The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys
Identifieur interne : 000240 ( Main/Curation ); précédent : 000239; suivant : 000241The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys
Auteurs : Fernando Navarro-Mateu [Espagne] ; Jordi Alonso [Espagne] ; Carmen C. W. Lim [Australie] ; Sukanta Saha [Australie] ; Sergio Aguilar-Gaxiola [États-Unis] ; Ali Al-Hamzawi [Iraq] ; Laura H. Andrade [Brésil] ; Evelyn J. Bromet [États-Unis] ; Ronny Bruffaerts [Belgique] ; Somnath Chatterji [Suisse] ; Louisa Degenhardt [Australie] ; Giovanni De Girolamo [Italie] ; Peter De Jonge ; John Fayyad [Liban] ; Silvia Florescu [Roumanie] ; Oye Gureje [Nigeria] ; Josep M. Haro [Espagne] ; Chiyi Hu [République populaire de Chine] ; Elie G. Karam [Liban] ; Viviane Kovess-Masfety [France] ; Sing Lee [Hong Kong] ; Maria E. Medina-Mora [Mexique] ; Akin Ojagbemi [Nigeria] ; Beth-Ellen Pennell [États-Unis] ; Jose Posada-Villa [Colombie] ; Kate M. Scott [Nouvelle-Zélande] ; Juan Carlos Stagnaro [Argentine] ; Kenneth S. Kendler [États-Unis] ; Ronald C. Kessler [États-Unis] ; John J. Mcgrath [Danemark]Source :
- Acta psychiatrica Scandinavica [ 0001-690X ] ; 2017.
Abstract
While psychotic experiences (PEs) are known to be associated with a range of mental and general medical disorders, little is known about the association between PEs and measures of disability. We aimed to investigate this question using the World Mental Health surveys.
Lifetime occurrences of 6 types of PEs were assessed along with 21 mental disorders and 14 general medical conditions. Disability was assessed with a modified version of the WHO Disability Assessment Schedule. Descriptive statistics and logistic regression models were used to investigate the association between PEs and high disability scores (top quartile) with various adjustments.
Respondents with PEs were more likely to have top quartile scores on global disability than respondents without PEs (19.1% vs. 7.5%; χ2 = 190.1, p<.001) as well as greater likelihood of cognitive, social, and role impairment. Relationships persisted in each adjusted model. A significant dose-response relationship was also found for the PE type measures with most of these outcomes.
Psychotic experiences are associated with disability measures with a dose response relationship. These results are consistent with the view that PEs are associated with disability regardless of the presence of comorbid mental or general medical disorders.
Url:
DOI: 10.1111/acps.12749
PubMed: 28542726
PubMed Central: 5664954
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Peter De Jonge<affiliation><nlm:aff id="A13">Developmental Psychology, Department of Psychology, Rijksuniversiteit Groningen, Groningen, NL; Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University Medical</nlm:aff>
<wicri:noCountry code="subfield">University Medical</wicri:noCountry>
</affiliation>
Le document en format XML
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<author><name sortKey="Scott, Kate M" sort="Scott, Kate M" uniqKey="Scott K" first="Kate M." last="Scott">Kate M. Scott</name>
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<author><name sortKey="Stagnaro, Juan Carlos" sort="Stagnaro, Juan Carlos" uniqKey="Stagnaro J" first="Juan Carlos" last="Stagnaro">Juan Carlos Stagnaro</name>
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<affiliation wicri:level="1"><nlm:aff id="A1">UDIF-SM, Subdirección General de Planificación, Innovación y Cronicidad, Servicio Murciano de Salud. IMIB-Arrixaca. CIBERESP-Murcia, Murcia, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>UDIF-SM, Subdirección General de Planificación, Innovación y Cronicidad, Servicio Murciano de Salud. IMIB-Arrixaca. CIBERESP-Murcia, Murcia</wicri:regionArea>
<wicri:noRegion>Murcia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Alonso, Jordi" sort="Alonso, Jordi" uniqKey="Alonso J" first="Jordi" last="Alonso">Jordi Alonso</name>
<affiliation wicri:level="3"><nlm:aff id="A2">Health Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain; Pompeu Fabra University (UPF), Barcelona, Spain; and CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Health Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain; Pompeu Fabra University (UPF), Barcelona, Spain; and CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lim, Carmen C W" sort="Lim, Carmen C W" uniqKey="Lim C" first="Carmen C. W." last="Lim">Carmen C. W. Lim</name>
<affiliation wicri:level="1"><nlm:aff id="A3">Queensland Brain Institute, The University of Queensland, St. Lucia, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Queensland Brain Institute, The University of Queensland, St. Lucia, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Saha, Sukanta" sort="Saha, Sukanta" uniqKey="Saha S" first="Sukanta" last="Saha">Sukanta Saha</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Queensland Centre for Mental Health Research, and Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Queensland Centre for Mental Health Research, and Queensland Brain Institute, University of Queensland, St. Lucia, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Aguilar Gaxiola, Sergio" sort="Aguilar Gaxiola, Sergio" uniqKey="Aguilar Gaxiola S" first="Sergio" last="Aguilar-Gaxiola">Sergio Aguilar-Gaxiola</name>
<affiliation wicri:level="2"><nlm:aff id="A5">Center for Reducing Health Disparities, UC Davis Health System, Sacramento, California, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Reducing Health Disparities, UC Davis Health System, Sacramento, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Al Hamzawi, Ali" sort="Al Hamzawi, Ali" uniqKey="Al Hamzawi A" first="Ali" last="Al-Hamzawi">Ali Al-Hamzawi</name>
<affiliation wicri:level="1"><nlm:aff id="A6">College of Medicine, Al-Qadisiya University, Diwaniya governorate, Iraq</nlm:aff>
<country xml:lang="fr">Iraq</country>
<wicri:regionArea>College of Medicine, Al-Qadisiya University, Diwaniya governorate</wicri:regionArea>
<wicri:noRegion>Diwaniya governorate</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Andrade, Laura H" sort="Andrade, Laura H" uniqKey="Andrade L" first="Laura H." last="Andrade">Laura H. Andrade</name>
<affiliation wicri:level="3"><nlm:aff id="A7">Section of Psychiatric Epidemiology - LIM 23, Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Section of Psychiatric Epidemiology - LIM 23, Institute of Psychiatry, University of São Paulo Medical School, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bromet, Evelyn J" sort="Bromet, Evelyn J" uniqKey="Bromet E" first="Evelyn J." last="Bromet">Evelyn J. Bromet</name>
<affiliation wicri:level="2"><nlm:aff id="A8">Department of Psychiatry, Stony Brook University School of Medicine, Stony Brook, New York, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, Stony Brook University School of Medicine, Stony Brook, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bruffaerts, Ronny" sort="Bruffaerts, Ronny" uniqKey="Bruffaerts R" first="Ronny" last="Bruffaerts">Ronny Bruffaerts</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Universitair Psychiatrisch Centrum - Katholieke Universiteit Leuven (UPC-KUL), Campus Gasthuisberg, Leuven, Belgium</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Universitair Psychiatrisch Centrum - Katholieke Universiteit Leuven (UPC-KUL), Campus Gasthuisberg, Leuven</wicri:regionArea>
<wicri:noRegion>Leuven</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chatterji, Somnath" sort="Chatterji, Somnath" uniqKey="Chatterji S" first="Somnath" last="Chatterji">Somnath Chatterji</name>
<affiliation wicri:level="1"><nlm:aff id="A10">Department of Information, Evidence and Research, World Health Organization, Geneva, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Information, Evidence and Research, World Health Organization, Geneva</wicri:regionArea>
<wicri:noRegion>Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Degenhardt, Louisa" sort="Degenhardt, Louisa" uniqKey="Degenhardt L" first="Louisa" last="Degenhardt">Louisa Degenhardt</name>
<affiliation wicri:level="1"><nlm:aff id="A11">National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052</wicri:regionArea>
<wicri:noRegion>NSW 2052</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Girolamo, Giovanni" sort="De Girolamo, Giovanni" uniqKey="De Girolamo G" first="Giovanni" last="De Girolamo">Giovanni De Girolamo</name>
<affiliation wicri:level="1"><nlm:aff id="A12">Unit of Epidemiological and Evaluation Psychiatry, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS)-St. John of God Clinical Research Centre, Via Pilastroni 4, Brescia, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Unit of Epidemiological and Evaluation Psychiatry, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS)-St. John of God Clinical Research Centre, Via Pilastroni 4, Brescia</wicri:regionArea>
<wicri:noRegion>Brescia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Jonge, Peter" sort="De Jonge, Peter" uniqKey="De Jonge P" first="Peter" last="De Jonge">Peter De Jonge</name>
<affiliation><nlm:aff id="A13">Developmental Psychology, Department of Psychology, Rijksuniversiteit Groningen, Groningen, NL; Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University Medical</nlm:aff>
<wicri:noCountry code="subfield">University Medical</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fayyad, John" sort="Fayyad, John" uniqKey="Fayyad J" first="John" last="Fayyad">John Fayyad</name>
<affiliation wicri:level="1"><nlm:aff id="A14">Institute for Development, Research, Advocacy & Applied Care (IDRAAC), Beirut, Lebanon</nlm:aff>
<country xml:lang="fr">Liban</country>
<wicri:regionArea>Institute for Development, Research, Advocacy & Applied Care (IDRAAC), Beirut</wicri:regionArea>
<wicri:noRegion>Beirut</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Florescu, Silvia" sort="Florescu, Silvia" uniqKey="Florescu S" first="Silvia" last="Florescu">Silvia Florescu</name>
<affiliation wicri:level="1"><nlm:aff id="A15">National School of Public Health, Management and Professional Development, Bucharest, Romania</nlm:aff>
<country xml:lang="fr">Roumanie</country>
<wicri:regionArea>National School of Public Health, Management and Professional Development, Bucharest</wicri:regionArea>
<wicri:noRegion>Bucharest</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gureje, Oye" sort="Gureje, Oye" uniqKey="Gureje O" first="Oye" last="Gureje">Oye Gureje</name>
<affiliation wicri:level="1"><nlm:aff id="A16">Department of Psychiatry, University College Hospital, Ibadan, Nigeria</nlm:aff>
<country xml:lang="fr">Nigeria</country>
<wicri:regionArea>Department of Psychiatry, University College Hospital, Ibadan</wicri:regionArea>
<wicri:noRegion>Ibadan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Haro, Josep M" sort="Haro, Josep M" uniqKey="Haro J" first="Josep M." last="Haro">Josep M. Haro</name>
<affiliation wicri:level="4"><nlm:aff id="A17">Parc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Parc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
<settlement type="city">Barcelone</settlement>
</placeName>
<orgName type="university">Université de Barcelone</orgName>
</affiliation>
</author>
<author><name sortKey="Hu, Chiyi" sort="Hu, Chiyi" uniqKey="Hu C" first="Chiyi" last="Hu">Chiyi Hu</name>
<affiliation wicri:level="3"><nlm:aff id="A18">Shenzhen Institute of Mental Health & Shenzhen Kangning Hospital, Shenzhen, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Shenzhen Institute of Mental Health & Shenzhen Kangning Hospital, Shenzhen</wicri:regionArea>
<placeName><settlement type="city">Shenzhen</settlement>
<region type="province">Guangdong</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Karam, Elie G" sort="Karam, Elie G" uniqKey="Karam E" first="Elie G." last="Karam">Elie G. Karam</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Psychiatry and Clinical Psychology, Faculty of Medicine, Balamand University, Beirut, Lebanon; Department of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Beirut, Lebanon; Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut, Lebanon</nlm:aff>
<country xml:lang="fr">Liban</country>
<wicri:regionArea>Department of Psychiatry and Clinical Psychology, Faculty of Medicine, Balamand University, Beirut, Lebanon; Department of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Beirut, Lebanon; Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut</wicri:regionArea>
<wicri:noRegion>Beirut</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kovess Masfety, Viviane" sort="Kovess Masfety, Viviane" uniqKey="Kovess Masfety V" first="Viviane" last="Kovess-Masfety">Viviane Kovess-Masfety</name>
<affiliation wicri:level="3"><nlm:aff id="A20">Ecole des Hautes Etudes en Santé Publique (EHESP), EA 4057 Paris Descartes University,Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Ecole des Hautes Etudes en Santé Publique (EHESP), EA 4057 Paris Descartes University,Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lee, Sing" sort="Lee, Sing" uniqKey="Lee S" first="Sing" last="Lee">Sing Lee</name>
<affiliation wicri:level="4"><nlm:aff id="A21">Department of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong</nlm:aff>
<country xml:lang="fr">Hong Kong</country>
<wicri:regionArea>Department of Psychiatry, Chinese University of Hong Kong, Tai Po</wicri:regionArea>
<orgName type="university">Université chinoise de Hong Kong</orgName>
<placeName><settlement type="city">Sha Tin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Medina Mora, Maria E" sort="Medina Mora, Maria E" uniqKey="Medina Mora M" first="Maria E." last="Medina-Mora">Maria E. Medina-Mora</name>
<affiliation wicri:level="1"><nlm:aff id="A22">National Institute of Psychiatry Ramón de la Fuente, Mexico City, Mexico</nlm:aff>
<country xml:lang="fr">Mexique</country>
<wicri:regionArea>National Institute of Psychiatry Ramón de la Fuente, Mexico City</wicri:regionArea>
<wicri:noRegion>Mexico City</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ojagbemi, Akin" sort="Ojagbemi, Akin" uniqKey="Ojagbemi A" first="Akin" last="Ojagbemi">Akin Ojagbemi</name>
<affiliation wicri:level="1"><nlm:aff id="A23">College of Medicine, University of Ibadan; University College Hospital, Ibadan, Nigeria</nlm:aff>
<country xml:lang="fr">Nigeria</country>
<wicri:regionArea>College of Medicine, University of Ibadan; University College Hospital, Ibadan</wicri:regionArea>
<wicri:noRegion>Ibadan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pennell, Beth Ellen" sort="Pennell, Beth Ellen" uniqKey="Pennell B" first="Beth-Ellen" last="Pennell">Beth-Ellen Pennell</name>
<affiliation wicri:level="2"><nlm:aff id="A24">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Posada Villa, Jose" sort="Posada Villa, Jose" uniqKey="Posada Villa J" first="Jose" last="Posada-Villa">Jose Posada-Villa</name>
<affiliation wicri:level="1"><nlm:aff id="A25">Colegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota, Colombia</nlm:aff>
<country xml:lang="fr">Colombie</country>
<wicri:regionArea>Colegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota</wicri:regionArea>
<wicri:noRegion>Bogota</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Scott, Kate M" sort="Scott, Kate M" uniqKey="Scott K" first="Kate M." last="Scott">Kate M. Scott</name>
<affiliation wicri:level="1"><nlm:aff id="A26">Department of Psychological Medicine, University of Otago, Dunedin, Otago, New Zealand</nlm:aff>
<country xml:lang="fr">Nouvelle-Zélande</country>
<wicri:regionArea>Department of Psychological Medicine, University of Otago, Dunedin, Otago</wicri:regionArea>
<wicri:noRegion>Otago</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stagnaro, Juan Carlos" sort="Stagnaro, Juan Carlos" uniqKey="Stagnaro J" first="Juan Carlos" last="Stagnaro">Juan Carlos Stagnaro</name>
<affiliation wicri:level="1"><nlm:aff id="A27">Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Argentina</nlm:aff>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires</wicri:regionArea>
<wicri:noRegion>Universidad de Buenos Aires</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kendler, Kenneth S" sort="Kendler, Kenneth S" uniqKey="Kendler K" first="Kenneth S." last="Kendler">Kenneth S. Kendler</name>
<affiliation wicri:level="1"><nlm:aff id="A28">Department of Psychiatry Virginia Commonwealth University, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry Virginia Commonwealth University</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kessler, Ronald C" sort="Kessler, Ronald C" uniqKey="Kessler R" first="Ronald C." last="Kessler">Ronald C. Kessler</name>
<affiliation wicri:level="2"><nlm:aff id="A29">Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcgrath, John J" sort="Mcgrath, John J" uniqKey="Mcgrath J" first="John J." last="Mcgrath">John J. Mcgrath</name>
<affiliation wicri:level="1"><nlm:aff id="A30">Queensland Centre for Mental Health Research, and Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia; and National Centre for Register-based Research, Aarhus BSS, Aarhus University, Aarhus, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Queensland Centre for Mental Health Research, and Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia; and National Centre for Register-based Research, Aarhus BSS, Aarhus University, Aarhus</wicri:regionArea>
<wicri:noRegion>Aarhus</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Acta psychiatrica Scandinavica</title>
<idno type="ISSN">0001-690X</idno>
<idno type="eISSN">1600-0447</idno>
<imprint><date when="2017">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title>
<p id="P1">While psychotic experiences (PEs) are known to be associated with a range of mental and general medical disorders, little is known about the association between PEs and measures of disability. We aimed to investigate this question using the World Mental Health surveys.</p>
</sec>
<sec id="S2"><title>Method</title>
<p id="P2">Lifetime occurrences of 6 types of PEs were assessed along with 21 mental disorders and 14 general medical conditions. Disability was assessed with a modified version of the WHO Disability Assessment Schedule. Descriptive statistics and logistic regression models were used to investigate the association between PEs and high disability scores (top quartile) with various adjustments.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Respondents with PEs were more likely to have top quartile scores on global disability than respondents without PEs (19.1% vs. 7.5%; χ<sup>2</sup>
= 190.1, p<.001) as well as greater likelihood of cognitive, social, and role impairment. Relationships persisted in each adjusted model. A significant dose-response relationship was also found for the PE type measures with most of these outcomes.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">Psychotic experiences are associated with disability measures with a dose response relationship. These results are consistent with the view that PEs are associated with disability regardless of the presence of comorbid mental or general medical disorders.</p>
</sec>
</div>
</front>
</TEI>
</record>
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