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Anxiety rating scales in Parkinson's disease: A validation study of the Hamilton anxiety rating scale, the Beck anxiety inventory, and the hospital anxiety and depression scale

Identifieur interne : 000163 ( Istex/Corpus ); précédent : 000162; suivant : 000164

Anxiety rating scales in Parkinson's disease: A validation study of the Hamilton anxiety rating scale, the Beck anxiety inventory, and the hospital anxiety and depression scale

Auteurs : Albert F. G. Leentjens ; Kathy Dujardin ; Laura Marsh ; Irene H. Richard ; Sergio E. Starkstein ; Pablo Martinez-Martin

Source :

RBID : ISTEX:08277AF9837056E4B0F595949AA5A9C168BB6F93

English descriptors

Abstract

Anxiety is a prevalent and disabling condition in Parkinson's disease (PD). The lack of anxiety rating scales validated for this population hampers research into anxiety in PD. The aim of this study is to assess the clinimetric properties of the Hamilton anxiety rating scale (HARS), the Beck anxiety inventory (BAI), and the hospital anxiety and depression scale (HADS) in PD patients.

Url:
DOI: 10.1002/mds.23184

Links to Exploration step

ISTEX:08277AF9837056E4B0F595949AA5A9C168BB6F93

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<div type="abstract">Anxiety is a prevalent and disabling condition in Parkinson's disease (PD). The lack of anxiety rating scales validated for this population hampers research into anxiety in PD. The aim of this study is to assess the clinimetric properties of the Hamilton anxiety rating scale (HARS), the Beck anxiety inventory (BAI), and the hospital anxiety and depression scale (HADS) in PD patients.</div>
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Background:
<p>Anxiety is a prevalent and disabling condition in Parkinson's disease (PD). The lack of anxiety rating scales validated for this population hampers research into anxiety in PD. The aim of this study is to assess the clinimetric properties of the Hamilton anxiety rating scale (HARS), the Beck anxiety inventory (BAI), and the hospital anxiety and depression scale (HADS) in PD patients.</p>
Design:
<p>Three hundred forty‐two PD patients underwent a standardized assessment including a structured interview for diagnostic and statistical manual diagnoses of anxiety disorders and completion of the HARS, BAI, and HADS. Inter‐rater reliability of the HARS was assessed in 60 patients; test‐retest reliability of the BAI and HADS in 213 and 217 patients, respectively.</p>
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<p>Thirty‐four percent of patients suffered from an anxiety disorder, whereas an additional 11.4% had clinically significant anxiety symptoms in the absence of a diagnosis of anxiety disorder. Acceptability, score distribution, and known groups validity over different levels of anxiety were adequate. Inter‐rater reliability for the HARS and test‐retest reliability for the BAI and HADS were good. The HARS, but not the BAI and HADS, had a satisfactory inter‐item correlation, convergent validity and factorial structure. For all scales, the positive predictive value was poor, and the negative predictive value was moderate.</p>
Conclusions:
<p>Given the adequate known groups validity of all three rating scales, each of these scales is likely to be useful in clinical practice or research for evaluation of symptom severity. Limitations in the construct validity of the anxiety scales in this study raise questions regarding suitability for their use in PD. © 2011 Movement Disorder Society</p>
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<p>Given the adequate known groups validity of all three rating scales, each of these scales is likely to be useful in clinical practice or research for evaluation of symptom severity. Limitations in the construct validity of the anxiety scales in this study raise questions regarding suitability for their use in PD. © 2011 Movement Disorder Society</p>
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<b>Relevant conflict of interest/financial disclosures:</b>
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<url href="http://www.michaeljfox.org">www.michaeljfox.org</url>
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<p>Full financial disclosures and author roles may be found in the online version of this article.</p>
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<title>Anxiety rating scales in Parkinson's disease: A validation study of the Hamilton anxiety rating scale, the Beck anxiety inventory, and the hospital anxiety and depression scale</title>
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<titleInfo type="abbreviated" lang="en">
<title>Validation of Anxiety Rating Scales in PD</title>
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<title>Anxiety rating scales in Parkinson's disease: A validation study of the Hamilton anxiety rating scale, the Beck anxiety inventory, and the hospital anxiety and depression scale</title>
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<name type="personal">
<namePart type="given">Albert F.G.</namePart>
<namePart type="family">Leentjens</namePart>
<namePart type="termsOfAddress">MD, PhD</namePart>
<affiliation>Department of Psychiatry, Maastricht University Medical Center, Maastricht, The Netherlands</affiliation>
<affiliation>E-mail: a.leentjens@np.unimaas.nl</affiliation>
<affiliation>Correspondence address: Department of Psychiatry, Maastricht University Medical Center, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
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<name type="personal">
<namePart type="given">Kathy</namePart>
<namePart type="family">Dujardin</namePart>
<namePart type="termsOfAddress">PhD</namePart>
<affiliation>Neurology and Movement Disorders Unit, Lille University Hospital, Lille, France</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
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</name>
<name type="personal">
<namePart type="given">Laura</namePart>
<namePart type="family">Marsh</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA</affiliation>
<affiliation>Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA</affiliation>
<affiliation>Current Address: Laura Marsh Mental Health Care Line, Michael E. DeBakey Veterans Administration Medical Center and Menninger Department of Psychiatry, Baylor College of Medicine, Houston, Texas, USA</affiliation>
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<roleTerm type="text">author</roleTerm>
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<name type="personal">
<namePart type="given">Irene H.</namePart>
<namePart type="family">Richard</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA</affiliation>
<affiliation>Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
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<name type="personal">
<namePart type="given">Sergio E.</namePart>
<namePart type="family">Starkstein</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>School of Psychiatry, University of Western Australia and Fremantle Hospital, Fremantle, Western Australia, Australia</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
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<name type="personal">
<namePart type="given">Pablo</namePart>
<namePart type="family">Martinez‐Martin</namePart>
<namePart type="termsOfAddress">MD, PhD</namePart>
<affiliation>Area of Applied Epidemiology and CIBERNED, National Centre for Epidemiology, Carlos III Institute of Health, Madrid, Spain</affiliation>
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<dateIssued encoding="w3cdtf">2011-02-15</dateIssued>
<dateCaptured encoding="w3cdtf">2010-01-11</dateCaptured>
<dateValid encoding="w3cdtf">2010-03-23</dateValid>
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<abstract>Anxiety is a prevalent and disabling condition in Parkinson's disease (PD). The lack of anxiety rating scales validated for this population hampers research into anxiety in PD. The aim of this study is to assess the clinimetric properties of the Hamilton anxiety rating scale (HARS), the Beck anxiety inventory (BAI), and the hospital anxiety and depression scale (HADS) in PD patients.</abstract>
<abstract>Three hundred forty‐two PD patients underwent a standardized assessment including a structured interview for diagnostic and statistical manual diagnoses of anxiety disorders and completion of the HARS, BAI, and HADS. Inter‐rater reliability of the HARS was assessed in 60 patients; test‐retest reliability of the BAI and HADS in 213 and 217 patients, respectively.</abstract>
<abstract>Thirty‐four percent of patients suffered from an anxiety disorder, whereas an additional 11.4% had clinically significant anxiety symptoms in the absence of a diagnosis of anxiety disorder. Acceptability, score distribution, and known groups validity over different levels of anxiety were adequate. Inter‐rater reliability for the HARS and test‐retest reliability for the BAI and HADS were good. The HARS, but not the BAI and HADS, had a satisfactory inter‐item correlation, convergent validity and factorial structure. For all scales, the positive predictive value was poor, and the negative predictive value was moderate.</abstract>
<abstract>Given the adequate known groups validity of all three rating scales, each of these scales is likely to be useful in clinical practice or research for evaluation of symptom severity. Limitations in the construct validity of the anxiety scales in this study raise questions regarding suitability for their use in PD. © 2011 Movement Disorder Society</abstract>
<note type="content">*Relevant conflict of interest/financial disclosures: Nothing to report. This study was sponsored by a grant from the Michael J Fox Foundation for Parkinson Research (MJFF; www.michaeljfox.org). Full financial disclosures and author roles may be found in the online version of this article.</note>
<subject lang="en">
<genre>keywords</genre>
<topic>Parkinson's disease</topic>
<topic>anxiety</topic>
<topic>depression</topic>
<topic>clinimetrics</topic>
<topic>psychometrics</topic>
<topic>rating scales</topic>
<topic>validity</topic>
<topic>reliability</topic>
</subject>
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<titleInfo>
<title>Movement Disorders</title>
</titleInfo>
<titleInfo type="abbreviated">
<title>Mov. Disord.</title>
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<genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre>
<note type="content"> Additional Supporting Information may be found in the online version of this article.Supporting Info Item: Supporting Information - Supporting Information Author Roles and Disclosures - </note>
<subject>
<genre>article-category</genre>
<topic>Research Article</topic>
</subject>
<identifier type="ISSN">0885-3185</identifier>
<identifier type="eISSN">1531-8257</identifier>
<identifier type="DOI">10.1002/(ISSN)1531-8257</identifier>
<identifier type="PublisherID">MDS</identifier>
<part>
<date>2011</date>
<detail type="volume">
<caption>vol.</caption>
<number>26</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>3</number>
</detail>
<extent unit="pages">
<start>407</start>
<end>415</end>
<total>9</total>
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<identifier type="ark">ark:/67375/WNG-747J0S49-X</identifier>
<identifier type="DOI">10.1002/mds.23184</identifier>
<identifier type="ArticleID">MDS23184</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2011 Movement Disorder Society</accessCondition>
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