EFFECT OF COMMUNITY NURSE FOLLOW-UP WHEN TREATING ALCOHOL DEPENDENCE WITH ACAMPROSATE
Identifieur interne : 000927 ( Istex/Curation ); précédent : 000926; suivant : 000928EFFECT OF COMMUNITY NURSE FOLLOW-UP WHEN TREATING ALCOHOL DEPENDENCE WITH ACAMPROSATE
Auteurs : I. Pelc [Belgique] ; C. Hanak ; I. Baert ; C. Houtain ; P. Lehert [Australie] ; F. Landron [France] ; P. VerbanckSource :
- Alcohol and Alcoholism [ 0735-0414 ] ; 2005-NaN.
Descripteurs français
- Wicri :
- topic : Alcoolisme, Situation de famille, Protocole.
English descriptors
- KwdEn :
- Absolute abstinence, Abstinence, Abstinence outcome, Abstinence rates, Acamprosate, Adverse event protocol violation, Adverse events, Alcohol consumption, Alcohol dependence, Alcoholism, Better compliance, Body weight, Brugmann university hospital, Cadp, Clinical trial, Community nurse, Community nurse support, Cumulative abstinence duration, Cumulative abstinence duration proportion, Determinant, Detoxification, Detoxification programme, Detoxified patients, Education level, Educational status, European addiction research, Experimental research, First drink, Gastrointestinal events, Gender, General practitioner, Hospital outpatient clinic, Important determinant, Male patients, Marital status, Medication, Nurse group, Open study, Outpatient, Outpatient treatment, Patient flow, Patient request loss, Pelc, Previous month, Programme, Protocol, Protocol violation patient request, Psychiatry department, Psychosocial, Psychosocial intervention, Psychosocial support, Psychosocial treatment, Randomized, Randomized patients, Rehabilitation programmes, Significant difference, Social support, Study centre, Study period, Study visit, Subgroup, Treatment group, Treatment groups, Treatment retention, Universitaire brugmann.
- Teeft :
- Absolute abstinence, Abstinence, Abstinence outcome, Abstinence rates, Acamprosate, Adverse event protocol violation, Adverse events, Alcohol consumption, Alcohol dependence, Alcoholism, Better compliance, Body weight, Brugmann university hospital, Cadp, Clinical trial, Community nurse, Community nurse support, Cumulative abstinence duration, Cumulative abstinence duration proportion, Determinant, Detoxification, Detoxification programme, Detoxified patients, Education level, Educational status, European addiction research, Experimental research, First drink, Gastrointestinal events, Gender, General practitioner, Hospital outpatient clinic, Important determinant, Male patients, Marital status, Medication, Nurse group, Open study, Outpatient, Outpatient treatment, Patient flow, Patient request loss, Pelc, Previous month, Programme, Protocol, Protocol violation patient request, Psychiatry department, Psychosocial, Psychosocial intervention, Psychosocial support, Psychosocial treatment, Randomized, Randomized patients, Rehabilitation programmes, Significant difference, Social support, Study centre, Study period, Study visit, Subgroup, Treatment group, Treatment groups, Treatment retention, Universitaire brugmann.
Abstract
Aims: To measure the effect of community nurse follow-up on abstinence and retention rates in the outpatient treatment of alcohol-dependent patients treated with acamprosate. Methods: Recently detoxified alcohol-dependent patients were prescribed acamprosate for 26 weeks and randomized to either physician-only follow-up, or physician plus regular visits from a community nurse. Drinking behaviour in the next 26 weeks was assessed at monthly visits to non-blind clinicians. Results: The cumulative abstinence duration proportion (CADP) was significantly longer in (P = 0.03) the subjects who had received community nurse support (0.57) than in those who had not (0.39). This might, in part, be an artefact of the higher retention rate among those followed up by the nurse, in that, the method of calculating CADP allocates 100% days of drinking for the month before a failed attendance. Differences favouring nurse in the follow-up were seen for time to first drink, and clinical global impression. Conclusions: For recently detoxified alcohol-dependent patients treated with acamprosate, follow-up by a community nurse improves patient retention and probably also improves the 6-month drinking outcome.
Url:
DOI: 10.1093/alcalc/agh136
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C. Hanak<affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation>Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">EFFECT OF COMMUNITY NURSE FOLLOW-UP WHEN TREATING ALCOHOL DEPENDENCE WITH ACAMPROSATE</title><author><name sortKey="Pelc, I" sort="Pelc, I" uniqKey="Pelc I" first="I." last="Pelc">I. Pelc</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation wicri:level="1"><mods:affiliation>Author to whom correspondence should be addressed at: I. Pelc, Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium. Tel.: +32 02 477 27 05; Fax: +32 02 477 35 14; E-mail: isidore.pelc@chu-brugmann.be</mods:affiliation><country wicri:rule="url">Belgique</country><wicri:regionArea>Author to whom correspondence should be addressed at: I. Pelc, Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles</wicri:regionArea></affiliation></author><author><name sortKey="Hanak, C" sort="Hanak, C" uniqKey="Hanak C" first="C." last="Hanak">C. Hanak</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Baert, I" sort="Baert, I" uniqKey="Baert I" first="I." last="Baert">I. Baert</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Houtain, C" sort="Houtain, C" uniqKey="Houtain C" first="C." last="Houtain">C. Houtain</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Lehert, P" sort="Lehert, P" uniqKey="Lehert P" first="P." last="Lehert">P. Lehert</name><affiliation wicri:level="4"><mods:affiliation>The Faculty of Medicine, University of Melbourne, Melbourne, Australia and Department of Statistics, FUCAM, Mons, Belgium and</mods:affiliation><orgName type="university">Université de Melbourne</orgName><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Landron, F" sort="Landron, F" uniqKey="Landron F" first="F." last="Landron">F. Landron</name><affiliation wicri:level="1"><mods:affiliation>Merck SA, 37, rue St Romain, 69379 Lyon Cedex 08, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Merck SA, 37, rue St Romain, 69379 Lyon Cedex 08</wicri:regionArea></affiliation></author><author><name sortKey="Verbanck, P" sort="Verbanck, P" uniqKey="Verbanck P" first="P." last="Verbanck">P. Verbanck</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3067EC6D2F5544244AA23A319A610E5B754A95F3</idno><date when="2005" year="2005">2005</date><idno type="doi">10.1093/alcalc/agh136</idno><idno type="url">https://api.istex.fr/document/3067EC6D2F5544244AA23A319A610E5B754A95F3/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000927</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000927</idno><idno type="wicri:Area/Istex/Curation">000927</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">EFFECT OF COMMUNITY NURSE FOLLOW-UP WHEN TREATING ALCOHOL DEPENDENCE WITH ACAMPROSATE</title><author><name sortKey="Pelc, I" sort="Pelc, I" uniqKey="Pelc I" first="I." last="Pelc">I. Pelc</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation></affiliation><affiliation wicri:level="1"><mods:affiliation>Author to whom correspondence should be addressed at: I. Pelc, Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium. Tel.: +32 02 477 27 05; Fax: +32 02 477 35 14; E-mail: isidore.pelc@chu-brugmann.be</mods:affiliation><country wicri:rule="url">Belgique</country><wicri:regionArea>Author to whom correspondence should be addressed at: I. Pelc, Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles</wicri:regionArea></affiliation></author><author><name sortKey="Hanak, C" sort="Hanak, C" uniqKey="Hanak C" first="C." last="Hanak">C. Hanak</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Baert, I" sort="Baert, I" uniqKey="Baert I" first="I." last="Baert">I. Baert</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Houtain, C" sort="Houtain, C" uniqKey="Houtain C" first="C." last="Houtain">C. Houtain</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Lehert, P" sort="Lehert, P" uniqKey="Lehert P" first="P." last="Lehert">P. Lehert</name><affiliation wicri:level="4"><mods:affiliation>The Faculty of Medicine, University of Melbourne, Melbourne, Australia and Department of Statistics, FUCAM, Mons, Belgium and</mods:affiliation><orgName type="university">Université de Melbourne</orgName><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Landron, F" sort="Landron, F" uniqKey="Landron F" first="F." last="Landron">F. Landron</name><affiliation wicri:level="1"><mods:affiliation>Merck SA, 37, rue St Romain, 69379 Lyon Cedex 08, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Merck SA, 37, rue St Romain, 69379 Lyon Cedex 08</wicri:regionArea></affiliation></author><author><name sortKey="Verbanck, P" sort="Verbanck, P" uniqKey="Verbanck P" first="P." last="Verbanck">P. Verbanck</name><affiliation><mods:affiliation>Psychiatry Department, Hôpital Universitaire Brugmann, Université Libre de Bruxelles, Place A. van Gehuchten 4, 1020 Bruxelles, Belgium,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j">Alcohol and Alcoholism</title><title level="j" type="abbrev">Alcohol and Alcoholism</title><idno type="ISSN">0735-0414</idno><idno type="eISSN">1464-3502</idno><imprint><publisher>Oxford University Press</publisher><date type="published" when="2005-NaN">2005-NaN</date><biblScope unit="volume">40</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="302">302</biblScope><biblScope unit="page" to="307">307</biblScope></imprint><idno type="ISSN">0735-0414</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0735-0414</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Absolute abstinence</term><term>Abstinence</term><term>Abstinence outcome</term><term>Abstinence rates</term><term>Acamprosate</term><term>Adverse event protocol violation</term><term>Adverse events</term><term>Alcohol consumption</term><term>Alcohol dependence</term><term>Alcoholism</term><term>Better compliance</term><term>Body weight</term><term>Brugmann university hospital</term><term>Cadp</term><term>Clinical trial</term><term>Community nurse</term><term>Community nurse support</term><term>Cumulative abstinence duration</term><term>Cumulative abstinence duration proportion</term><term>Determinant</term><term>Detoxification</term><term>Detoxification programme</term><term>Detoxified patients</term><term>Education level</term><term>Educational status</term><term>European addiction research</term><term>Experimental research</term><term>First drink</term><term>Gastrointestinal events</term><term>Gender</term><term>General practitioner</term><term>Hospital outpatient clinic</term><term>Important determinant</term><term>Male patients</term><term>Marital status</term><term>Medication</term><term>Nurse group</term><term>Open study</term><term>Outpatient</term><term>Outpatient treatment</term><term>Patient flow</term><term>Patient request loss</term><term>Pelc</term><term>Previous month</term><term>Programme</term><term>Protocol</term><term>Protocol violation patient request</term><term>Psychiatry department</term><term>Psychosocial</term><term>Psychosocial intervention</term><term>Psychosocial support</term><term>Psychosocial treatment</term><term>Randomized</term><term>Randomized patients</term><term>Rehabilitation programmes</term><term>Significant difference</term><term>Social support</term><term>Study centre</term><term>Study period</term><term>Study visit</term><term>Subgroup</term><term>Treatment group</term><term>Treatment groups</term><term>Treatment retention</term><term>Universitaire brugmann</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Absolute abstinence</term><term>Abstinence</term><term>Abstinence outcome</term><term>Abstinence rates</term><term>Acamprosate</term><term>Adverse event protocol violation</term><term>Adverse events</term><term>Alcohol consumption</term><term>Alcohol dependence</term><term>Alcoholism</term><term>Better compliance</term><term>Body weight</term><term>Brugmann university hospital</term><term>Cadp</term><term>Clinical trial</term><term>Community nurse</term><term>Community nurse support</term><term>Cumulative abstinence duration</term><term>Cumulative abstinence duration proportion</term><term>Determinant</term><term>Detoxification</term><term>Detoxification programme</term><term>Detoxified patients</term><term>Education level</term><term>Educational status</term><term>European addiction research</term><term>Experimental research</term><term>First drink</term><term>Gastrointestinal events</term><term>Gender</term><term>General practitioner</term><term>Hospital outpatient clinic</term><term>Important determinant</term><term>Male patients</term><term>Marital status</term><term>Medication</term><term>Nurse group</term><term>Open study</term><term>Outpatient</term><term>Outpatient treatment</term><term>Patient flow</term><term>Patient request loss</term><term>Pelc</term><term>Previous month</term><term>Programme</term><term>Protocol</term><term>Protocol violation patient request</term><term>Psychiatry department</term><term>Psychosocial</term><term>Psychosocial intervention</term><term>Psychosocial support</term><term>Psychosocial treatment</term><term>Randomized</term><term>Randomized patients</term><term>Rehabilitation programmes</term><term>Significant difference</term><term>Social support</term><term>Study centre</term><term>Study period</term><term>Study visit</term><term>Subgroup</term><term>Treatment group</term><term>Treatment groups</term><term>Treatment retention</term><term>Universitaire brugmann</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Alcoolisme</term><term>Situation de famille</term><term>Protocole</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Aims: To measure the effect of community nurse follow-up on abstinence and retention rates in the outpatient treatment of alcohol-dependent patients treated with acamprosate. Methods: Recently detoxified alcohol-dependent patients were prescribed acamprosate for 26 weeks and randomized to either physician-only follow-up, or physician plus regular visits from a community nurse. Drinking behaviour in the next 26 weeks was assessed at monthly visits to non-blind clinicians. Results: The cumulative abstinence duration proportion (CADP) was significantly longer in (P = 0.03) the subjects who had received community nurse support (0.57) than in those who had not (0.39). This might, in part, be an artefact of the higher retention rate among those followed up by the nurse, in that, the method of calculating CADP allocates 100% days of drinking for the month before a failed attendance. Differences favouring nurse in the follow-up were seen for time to first drink, and clinical global impression. Conclusions: For recently detoxified alcohol-dependent patients treated with acamprosate, follow-up by a community nurse improves patient retention and probably also improves the 6-month drinking outcome.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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