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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Sleep Disordered Breathing in a High-Risk Cohort Prevalence and Severity across Pregnancy</title><author><name sortKey="Facco, Francesca L" sort="Facco, Francesca L" uniqKey="Facco F" first="Francesca L." last="Facco">Francesca L. Facco</name><affiliation><nlm:aff id="A1"> Department of Obstetrics and Gynecology, University of Pittsburgh, Magee Womens Hospital, Chicago, Illinois</nlm:aff></affiliation></author><author><name sortKey="Ouyang, David W" sort="Ouyang, David W" uniqKey="Ouyang D" first="David W." last="Ouyang">David W. Ouyang</name><affiliation><nlm:aff id="A2"> Department of Obstetrics and Gynecology, NorthShore University HealthSystem, University of Chicago, Pritzker School of Medicine, Evanston, Illinois</nlm:aff></affiliation></author><author><name sortKey="Zee, Phyllis C" sort="Zee, Phyllis C" uniqKey="Zee P" first="Phyllis C." last="Zee">Phyllis C. Zee</name><affiliation><nlm:aff id="A3"> Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois</nlm:aff></affiliation></author><author><name sortKey="Grobman, William A" sort="Grobman, William A" uniqKey="Grobman W" first="William A." last="Grobman">William A. Grobman</name><affiliation><nlm:aff id="A4"> Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24515622</idno><idno type="pmc">4531051</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531051</idno><idno type="RBID">PMC:4531051</idno><idno type="doi">10.1055/s-0033-1363768</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001559</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001559</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Sleep Disordered Breathing in a High-Risk Cohort Prevalence and Severity across Pregnancy</title><author><name sortKey="Facco, Francesca L" sort="Facco, Francesca L" uniqKey="Facco F" first="Francesca L." last="Facco">Francesca L. Facco</name><affiliation><nlm:aff id="A1"> Department of Obstetrics and Gynecology, University of Pittsburgh, Magee Womens Hospital, Chicago, Illinois</nlm:aff></affiliation></author><author><name sortKey="Ouyang, David W" sort="Ouyang, David W" uniqKey="Ouyang D" first="David W." last="Ouyang">David W. Ouyang</name><affiliation><nlm:aff id="A2"> Department of Obstetrics and Gynecology, NorthShore University HealthSystem, University of Chicago, Pritzker School of Medicine, Evanston, Illinois</nlm:aff></affiliation></author><author><name sortKey="Zee, Phyllis C" sort="Zee, Phyllis C" uniqKey="Zee P" first="Phyllis C." last="Zee">Phyllis C. Zee</name><affiliation><nlm:aff id="A3"> Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois</nlm:aff></affiliation></author><author><name sortKey="Grobman, William A" sort="Grobman, William A" uniqKey="Grobman W" first="William A." last="Grobman">William A. Grobman</name><affiliation><nlm:aff id="A4"> Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois</nlm:aff></affiliation></author></analytic><series><title level="j">American journal of perinatology</title><idno type="ISSN">0735-1631</idno><idno type="eISSN">1098-8785</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title><p id="P1">The objective of this study was to determine the prevalence and incidence of sleep disordered breathing (SDB) in pregnancy among high-risk women.</p></sec><sec id="S2"><title>Study Design</title><p id="P2">This was a prospective, observational study. We recruited women with a body mass index (BMI) 30 ≥ kg/m<sup>2</sup>, chronic hypertension, pregestational diabetes, history of preeclampsia, and/or a twin gestation. Objective assessment of SDB was completed between 6 and 20 weeks and again in the third trimester. SDB was defined as an apnea–hypopnea index (AHI) ≥ 5, and further grouped into severity categories: mild (5–14.9), moderate (15–29.9) and severe (≥30). Subjects who had a normal AHI at the baseline (AHI < 5), but an abnormal study in the third trimester (AHI 5) were classified as having “new-onset” SDB.</p></sec><sec id="S3"><title>Results</title><p id="P3">A total of 128 women were recruited. In early pregnancy 21, 6 and 3% had mild, moderate, or severe SDB, respectively. These frequencies increased to 35, 7, and 5% in the third trimester (<italic>p</italic> < 0.001). About 27% (<italic>n</italic> = 34) experienced a worsening of SDB during pregnancy; 26 were cases of new-onset SDB, while the other 8 had SDB in early pregnancy that worsened in severity. The incidence of new-onset SDB was 20%. The majority of these new-onset cases were mild.</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">SDB in early pregnancy is common in high-risk women and new-onset SDB occurs in 20% of these women.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8405212</journal-id><journal-id journal-id-type="pubmed-jr-id">1287</journal-id><journal-id journal-id-type="nlm-ta">Am J Perinatol</journal-id><journal-id journal-id-type="iso-abbrev">Am J Perinatol</journal-id><journal-title-group><journal-title>American journal of perinatology</journal-title></journal-title-group><issn pub-type="ppub">0735-1631</issn><issn pub-type="epub">1098-8785</issn></journal-meta><article-meta><article-id pub-id-type="pmid">24515622</article-id><article-id pub-id-type="pmc">4531051</article-id><article-id pub-id-type="doi">10.1055/s-0033-1363768</article-id><article-id pub-id-type="manuscript">NIHMS685137</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Sleep Disordered Breathing in a High-Risk Cohort Prevalence and Severity across Pregnancy</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Facco</surname><given-names>Francesca L.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Ouyang</surname><given-names>David W.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Zee</surname><given-names>Phyllis C.</given-names></name><degrees>MD, PhD</degrees><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Grobman</surname><given-names>William A.</given-names></name><degrees>MD, MBA</degrees><xref ref-type="aff" rid="A4">4</xref></contrib></contrib-group><aff id="A1"><label>1</label> Department of Obstetrics and Gynecology, University of Pittsburgh, Magee Womens Hospital, Chicago, Illinois</aff><aff id="A2"><label>2</label> Department of Obstetrics and Gynecology, NorthShore University HealthSystem, University of Chicago, Pritzker School of Medicine, Evanston, Illinois</aff><aff id="A3"><label>3</label> Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois</aff><aff id="A4"><label>4</label> Department of Obstetrics and Gynecology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois</aff><author-notes><corresp id="CR1"><bold>Address for correspondence</bold> Francesca Facco, MD, Department of Obstetrics and Gynecology, Magee-Womens Hospital, 300 Halket Street, Room 2233, Pittsburgh, PA 15213 (<email>faccof@upmc.edu</email>).</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>30</day><month>4</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>10</day><month>2</month><year>2014</year></pub-date><pub-date pub-type="ppub"><month>11</month><year>2014</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>11</month><year>2015</year></pub-date><volume>31</volume><issue>10</issue><fpage>899</fpage><lpage>904</lpage><pmc-comment>elocation-id from pubmed: 10.1055/s-0033-1363768</pmc-comment>
<abstract><sec id="S1"><title>Objective</title><p id="P1">The objective of this study was to determine the prevalence and incidence of sleep disordered breathing (SDB) in pregnancy among high-risk women.</p></sec><sec id="S2"><title>Study Design</title><p id="P2">This was a prospective, observational study. We recruited women with a body mass index (BMI) 30 ≥ kg/m<sup>2</sup>, chronic hypertension, pregestational diabetes, history of preeclampsia, and/or a twin gestation. Objective assessment of SDB was completed between 6 and 20 weeks and again in the third trimester. SDB was defined as an apnea–hypopnea index (AHI) ≥ 5, and further grouped into severity categories: mild (5–14.9), moderate (15–29.9) and severe (≥30). Subjects who had a normal AHI at the baseline (AHI < 5), but an abnormal study in the third trimester (AHI 5) were classified as having “new-onset” SDB.</p></sec><sec id="S3"><title>Results</title><p id="P3">A total of 128 women were recruited. In early pregnancy 21, 6 and 3% had mild, moderate, or severe SDB, respectively. These frequencies increased to 35, 7, and 5% in the third trimester (<italic>p</italic> < 0.001). About 27% (<italic>n</italic> = 34) experienced a worsening of SDB during pregnancy; 26 were cases of new-onset SDB, while the other 8 had SDB in early pregnancy that worsened in severity. The incidence of new-onset SDB was 20%. The majority of these new-onset cases were mild.</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">SDB in early pregnancy is common in high-risk women and new-onset SDB occurs in 20% of these women.</p></sec></abstract><kwd-group><kwd>sleep disordered breathing</kwd><kwd>sleep apnea</kwd><kwd>pregnancy</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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