Intramyocellular lipid variations in active older men: relationship with aerobic fitness
Identifieur interne : 002818 ( Istex/Corpus ); précédent : 002817; suivant : 002819Intramyocellular lipid variations in active older men: relationship with aerobic fitness
Auteurs : D. Rouffet ; C. Villars ; R. Fissoune ; D. Sappey-Marinier ; M. Laville ; D. Ibarrola ; M. Sothier ; M. Monnet ; M. Ovize ; M. Bonnefoy ; C. Boesch ; E. Canet-SoulasSource :
- Acta Physiologica [ 1748-1708 ] ; 2013-03.
English descriptors
- KwdEn :
- Acta, Acta physiol, Aerobic, Aerobic capacities, Authors acta physiologica, Boesch, Clin endocrinol metab, Diet intervention, Emcl resonances, Endocrinol, Exerc, Exercise interventions, France department, Imcl, Imcl concentra, Imcl content, Imcl level, Imcl mobilization, Imcl stores, Imcl variations, Imclfdr, Imclfdr_ex, Imclfdr_ex mmol, Imclhf, Imclhf_ex, Initial store, Insulin, Insulin resistance, Insulin sensitivity, Intramyocellular, Intramyocellular lipid, Intramyocellular lipid content, Intramyocellular lipids, Lipid, Lyon, Machann, Metab, Mmol, Morning imcl stores, Normal protein, Older adults, Optimal splitting, Physical activity, Physical exercise, Physiol, Physiol endocrinol metab, Physiologica, Rouffet, Sports exerc, Tness, Wide range, Young adults, Young athletes, Zehnder.
- Teeft :
- Acta, Acta physiol, Aerobic, Aerobic capacities, Authors acta physiologica, Boesch, Clin endocrinol metab, Diet intervention, Emcl resonances, Endocrinol, Exerc, Exercise interventions, France department, Imcl, Imcl concentra, Imcl content, Imcl level, Imcl mobilization, Imcl stores, Imcl variations, Imclfdr, Imclfdr_ex, Imclfdr_ex mmol, Imclhf, Imclhf_ex, Initial store, Insulin, Insulin resistance, Insulin sensitivity, Intramyocellular, Intramyocellular lipid, Intramyocellular lipid content, Intramyocellular lipids, Lipid, Lyon, Machann, Metab, Mmol, Morning imcl stores, Normal protein, Older adults, Optimal splitting, Physical activity, Physical exercise, Physiol, Physiol endocrinol metab, Physiologica, Rouffet, Sports exerc, Tness, Wide range, Young adults, Young athletes, Zehnder.
Abstract
Intramyocellular lipid (IMCL) variations in older men are poorly explored. In young adults, IMCL can be influenced by both diet and exercise interventions; this flexibility is related to aerobic fitness. We evaluated in active older adults the influence of maximal aerobic capacity on short‐term diet and exercise‐induced variations in IMCL stores.
Url:
DOI: 10.1111/apha.12045
Links to Exploration step
ISTEX:D7228EAC54788E1C7C4519490829B4139D4F077ALe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Intramyocellular lipid variations in active older men: relationship with aerobic fitness</title><author><name sortKey="Rouffet, D" sort="Rouffet, D" uniqKey="Rouffet D" first="D." last="Rouffet">D. Rouffet</name><affiliation><mods:affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>ISEAL, Victoria University, Vic., Melbourne, Australia</mods:affiliation></affiliation></author><author><name sortKey="Villars, C" sort="Villars, C" uniqKey="Villars C" first="C." last="Villars">C. Villars</name><affiliation><mods:affiliation>University Lyon 1, CRIS, EA647, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Fissoune, R" sort="Fissoune, R" uniqKey="Fissoune R" first="R." last="Fissoune">R. Fissoune</name><affiliation><mods:affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Sappey Arinier, D" sort="Sappey Arinier, D" uniqKey="Sappey Arinier D" first="D." last="Sappey-Marinier">D. Sappey-Marinier</name><affiliation><mods:affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>CERMEP, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Laville, M" sort="Laville, M" uniqKey="Laville M" first="M." last="Laville">M. Laville</name><affiliation><mods:affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Ibarrola, D" sort="Ibarrola, D" uniqKey="Ibarrola D" first="D." last="Ibarrola">D. Ibarrola</name><affiliation><mods:affiliation>CERMEP, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Sothier, M" sort="Sothier, M" uniqKey="Sothier M" first="M." last="Sothier">M. Sothier</name><affiliation><mods:affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Monnet, M" sort="Monnet, M" uniqKey="Monnet M" first="M." last="Monnet">M. Monnet</name><affiliation><mods:affiliation>Department of Cardiology, Lyon EST Hospital, Hospices Civils of Lyon, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Ovize, M" sort="Ovize, M" uniqKey="Ovize M" first="M." last="Ovize">M. Ovize</name><affiliation><mods:affiliation>Department of Cardiology, Lyon EST Hospital, Hospices Civils of Lyon, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Bonnefoy, M" sort="Bonnefoy, M" uniqKey="Bonnefoy M" first="M." last="Bonnefoy">M. Bonnefoy</name><affiliation><mods:affiliation>Department of Geriatric Medicine, Lyon Sud Hospital, Hospices Civils of Lyon, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Boesch, C" sort="Boesch, C" uniqKey="Boesch C" first="C." last="Boesch">C. Boesch</name><affiliation><mods:affiliation>Department of Clinical Research, University of Bern, Bern, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Canet Oulas, E" sort="Canet Oulas, E" uniqKey="Canet Oulas E" first="E." last="Canet-Soulas">E. Canet-Soulas</name><affiliation><mods:affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence: E. Canet‐Soulas, IUF, Université Lyon 1, CarMeN, U1060 INSERM, Campus La Doua, bat. IMBL, 11 avenue Jean Capelle, INSA de Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex, France.E‐mail:</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: emmanuelle.canet@univ-lyon1.fr</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:D7228EAC54788E1C7C4519490829B4139D4F077A</idno><date when="2013" year="2013">2013</date><idno type="doi">10.1111/apha.12045</idno><idno type="url">https://api.istex.fr/document/D7228EAC54788E1C7C4519490829B4139D4F077A/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002818</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002818</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Intramyocellular lipid variations in active older men: relationship with aerobic fitness</title><author><name sortKey="Rouffet, D" sort="Rouffet, D" uniqKey="Rouffet D" first="D." last="Rouffet">D. Rouffet</name><affiliation><mods:affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>ISEAL, Victoria University, Vic., Melbourne, Australia</mods:affiliation></affiliation></author><author><name sortKey="Villars, C" sort="Villars, C" uniqKey="Villars C" first="C." last="Villars">C. Villars</name><affiliation><mods:affiliation>University Lyon 1, CRIS, EA647, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Fissoune, R" sort="Fissoune, R" uniqKey="Fissoune R" first="R." last="Fissoune">R. Fissoune</name><affiliation><mods:affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Sappey Arinier, D" sort="Sappey Arinier, D" uniqKey="Sappey Arinier D" first="D." last="Sappey-Marinier">D. Sappey-Marinier</name><affiliation><mods:affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>CERMEP, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Laville, M" sort="Laville, M" uniqKey="Laville M" first="M." last="Laville">M. Laville</name><affiliation><mods:affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Ibarrola, D" sort="Ibarrola, D" uniqKey="Ibarrola D" first="D." last="Ibarrola">D. Ibarrola</name><affiliation><mods:affiliation>CERMEP, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Sothier, M" sort="Sothier, M" uniqKey="Sothier M" first="M." last="Sothier">M. Sothier</name><affiliation><mods:affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Monnet, M" sort="Monnet, M" uniqKey="Monnet M" first="M." last="Monnet">M. Monnet</name><affiliation><mods:affiliation>Department of Cardiology, Lyon EST Hospital, Hospices Civils of Lyon, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Ovize, M" sort="Ovize, M" uniqKey="Ovize M" first="M." last="Ovize">M. Ovize</name><affiliation><mods:affiliation>Department of Cardiology, Lyon EST Hospital, Hospices Civils of Lyon, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Bonnefoy, M" sort="Bonnefoy, M" uniqKey="Bonnefoy M" first="M." last="Bonnefoy">M. Bonnefoy</name><affiliation><mods:affiliation>Department of Geriatric Medicine, Lyon Sud Hospital, Hospices Civils of Lyon, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Boesch, C" sort="Boesch, C" uniqKey="Boesch C" first="C." last="Boesch">C. Boesch</name><affiliation><mods:affiliation>Department of Clinical Research, University of Bern, Bern, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Canet Oulas, E" sort="Canet Oulas, E" uniqKey="Canet Oulas E" first="E." last="Canet-Soulas">E. Canet-Soulas</name><affiliation><mods:affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence: E. Canet‐Soulas, IUF, Université Lyon 1, CarMeN, U1060 INSERM, Campus La Doua, bat. IMBL, 11 avenue Jean Capelle, INSA de Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex, France.E‐mail:</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: emmanuelle.canet@univ-lyon1.fr</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Acta Physiologica</title><title level="j" type="alt">ACTA PHYSIOLOGICA</title><idno type="ISSN">1748-1708</idno><idno type="eISSN">1748-1716</idno><imprint><biblScope unit="vol">207</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="516">516</biblScope><biblScope unit="page" to="523">523</biblScope><biblScope unit="page-count">8</biblScope><date type="published" when="2013-03">2013-03</date></imprint><idno type="ISSN">1748-1708</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1748-1708</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acta</term><term>Acta physiol</term><term>Aerobic</term><term>Aerobic capacities</term><term>Authors acta physiologica</term><term>Boesch</term><term>Clin endocrinol metab</term><term>Diet intervention</term><term>Emcl resonances</term><term>Endocrinol</term><term>Exerc</term><term>Exercise interventions</term><term>France department</term><term>Imcl</term><term>Imcl concentra</term><term>Imcl content</term><term>Imcl level</term><term>Imcl mobilization</term><term>Imcl stores</term><term>Imcl variations</term><term>Imclfdr</term><term>Imclfdr_ex</term><term>Imclfdr_ex mmol</term><term>Imclhf</term><term>Imclhf_ex</term><term>Initial store</term><term>Insulin</term><term>Insulin resistance</term><term>Insulin sensitivity</term><term>Intramyocellular</term><term>Intramyocellular lipid</term><term>Intramyocellular lipid content</term><term>Intramyocellular lipids</term><term>Lipid</term><term>Lyon</term><term>Machann</term><term>Metab</term><term>Mmol</term><term>Morning imcl stores</term><term>Normal protein</term><term>Older adults</term><term>Optimal splitting</term><term>Physical activity</term><term>Physical exercise</term><term>Physiol</term><term>Physiol endocrinol metab</term><term>Physiologica</term><term>Rouffet</term><term>Sports exerc</term><term>Tness</term><term>Wide range</term><term>Young adults</term><term>Young athletes</term><term>Zehnder</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Acta</term><term>Acta physiol</term><term>Aerobic</term><term>Aerobic capacities</term><term>Authors acta physiologica</term><term>Boesch</term><term>Clin endocrinol metab</term><term>Diet intervention</term><term>Emcl resonances</term><term>Endocrinol</term><term>Exerc</term><term>Exercise interventions</term><term>France department</term><term>Imcl</term><term>Imcl concentra</term><term>Imcl content</term><term>Imcl level</term><term>Imcl mobilization</term><term>Imcl stores</term><term>Imcl variations</term><term>Imclfdr</term><term>Imclfdr_ex</term><term>Imclfdr_ex mmol</term><term>Imclhf</term><term>Imclhf_ex</term><term>Initial store</term><term>Insulin</term><term>Insulin resistance</term><term>Insulin sensitivity</term><term>Intramyocellular</term><term>Intramyocellular lipid</term><term>Intramyocellular lipid content</term><term>Intramyocellular lipids</term><term>Lipid</term><term>Lyon</term><term>Machann</term><term>Metab</term><term>Mmol</term><term>Morning imcl stores</term><term>Normal protein</term><term>Older adults</term><term>Optimal splitting</term><term>Physical activity</term><term>Physical exercise</term><term>Physiol</term><term>Physiol endocrinol metab</term><term>Physiologica</term><term>Rouffet</term><term>Sports exerc</term><term>Tness</term><term>Wide range</term><term>Young adults</term><term>Young athletes</term><term>Zehnder</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">Intramyocellular lipid (IMCL) variations in older men are poorly explored. In young adults, IMCL can be influenced by both diet and exercise interventions; this flexibility is related to aerobic fitness. We evaluated in active older adults the influence of maximal aerobic capacity on short‐term diet and exercise‐induced variations in IMCL stores.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>imcl</json:string><json:string>lipid</json:string><json:string>imclfdr</json:string><json:string>imcl stores</json:string><json:string>physiol</json:string><json:string>intramyocellular</json:string><json:string>tness</json:string><json:string>acta</json:string><json:string>imclhf</json:string><json:string>mmol</json:string><json:string>imcl variations</json:string><json:string>imclfdr_ex</json:string><json:string>zehnder</json:string><json:string>boesch</json:string><json:string>older adults</json:string><json:string>aerobic</json:string><json:string>insulin sensitivity</json:string><json:string>authors acta physiologica</json:string><json:string>imclhf_ex</json:string><json:string>metab</json:string><json:string>physiologica</json:string><json:string>endocrinol</json:string><json:string>physical activity</json:string><json:string>machann</json:string><json:string>acta physiol</json:string><json:string>intramyocellular lipids</json:string><json:string>rouffet</json:string><json:string>exerc</json:string><json:string>physical exercise</json:string><json:string>sports exerc</json:string><json:string>insulin resistance</json:string><json:string>young athletes</json:string><json:string>physiol endocrinol metab</json:string><json:string>optimal splitting</json:string><json:string>emcl resonances</json:string><json:string>initial store</json:string><json:string>young adults</json:string><json:string>diet intervention</json:string><json:string>imcl level</json:string><json:string>morning imcl stores</json:string><json:string>france department</json:string><json:string>normal protein</json:string><json:string>imcl content</json:string><json:string>intramyocellular lipid</json:string><json:string>imcl concentra</json:string><json:string>clin endocrinol metab</json:string><json:string>imcl mobilization</json:string><json:string>aerobic capacities</json:string><json:string>exercise interventions</json:string><json:string>intramyocellular lipid content</json:string><json:string>imclfdr_ex mmol</json:string><json:string>wide range</json:string><json:string>lyon</json:string><json:string>insulin</json:string></teeft></keywords><author><json:item><name>D. Rouffet</name><affiliations><json:string>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</json:string><json:string>ISEAL, Victoria University, Vic., Melbourne, Australia</json:string></affiliations></json:item><json:item><name>C. Villars</name><affiliations><json:string>University Lyon 1, CRIS, EA647, Lyon, France</json:string><json:string>CRNH RA and CENS, University Lyon 1, Lyon, France</json:string></affiliations></json:item><json:item><name>R. Fissoune</name><affiliations><json:string>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</json:string></affiliations></json:item><json:item><name>D. Sappey‐Marinier</name><affiliations><json:string>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</json:string><json:string>CERMEP, Lyon, France</json:string></affiliations></json:item><json:item><name>M. Laville</name><affiliations><json:string>CRNH RA and CENS, University Lyon 1, Lyon, France</json:string></affiliations></json:item><json:item><name>D. Ibarrola</name><affiliations><json:string>CERMEP, Lyon, France</json:string></affiliations></json:item><json:item><name>M. Sothier</name><affiliations><json:string>CRNH RA and CENS, University Lyon 1, Lyon, France</json:string></affiliations></json:item><json:item><name>M.‐F. Monnet</name><affiliations><json:string>Department of Cardiology, Lyon EST Hospital, Hospices Civils of Lyon, Lyon, France</json:string></affiliations></json:item><json:item><name>M. Ovize</name><affiliations><json:string>Department of Cardiology, Lyon EST Hospital, Hospices Civils of Lyon, Lyon, France</json:string></affiliations></json:item><json:item><name>M. Bonnefoy</name><affiliations><json:string>Department of Geriatric Medicine, Lyon Sud Hospital, Hospices Civils of Lyon, Lyon, France</json:string></affiliations></json:item><json:item><name>C. Boesch</name><affiliations><json:string>Department of Clinical Research, University of Bern, Bern, Switzerland</json:string></affiliations></json:item><json:item><name>E. Canet‐Soulas</name><affiliations><json:string>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</json:string><json:string>CRNH RA and CENS, University Lyon 1, Lyon, France</json:string><json:string>Correspondence: E. Canet‐Soulas, IUF, Université Lyon 1, CarMeN, U1060 INSERM, Campus La Doua, bat. IMBL, 11 avenue Jean Capelle, INSA de Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex, France.E‐mail:</json:string><json:string>E-mail: emmanuelle.canet@univ-lyon1.fr</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>exercise</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>lipids</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>magnetic resonance</value></json:item></subject><articleId><json:string>APHA12045</json:string></articleId><arkIstex>ark:/67375/WNG-DVP5MGK8-1</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Intramyocellular lipid (IMCL) variations in older men are poorly explored. In young adults, IMCL can be influenced by both diet and exercise interventions; this flexibility is related to aerobic fitness. We evaluated in active older adults the influence of maximal aerobic capacity on short‐term diet and exercise‐induced variations in IMCL stores.</abstract><qualityIndicators><score>7.612</score><pdfWordCount>5077</pdfWordCount><pdfCharCount>31785</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>8</pdfPageCount><pdfPageSize>595.276 x 793.701 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>51</abstractWordCount><abstractCharCount>348</abstractCharCount><keywordCount>3</keywordCount></qualityIndicators><title>Intramyocellular lipid variations in active older men: relationship with aerobic fitness</title><pmid><json:string>23217190</json:string></pmid><genre><json:string>article</json:string></genre><host><title>Acta Physiologica</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1748-1716</json:string></doi><issn><json:string>1748-1708</json:string></issn><eissn><json:string>1748-1716</json:string></eissn><publisherId><json:string>APHA</json:string></publisherId><volume>207</volume><issue>3</issue><pages><first>516</first><last>523</last><total>8</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Original Article</value></json:item></subject></host><namedEntities><unitex><date><json:string>2012-12-08</json:string><json:string>4659</json:string></date><geogName></geogName><orgName><json:string>Belgium, and Immunotech, Marseille, France</json:string><json:string>Hospital of Lyon</json:string><json:string>Rhone-Alpes Future Foundation</json:string><json:string>Ethics Committee Lyon Sud-Est</json:string><json:string>Australia University Lyon</json:string><json:string>France CERMEP, Lyon, France Department of Cardiology, Lyon EST Hospital, Hospices Civils of Lyon, Lyon, France Department of Geriatric Medicine, Lyon Sud Hospital, Hospices Civils of Lyon, Lyon, France Department of Clinical Research, University of Bern, Bern, Switzerland Received</json:string><json:string>Lyon University Hospital, France</json:string><json:string>France CRNH RA</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>Claude Ferrand</json:string><json:string>Christophe Hautier</json:string><json:string>D. Sappey-Marinier</json:string><json:string>F. Monnet</json:string><json:string>Pr</json:string><json:string>La Doua</json:string><json:string>D. Ibarrola</json:string><json:string>E. Canet-Soulas</json:string><json:string>IRMA Biosource</json:string><json:string>Erica Chirico</json:string><json:string>Jean Capelle</json:string><json:string>A. Einstein</json:string><json:string>Chantal Simon</json:string></persName><placeName><json:string>IL</json:string><json:string>Germany</json:string><json:string>Nancy</json:string><json:string>Erlangen</json:string><json:string>Helsinki</json:string><json:string>USA</json:string><json:string>Chicago</json:string><json:string>France</json:string><json:string>Lyon</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Bergouignan et al. 2006</json:string><json:string>Lynch et al. 2007</json:string><json:string>Boon et al. 2007</json:string><json:string>Tanaka et al. 2001</json:string><json:string>Kiens 2006</json:string><json:string>van Loon et al. 2003</json:string><json:string>Matthews et al. 1985</json:string><json:string>Pruchnic et al. 2004</json:string><json:string>Zehnder et al. 2005</json:string><json:string>Boesch et al.</json:string><json:string>Lee et al. 2004</json:string><json:string>Moro et al. 2008</json:string><json:string>Ith et al. 2010</json:string><json:string>Goodpaster et al. 2001</json:string><json:string>Rosen et al. 1998</json:string><json:string>Bachmann et al. 2001</json:string><json:string>Huggett et al. 2005</json:string><json:string>Ferrand et al. 2008</json:string><json:string>Cree et al. 2004</json:string><json:string>Szczepaniak et al. 1999</json:string><json:string>Steffensen et al. 2002</json:string><json:string>Larson-Meyer et al. 2008</json:string><json:string>Schrauwen et al. 2002</json:string><json:string>Boesch et al. 1999</json:string><json:string>Tamura et al. 2008</json:string><json:string>Thamer et al. 2003</json:string><json:string>Boesch et al. 2006</json:string><json:string>Vogt et al. 2003</json:string><json:string>Ainsworth et al. 2000</json:string><json:string>Rouffet et al.</json:string><json:string>Nakagawa et al. 2007</json:string><json:string>Petersen et al. 2003</json:string><json:string>van Loon et al. 2004</json:string><json:string>Machann et al. 2011</json:string><json:string>Zehnder et al. 2006</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-DVP5MGK8-1</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - physiology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - biomedical research</json:string><json:string>3 - physiology</json:string></scienceMetrix><scopus><json:string>1 - Life Sciences</json:string><json:string>2 - Biochemistry, Genetics and Molecular Biology</json:string><json:string>3 - Physiology</json:string></scopus></categories><publicationDate>2013</publicationDate><copyrightDate>2013</copyrightDate><doi><json:string>10.1111/apha.12045</json:string></doi><id>D7228EAC54788E1C7C4519490829B4139D4F077A</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/D7228EAC54788E1C7C4519490829B4139D4F077A/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/D7228EAC54788E1C7C4519490829B4139D4F077A/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/D7228EAC54788E1C7C4519490829B4139D4F077A/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Intramyocellular lipid variations in active older men: relationship with aerobic fitness</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Publishing Ltd</publisher><availability><licence>© 2012 The Authors Acta Physiologica © 2012 Scandinavian Physiological Society</licence></availability><date type="published" when="2013-03"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Intramyocellular lipid variations in active older men: relationship with aerobic fitness</title><author xml:id="author-0000"><persName><forename type="first">D.</forename><surname>Rouffet</surname></persName><affiliation><orgName>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation><affiliation><orgName>ISEAL</orgName><orgName>Victoria University</orgName><address><settlement type="city">Melbourne</settlement><region>Vic.</region><country key="AU">Australia</country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">C.</forename><surname>Villars</surname></persName><affiliation><orgName>University Lyon 1, CRIS, EA647</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation><affiliation><orgName>CRNH RA and CENS, University Lyon 1</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">R.</forename><surname>Fissoune</surname></persName><affiliation><orgName>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">D.</forename><surname>Sappey‐Marinier</surname></persName><affiliation><orgName>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation><affiliation><orgName>CERMEP</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">M.</forename><surname>Laville</surname></persName><affiliation><orgName>CRNH RA and CENS, University Lyon 1</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation></author><author xml:id="author-0005"><persName><forename type="first">D.</forename><surname>Ibarrola</surname></persName><affiliation><orgName>CERMEP</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation></author><author xml:id="author-0006"><persName><forename type="first">M.</forename><surname>Sothier</surname></persName><affiliation><orgName>CRNH RA and CENS, University Lyon 1</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation></author><author xml:id="author-0007"><persName><forename type="first">M.‐F.</forename><surname>Monnet</surname></persName><affiliation><orgName>Department of Cardiology</orgName><orgName>Lyon EST Hospital</orgName><orgName>Hospices Civils of Lyon</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation></author><author xml:id="author-0008"><persName><forename type="first">M.</forename><surname>Ovize</surname></persName><affiliation><orgName>Department of Cardiology</orgName><orgName>Lyon EST Hospital</orgName><orgName>Hospices Civils of Lyon</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation></author><author xml:id="author-0009"><persName><forename type="first">M.</forename><surname>Bonnefoy</surname></persName><affiliation><orgName>Department of Geriatric Medicine</orgName><orgName>Lyon Sud Hospital</orgName><orgName>Hospices Civils of Lyon</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation></author><author xml:id="author-0010"><persName><forename type="first">C.</forename><surname>Boesch</surname></persName><affiliation><orgName>Department of Clinical Research</orgName><orgName>University of Bern</orgName><address><settlement type="city">Bern</settlement><country key="CH">Switzerland</country></address></affiliation></author><author xml:id="author-0011" role="corresp"><persName><forename type="first">E.</forename><surname>Canet‐Soulas</surname></persName><affiliation><orgName>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation><affiliation><orgName>CRNH RA and CENS, University Lyon 1</orgName><address><settlement type="city">Lyon</settlement><country key="FR">France</country></address></affiliation><affiliation>Correspondence: E. Canet‐Soulas, IUF, Université Lyon 1, CarMeN, U1060 INSERM, Campus La Doua, bat. IMBL, 11 avenue Jean Capelle, INSA de Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex, France. E‐mail: emmanuelle.canet@univ-lyon1.fr</affiliation></author><idno type="istex">D7228EAC54788E1C7C4519490829B4139D4F077A</idno><idno type="ark">ark:/67375/WNG-DVP5MGK8-1</idno><idno type="DOI">10.1111/apha.12045</idno><idno type="unit">APHA12045</idno><idno type="toTypesetVersion">file:APHA.APHA12045.pdf</idno></analytic><monogr><title level="j" type="main">Acta Physiologica</title><title level="j" type="alt">ACTA PHYSIOLOGICA</title><idno type="pISSN">1748-1708</idno><idno type="eISSN">1748-1716</idno><idno type="book-DOI">10.1111/(ISSN)1748-1716</idno><idno type="book-part-DOI">10.1111/apha.2013.207.issue-3</idno><idno type="product">APHA</idno><imprint><biblScope unit="vol">207</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="516">516</biblScope><biblScope unit="page" to="523">523</biblScope><biblScope unit="page-count">8</biblScope><date type="published" when="2013-03"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract style="main" xml:id="apha12045-abs-0001"><head>Abstract</head>
Aims
<p>Intramyocellular lipid (<hi rend="fc">IMCL</hi>) variations in older men are poorly explored. In young adults, <hi rend="fc">IMCL</hi> can be influenced by both diet and exercise interventions; this flexibility is related to aerobic fitness. We evaluated in active older adults the influence of maximal aerobic capacity on short‐term diet and exercise‐induced variations in <hi rend="fc">IMCL</hi> stores.</p>
Methods
<p>Intramyocellular lipids were measured by <hi rend="superscript">1</hi>H magnetic resonance spectroscopy (<hi rend="superscript">1</hi><hi rend="fc">H</hi>‐<hi rend="fc">MRS</hi>) after a 3‐day fat depletion‐replenishment diet (<hi rend="fc">IMCL<hi rend="subscript">FDR</hi></hi>) and immediately after a 2‐h exercise at 50% <hi rend="fc">VO</hi><hi rend="subscript">2</hi> max (<hi rend="fc">IMCL<hi rend="subscript">FDR</hi></hi><hi rend="subscript">_</hi><hi rend="fc"><hi rend="subscript">EX</hi></hi>). To further explore diet influence, the protocol was repeated after a high‐fat diet (<hi rend="fc">HF</hi>), with both pre‐ and post‐exercise measurements (<hi rend="fc">IMCL<hi rend="subscript">HF</hi></hi> and <hi rend="fc">IMCL<hi rend="subscript">HF</hi></hi><hi rend="subscript">_</hi><hi rend="fc"><hi rend="subscript">EX</hi></hi>).</p>
Results
<p>In active older men (69.8 ± 5.2 years), <hi rend="fc">IMCL<hi rend="subscript">FDR</hi></hi> was lowered by exercise (<hi rend="fc">IMCL<hi rend="subscript">FDR</hi></hi> = 3.45 ± 1.52 vs. <hi rend="fc">IMCL<hi rend="subscript">FDR</hi></hi><hi rend="subscript">_</hi><hi rend="fc"><hi rend="subscript">EX</hi></hi> = 2.74 ± 1.15 mmol kg<hi rend="superscript">−1</hi> wet weight, <hi rend="italic">P</hi> < 0.05), and exercise‐induced variations were correlated to the initial store (<hi rend="italic">P</hi> < 0.05, <hi rend="italic">r</hi> = −0.72). <hi rend="fc">IMCL<hi rend="subscript">FDR</hi></hi> was linked with aerobic fitness (<hi rend="italic">P</hi> < 0.05, <hi rend="italic">r</hi> = 0.76), when adjusted by fat mass. <hi rend="fc">IMCL<hi rend="subscript">HF</hi></hi> was lower than <hi rend="fc">IMCL<hi rend="subscript">FDR</hi></hi> (<hi rend="italic">P</hi> < 0.05), decreased after exercise (<hi rend="italic">P</hi> < 0.05) and varied also as a function of initial store (<hi rend="italic">P</hi> < 0.05, <hi rend="italic">r</hi> = −0.89), but without link with aerobic fitness. Finally, diet‐induced <hi rend="fc">IMCL</hi> store variations were positively linked to aerobic fitness (<hi rend="italic">P</hi> < 0.05, <hi rend="italic">r</hi> = 0.89).</p>
Conclusion
<p>Variations of the <hi rend="fc">IMCL</hi> stores in physically active older adults appear related to aerobic fitness, with similarly fast adaptation to short‐term interventions combining diet and exercise as young active adults.</p></abstract><textClass><keywords><term xml:id="apha12045-kwd-0001">exercise</term><term xml:id="apha12045-kwd-0002">lipids</term><term xml:id="apha12045-kwd-0003">magnetic resonance</term></keywords><keywords rend="articleCategory"><term>Original Article</term></keywords><keywords rend="tocHeading1"><term>EXERCISE</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/D7228EAC54788E1C7C4519490829B4139D4F077A/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component type="serialArticle" version="2.0" xml:id="apha12045" xml:lang="en"><header><publicationMeta level="product"><doi origin="wiley" registered="yes">10.1111/(ISSN)1748-1716</doi><issn type="print">1748-1708</issn><issn type="electronic">1748-1716</issn><idGroup><id type="product" value="APHA"></id></idGroup><titleGroup><title sort="ACTA PHYSIOLOGICA" type="main">Acta Physiologica</title><title type="short">Acta Physiol</title></titleGroup></publicationMeta><publicationMeta level="part" position="30"><doi origin="wiley">10.1111/apha.2013.207.issue-3</doi><copyright ownership="thirdParty">Copyright © 2013 Scandinavian Physiological Society</copyright><numberingGroup><numbering type="journalVolume" number="207">207</numbering><numbering type="journalIssue">3</numbering></numberingGroup><coverDate startDate="2013-03">March 2013</coverDate></publicationMeta><publicationMeta level="unit" position="120" status="forIssue" type="article"><doi>10.1111/apha.12045</doi><idGroup><id type="unit" value="APHA12045"></id></idGroup><countGroup><count number="8" type="pageTotal"></count></countGroup><titleGroup><title type="articleCategory">Original Article</title><title type="tocHeading1">EXERCISE</title></titleGroup><copyright ownership="thirdParty">© 2012 The Authors Acta Physiologica © 2012 Scandinavian Physiological Society</copyright><eventGroup><event date="2012-08-02" type="manuscriptReceived"></event><event date="2012-10-31" type="manuscriptRevised"></event><event date="2012-11-26" type="manuscriptAccepted"></event><event agent="SPS" date="2012-12-08" type="xmlCreated"></event><event type="publishedOnlineAccepted" date="2012-12-06"></event><event type="publishedOnlineEarlyUnpaginated" date="2012-12-27"></event><event type="publishedOnlineFinalForm" date="2013-02-06"></event><event type="firstOnline" date="2012-12-27"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-04"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.6.4 mode:FullText" date="2015-10-03"></event></eventGroup><numberingGroup><numbering type="pageFirst">516</numbering><numbering type="pageLast">523</numbering></numberingGroup><correspondenceTo><lineatedText><line>Correspondence: E. Canet‐Soulas, IUF, Université Lyon 1, CarMeN, U1060 INSERM, Campus La Doua, bat. IMBL, 11 avenue Jean Capelle, INSA de Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex, France.</line><line>E‐mail: <email>emmanuelle.canet@univ-lyon1.fr</email></line></lineatedText></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:APHA.APHA12045.pdf"></link></linkGroup></publicationMeta><contentMeta><titleGroup><title type="main">Intramyocellular lipid variations in active older men: relationship with aerobic fitness</title><title type="shortAuthors">D Rouffet <i>et al</i>.</title></titleGroup><creators><creator affiliationRef="#apha12045-aff-0001 #apha12045-aff-0002" creatorRole="author" xml:id="apha12045-cr-0001"><personName><givenNames>D.</givenNames> <familyName>Rouffet</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0003 #apha12045-aff-0004" creatorRole="author" xml:id="apha12045-cr-0002"><personName><givenNames>C.</givenNames> <familyName>Villars</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0001" creatorRole="author" xml:id="apha12045-cr-0003"><personName><givenNames>R.</givenNames> <familyName>Fissoune</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0001 #apha12045-aff-0005" creatorRole="author" xml:id="apha12045-cr-0004"><personName><givenNames>D.</givenNames> <familyName>Sappey‐Marinier</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0004" creatorRole="author" xml:id="apha12045-cr-0005"><personName><givenNames>M.</givenNames> <familyName>Laville</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0005" creatorRole="author" xml:id="apha12045-cr-0006"><personName><givenNames>D.</givenNames> <familyName>Ibarrola</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0004" creatorRole="author" xml:id="apha12045-cr-0007"><personName><givenNames>M.</givenNames> <familyName>Sothier</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0006" creatorRole="author" xml:id="apha12045-cr-0008"><personName><givenNames>M.‐F.</givenNames> <familyName>Monnet</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0006" creatorRole="author" xml:id="apha12045-cr-0009"><personName><givenNames>M.</givenNames> <familyName>Ovize</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0007" creatorRole="author" xml:id="apha12045-cr-0010"><personName><givenNames>M.</givenNames> <familyName>Bonnefoy</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0008" creatorRole="author" xml:id="apha12045-cr-0011"><personName><givenNames>C.</givenNames> <familyName>Boesch</familyName></personName></creator><creator affiliationRef="#apha12045-aff-0001 #apha12045-aff-0004" corresponding="yes" creatorRole="author" xml:id="apha12045-cr-0012"><personName><givenNames>E.</givenNames> <familyName>Canet‐Soulas</familyName></personName></creator></creators><affiliationGroup><affiliation countryCode="FR" type="organization" xml:id="apha12045-aff-0001"><orgName>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA</orgName> <address><city>Lyon</city> <country>France</country></address></affiliation> <affiliation countryCode="AU" type="organization" xml:id="apha12045-aff-0002"><orgDiv>ISEAL</orgDiv> <orgName>Victoria University</orgName> <address><city>Melbourne</city> <countryPart>Vic.</countryPart> <country>Australia</country></address></affiliation><affiliation countryCode="FR" type="organization" xml:id="apha12045-aff-0003"><orgName>University Lyon 1, CRIS, EA647</orgName> <address><city>Lyon</city> <country>France</country></address></affiliation><affiliation countryCode="FR" type="organization" xml:id="apha12045-aff-0004"><orgName>CRNH RA and CENS, University Lyon 1</orgName> <address><city>Lyon</city> <country>France</country></address></affiliation><affiliation countryCode="FR" type="organization" xml:id="apha12045-aff-0005"><orgName>CERMEP</orgName> <address><city>Lyon</city> <country>France</country></address></affiliation><affiliation countryCode="FR" type="organization" xml:id="apha12045-aff-0006"><orgDiv>Department of Cardiology</orgDiv> <orgName>Lyon EST Hospital</orgName> <orgName>Hospices Civils of Lyon</orgName> <address><city>Lyon</city> <country>France</country></address></affiliation><affiliation countryCode="FR" type="organization" xml:id="apha12045-aff-0007"><orgDiv>Department of Geriatric Medicine</orgDiv> <orgName>Lyon Sud Hospital</orgName> <orgName>Hospices Civils of Lyon</orgName> <address><city>Lyon</city> <country>France</country></address></affiliation><affiliation countryCode="CH" type="organization" xml:id="apha12045-aff-0008"><orgDiv>Department of Clinical Research</orgDiv> <orgName>University of Bern</orgName> <address><city>Bern</city> <country>Switzerland</country></address></affiliation></affiliationGroup><keywordGroup type="author"><keyword xml:id="apha12045-kwd-0001">exercise</keyword><keyword xml:id="apha12045-kwd-0002">lipids</keyword><keyword xml:id="apha12045-kwd-0003">magnetic resonance</keyword></keywordGroup><supportingInformation><supportingInfoItem><mediaResource alt="supporting" mimeType="application/msword" href="urn-x:wiley:17481708:media:apha12045:apha12045-sup-0001-FigS1"></mediaResource><caption><b>Figure S1</b>. T1‐weighted MRI (top row) showing position of measurements (green box for field homogeneity adjustment, yellow box for MRS measurement's voxel, and saturation bands in yellow) in the three directions (coronal, sagittal, axial).</caption></supportingInfoItem></supportingInformation><abstractGroup><abstract type="main" xml:id="apha12045-abs-0001"><title type="main">Abstract</title><section xml:id="apha12045-sec-0001"><title type="main">Aims</title><p>Intramyocellular lipid (<fc>IMCL</fc>) variations in older men are poorly explored. In young adults, <fc>IMCL</fc> can be influenced by both diet and exercise interventions; this flexibility is related to aerobic fitness. We evaluated in active older adults the influence of maximal aerobic capacity on short‐term diet and exercise‐induced variations in <fc>IMCL</fc> stores.</p></section><section xml:id="apha12045-sec-0002"><title type="main">Methods</title><p>Intramyocellular lipids were measured by <sup>1</sup>H magnetic resonance spectroscopy (<sup>1</sup><fc>H</fc>‐<fc>MRS</fc>) after a 3‐day fat depletion‐replenishment diet (<fc>IMCL<sub>FDR</sub></fc>) and immediately after a 2‐h exercise at 50% <fc>VO</fc><sub>2</sub> max (<fc>IMCL<sub>FDR</sub></fc><sub>_</sub><fc><sub>EX</sub></fc>). To further explore diet influence, the protocol was repeated after a high‐fat diet (<fc>HF</fc>), with both pre‐ and post‐exercise measurements (<fc>IMCL<sub>HF</sub></fc> and <fc>IMCL<sub>HF</sub></fc><sub>_</sub><fc><sub>EX</sub></fc>).</p></section><section xml:id="apha12045-sec-0003"><title type="main">Results</title><p>In active older men (69.8 ± 5.2 years), <fc>IMCL<sub>FDR</sub></fc> was lowered by exercise (<fc>IMCL<sub>FDR</sub></fc> = 3.45 ± 1.52 vs. <fc>IMCL<sub>FDR</sub></fc><sub>_</sub><fc><sub>EX</sub></fc> = 2.74 ± 1.15 mmol kg<sup>−1</sup> wet weight, <i>P</i> < 0.05), and exercise‐induced variations were correlated to the initial store (<i>P</i> < 0.05, <i>r</i> = −0.72). <fc>IMCL<sub>FDR</sub></fc> was linked with aerobic fitness (<i>P</i> < 0.05, <i>r</i> = 0.76), when adjusted by fat mass. <fc>IMCL<sub>HF</sub></fc> was lower than <fc>IMCL<sub>FDR</sub></fc> (<i>P</i> < 0.05), decreased after exercise (<i>P</i> < 0.05) and varied also as a function of initial store (<i>P</i> < 0.05, <i>r</i> = −0.89), but without link with aerobic fitness. Finally, diet‐induced <fc>IMCL</fc> store variations were positively linked to aerobic fitness (<i>P</i> < 0.05, <i>r</i> = 0.89).</p></section><section xml:id="apha12045-sec-0004"><title type="main">Conclusion</title><p>Variations of the <fc>IMCL</fc> stores in physically active older adults appear related to aerobic fitness, with similarly fast adaptation to short‐term interventions combining diet and exercise as young active adults.</p></section></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Intramyocellular lipid variations in active older men: relationship with aerobic fitness</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Intramyocellular lipid variations in active older men: relationship with aerobic fitness</title></titleInfo><name type="personal"><namePart type="given">D.</namePart><namePart type="family">Rouffet</namePart><affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</affiliation><affiliation>ISEAL, Victoria University, Vic., Melbourne, Australia</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C.</namePart><namePart type="family">Villars</namePart><affiliation>University Lyon 1, CRIS, EA647, Lyon, France</affiliation><affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R.</namePart><namePart type="family">Fissoune</namePart><affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D.</namePart><namePart type="family">Sappey‐Marinier</namePart><affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</affiliation><affiliation>CERMEP, Lyon, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Laville</namePart><affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D.</namePart><namePart type="family">Ibarrola</namePart><affiliation>CERMEP, Lyon, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Sothier</namePart><affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.‐F.</namePart><namePart type="family">Monnet</namePart><affiliation>Department of Cardiology, Lyon EST Hospital, Hospices Civils of Lyon, Lyon, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Ovize</namePart><affiliation>Department of Cardiology, Lyon EST Hospital, Hospices Civils of Lyon, Lyon, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Bonnefoy</namePart><affiliation>Department of Geriatric Medicine, Lyon Sud Hospital, Hospices Civils of Lyon, Lyon, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C.</namePart><namePart type="family">Boesch</namePart><affiliation>Department of Clinical Research, University of Bern, Bern, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E.</namePart><namePart type="family">Canet‐Soulas</namePart><affiliation>University Lyon 1, CarMeN, U1060 INSERM, INSA Lyon, INRA, Lyon, France</affiliation><affiliation>CRNH RA and CENS, University Lyon 1, Lyon, France</affiliation><affiliation>Correspondence: E. Canet‐Soulas, IUF, Université Lyon 1, CarMeN, U1060 INSERM, Campus La Doua, bat. IMBL, 11 avenue Jean Capelle, INSA de Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex, France.E‐mail:</affiliation><affiliation>E-mail: emmanuelle.canet@univ-lyon1.fr</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><dateIssued encoding="w3cdtf">2013-03</dateIssued><dateCreated encoding="w3cdtf">2012-12-08</dateCreated><dateCaptured encoding="w3cdtf">2012-08-02</dateCaptured><dateValid encoding="w3cdtf">2012-11-26</dateValid><copyrightDate encoding="w3cdtf">2013</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract>Intramyocellular lipid (IMCL) variations in older men are poorly explored. In young adults, IMCL can be influenced by both diet and exercise interventions; this flexibility is related to aerobic fitness. We evaluated in active older adults the influence of maximal aerobic capacity on short‐term diet and exercise‐induced variations in IMCL stores.</abstract><abstract>Intramyocellular lipids were measured by 1H magnetic resonance spectroscopy (1H‐MRS) after a 3‐day fat depletion‐replenishment diet (IMCLFDR) and immediately after a 2‐h exercise at 50% VO2 max (IMCLFDR_EX). To further explore diet influence, the protocol was repeated after a high‐fat diet (HF), with both pre‐ and post‐exercise measurements (IMCLHF and IMCLHF_EX).</abstract><abstract>In active older men (69.8 ± 5.2 years), IMCLFDR was lowered by exercise (IMCLFDR = 3.45 ± 1.52 vs. IMCLFDR_EX = 2.74 ± 1.15 mmol kg−1 wet weight, P < 0.05), and exercise‐induced variations were correlated to the initial store (P < 0.05, r = −0.72). IMCLFDR was linked with aerobic fitness (P < 0.05, r = 0.76), when adjusted by fat mass. IMCLHF was lower than IMCLFDR (P < 0.05), decreased after exercise (P < 0.05) and varied also as a function of initial store (P < 0.05, r = −0.89), but without link with aerobic fitness. Finally, diet‐induced IMCL store variations were positively linked to aerobic fitness (P < 0.05, r = 0.89).</abstract><abstract>Variations of the IMCL stores in physically active older adults appear related to aerobic fitness, with similarly fast adaptation to short‐term interventions combining diet and exercise as young active adults.</abstract><note type="additional physical form">Figure S1. T1‐weighted MRI (top row) showing position of measurements (green box for field homogeneity adjustment, yellow box for MRS measurement's voxel, and saturation bands in yellow) in the three directions (coronal, sagittal, axial).</note><subject><genre>keywords</genre><topic>exercise</topic><topic>lipids</topic><topic>magnetic resonance</topic></subject><relatedItem type="host"><titleInfo><title>Acta Physiologica</title></titleInfo><titleInfo type="abbreviated"><title>Acta Physiol</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Original Article</topic></subject><identifier type="ISSN">1748-1708</identifier><identifier type="eISSN">1748-1716</identifier><identifier type="DOI">10.1111/(ISSN)1748-1716</identifier><identifier type="PublisherID">APHA</identifier><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>207</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>516</start><end>523</end><total>8</total></extent></part></relatedItem><identifier type="istex">D7228EAC54788E1C7C4519490829B4139D4F077A</identifier><identifier type="ark">ark:/67375/WNG-DVP5MGK8-1</identifier><identifier type="DOI">10.1111/apha.12045</identifier><identifier type="ArticleID">APHA12045</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2013 Scandinavian Physiological Society© 2012 The Authors Acta Physiologica © 2012 Scandinavian Physiological Society</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/D7228EAC54788E1C7C4519490829B4139D4F077A/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002818 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 002818 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:D7228EAC54788E1C7C4519490829B4139D4F077A
|texte= Intramyocellular lipid variations in active older men: relationship with aerobic fitness
}}
| This area was generated with Dilib version V0.6.33. |  |