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The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys

Identifieur interne : 001C87 ( Pmc/Corpus ); précédent : 001C86; suivant : 001C88

The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys

Auteurs : Fernando Navarro-Mateu ; Jordi Alonso ; Carmen C. W. Lim ; Sukanta Saha ; Sergio Aguilar-Gaxiola ; Ali Al-Hamzawi ; Laura H. Andrade ; Evelyn J. Bromet ; Ronny Bruffaerts ; Somnath Chatterji ; Louisa Degenhardt ; Giovanni De Girolamo ; Peter De Jonge ; John Fayyad ; Silvia Florescu ; Oye Gureje ; Josep M. Haro ; Chiyi Hu ; Elie G. Karam ; Viviane Kovess-Masfety ; Sing Lee ; Maria E. Medina-Mora ; Akin Ojagbemi ; Beth-Ellen Pennell ; Jose Posada-Villa ; Kate M. Scott ; Juan Carlos Stagnaro ; Kenneth S. Kendler ; Ronald C. Kessler ; John J. Mcgrath

Source :

RBID : PMC:5664954

Abstract

Objective

While psychotic experiences (PEs) are known to be associated with a range of mental and general medical disorders, little is known about the association between PEs and measures of disability. We aimed to investigate this question using the World Mental Health surveys.

Method

Lifetime occurrences of 6 types of PEs were assessed along with 21 mental disorders and 14 general medical conditions. Disability was assessed with a modified version of the WHO Disability Assessment Schedule. Descriptive statistics and logistic regression models were used to investigate the association between PEs and high disability scores (top quartile) with various adjustments.

Results

Respondents with PEs were more likely to have top quartile scores on global disability than respondents without PEs (19.1% vs. 7.5%; χ2 = 190.1, p<.001) as well as greater likelihood of cognitive, social, and role impairment. Relationships persisted in each adjusted model. A significant dose-response relationship was also found for the PE type measures with most of these outcomes.

Conclusions

Psychotic experiences are associated with disability measures with a dose response relationship. These results are consistent with the view that PEs are associated with disability regardless of the presence of comorbid mental or general medical disorders.


Url:
DOI: 10.1111/acps.12749
PubMed: 28542726
PubMed Central: 5664954

Links to Exploration step

PMC:5664954

Le document en format XML

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<nlm:aff id="A1">UDIF-SM, Subdirección General de Planificación, Innovación y Cronicidad, Servicio Murciano de Salud. IMIB-Arrixaca. CIBERESP-Murcia, Murcia, Spain</nlm:aff>
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<name sortKey="Aguilar Gaxiola, Sergio" sort="Aguilar Gaxiola, Sergio" uniqKey="Aguilar Gaxiola S" first="Sergio" last="Aguilar-Gaxiola">Sergio Aguilar-Gaxiola</name>
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<name sortKey="Bromet, Evelyn J" sort="Bromet, Evelyn J" uniqKey="Bromet E" first="Evelyn J." last="Bromet">Evelyn J. Bromet</name>
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<name sortKey="Bruffaerts, Ronny" sort="Bruffaerts, Ronny" uniqKey="Bruffaerts R" first="Ronny" last="Bruffaerts">Ronny Bruffaerts</name>
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<name sortKey="Chatterji, Somnath" sort="Chatterji, Somnath" uniqKey="Chatterji S" first="Somnath" last="Chatterji">Somnath Chatterji</name>
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<name sortKey="Degenhardt, Louisa" sort="Degenhardt, Louisa" uniqKey="Degenhardt L" first="Louisa" last="Degenhardt">Louisa Degenhardt</name>
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<name sortKey="De Girolamo, Giovanni" sort="De Girolamo, Giovanni" uniqKey="De Girolamo G" first="Giovanni" last="De Girolamo">Giovanni De Girolamo</name>
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<nlm:aff id="A12">Unit of Epidemiological and Evaluation Psychiatry, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS)-St. John of God Clinical Research Centre, Via Pilastroni 4, Brescia, Italy</nlm:aff>
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<name sortKey="De Jonge, Peter" sort="De Jonge, Peter" uniqKey="De Jonge P" first="Peter" last="De Jonge">Peter De Jonge</name>
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<name sortKey="Fayyad, John" sort="Fayyad, John" uniqKey="Fayyad J" first="John" last="Fayyad">John Fayyad</name>
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<name sortKey="Florescu, Silvia" sort="Florescu, Silvia" uniqKey="Florescu S" first="Silvia" last="Florescu">Silvia Florescu</name>
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<nlm:aff id="A15">National School of Public Health, Management and Professional Development, Bucharest, Romania</nlm:aff>
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<name sortKey="Gureje, Oye" sort="Gureje, Oye" uniqKey="Gureje O" first="Oye" last="Gureje">Oye Gureje</name>
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<nlm:aff id="A16">Department of Psychiatry, University College Hospital, Ibadan, Nigeria</nlm:aff>
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<name sortKey="Haro, Josep M" sort="Haro, Josep M" uniqKey="Haro J" first="Josep M." last="Haro">Josep M. Haro</name>
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<nlm:aff id="A17">Parc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain</nlm:aff>
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<name sortKey="Hu, Chiyi" sort="Hu, Chiyi" uniqKey="Hu C" first="Chiyi" last="Hu">Chiyi Hu</name>
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<nlm:aff id="A18">Shenzhen Institute of Mental Health & Shenzhen Kangning Hospital, Shenzhen, China</nlm:aff>
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<name sortKey="Karam, Elie G" sort="Karam, Elie G" uniqKey="Karam E" first="Elie G." last="Karam">Elie G. Karam</name>
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<nlm:aff id="A19">Department of Psychiatry and Clinical Psychology, Faculty of Medicine, Balamand University, Beirut, Lebanon; Department of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Beirut, Lebanon; Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut, Lebanon</nlm:aff>
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<name sortKey="Kovess Masfety, Viviane" sort="Kovess Masfety, Viviane" uniqKey="Kovess Masfety V" first="Viviane" last="Kovess-Masfety">Viviane Kovess-Masfety</name>
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<nlm:aff id="A20">Ecole des Hautes Etudes en Santé Publique (EHESP), EA 4057 Paris Descartes University,Paris, France</nlm:aff>
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<name sortKey="Lee, Sing" sort="Lee, Sing" uniqKey="Lee S" first="Sing" last="Lee">Sing Lee</name>
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<nlm:aff id="A21">Department of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong</nlm:aff>
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<name sortKey="Medina Mora, Maria E" sort="Medina Mora, Maria E" uniqKey="Medina Mora M" first="Maria E." last="Medina-Mora">Maria E. Medina-Mora</name>
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<nlm:aff id="A22">National Institute of Psychiatry Ramón de la Fuente, Mexico City, Mexico</nlm:aff>
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<name sortKey="Ojagbemi, Akin" sort="Ojagbemi, Akin" uniqKey="Ojagbemi A" first="Akin" last="Ojagbemi">Akin Ojagbemi</name>
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<nlm:aff id="A23">College of Medicine, University of Ibadan; University College Hospital, Ibadan, Nigeria</nlm:aff>
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<name sortKey="Pennell, Beth Ellen" sort="Pennell, Beth Ellen" uniqKey="Pennell B" first="Beth-Ellen" last="Pennell">Beth-Ellen Pennell</name>
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<nlm:aff id="A24">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
</affiliation>
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<name sortKey="Posada Villa, Jose" sort="Posada Villa, Jose" uniqKey="Posada Villa J" first="Jose" last="Posada-Villa">Jose Posada-Villa</name>
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<nlm:aff id="A25">Colegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota, Colombia</nlm:aff>
</affiliation>
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<name sortKey="Scott, Kate M" sort="Scott, Kate M" uniqKey="Scott K" first="Kate M." last="Scott">Kate M. Scott</name>
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<nlm:aff id="A26">Department of Psychological Medicine, University of Otago, Dunedin, Otago, New Zealand</nlm:aff>
</affiliation>
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<name sortKey="Stagnaro, Juan Carlos" sort="Stagnaro, Juan Carlos" uniqKey="Stagnaro J" first="Juan Carlos" last="Stagnaro">Juan Carlos Stagnaro</name>
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<nlm:aff id="A27">Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Argentina</nlm:aff>
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<name sortKey="Kendler, Kenneth S" sort="Kendler, Kenneth S" uniqKey="Kendler K" first="Kenneth S." last="Kendler">Kenneth S. Kendler</name>
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<nlm:aff id="A28">Department of Psychiatry Virginia Commonwealth University, USA</nlm:aff>
</affiliation>
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<name sortKey="Kessler, Ronald C" sort="Kessler, Ronald C" uniqKey="Kessler R" first="Ronald C." last="Kessler">Ronald C. Kessler</name>
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<nlm:aff id="A29">Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
</affiliation>
</author>
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<name sortKey="Mcgrath, John J" sort="Mcgrath, John J" uniqKey="Mcgrath J" first="John J." last="Mcgrath">John J. Mcgrath</name>
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<nlm:aff id="A30">Queensland Centre for Mental Health Research, and Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia; and National Centre for Register-based Research, Aarhus BSS, Aarhus University, Aarhus, Denmark</nlm:aff>
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<title xml:lang="en" level="a" type="main">The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys</title>
<author>
<name sortKey="Navarro Mateu, Fernando" sort="Navarro Mateu, Fernando" uniqKey="Navarro Mateu F" first="Fernando" last="Navarro-Mateu">Fernando Navarro-Mateu</name>
<affiliation>
<nlm:aff id="A1">UDIF-SM, Subdirección General de Planificación, Innovación y Cronicidad, Servicio Murciano de Salud. IMIB-Arrixaca. CIBERESP-Murcia, Murcia, Spain</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Alonso, Jordi" sort="Alonso, Jordi" uniqKey="Alonso J" first="Jordi" last="Alonso">Jordi Alonso</name>
<affiliation>
<nlm:aff id="A2">Health Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain; Pompeu Fabra University (UPF), Barcelona, Spain; and CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lim, Carmen C W" sort="Lim, Carmen C W" uniqKey="Lim C" first="Carmen C. W." last="Lim">Carmen C. W. Lim</name>
<affiliation>
<nlm:aff id="A3">Queensland Brain Institute, The University of Queensland, St. Lucia, Queensland, Australia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Saha, Sukanta" sort="Saha, Sukanta" uniqKey="Saha S" first="Sukanta" last="Saha">Sukanta Saha</name>
<affiliation>
<nlm:aff id="A4">Queensland Centre for Mental Health Research, and Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Aguilar Gaxiola, Sergio" sort="Aguilar Gaxiola, Sergio" uniqKey="Aguilar Gaxiola S" first="Sergio" last="Aguilar-Gaxiola">Sergio Aguilar-Gaxiola</name>
<affiliation>
<nlm:aff id="A5">Center for Reducing Health Disparities, UC Davis Health System, Sacramento, California, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Al Hamzawi, Ali" sort="Al Hamzawi, Ali" uniqKey="Al Hamzawi A" first="Ali" last="Al-Hamzawi">Ali Al-Hamzawi</name>
<affiliation>
<nlm:aff id="A6">College of Medicine, Al-Qadisiya University, Diwaniya governorate, Iraq</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Andrade, Laura H" sort="Andrade, Laura H" uniqKey="Andrade L" first="Laura H." last="Andrade">Laura H. Andrade</name>
<affiliation>
<nlm:aff id="A7">Section of Psychiatric Epidemiology - LIM 23, Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Bromet, Evelyn J" sort="Bromet, Evelyn J" uniqKey="Bromet E" first="Evelyn J." last="Bromet">Evelyn J. Bromet</name>
<affiliation>
<nlm:aff id="A8">Department of Psychiatry, Stony Brook University School of Medicine, Stony Brook, New York, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Bruffaerts, Ronny" sort="Bruffaerts, Ronny" uniqKey="Bruffaerts R" first="Ronny" last="Bruffaerts">Ronny Bruffaerts</name>
<affiliation>
<nlm:aff id="A9">Universitair Psychiatrisch Centrum - Katholieke Universiteit Leuven (UPC-KUL), Campus Gasthuisberg, Leuven, Belgium</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Chatterji, Somnath" sort="Chatterji, Somnath" uniqKey="Chatterji S" first="Somnath" last="Chatterji">Somnath Chatterji</name>
<affiliation>
<nlm:aff id="A10">Department of Information, Evidence and Research, World Health Organization, Geneva, Switzerland</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Degenhardt, Louisa" sort="Degenhardt, Louisa" uniqKey="Degenhardt L" first="Louisa" last="Degenhardt">Louisa Degenhardt</name>
<affiliation>
<nlm:aff id="A11">National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="De Girolamo, Giovanni" sort="De Girolamo, Giovanni" uniqKey="De Girolamo G" first="Giovanni" last="De Girolamo">Giovanni De Girolamo</name>
<affiliation>
<nlm:aff id="A12">Unit of Epidemiological and Evaluation Psychiatry, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS)-St. John of God Clinical Research Centre, Via Pilastroni 4, Brescia, Italy</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="De Jonge, Peter" sort="De Jonge, Peter" uniqKey="De Jonge P" first="Peter" last="De Jonge">Peter De Jonge</name>
<affiliation>
<nlm:aff id="A13">Developmental Psychology, Department of Psychology, Rijksuniversiteit Groningen, Groningen, NL; Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University Medical</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Fayyad, John" sort="Fayyad, John" uniqKey="Fayyad J" first="John" last="Fayyad">John Fayyad</name>
<affiliation>
<nlm:aff id="A14">Institute for Development, Research, Advocacy & Applied Care (IDRAAC), Beirut, Lebanon</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Florescu, Silvia" sort="Florescu, Silvia" uniqKey="Florescu S" first="Silvia" last="Florescu">Silvia Florescu</name>
<affiliation>
<nlm:aff id="A15">National School of Public Health, Management and Professional Development, Bucharest, Romania</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Gureje, Oye" sort="Gureje, Oye" uniqKey="Gureje O" first="Oye" last="Gureje">Oye Gureje</name>
<affiliation>
<nlm:aff id="A16">Department of Psychiatry, University College Hospital, Ibadan, Nigeria</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Haro, Josep M" sort="Haro, Josep M" uniqKey="Haro J" first="Josep M." last="Haro">Josep M. Haro</name>
<affiliation>
<nlm:aff id="A17">Parc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hu, Chiyi" sort="Hu, Chiyi" uniqKey="Hu C" first="Chiyi" last="Hu">Chiyi Hu</name>
<affiliation>
<nlm:aff id="A18">Shenzhen Institute of Mental Health & Shenzhen Kangning Hospital, Shenzhen, China</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Karam, Elie G" sort="Karam, Elie G" uniqKey="Karam E" first="Elie G." last="Karam">Elie G. Karam</name>
<affiliation>
<nlm:aff id="A19">Department of Psychiatry and Clinical Psychology, Faculty of Medicine, Balamand University, Beirut, Lebanon; Department of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Beirut, Lebanon; Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut, Lebanon</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kovess Masfety, Viviane" sort="Kovess Masfety, Viviane" uniqKey="Kovess Masfety V" first="Viviane" last="Kovess-Masfety">Viviane Kovess-Masfety</name>
<affiliation>
<nlm:aff id="A20">Ecole des Hautes Etudes en Santé Publique (EHESP), EA 4057 Paris Descartes University,Paris, France</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Lee, Sing" sort="Lee, Sing" uniqKey="Lee S" first="Sing" last="Lee">Sing Lee</name>
<affiliation>
<nlm:aff id="A21">Department of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Medina Mora, Maria E" sort="Medina Mora, Maria E" uniqKey="Medina Mora M" first="Maria E." last="Medina-Mora">Maria E. Medina-Mora</name>
<affiliation>
<nlm:aff id="A22">National Institute of Psychiatry Ramón de la Fuente, Mexico City, Mexico</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Ojagbemi, Akin" sort="Ojagbemi, Akin" uniqKey="Ojagbemi A" first="Akin" last="Ojagbemi">Akin Ojagbemi</name>
<affiliation>
<nlm:aff id="A23">College of Medicine, University of Ibadan; University College Hospital, Ibadan, Nigeria</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Pennell, Beth Ellen" sort="Pennell, Beth Ellen" uniqKey="Pennell B" first="Beth-Ellen" last="Pennell">Beth-Ellen Pennell</name>
<affiliation>
<nlm:aff id="A24">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Posada Villa, Jose" sort="Posada Villa, Jose" uniqKey="Posada Villa J" first="Jose" last="Posada-Villa">Jose Posada-Villa</name>
<affiliation>
<nlm:aff id="A25">Colegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota, Colombia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Scott, Kate M" sort="Scott, Kate M" uniqKey="Scott K" first="Kate M." last="Scott">Kate M. Scott</name>
<affiliation>
<nlm:aff id="A26">Department of Psychological Medicine, University of Otago, Dunedin, Otago, New Zealand</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Stagnaro, Juan Carlos" sort="Stagnaro, Juan Carlos" uniqKey="Stagnaro J" first="Juan Carlos" last="Stagnaro">Juan Carlos Stagnaro</name>
<affiliation>
<nlm:aff id="A27">Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Argentina</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kendler, Kenneth S" sort="Kendler, Kenneth S" uniqKey="Kendler K" first="Kenneth S." last="Kendler">Kenneth S. Kendler</name>
<affiliation>
<nlm:aff id="A28">Department of Psychiatry Virginia Commonwealth University, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kessler, Ronald C" sort="Kessler, Ronald C" uniqKey="Kessler R" first="Ronald C." last="Kessler">Ronald C. Kessler</name>
<affiliation>
<nlm:aff id="A29">Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Mcgrath, John J" sort="Mcgrath, John J" uniqKey="Mcgrath J" first="John J." last="Mcgrath">John J. Mcgrath</name>
<affiliation>
<nlm:aff id="A30">Queensland Centre for Mental Health Research, and Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia; and National Centre for Register-based Research, Aarhus BSS, Aarhus University, Aarhus, Denmark</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Acta psychiatrica Scandinavica</title>
<idno type="ISSN">0001-690X</idno>
<idno type="eISSN">1600-0447</idno>
<imprint>
<date when="2017">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<sec id="S1">
<title>Objective</title>
<p id="P1">While psychotic experiences (PEs) are known to be associated with a range of mental and general medical disorders, little is known about the association between PEs and measures of disability. We aimed to investigate this question using the World Mental Health surveys.</p>
</sec>
<sec id="S2">
<title>Method</title>
<p id="P2">Lifetime occurrences of 6 types of PEs were assessed along with 21 mental disorders and 14 general medical conditions. Disability was assessed with a modified version of the WHO Disability Assessment Schedule. Descriptive statistics and logistic regression models were used to investigate the association between PEs and high disability scores (top quartile) with various adjustments.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">Respondents with PEs were more likely to have top quartile scores on global disability than respondents without PEs (19.1% vs. 7.5%; χ
<sup>2</sup>
= 190.1, p<.001) as well as greater likelihood of cognitive, social, and role impairment. Relationships persisted in each adjusted model. A significant dose-response relationship was also found for the PE type measures with most of these outcomes.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P4">Psychotic experiences are associated with disability measures with a dose response relationship. These results are consistent with the view that PEs are associated with disability regardless of the presence of comorbid mental or general medical disorders.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-journal-id">0370364</journal-id>
<journal-id journal-id-type="pubmed-jr-id">192</journal-id>
<journal-id journal-id-type="nlm-ta">Acta Psychiatr Scand</journal-id>
<journal-id journal-id-type="iso-abbrev">Acta Psychiatr Scand</journal-id>
<journal-title-group>
<journal-title>Acta psychiatrica Scandinavica</journal-title>
</journal-title-group>
<issn pub-type="ppub">0001-690X</issn>
<issn pub-type="epub">1600-0447</issn>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">28542726</article-id>
<article-id pub-id-type="pmc">5664954</article-id>
<article-id pub-id-type="doi">10.1111/acps.12749</article-id>
<article-id pub-id-type="manuscript">NIHMS915739</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Navarro-Mateu</surname>
<given-names>Fernando</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Alonso</surname>
<given-names>Jordi</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lim</surname>
<given-names>Carmen C. W.</given-names>
</name>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Saha</surname>
<given-names>Sukanta</given-names>
</name>
<xref ref-type="aff" rid="A4">4</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Aguilar-Gaxiola</surname>
<given-names>Sergio</given-names>
</name>
<xref ref-type="aff" rid="A5">5</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Al-Hamzawi</surname>
<given-names>Ali</given-names>
</name>
<xref ref-type="aff" rid="A6">6</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Andrade</surname>
<given-names>Laura H.</given-names>
</name>
<xref ref-type="aff" rid="A7">7</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bromet</surname>
<given-names>Evelyn J.</given-names>
</name>
<xref ref-type="aff" rid="A8">8</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bruffaerts</surname>
<given-names>Ronny</given-names>
</name>
<xref ref-type="aff" rid="A9">9</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Chatterji</surname>
<given-names>Somnath</given-names>
</name>
<xref ref-type="aff" rid="A10">10</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Degenhardt</surname>
<given-names>Louisa</given-names>
</name>
<xref ref-type="aff" rid="A11">11</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>de Girolamo</surname>
<given-names>Giovanni</given-names>
</name>
<xref ref-type="aff" rid="A12">12</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>de Jonge</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="A13">13</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Fayyad</surname>
<given-names>John</given-names>
</name>
<xref ref-type="aff" rid="A14">14</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Florescu</surname>
<given-names>Silvia</given-names>
</name>
<xref ref-type="aff" rid="A15">15</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Gureje</surname>
<given-names>Oye</given-names>
</name>
<xref ref-type="aff" rid="A16">16</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Haro</surname>
<given-names>Josep M.</given-names>
</name>
<xref ref-type="aff" rid="A17">17</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hu</surname>
<given-names>Chiyi</given-names>
</name>
<xref ref-type="aff" rid="A18">18</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Karam</surname>
<given-names>Elie G.</given-names>
</name>
<xref ref-type="aff" rid="A19">19</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kovess-Masfety</surname>
<given-names>Viviane</given-names>
</name>
<xref ref-type="aff" rid="A20">20</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lee</surname>
<given-names>Sing</given-names>
</name>
<xref ref-type="aff" rid="A21">21</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Medina-Mora</surname>
<given-names>Maria E.</given-names>
</name>
<xref ref-type="aff" rid="A22">22</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ojagbemi</surname>
<given-names>Akin</given-names>
</name>
<xref ref-type="aff" rid="A23">23</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Pennell</surname>
<given-names>Beth-Ellen</given-names>
</name>
<xref ref-type="aff" rid="A24">24</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Posada-Villa</surname>
<given-names>Jose</given-names>
</name>
<xref ref-type="aff" rid="A25">25</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Scott</surname>
<given-names>Kate M.</given-names>
</name>
<xref ref-type="aff" rid="A26">26</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Stagnaro</surname>
<given-names>Juan Carlos</given-names>
</name>
<xref ref-type="aff" rid="A27">27</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kendler</surname>
<given-names>Kenneth S.</given-names>
</name>
<xref ref-type="aff" rid="A28">28</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kessler</surname>
<given-names>Ronald C.</given-names>
</name>
<xref ref-type="aff" rid="A29">29</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>McGrath</surname>
<given-names>John J.</given-names>
</name>
<xref ref-type="aff" rid="A30">30</xref>
</contrib>
<on-behalf-of>on behalf of the WHO World Mental Health Survey Collaborators</on-behalf-of>
</contrib-group>
<aff id="A1">
<label>1</label>
UDIF-SM, Subdirección General de Planificación, Innovación y Cronicidad, Servicio Murciano de Salud. IMIB-Arrixaca. CIBERESP-Murcia, Murcia, Spain</aff>
<aff id="A2">
<label>2</label>
Health Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain; Pompeu Fabra University (UPF), Barcelona, Spain; and CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</aff>
<aff id="A3">
<label>3</label>
Queensland Brain Institute, The University of Queensland, St. Lucia, Queensland, Australia</aff>
<aff id="A4">
<label>4</label>
Queensland Centre for Mental Health Research, and Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia</aff>
<aff id="A5">
<label>5</label>
Center for Reducing Health Disparities, UC Davis Health System, Sacramento, California, USA</aff>
<aff id="A6">
<label>6</label>
College of Medicine, Al-Qadisiya University, Diwaniya governorate, Iraq</aff>
<aff id="A7">
<label>7</label>
Section of Psychiatric Epidemiology - LIM 23, Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil</aff>
<aff id="A8">
<label>8</label>
Department of Psychiatry, Stony Brook University School of Medicine, Stony Brook, New York, USA</aff>
<aff id="A9">
<label>9</label>
Universitair Psychiatrisch Centrum - Katholieke Universiteit Leuven (UPC-KUL), Campus Gasthuisberg, Leuven, Belgium</aff>
<aff id="A10">
<label>10</label>
Department of Information, Evidence and Research, World Health Organization, Geneva, Switzerland</aff>
<aff id="A11">
<label>11</label>
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia</aff>
<aff id="A12">
<label>12</label>
Unit of Epidemiological and Evaluation Psychiatry, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS)-St. John of God Clinical Research Centre, Via Pilastroni 4, Brescia, Italy</aff>
<aff id="A13">
<label>13</label>
Developmental Psychology, Department of Psychology, Rijksuniversiteit Groningen, Groningen, NL; Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University Medical</aff>
<aff id="A14">
<label>14</label>
Institute for Development, Research, Advocacy & Applied Care (IDRAAC), Beirut, Lebanon</aff>
<aff id="A15">
<label>15</label>
National School of Public Health, Management and Professional Development, Bucharest, Romania</aff>
<aff id="A16">
<label>16</label>
Department of Psychiatry, University College Hospital, Ibadan, Nigeria</aff>
<aff id="A17">
<label>17</label>
Parc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain</aff>
<aff id="A18">
<label>18</label>
Shenzhen Institute of Mental Health & Shenzhen Kangning Hospital, Shenzhen, China</aff>
<aff id="A19">
<label>19</label>
Department of Psychiatry and Clinical Psychology, Faculty of Medicine, Balamand University, Beirut, Lebanon; Department of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Beirut, Lebanon; Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut, Lebanon</aff>
<aff id="A20">
<label>20</label>
Ecole des Hautes Etudes en Santé Publique (EHESP), EA 4057 Paris Descartes University,Paris, France</aff>
<aff id="A21">
<label>21</label>
Department of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong</aff>
<aff id="A22">
<label>22</label>
National Institute of Psychiatry Ramón de la Fuente, Mexico City, Mexico</aff>
<aff id="A23">
<label>23</label>
College of Medicine, University of Ibadan; University College Hospital, Ibadan, Nigeria</aff>
<aff id="A24">
<label>24</label>
Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA</aff>
<aff id="A25">
<label>25</label>
Colegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota, Colombia</aff>
<aff id="A26">
<label>26</label>
Department of Psychological Medicine, University of Otago, Dunedin, Otago, New Zealand</aff>
<aff id="A27">
<label>27</label>
Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Argentina</aff>
<aff id="A28">
<label>28</label>
Department of Psychiatry Virginia Commonwealth University, USA</aff>
<aff id="A29">
<label>29</label>
Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA</aff>
<aff id="A30">
<label>30</label>
Queensland Centre for Mental Health Research, and Queensland Brain Institute, University of Queensland, St. Lucia, Queensland, Australia; and National Centre for Register-based Research, Aarhus BSS, Aarhus University, Aarhus, Denmark</aff>
<author-notes>
<corresp id="FN1">Corresponding author: Professor John McGrath, Queensland Brain Institute, The University of Queensland, St Lucia, Queensland 4076, Australia.
<email>j.mcgrath@uq.edu.au</email>
, Phone: +61 7 3271 8694, Fax: +61 7 3271 8698</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted">
<day>27</day>
<month>10</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>25</day>
<month>5</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="ppub">
<month>7</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>01</day>
<month>11</month>
<year>2017</year>
</pub-date>
<volume>136</volume>
<issue>1</issue>
<fpage>74</fpage>
<lpage>84</lpage>
<pmc-comment>elocation-id from pubmed: 10.1111/acps.12749</pmc-comment>
<abstract>
<sec id="S1">
<title>Objective</title>
<p id="P1">While psychotic experiences (PEs) are known to be associated with a range of mental and general medical disorders, little is known about the association between PEs and measures of disability. We aimed to investigate this question using the World Mental Health surveys.</p>
</sec>
<sec id="S2">
<title>Method</title>
<p id="P2">Lifetime occurrences of 6 types of PEs were assessed along with 21 mental disorders and 14 general medical conditions. Disability was assessed with a modified version of the WHO Disability Assessment Schedule. Descriptive statistics and logistic regression models were used to investigate the association between PEs and high disability scores (top quartile) with various adjustments.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">Respondents with PEs were more likely to have top quartile scores on global disability than respondents without PEs (19.1% vs. 7.5%; χ
<sup>2</sup>
= 190.1, p<.001) as well as greater likelihood of cognitive, social, and role impairment. Relationships persisted in each adjusted model. A significant dose-response relationship was also found for the PE type measures with most of these outcomes.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P4">Psychotic experiences are associated with disability measures with a dose response relationship. These results are consistent with the view that PEs are associated with disability regardless of the presence of comorbid mental or general medical disorders.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Psychotic experiences</kwd>
<kwd>disability</kwd>
<kwd>World Mental Health Survey</kwd>
<kwd>WHODAS</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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