecchia C" first="C." last="La Vecchia">C. La Vecchia</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Occupational Health, Section of Medical Statistics, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Silverman, D T" sort="Silverman, D T" uniqKey="Silverman D" first="D. T." last="Silverman">D. T. Silverman</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Cancer Institute</s1><s2>Bethesda</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Cancer Institute</wicri:noRegion></affiliation></author><author><name sortKey="Petersen, G M" sort="Petersen, G M" uniqKey="Petersen G" first="G. M." last="Petersen">G. M. Petersen</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Mayo Clinic</s1><s2>Rochester</s2><s3>USA</s3><sZ>4 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Mayo Clinic</wicri:noRegion></affiliation></author><author><name sortKey="Bracci, P M" sort="Bracci, P M" uniqKey="Bracci P" first="P. M." last="Bracci">P. M. Bracci</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>University of California</s1><s2>San Francisco</s2><s3>USA</s3><sZ>5 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Negri, E" sort="Negri, E" uniqKey="Negri E" first="E." last="Negri">E. Negri</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Li, D" sort="Li, D" uniqKey="Li D" first="D." last="Li">D. Li</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>The University of Texas M.D Anderson Cancer Center</s1><s2>Houston</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Risch, H A" sort="Risch, H A" uniqKey="Risch H" first="H. A." last="Risch">H. A. Risch</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Epidemiology and Public Health, Yale University School of Medicine</s1><s2>New Haven</s2><s3>USA</s3><sZ>8 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Haven</wicri:noRegion></affiliation></author><author><name sortKey="Olson, S H" sort="Olson, S H" uniqKey="Olson S" first="S. H." last="Olson">S. H. Olson</name><affiliation wicri:level="2"><inist:fA14 i1="08"><s1>Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center</s1><s2>New York</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Gallinger, S" sort="Gallinger, S" uniqKey="Gallinger S" first="S." last="Gallinger">S. Gallinger</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Toronto General Hospital</s1><s3>CAN</s3><sZ>10 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Toronto General Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Miller, A B" sort="Miller, A B" uniqKey="Miller A" first="A. B." last="Miller">A. B. Miller</name><affiliation wicri:level="4"><inist:fA14 i1="10"><s1>Dalla Lana School of Public Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>11 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Bueno De Mesquita, H B" sort="Bueno De Mesquita, H B" uniqKey="Bueno De Mesquita H" first="H. B." last="Bueno-De-Mesquita">H. B. Bueno-De-Mesquita</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>National Institute for Public Health and the Environment (RIVM)</s1><s2>Bilthoven</s2><s3>NLD</s3><sZ>12 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>National Institute for Public Health and the Environment (RIVM)</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU)</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>12 aut.</sZ><sZ>21 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Talamini, R" sort="Talamini, R" uniqKey="Talamini R" first="R." last="Talamini">R. Talamini</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO)</s1><s2>Aviano</s2><s3>ITA</s3><sZ>13 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Polesel, J" sort="Polesel, J" uniqKey="Polesel J" first="J." last="Polesel">J. Polesel</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO)</s1><s2>Aviano</s2><s3>ITA</s3><sZ>13 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Ghadirian, P" sort="Ghadirian, P" uniqKey="Ghadirian P" first="P." last="Ghadirian">P. Ghadirian</name><affiliation wicri:level="3"><inist:fA14 i1="14"><s1>Epidemiology Research Unit, Research Centre (CRCHUM)</s1><s2>Montreal</s2><s3>CAN</s3><sZ>15 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Baghurst, P A" sort="Baghurst, P A" uniqKey="Baghurst P" first="P. A." last="Baghurst">P. A. Baghurst</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Public Health, Women's and Children's Hospital</s1><s2>Adelaide</s2><s3>AUS</s3><sZ>16 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author><author><name sortKey="Zatonski, W" sort="Zatonski, W" uniqKey="Zatonski W" first="W." last="Zatonski">W. Zatonski</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Cancer Center & Institute of Oncology</s1><s2>Warsaw</s2><s3>POL</s3><sZ>17 aut.</sZ></inist:fA14><country>Pologne</country><wicri:noRegion>Cancer Center & Institute of Oncology</wicri:noRegion></affiliation></author><author><name sortKey="Fontham, E T" sort="Fontham, E T" uniqKey="Fontham E" first="E. T." last="Fontham">E. T. Fontham</name><affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Louisiana State University, School of Public Health</s1><s2>New Orleans</s2><s3>USA</s3><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Orleans</wicri:noRegion></affiliation></author><author><name sortKey="Bamlet, W R" sort="Bamlet, W R" uniqKey="Bamlet W" first="W. R." last="Bamlet">W. R. Bamlet</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Mayo Clinic</s1><s2>Rochester</s2><s3>USA</s3><sZ>4 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Mayo Clinic</wicri:noRegion></affiliation></author><author><name sortKey="Holly, E A" sort="Holly, E A" uniqKey="Holly E" first="E. A." last="Holly">E. A. Holly</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>University of California</s1><s2>San Francisco</s2><s3>USA</s3><sZ>5 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Lucenteforte, E" sort="Lucenteforte, E" uniqKey="Lucenteforte E" first="E." last="Lucenteforte">E. Lucenteforte</name><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU)</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>12 aut.</sZ><sZ>21 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Hassan, M" sort="Hassan, M" uniqKey="Hassan M" first="M." last="Hassan">M. Hassan</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>The University of Texas M.D Anderson Cancer Center</s1><s2>Houston</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Yu, H" sort="Yu, H" uniqKey="Yu H" first="H." last="Yu">H. Yu</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Epidemiology and Public Health, Yale University School of Medicine</s1><s2>New Haven</s2><s3>USA</s3><sZ>8 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Haven</wicri:noRegion></affiliation></author><author><name sortKey="Kurtz, R C" sort="Kurtz, R C" uniqKey="Kurtz R" first="R. C." last="Kurtz">R. C. Kurtz</name><affiliation wicri:level="2"><inist:fA14 i1="18"><s1>Department of Medicine, Memorial Sloan-Kettering Cancer Center</s1><s2>New York</s2><s3>USA</s3><sZ>24 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Cotterchio, M" sort="Cotterchio, M" uniqKey="Cotterchio M" first="M." last="Cotterchio">M. Cotterchio</name><affiliation wicri:level="4"><inist:fA14 i1="10"><s1>Dalla Lana School of Public Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>11 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Cancer Care Ontario</s1><s2>Toronto</s2><s3>CAN</s3><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Cancer Care Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Su, J" sort="Su, J" uniqKey="Su J" first="J." last="Su">J. Su</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Cancer Institute</s1><s2>Bethesda</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Cancer Institute</wicri:noRegion></affiliation></author><author><name sortKey="Maisonneuve, P" sort="Maisonneuve, P" uniqKey="Maisonneuve P" first="P." last="Maisonneuve">P. Maisonneuve</name><affiliation wicri:level="3"><inist:fA14 i1="20"><s1>European Institute of Oncology</s1><s2>Milan</s2><s3>ITA</s3><sZ>27 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Duell, E J" sort="Duell, E J" uniqKey="Duell E" first="E. J." last="Duell">E. J. Duell</name><affiliation wicri:level="3"><inist:fA14 i1="21"><s1>Catalan Institute of Oncology (ICO)</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>28 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bosetti, C" sort="Bosetti, C" uniqKey="Bosetti C" first="C." last="Bosetti">C. Bosetti</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Boffetta, P" sort="Boffetta, P" uniqKey="Boffetta P" first="P." last="Boffetta">P. Boffetta</name><affiliation wicri:level="3"><inist:fA14 i1="22"><s1>International Prevention Research Institute</s1><s2>Lyon</s2><s3>FRA</s3><sZ>30 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="23"><s1>The Tisch Cancer Institute, Mount Sinai School of Medicine</s1><s2>New York</s2><s3>USA</s3><sZ>30 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">11-0317098</idno><date when="2011">2011</date><idno type="stanalyst">PASCAL 11-0317098 INIST</idno><idno type="RBID">Pascal:11-0317098</idno><idno type="wicri:Area/PascalFrancis/Corpus">001B15</idno><idno type="wicri:Area/PascalFrancis/Curation">004429</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001C70</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">001C70</idno><idno type="wicri:doubleKey">0923-7534:2011:Bertuccio P:cigar:and:pipe</idno><idno type="wicri:Area/Main/Merge">007121</idno><idno type="wicri:source">PMC</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139985</idno><idno type="RBID">PMC:3139985</idno><idno type="wicri:Area/Pmc/Corpus">001732</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001732</idno><idno type="wicri:Area/Pmc/Curation">001592</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001592</idno><idno type="wicri:Area/Pmc/Checkpoint">002379</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002379</idno><idno type="wicri:Area/Ncbi/Merge">000961</idno><idno type="wicri:Area/Ncbi/Curation">000961</idno><idno type="wicri:Area/Ncbi/Checkpoint">000961</idno><idno type="wicri:doubleKey">0923-7534:2011:Bertuccio P:cigar:and:pipe</idno><idno type="wicri:Area/Main/Merge">006574</idno><idno type="wicri:Area/Main/Curation">006C62</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)</title><author><name sortKey="Bertuccio, P" sort="Bertuccio, P" uniqKey="Bertuccio P" first="P." last="Bertuccio">P. Bertuccio</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Occupational Health, Section of Medical Statistics, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="La Vecchia, C" sort="La Vecchia, C" uniqKey="La Vecchia C" first="C." last="La Vecchia">C. La Vecchia</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Occupational Health, Section of Medical Statistics, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Silverman, D T" sort="Silverman, D T" uniqKey="Silverman D" first="D. T." last="Silverman">D. T. Silverman</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Cancer Institute</s1><s2>Bethesda</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Cancer Institute</wicri:noRegion></affiliation></author><author><name sortKey="Petersen, G M" sort="Petersen, G M" uniqKey="Petersen G" first="G. M." last="Petersen">G. M. Petersen</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Mayo Clinic</s1><s2>Rochester</s2><s3>USA</s3><sZ>4 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Mayo Clinic</wicri:noRegion></affiliation></author><author><name sortKey="Bracci, P M" sort="Bracci, P M" uniqKey="Bracci P" first="P. M." last="Bracci">P. M. Bracci</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>University of California</s1><s2>San Francisco</s2><s3>USA</s3><sZ>5 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Negri, E" sort="Negri, E" uniqKey="Negri E" first="E." last="Negri">E. Negri</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Li, D" sort="Li, D" uniqKey="Li D" first="D." last="Li">D. Li</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>The University of Texas M.D Anderson Cancer Center</s1><s2>Houston</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Risch, H A" sort="Risch, H A" uniqKey="Risch H" first="H. A." last="Risch">H. A. Risch</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Epidemiology and Public Health, Yale University School of Medicine</s1><s2>New Haven</s2><s3>USA</s3><sZ>8 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Haven</wicri:noRegion></affiliation></author><author><name sortKey="Olson, S H" sort="Olson, S H" uniqKey="Olson S" first="S. H." last="Olson">S. H. Olson</name><affiliation wicri:level="2"><inist:fA14 i1="08"><s1>Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center</s1><s2>New York</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Gallinger, S" sort="Gallinger, S" uniqKey="Gallinger S" first="S." last="Gallinger">S. Gallinger</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Toronto General Hospital</s1><s3>CAN</s3><sZ>10 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Toronto General Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Miller, A B" sort="Miller, A B" uniqKey="Miller A" first="A. B." last="Miller">A. B. Miller</name><affiliation wicri:level="4"><inist:fA14 i1="10"><s1>Dalla Lana School of Public Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>11 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Bueno De Mesquita, H B" sort="Bueno De Mesquita, H B" uniqKey="Bueno De Mesquita H" first="H. B." last="Bueno-De-Mesquita">H. B. Bueno-De-Mesquita</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>National Institute for Public Health and the Environment (RIVM)</s1><s2>Bilthoven</s2><s3>NLD</s3><sZ>12 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>National Institute for Public Health and the Environment (RIVM)</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU)</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>12 aut.</sZ><sZ>21 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Talamini, R" sort="Talamini, R" uniqKey="Talamini R" first="R." last="Talamini">R. Talamini</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO)</s1><s2>Aviano</s2><s3>ITA</s3><sZ>13 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Polesel, J" sort="Polesel, J" uniqKey="Polesel J" first="J." last="Polesel">J. Polesel</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO)</s1><s2>Aviano</s2><s3>ITA</s3><sZ>13 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Ghadirian, P" sort="Ghadirian, P" uniqKey="Ghadirian P" first="P." last="Ghadirian">P. Ghadirian</name><affiliation wicri:level="3"><inist:fA14 i1="14"><s1>Epidemiology Research Unit, Research Centre (CRCHUM)</s1><s2>Montreal</s2><s3>CAN</s3><sZ>15 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Baghurst, P A" sort="Baghurst, P A" uniqKey="Baghurst P" first="P. A." last="Baghurst">P. A. Baghurst</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Public Health, Women's and Children's Hospital</s1><s2>Adelaide</s2><s3>AUS</s3><sZ>16 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author><author><name sortKey="Zatonski, W" sort="Zatonski, W" uniqKey="Zatonski W" first="W." last="Zatonski">W. Zatonski</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Cancer Center & Institute of Oncology</s1><s2>Warsaw</s2><s3>POL</s3><sZ>17 aut.</sZ></inist:fA14><country>Pologne</country><wicri:noRegion>Cancer Center & Institute of Oncology</wicri:noRegion></affiliation></author><author><name sortKey="Fontham, E T" sort="Fontham, E T" uniqKey="Fontham E" first="E. T." last="Fontham">E. T. Fontham</name><affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Louisiana State University, School of Public Health</s1><s2>New Orleans</s2><s3>USA</s3><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Orleans</wicri:noRegion></affiliation></author><author><name sortKey="Bamlet, W R" sort="Bamlet, W R" uniqKey="Bamlet W" first="W. R." last="Bamlet">W. R. Bamlet</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Mayo Clinic</s1><s2>Rochester</s2><s3>USA</s3><sZ>4 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Mayo Clinic</wicri:noRegion></affiliation></author><author><name sortKey="Holly, E A" sort="Holly, E A" uniqKey="Holly E" first="E. A." last="Holly">E. A. Holly</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>University of California</s1><s2>San Francisco</s2><s3>USA</s3><sZ>5 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Lucenteforte, E" sort="Lucenteforte, E" uniqKey="Lucenteforte E" first="E." last="Lucenteforte">E. Lucenteforte</name><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU)</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>12 aut.</sZ><sZ>21 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Hassan, M" sort="Hassan, M" uniqKey="Hassan M" first="M." last="Hassan">M. Hassan</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>The University of Texas M.D Anderson Cancer Center</s1><s2>Houston</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Yu, H" sort="Yu, H" uniqKey="Yu H" first="H." last="Yu">H. Yu</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Epidemiology and Public Health, Yale University School of Medicine</s1><s2>New Haven</s2><s3>USA</s3><sZ>8 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Haven</wicri:noRegion></affiliation></author><author><name sortKey="Kurtz, R C" sort="Kurtz, R C" uniqKey="Kurtz R" first="R. C." last="Kurtz">R. C. Kurtz</name><affiliation wicri:level="2"><inist:fA14 i1="18"><s1>Department of Medicine, Memorial Sloan-Kettering Cancer Center</s1><s2>New York</s2><s3>USA</s3><sZ>24 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Cotterchio, M" sort="Cotterchio, M" uniqKey="Cotterchio M" first="M." last="Cotterchio">M. Cotterchio</name><affiliation wicri:level="4"><inist:fA14 i1="10"><s1>Dalla Lana School of Public Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>11 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Cancer Care Ontario</s1><s2>Toronto</s2><s3>CAN</s3><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Cancer Care Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Su, J" sort="Su, J" uniqKey="Su J" first="J." last="Su">J. Su</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Cancer Institute</s1><s2>Bethesda</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Cancer Institute</wicri:noRegion></affiliation></author><author><name sortKey="Maisonneuve, P" sort="Maisonneuve, P" uniqKey="Maisonneuve P" first="P." last="Maisonneuve">P. Maisonneuve</name><affiliation wicri:level="3"><inist:fA14 i1="20"><s1>European Institute of Oncology</s1><s2>Milan</s2><s3>ITA</s3><sZ>27 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Duell, E J" sort="Duell, E J" uniqKey="Duell E" first="E. J." last="Duell">E. J. Duell</name><affiliation wicri:level="3"><inist:fA14 i1="21"><s1>Catalan Institute of Oncology (ICO)</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>28 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bosetti, C" sort="Bosetti, C" uniqKey="Bosetti C" first="C." last="Bosetti">C. Bosetti</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Boffetta, P" sort="Boffetta, P" uniqKey="Boffetta P" first="P." last="Boffetta">P. Boffetta</name><affiliation wicri:level="3"><inist:fA14 i1="22"><s1>International Prevention Research Institute</s1><s2>Lyon</s2><s3>FRA</s3><sZ>30 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="23"><s1>The Tisch Cancer Institute, Mount Sinai School of Medicine</s1><s2>New York</s2><s3>USA</s3><sZ>30 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Annals of oncology</title><title level="j" type="abbreviated">Ann. oncol.</title><idno type="ISSN">0923-7534</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Annals of oncology</title><title level="j" type="abbreviated">Ann. oncol.</title><idno type="ISSN">0923-7534</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Analysis</term><term>Case control study</term><term>Cigar</term><term>Human</term><term>International</term><term>Pancreas cancer</term><term>Smokeless tobacco</term><term>Tobacco smoking</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Cigare</term><term>Tabagisme</term><term>Tabac sans fumée</term><term>Cancer du pancréas</term><term>Analyse</term><term>International</term><term>Homme</term><term>Etude cas témoin</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Tabagisme</term><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Cigarette smoking is the best-characterized risk factor for pancreatic cancer. However, data are limited for other tobacco smoking products and smokeless tobacco. Materials and methods: We conducted a pooled analysis of cigar and pipe smoking and smokeless tobacco use and risk of pancreatic cancer using data from 11 case-control studies (6056 cases and 11 338 controls) within the International Pancreatic Cancer Case-Control Consortium (PanC4). Pooled odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated by unconditional multiple logistic regression models adjusted for study center and selected covariates. Results: Compared with never tobacco users, the OR for cigar-only smokers was 1.6 (95% CI: 1.2-2.3), i.e. comparable to that of cigarette-only smokers (OR 1.5; 95% CI 1.4-1.6). The OR was 1.1 (95% CI 0.69-1.6) for pipe-only smokers. There was some evidence of increasing risk with increasing amount of cigar smoked per day (OR 1.82 for ≥ 10 grams of tobacco), although not with duration. The OR for ever smokeless tobacco users as compared with never tobacco users was 0.98 (95% CI 0.75-1.3). Conclusion: This collaborative analysis provides evidence that cigar smoking is associated with an excess risk of pancreatic cancer, while no significant association emerged for pipe smoking and smokeless tobacco use.</div></front></TEI><double idat="0923-7534:2011:Bertuccio P:cigar:and:pipe"><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)</title><author><name sortKey="Bertuccio, P" sort="Bertuccio, P" uniqKey="Bertuccio P" first="P." last="Bertuccio">P. Bertuccio</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Occupational Health, Section of Medical Statistics, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="La Vecchia, C" sort="La Vecchia, C" uniqKey="La Vecchia C" first="C." last="La Vecchia">C. La Vecchia</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Occupational Health, Section of Medical Statistics, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Silverman, D T" sort="Silverman, D T" uniqKey="Silverman D" first="D. T." last="Silverman">D. T. Silverman</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Cancer Institute</s1><s2>Bethesda</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Cancer Institute</wicri:noRegion></affiliation></author><author><name sortKey="Petersen, G M" sort="Petersen, G M" uniqKey="Petersen G" first="G. M." last="Petersen">G. M. Petersen</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Mayo Clinic</s1><s2>Rochester</s2><s3>USA</s3><sZ>4 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Mayo Clinic</wicri:noRegion></affiliation></author><author><name sortKey="Bracci, P M" sort="Bracci, P M" uniqKey="Bracci P" first="P. M." last="Bracci">P. M. Bracci</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>University of California</s1><s2>San Francisco</s2><s3>USA</s3><sZ>5 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Negri, E" sort="Negri, E" uniqKey="Negri E" first="E." last="Negri">E. Negri</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Li, D" sort="Li, D" uniqKey="Li D" first="D." last="Li">D. Li</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>The University of Texas M.D Anderson Cancer Center</s1><s2>Houston</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Risch, H A" sort="Risch, H A" uniqKey="Risch H" first="H. A." last="Risch">H. A. Risch</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Epidemiology and Public Health, Yale University School of Medicine</s1><s2>New Haven</s2><s3>USA</s3><sZ>8 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Haven</wicri:noRegion></affiliation></author><author><name sortKey="Olson, S H" sort="Olson, S H" uniqKey="Olson S" first="S. H." last="Olson">S. H. Olson</name><affiliation wicri:level="2"><inist:fA14 i1="08"><s1>Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center</s1><s2>New York</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Gallinger, S" sort="Gallinger, S" uniqKey="Gallinger S" first="S." last="Gallinger">S. Gallinger</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Toronto General Hospital</s1><s3>CAN</s3><sZ>10 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Toronto General Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Miller, A B" sort="Miller, A B" uniqKey="Miller A" first="A. B." last="Miller">A. B. Miller</name><affiliation wicri:level="4"><inist:fA14 i1="10"><s1>Dalla Lana School of Public Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>11 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Bueno De Mesquita, H B" sort="Bueno De Mesquita, H B" uniqKey="Bueno De Mesquita H" first="H. B." last="Bueno-De-Mesquita">H. B. Bueno-De-Mesquita</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>National Institute for Public Health and the Environment (RIVM)</s1><s2>Bilthoven</s2><s3>NLD</s3><sZ>12 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>National Institute for Public Health and the Environment (RIVM)</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU)</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>12 aut.</sZ><sZ>21 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Talamini, R" sort="Talamini, R" uniqKey="Talamini R" first="R." last="Talamini">R. Talamini</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO)</s1><s2>Aviano</s2><s3>ITA</s3><sZ>13 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Polesel, J" sort="Polesel, J" uniqKey="Polesel J" first="J." last="Polesel">J. Polesel</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO)</s1><s2>Aviano</s2><s3>ITA</s3><sZ>13 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Ghadirian, P" sort="Ghadirian, P" uniqKey="Ghadirian P" first="P." last="Ghadirian">P. Ghadirian</name><affiliation wicri:level="3"><inist:fA14 i1="14"><s1>Epidemiology Research Unit, Research Centre (CRCHUM)</s1><s2>Montreal</s2><s3>CAN</s3><sZ>15 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Baghurst, P A" sort="Baghurst, P A" uniqKey="Baghurst P" first="P. A." last="Baghurst">P. A. Baghurst</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Public Health, Women's and Children's Hospital</s1><s2>Adelaide</s2><s3>AUS</s3><sZ>16 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author><author><name sortKey="Zatonski, W" sort="Zatonski, W" uniqKey="Zatonski W" first="W." last="Zatonski">W. Zatonski</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Cancer Center & Institute of Oncology</s1><s2>Warsaw</s2><s3>POL</s3><sZ>17 aut.</sZ></inist:fA14><country>Pologne</country><wicri:noRegion>Cancer Center & Institute of Oncology</wicri:noRegion></affiliation></author><author><name sortKey="Fontham, E T" sort="Fontham, E T" uniqKey="Fontham E" first="E. T." last="Fontham">E. T. Fontham</name><affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Louisiana State University, School of Public Health</s1><s2>New Orleans</s2><s3>USA</s3><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Orleans</wicri:noRegion></affiliation></author><author><name sortKey="Bamlet, W R" sort="Bamlet, W R" uniqKey="Bamlet W" first="W. R." last="Bamlet">W. R. Bamlet</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Mayo Clinic</s1><s2>Rochester</s2><s3>USA</s3><sZ>4 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Mayo Clinic</wicri:noRegion></affiliation></author><author><name sortKey="Holly, E A" sort="Holly, E A" uniqKey="Holly E" first="E. A." last="Holly">E. A. Holly</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>University of California</s1><s2>San Francisco</s2><s3>USA</s3><sZ>5 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Lucenteforte, E" sort="Lucenteforte, E" uniqKey="Lucenteforte E" first="E." last="Lucenteforte">E. Lucenteforte</name><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU)</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>12 aut.</sZ><sZ>21 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Hassan, M" sort="Hassan, M" uniqKey="Hassan M" first="M." last="Hassan">M. Hassan</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>The University of Texas M.D Anderson Cancer Center</s1><s2>Houston</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Yu, H" sort="Yu, H" uniqKey="Yu H" first="H." last="Yu">H. Yu</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Epidemiology and Public Health, Yale University School of Medicine</s1><s2>New Haven</s2><s3>USA</s3><sZ>8 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Haven</wicri:noRegion></affiliation></author><author><name sortKey="Kurtz, R C" sort="Kurtz, R C" uniqKey="Kurtz R" first="R. C." last="Kurtz">R. C. Kurtz</name><affiliation wicri:level="2"><inist:fA14 i1="18"><s1>Department of Medicine, Memorial Sloan-Kettering Cancer Center</s1><s2>New York</s2><s3>USA</s3><sZ>24 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Cotterchio, M" sort="Cotterchio, M" uniqKey="Cotterchio M" first="M." last="Cotterchio">M. Cotterchio</name><affiliation wicri:level="4"><inist:fA14 i1="10"><s1>Dalla Lana School of Public Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>11 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Cancer Care Ontario</s1><s2>Toronto</s2><s3>CAN</s3><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Cancer Care Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Su, J" sort="Su, J" uniqKey="Su J" first="J." last="Su">J. Su</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Cancer Institute</s1><s2>Bethesda</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Cancer Institute</wicri:noRegion></affiliation></author><author><name sortKey="Maisonneuve, P" sort="Maisonneuve, P" uniqKey="Maisonneuve P" first="P." last="Maisonneuve">P. Maisonneuve</name><affiliation wicri:level="3"><inist:fA14 i1="20"><s1>European Institute of Oncology</s1><s2>Milan</s2><s3>ITA</s3><sZ>27 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Duell, E J" sort="Duell, E J" uniqKey="Duell E" first="E. J." last="Duell">E. J. Duell</name><affiliation wicri:level="3"><inist:fA14 i1="21"><s1>Catalan Institute of Oncology (ICO)</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>28 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bosetti, C" sort="Bosetti, C" uniqKey="Bosetti C" first="C." last="Bosetti">C. Bosetti</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Boffetta, P" sort="Boffetta, P" uniqKey="Boffetta P" first="P." last="Boffetta">P. Boffetta</name><affiliation wicri:level="3"><inist:fA14 i1="22"><s1>International Prevention Research Institute</s1><s2>Lyon</s2><s3>FRA</s3><sZ>30 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="23"><s1>The Tisch Cancer Institute, Mount Sinai School of Medicine</s1><s2>New York</s2><s3>USA</s3><sZ>30 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">11-0317098</idno><date when="2011">2011</date><idno type="stanalyst">PASCAL 11-0317098 INIST</idno><idno type="RBID">Pascal:11-0317098</idno><idno type="wicri:Area/PascalFrancis/Corpus">001B15</idno><idno type="wicri:Area/PascalFrancis/Curation">004429</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001C70</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">001C70</idno><idno type="wicri:doubleKey">0923-7534:2011:Bertuccio P:cigar:and:pipe</idno><idno type="wicri:Area/Main/Merge">007121</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)</title><author><name sortKey="Bertuccio, P" sort="Bertuccio, P" uniqKey="Bertuccio P" first="P." last="Bertuccio">P. Bertuccio</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Occupational Health, Section of Medical Statistics, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="La Vecchia, C" sort="La Vecchia, C" uniqKey="La Vecchia C" first="C." last="La Vecchia">C. La Vecchia</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Occupational Health, Section of Medical Statistics, University of Milan</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Silverman, D T" sort="Silverman, D T" uniqKey="Silverman D" first="D. T." last="Silverman">D. T. Silverman</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Cancer Institute</s1><s2>Bethesda</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Cancer Institute</wicri:noRegion></affiliation></author><author><name sortKey="Petersen, G M" sort="Petersen, G M" uniqKey="Petersen G" first="G. M." last="Petersen">G. M. Petersen</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Mayo Clinic</s1><s2>Rochester</s2><s3>USA</s3><sZ>4 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Mayo Clinic</wicri:noRegion></affiliation></author><author><name sortKey="Bracci, P M" sort="Bracci, P M" uniqKey="Bracci P" first="P. M." last="Bracci">P. M. Bracci</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>University of California</s1><s2>San Francisco</s2><s3>USA</s3><sZ>5 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Negri, E" sort="Negri, E" uniqKey="Negri E" first="E." last="Negri">E. Negri</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Li, D" sort="Li, D" uniqKey="Li D" first="D." last="Li">D. Li</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>The University of Texas M.D Anderson Cancer Center</s1><s2>Houston</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Risch, H A" sort="Risch, H A" uniqKey="Risch H" first="H. A." last="Risch">H. A. Risch</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Epidemiology and Public Health, Yale University School of Medicine</s1><s2>New Haven</s2><s3>USA</s3><sZ>8 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Haven</wicri:noRegion></affiliation></author><author><name sortKey="Olson, S H" sort="Olson, S H" uniqKey="Olson S" first="S. H." last="Olson">S. H. Olson</name><affiliation wicri:level="2"><inist:fA14 i1="08"><s1>Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center</s1><s2>New York</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Gallinger, S" sort="Gallinger, S" uniqKey="Gallinger S" first="S." last="Gallinger">S. Gallinger</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Toronto General Hospital</s1><s3>CAN</s3><sZ>10 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Toronto General Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Miller, A B" sort="Miller, A B" uniqKey="Miller A" first="A. B." last="Miller">A. B. Miller</name><affiliation wicri:level="4"><inist:fA14 i1="10"><s1>Dalla Lana School of Public Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>11 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Bueno De Mesquita, H B" sort="Bueno De Mesquita, H B" uniqKey="Bueno De Mesquita H" first="H. B." last="Bueno-De-Mesquita">H. B. Bueno-De-Mesquita</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>National Institute for Public Health and the Environment (RIVM)</s1><s2>Bilthoven</s2><s3>NLD</s3><sZ>12 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>National Institute for Public Health and the Environment (RIVM)</wicri:noRegion></affiliation><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU)</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>12 aut.</sZ><sZ>21 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Talamini, R" sort="Talamini, R" uniqKey="Talamini R" first="R." last="Talamini">R. Talamini</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO)</s1><s2>Aviano</s2><s3>ITA</s3><sZ>13 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Polesel, J" sort="Polesel, J" uniqKey="Polesel J" first="J." last="Polesel">J. Polesel</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO)</s1><s2>Aviano</s2><s3>ITA</s3><sZ>13 aut.</sZ><sZ>14 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Ghadirian, P" sort="Ghadirian, P" uniqKey="Ghadirian P" first="P." last="Ghadirian">P. Ghadirian</name><affiliation wicri:level="3"><inist:fA14 i1="14"><s1>Epidemiology Research Unit, Research Centre (CRCHUM)</s1><s2>Montreal</s2><s3>CAN</s3><sZ>15 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Baghurst, P A" sort="Baghurst, P A" uniqKey="Baghurst P" first="P. A." last="Baghurst">P. A. Baghurst</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Public Health, Women's and Children's Hospital</s1><s2>Adelaide</s2><s3>AUS</s3><sZ>16 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author><author><name sortKey="Zatonski, W" sort="Zatonski, W" uniqKey="Zatonski W" first="W." last="Zatonski">W. Zatonski</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Cancer Center & Institute of Oncology</s1><s2>Warsaw</s2><s3>POL</s3><sZ>17 aut.</sZ></inist:fA14><country>Pologne</country><wicri:noRegion>Cancer Center & Institute of Oncology</wicri:noRegion></affiliation></author><author><name sortKey="Fontham, E T" sort="Fontham, E T" uniqKey="Fontham E" first="E. T." last="Fontham">E. T. Fontham</name><affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Louisiana State University, School of Public Health</s1><s2>New Orleans</s2><s3>USA</s3><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Orleans</wicri:noRegion></affiliation></author><author><name sortKey="Bamlet, W R" sort="Bamlet, W R" uniqKey="Bamlet W" first="W. R." last="Bamlet">W. R. Bamlet</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Mayo Clinic</s1><s2>Rochester</s2><s3>USA</s3><sZ>4 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Mayo Clinic</wicri:noRegion></affiliation></author><author><name sortKey="Holly, E A" sort="Holly, E A" uniqKey="Holly E" first="E. A." last="Holly">E. A. Holly</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>University of California</s1><s2>San Francisco</s2><s3>USA</s3><sZ>5 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Lucenteforte, E" sort="Lucenteforte, E" uniqKey="Lucenteforte E" first="E." last="Lucenteforte">E. Lucenteforte</name><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU)</s1><s2>Utrecht</s2><s3>NLD</s3><sZ>12 aut.</sZ><sZ>21 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Hassan, M" sort="Hassan, M" uniqKey="Hassan M" first="M." last="Hassan">M. Hassan</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>The University of Texas M.D Anderson Cancer Center</s1><s2>Houston</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>22 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Yu, H" sort="Yu, H" uniqKey="Yu H" first="H." last="Yu">H. Yu</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Epidemiology and Public Health, Yale University School of Medicine</s1><s2>New Haven</s2><s3>USA</s3><sZ>8 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New Haven</wicri:noRegion></affiliation></author><author><name sortKey="Kurtz, R C" sort="Kurtz, R C" uniqKey="Kurtz R" first="R. C." last="Kurtz">R. C. Kurtz</name><affiliation wicri:level="2"><inist:fA14 i1="18"><s1>Department of Medicine, Memorial Sloan-Kettering Cancer Center</s1><s2>New York</s2><s3>USA</s3><sZ>24 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Cotterchio, M" sort="Cotterchio, M" uniqKey="Cotterchio M" first="M." last="Cotterchio">M. Cotterchio</name><affiliation wicri:level="4"><inist:fA14 i1="10"><s1>Dalla Lana School of Public Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>11 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Cancer Care Ontario</s1><s2>Toronto</s2><s3>CAN</s3><sZ>25 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Cancer Care Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Su, J" sort="Su, J" uniqKey="Su J" first="J." last="Su">J. Su</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>National Cancer Institute</s1><s2>Bethesda</s2><s3>USA</s3><sZ>3 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>National Cancer Institute</wicri:noRegion></affiliation></author><author><name sortKey="Maisonneuve, P" sort="Maisonneuve, P" uniqKey="Maisonneuve P" first="P." last="Maisonneuve">P. Maisonneuve</name><affiliation wicri:level="3"><inist:fA14 i1="20"><s1>European Institute of Oncology</s1><s2>Milan</s2><s3>ITA</s3><sZ>27 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Duell, E J" sort="Duell, E J" uniqKey="Duell E" first="E. J." last="Duell">E. J. Duell</name><affiliation wicri:level="3"><inist:fA14 i1="21"><s1>Catalan Institute of Oncology (ICO)</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>28 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bosetti, C" sort="Bosetti, C" uniqKey="Bosetti C" first="C." last="Bosetti">C. Bosetti</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Department of Epidemiology, Istituto di Ricerche Farmacologiche "Mario Negri</s1><s2>Milan</s2><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>6 aut.</sZ><sZ>29 aut.</sZ></inist:fA14><country>Italie</country><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Boffetta, P" sort="Boffetta, P" uniqKey="Boffetta P" first="P." last="Boffetta">P. Boffetta</name><affiliation wicri:level="3"><inist:fA14 i1="22"><s1>International Prevention Research Institute</s1><s2>Lyon</s2><s3>FRA</s3><sZ>30 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation><affiliation wicri:level="2"><inist:fA14 i1="23"><s1>The Tisch Cancer Institute, Mount Sinai School of Medicine</s1><s2>New York</s2><s3>USA</s3><sZ>30 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Annals of oncology</title><title level="j" type="abbreviated">Ann. oncol.</title><idno type="ISSN">0923-7534</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Annals of oncology</title><title level="j" type="abbreviated">Ann. oncol.</title><idno type="ISSN">0923-7534</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Analysis</term><term>Case control study</term><term>Cigar</term><term>Human</term><term>International</term><term>Pancreas cancer</term><term>Smokeless tobacco</term><term>Tobacco smoking</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Cigare</term><term>Tabagisme</term><term>Tabac sans fumée</term><term>Cancer du pancréas</term><term>Analyse</term><term>International</term><term>Homme</term><term>Etude cas témoin</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Tabagisme</term><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Cigarette smoking is the best-characterized risk factor for pancreatic cancer. However, data are limited for other tobacco smoking products and smokeless tobacco. Materials and methods: We conducted a pooled analysis of cigar and pipe smoking and smokeless tobacco use and risk of pancreatic cancer using data from 11 case-control studies (6056 cases and 11 338 controls) within the International Pancreatic Cancer Case-Control Consortium (PanC4). Pooled odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated by unconditional multiple logistic regression models adjusted for study center and selected covariates. Results: Compared with never tobacco users, the OR for cigar-only smokers was 1.6 (95% CI: 1.2-2.3), i.e. comparable to that of cigarette-only smokers (OR 1.5; 95% CI 1.4-1.6). The OR was 1.1 (95% CI 0.69-1.6) for pipe-only smokers. There was some evidence of increasing risk with increasing amount of cigar smoked per day (OR 1.82 for ≥ 10 grams of tobacco), although not with duration. The OR for ever smokeless tobacco users as compared with never tobacco users was 0.98 (95% CI 0.75-1.3). Conclusion: This collaborative analysis provides evidence that cigar smoking is associated with an excess risk of pancreatic cancer, while no significant association emerged for pipe smoking and smokeless tobacco use.</div></front></TEI></INIST><PMC><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)</title><author><name sortKey="Bertuccio, P" sort="Bertuccio, P" uniqKey="Bertuccio P" first="P." last="Bertuccio">P. Bertuccio</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="La Vecchia, C" sort="La Vecchia, C" uniqKey="La Vecchia C" first="C." last="La Vecchia">C. La Vecchia</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Silverman, D T" sort="Silverman, D T" uniqKey="Silverman D" first="D. T." last="Silverman">D. T. Silverman</name><affiliation><nlm:aff id="aff3">National Cancer Institute, Bethesda</nlm:aff><wicri:noCountry code="subfield">Bethesda</wicri:noCountry></affiliation></author><author><name sortKey="Petersen, G M" sort="Petersen, G M" uniqKey="Petersen G" first="G. M." last="Petersen">G. M. Petersen</name><affiliation><nlm:aff id="aff4">Mayo Clinic, Rochester</nlm:aff><wicri:noCountry code="subfield">Rochester</wicri:noCountry></affiliation></author><author><name sortKey="Bracci, P M" sort="Bracci, P M" uniqKey="Bracci P" first="P. M." last="Bracci">P. M. Bracci</name><affiliation wicri:level="3"><nlm:aff id="aff5">University of California, San Francisco</nlm:aff><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName><wicri:orgArea>University of California</wicri:orgArea></affiliation></author><author><name sortKey="Negri, E" sort="Negri, E" uniqKey="Negri E" first="E." last="Negri">E. Negri</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Li, D" sort="Li, D" uniqKey="Li D" first="D." last="Li">D. Li</name><affiliation wicri:level="3"><nlm:aff id="aff6">The University of Texas M.D Anderson Cancer Center, Houston</nlm:aff><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><wicri:orgArea>The University of Texas M.D Anderson Cancer Center</wicri:orgArea></affiliation></author><author><name sortKey="Risch, H A" sort="Risch, H A" uniqKey="Risch H" first="H. A." last="Risch">H. A. Risch</name><affiliation><nlm:aff id="aff7">Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven</nlm:aff><wicri:noCountry code="subfield">New Haven</wicri:noCountry></affiliation></author><author><name sortKey="Olson, S H" sort="Olson, S H" uniqKey="Olson S" first="S. H." last="Olson">S. H. Olson</name><affiliation wicri:level="2"><nlm:aff id="aff8">Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Gallinger, S" sort="Gallinger, S" uniqKey="Gallinger S" first="S." last="Gallinger">S. Gallinger</name><affiliation><nlm:aff id="aff9">Toronto General Hospital</nlm:aff></affiliation></author><author><name sortKey="Miller, A B" sort="Miller, A B" uniqKey="Miller A" first="A. B." last="Miller">A. B. Miller</name><affiliation wicri:level="4"><nlm:aff id="aff10">Dalla Lana School of Public Health, University of Toronto, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Dalla Lana School of Public Health, University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bueno De Mesquita, H B" sort="Bueno De Mesquita, H B" uniqKey="Bueno De Mesquita H" first="H. B." last="Bueno-De-Mesquita">H. B. Bueno-De-Mesquita</name><affiliation><nlm:aff id="aff11">National Institute for Public Health and the Environment (RIVM), Bilthoven</nlm:aff><wicri:noCountry code="subfield">Bilthoven</wicri:noCountry></affiliation><affiliation wicri:level="3"><nlm:aff id="aff12">Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU), Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Talamini, R" sort="Talamini, R" uniqKey="Talamini R" first="R." last="Talamini">R. Talamini</name><affiliation wicri:level="1"><nlm:aff id="aff13">Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO), Aviano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO), Aviano</wicri:regionArea><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Polesel, J" sort="Polesel, J" uniqKey="Polesel J" first="J." last="Polesel">J. Polesel</name><affiliation wicri:level="1"><nlm:aff id="aff13">Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO), Aviano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO), Aviano</wicri:regionArea><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Ghadirian, P" sort="Ghadirian, P" uniqKey="Ghadirian P" first="P." last="Ghadirian">P. Ghadirian</name><affiliation wicri:level="3"><nlm:aff id="aff14">Epidemiology Research Unit, Research Centre (CRCHUM), Montréal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Epidemiology Research Unit, Research Centre (CRCHUM), Montréal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Baghurst, P A" sort="Baghurst, P A" uniqKey="Baghurst P" first="P. A." last="Baghurst">P. A. Baghurst</name><affiliation wicri:level="1"><nlm:aff id="aff15">Public Health, Women's and Children's Hospital, Adelaide, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Public Health, Women's and Children's Hospital, Adelaide</wicri:regionArea><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author><author><name sortKey="Zatonski, W" sort="Zatonski, W" uniqKey="Zatonski W" first="W." last="Zatonski">W. Zatonski</name><affiliation wicri:level="1"><nlm:aff id="aff16">Cancer Center & Institute of Oncology, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Cancer Center & Institute of Oncology, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Fontham, E T" sort="Fontham, E T" uniqKey="Fontham E" first="E. T." last="Fontham">E. T. Fontham</name><affiliation><nlm:aff id="aff17">Louisiana State University, School of Public Health, New Orleans</nlm:aff><wicri:noCountry code="subfield">New Orleans</wicri:noCountry></affiliation></author><author><name sortKey="Bamlet, W R" sort="Bamlet, W R" uniqKey="Bamlet W" first="W. R." last="Bamlet">W. R. Bamlet</name><affiliation><nlm:aff id="aff4">Mayo Clinic, Rochester</nlm:aff><wicri:noCountry code="subfield">Rochester</wicri:noCountry></affiliation></author><author><name sortKey="Holly, E A" sort="Holly, E A" uniqKey="Holly E" first="E. A." last="Holly">E. A. Holly</name><affiliation wicri:level="3"><nlm:aff id="aff5">University of California, San Francisco</nlm:aff><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName><wicri:orgArea>University of California</wicri:orgArea></affiliation></author><author><name sortKey="Lucenteforte, E" sort="Lucenteforte, E" uniqKey="Lucenteforte E" first="E." last="Lucenteforte">E. Lucenteforte</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Hassan, M" sort="Hassan, M" uniqKey="Hassan M" first="M." last="Hassan">M. Hassan</name><affiliation wicri:level="3"><nlm:aff id="aff6">The University of Texas M.D Anderson Cancer Center, Houston</nlm:aff><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><wicri:orgArea>The University of Texas M.D Anderson Cancer Center</wicri:orgArea></affiliation></author><author><name sortKey="Yu, H" sort="Yu, H" uniqKey="Yu H" first="H." last="Yu">H. Yu</name><affiliation><nlm:aff id="aff7">Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven</nlm:aff><wicri:noCountry code="subfield">New Haven</wicri:noCountry></affiliation></author><author><name sortKey="Kurtz, R C" sort="Kurtz, R C" uniqKey="Kurtz R" first="R. C." last="Kurtz">R. C. Kurtz</name><affiliation wicri:level="2"><nlm:aff id="aff18">Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Cotterchio, M" sort="Cotterchio, M" uniqKey="Cotterchio M" first="M." last="Cotterchio">M. Cotterchio</name><affiliation wicri:level="4"><nlm:aff id="aff10">Dalla Lana School of Public Health, University of Toronto, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Dalla Lana School of Public Health, University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff19">Cancer Care Ontario, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Cancer Care Ontario, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Su, J" sort="Su, J" uniqKey="Su J" first="J." last="Su">J. Su</name><affiliation><nlm:aff id="aff3">National Cancer Institute, Bethesda</nlm:aff><wicri:noCountry code="subfield">Bethesda</wicri:noCountry></affiliation></author><author><name sortKey="Maisonneuve, P" sort="Maisonneuve, P" uniqKey="Maisonneuve P" first="P." last="Maisonneuve">P. Maisonneuve</name><affiliation wicri:level="3"><nlm:aff id="aff20">European Institute of Oncology, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>European Institute of Oncology, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Duell, E J" sort="Duell, E J" uniqKey="Duell E" first="E. J." last="Duell">E. J. Duell</name><affiliation wicri:level="3"><nlm:aff id="aff21">Catalan Institute of Oncology (ICO), Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Catalan Institute of Oncology (ICO), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bosetti, C" sort="Bosetti, C" uniqKey="Bosetti C" first="C." last="Bosetti">C. Bosetti</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Boffetta, P" sort="Boffetta, P" uniqKey="Boffetta P" first="P." last="Boffetta">P. Boffetta</name><affiliation wicri:level="3"><nlm:aff id="aff22">International Prevention Research Institute, Lyon, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>International Prevention Research Institute, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff23">The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Tisch Cancer Institute, Mount Sinai School of Medicine, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21245160</idno><idno type="pmc">3139985</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139985</idno><idno type="RBID">PMC:3139985</idno><idno type="doi">10.1093/annonc/mdq613</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">001732</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001732</idno><idno type="wicri:Area/Pmc/Curation">001592</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001592</idno><idno type="wicri:Area/Pmc/Checkpoint">002379</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002379</idno><idno type="wicri:Area/Ncbi/Merge">000961</idno><idno type="wicri:Area/Ncbi/Curation">000961</idno><idno type="wicri:Area/Ncbi/Checkpoint">000961</idno><idno type="wicri:doubleKey">0923-7534:2011:Bertuccio P:cigar:and:pipe</idno><idno type="wicri:Area/Main/Merge">006574</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)</title><author><name sortKey="Bertuccio, P" sort="Bertuccio, P" uniqKey="Bertuccio P" first="P." last="Bertuccio">P. Bertuccio</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="La Vecchia, C" sort="La Vecchia, C" uniqKey="La Vecchia C" first="C." last="La Vecchia">C. La Vecchia</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Silverman, D T" sort="Silverman, D T" uniqKey="Silverman D" first="D. T." last="Silverman">D. T. Silverman</name><affiliation><nlm:aff id="aff3">National Cancer Institute, Bethesda</nlm:aff><wicri:noCountry code="subfield">Bethesda</wicri:noCountry></affiliation></author><author><name sortKey="Petersen, G M" sort="Petersen, G M" uniqKey="Petersen G" first="G. M." last="Petersen">G. M. Petersen</name><affiliation><nlm:aff id="aff4">Mayo Clinic, Rochester</nlm:aff><wicri:noCountry code="subfield">Rochester</wicri:noCountry></affiliation></author><author><name sortKey="Bracci, P M" sort="Bracci, P M" uniqKey="Bracci P" first="P. M." last="Bracci">P. M. Bracci</name><affiliation wicri:level="3"><nlm:aff id="aff5">University of California, San Francisco</nlm:aff><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName><wicri:orgArea>University of California</wicri:orgArea></affiliation></author><author><name sortKey="Negri, E" sort="Negri, E" uniqKey="Negri E" first="E." last="Negri">E. Negri</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Li, D" sort="Li, D" uniqKey="Li D" first="D." last="Li">D. Li</name><affiliation wicri:level="3"><nlm:aff id="aff6">The University of Texas M.D Anderson Cancer Center, Houston</nlm:aff><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><wicri:orgArea>The University of Texas M.D Anderson Cancer Center</wicri:orgArea></affiliation></author><author><name sortKey="Risch, H A" sort="Risch, H A" uniqKey="Risch H" first="H. A." last="Risch">H. A. Risch</name><affiliation><nlm:aff id="aff7">Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven</nlm:aff><wicri:noCountry code="subfield">New Haven</wicri:noCountry></affiliation></author><author><name sortKey="Olson, S H" sort="Olson, S H" uniqKey="Olson S" first="S. H." last="Olson">S. H. Olson</name><affiliation wicri:level="2"><nlm:aff id="aff8">Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Gallinger, S" sort="Gallinger, S" uniqKey="Gallinger S" first="S." last="Gallinger">S. Gallinger</name><affiliation><nlm:aff id="aff9">Toronto General Hospital</nlm:aff></affiliation></author><author><name sortKey="Miller, A B" sort="Miller, A B" uniqKey="Miller A" first="A. B." last="Miller">A. B. Miller</name><affiliation wicri:level="4"><nlm:aff id="aff10">Dalla Lana School of Public Health, University of Toronto, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Dalla Lana School of Public Health, University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bueno De Mesquita, H B" sort="Bueno De Mesquita, H B" uniqKey="Bueno De Mesquita H" first="H. B." last="Bueno-De-Mesquita">H. B. Bueno-De-Mesquita</name><affiliation><nlm:aff id="aff11">National Institute for Public Health and the Environment (RIVM), Bilthoven</nlm:aff><wicri:noCountry code="subfield">Bilthoven</wicri:noCountry></affiliation><affiliation wicri:level="3"><nlm:aff id="aff12">Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU), Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gastroenterology and Hepatology, University Medical Center Utrecht (UMCU), Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Talamini, R" sort="Talamini, R" uniqKey="Talamini R" first="R." last="Talamini">R. Talamini</name><affiliation wicri:level="1"><nlm:aff id="aff13">Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO), Aviano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO), Aviano</wicri:regionArea><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Polesel, J" sort="Polesel, J" uniqKey="Polesel J" first="J." last="Polesel">J. Polesel</name><affiliation wicri:level="1"><nlm:aff id="aff13">Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO), Aviano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Epidemiology and Biostatistics, Centro di Riferimento Oncologico (CRO), Aviano</wicri:regionArea><wicri:noRegion>Aviano</wicri:noRegion></affiliation></author><author><name sortKey="Ghadirian, P" sort="Ghadirian, P" uniqKey="Ghadirian P" first="P." last="Ghadirian">P. Ghadirian</name><affiliation wicri:level="3"><nlm:aff id="aff14">Epidemiology Research Unit, Research Centre (CRCHUM), Montréal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Epidemiology Research Unit, Research Centre (CRCHUM), Montréal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName></affiliation></author><author><name sortKey="Baghurst, P A" sort="Baghurst, P A" uniqKey="Baghurst P" first="P. A." last="Baghurst">P. A. Baghurst</name><affiliation wicri:level="1"><nlm:aff id="aff15">Public Health, Women's and Children's Hospital, Adelaide, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Public Health, Women's and Children's Hospital, Adelaide</wicri:regionArea><wicri:noRegion>Adelaide</wicri:noRegion></affiliation></author><author><name sortKey="Zatonski, W" sort="Zatonski, W" uniqKey="Zatonski W" first="W." last="Zatonski">W. Zatonski</name><affiliation wicri:level="1"><nlm:aff id="aff16">Cancer Center & Institute of Oncology, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Cancer Center & Institute of Oncology, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Fontham, E T" sort="Fontham, E T" uniqKey="Fontham E" first="E. T." last="Fontham">E. T. Fontham</name><affiliation><nlm:aff id="aff17">Louisiana State University, School of Public Health, New Orleans</nlm:aff><wicri:noCountry code="subfield">New Orleans</wicri:noCountry></affiliation></author><author><name sortKey="Bamlet, W R" sort="Bamlet, W R" uniqKey="Bamlet W" first="W. R." last="Bamlet">W. R. Bamlet</name><affiliation><nlm:aff id="aff4">Mayo Clinic, Rochester</nlm:aff><wicri:noCountry code="subfield">Rochester</wicri:noCountry></affiliation></author><author><name sortKey="Holly, E A" sort="Holly, E A" uniqKey="Holly E" first="E. A." last="Holly">E. A. Holly</name><affiliation wicri:level="3"><nlm:aff id="aff5">University of California, San Francisco</nlm:aff><country>États-Unis</country><placeName><settlement type="city">San Francisco</settlement><region type="state">Californie</region></placeName><wicri:orgArea>University of California</wicri:orgArea></affiliation></author><author><name sortKey="Lucenteforte, E" sort="Lucenteforte, E" uniqKey="Lucenteforte E" first="E." last="Lucenteforte">E. Lucenteforte</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Occupational Health, Section of Medical Statistics, University of Milan, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Hassan, M" sort="Hassan, M" uniqKey="Hassan M" first="M." last="Hassan">M. Hassan</name><affiliation wicri:level="3"><nlm:aff id="aff6">The University of Texas M.D Anderson Cancer Center, Houston</nlm:aff><country>États-Unis</country><placeName><settlement type="city">Houston</settlement><region type="state">Texas</region></placeName><wicri:orgArea>The University of Texas M.D Anderson Cancer Center</wicri:orgArea></affiliation></author><author><name sortKey="Yu, H" sort="Yu, H" uniqKey="Yu H" first="H." last="Yu">H. Yu</name><affiliation><nlm:aff id="aff7">Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven</nlm:aff><wicri:noCountry code="subfield">New Haven</wicri:noCountry></affiliation></author><author><name sortKey="Kurtz, R C" sort="Kurtz, R C" uniqKey="Kurtz R" first="R. C." last="Kurtz">R. C. Kurtz</name><affiliation wicri:level="2"><nlm:aff id="aff18">Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Cotterchio, M" sort="Cotterchio, M" uniqKey="Cotterchio M" first="M." last="Cotterchio">M. Cotterchio</name><affiliation wicri:level="4"><nlm:aff id="aff10">Dalla Lana School of Public Health, University of Toronto, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Dalla Lana School of Public Health, University of Toronto, Toronto</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff19">Cancer Care Ontario, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Cancer Care Ontario, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Su, J" sort="Su, J" uniqKey="Su J" first="J." last="Su">J. Su</name><affiliation><nlm:aff id="aff3">National Cancer Institute, Bethesda</nlm:aff><wicri:noCountry code="subfield">Bethesda</wicri:noCountry></affiliation></author><author><name sortKey="Maisonneuve, P" sort="Maisonneuve, P" uniqKey="Maisonneuve P" first="P." last="Maisonneuve">P. Maisonneuve</name><affiliation wicri:level="3"><nlm:aff id="aff20">European Institute of Oncology, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>European Institute of Oncology, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Duell, E J" sort="Duell, E J" uniqKey="Duell E" first="E. J." last="Duell">E. J. Duell</name><affiliation wicri:level="3"><nlm:aff id="aff21">Catalan Institute of Oncology (ICO), Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Catalan Institute of Oncology (ICO), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bosetti, C" sort="Bosetti, C" uniqKey="Bosetti C" first="C." last="Bosetti">C. Bosetti</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Epidemiology, Istituto di Ricerche Farmacologiche “Mario Negri”, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Boffetta, P" sort="Boffetta, P" uniqKey="Boffetta P" first="P." last="Boffetta">P. Boffetta</name><affiliation wicri:level="3"><nlm:aff id="aff22">International Prevention Research Institute, Lyon, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>International Prevention Research Institute, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff23">The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Tisch Cancer Institute, Mount Sinai School of Medicine, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author></analytic><series><title level="j">Annals of Oncology</title><idno type="ISSN">0923-7534</idno><idno type="eISSN">1569-8041</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><bold>Background:</bold> Cigarette smoking is the best-characterized risk factor for pancreatic cancer. However, data are limited for other tobacco smoking products and smokeless tobacco.</p><p><bold>Materials and methods:</bold> We conducted a pooled analysis of cigar and pipe smoking and smokeless tobacco use and risk of pancreatic cancer using data from 11 case–control studies (6056 cases and 11 338 controls) within the International Pancreatic Cancer Case-Control Consortium (PanC4). Pooled odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated by unconditional multiple logistic regression models adjusted for study center and selected covariates.</p><p><bold>Results:</bold> Compared with never tobacco users, the OR for cigar-only smokers was 1.6 (95% CI: 1.2–2.3), i.e. comparable to that of cigarette-only smokers (OR 1.5; 95% CI 1.4–1.6). The OR was 1.1 (95% CI 0.69–1.6) for pipe-only smokers. There was some evidence of increasing risk with increasing amount of cigar smoked per day (OR 1.82 for ≥ 10 grams of tobacco), although not with duration. The OR for ever smokeless tobacco users as compared with never tobacco users was 0.98 (95% CI 0.75–1.3).</p><p><bold>Conclusion:</bold> This collaborative analysis provides evidence that cigar smoking is associated with an excess risk of pancreatic cancer, while no significant association emerged for pipe smoking and smokeless tobacco use.</p></div></front></TEI></PMC></double></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006C62 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 006C62 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Curation
|type= RBID
|clé= Pascal:11-0317098
|texte= Cigar and pipe smoking, smokeless tobacco use and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (PanC4)
}}
| This area was generated with Dilib version V0.6.33. |  |