Ophthalmic Manifestations of HIV Patients in a Rural Area of Western Maharashtra, India
Identifieur interne : 004A34 ( Ncbi/Curation ); précédent : 004A33; suivant : 004A35Ophthalmic Manifestations of HIV Patients in a Rural Area of Western Maharashtra, India
Auteurs : Pratik Y. Gogri [Inde] ; Somen L. Misra [Inde] ; Raghunandan N. Kothari [Inde] ; Akshay J. Bhandari [Inde] ; Hitesh V. Gidwani [États-Unis]Source :
- International Scholarly Research Notices [ 2356-7872 ] ; 2014.
Abstract
Url:
DOI: 10.1155/2014/347638
PubMed: 27355047
PubMed Central: 4897481
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Gogri</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Ophthalmology, Rural Medical College and Pravara Rural Hospital of Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra 413736, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Ophthalmology, Rural Medical College and Pravara Rural Hospital of Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra 413736</wicri:regionArea><wicri:noRegion>Maharashtra 413736</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I2">Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736</wicri:regionArea><wicri:noRegion>Maharashtra 413736</wicri:noRegion></affiliation></author><author><name sortKey="Misra, Somen L" sort="Misra, Somen L" uniqKey="Misra S" first="Somen L." last="Misra">Somen L. Misra</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736</wicri:regionArea><wicri:noRegion>Maharashtra 413736</wicri:noRegion></affiliation></author><author><name sortKey="Kothari, Raghunandan N" sort="Kothari, Raghunandan N" uniqKey="Kothari R" first="Raghunandan N." last="Kothari">Raghunandan N. Kothari</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Ophthalmology, Smt. B. K. Shah Medical Institute & Research Centre, Vadodara, Gujarat 391750, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Ophthalmology, Smt. B. K. 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Gidwani</name><affiliation wicri:level="2"><nlm:aff id="I4">Department of Medicine, UPMC Mercy, Pittsburgh, PA 15219, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, UPMC Mercy, Pittsburgh, PA 15219</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27355047</idno><idno type="pmc">4897481</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897481</idno><idno type="RBID">PMC:4897481</idno><idno type="doi">10.1155/2014/347638</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001B67</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001B67</idno><idno type="wicri:Area/Pmc/Curation">001B42</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001B42</idno><idno type="wicri:Area/Pmc/Checkpoint">000B19</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000B19</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">001527</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001527</idno><idno type="wicri:Area/PubMed/Curation">001521</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001521</idno><idno type="wicri:Area/PubMed/Checkpoint">001521</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001521</idno><idno type="wicri:Area/Ncbi/Merge">004A34</idno><idno type="wicri:Area/Ncbi/Curation">004A34</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Ophthalmic Manifestations of HIV Patients in a Rural Area of Western Maharashtra, India</title><author><name sortKey="Gogri, Pratik Y" sort="Gogri, Pratik Y" uniqKey="Gogri P" first="Pratik Y." last="Gogri">Pratik Y. Gogri</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Ophthalmology, Rural Medical College and Pravara Rural Hospital of Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra 413736, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Ophthalmology, Rural Medical College and Pravara Rural Hospital of Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra 413736</wicri:regionArea><wicri:noRegion>Maharashtra 413736</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I2">Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736</wicri:regionArea><wicri:noRegion>Maharashtra 413736</wicri:noRegion></affiliation></author><author><name sortKey="Misra, Somen L" sort="Misra, Somen L" uniqKey="Misra S" first="Somen L." last="Misra">Somen L. Misra</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736</wicri:regionArea><wicri:noRegion>Maharashtra 413736</wicri:noRegion></affiliation></author><author><name sortKey="Kothari, Raghunandan N" sort="Kothari, Raghunandan N" uniqKey="Kothari R" first="Raghunandan N." last="Kothari">Raghunandan N. Kothari</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Ophthalmology, Smt. B. K. Shah Medical Institute & Research Centre, Vadodara, Gujarat 391750, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Ophthalmology, Smt. B. K. Shah Medical Institute & Research Centre, Vadodara, Gujarat 391750</wicri:regionArea><wicri:noRegion>Gujarat 391750</wicri:noRegion></affiliation></author><author><name sortKey="Bhandari, Akshay J" sort="Bhandari, Akshay J" uniqKey="Bhandari A" first="Akshay J." last="Bhandari">Akshay J. Bhandari</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736, India</nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Ophthalmology, Pravara Institute of Medical Sciences, Loni, Maharashtra 413736</wicri:regionArea><wicri:noRegion>Maharashtra 413736</wicri:noRegion></affiliation></author><author><name sortKey="Gidwani, Hitesh V" sort="Gidwani, Hitesh V" uniqKey="Gidwani H" first="Hitesh V." last="Gidwani">Hitesh V. Gidwani</name><affiliation wicri:level="2"><nlm:aff id="I4">Department of Medicine, UPMC Mercy, Pittsburgh, PA 15219, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, UPMC Mercy, Pittsburgh, PA 15219</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author></analytic><series><title level="j">International Scholarly Research Notices</title><idno type="eISSN">2356-7872</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><italic>Introduction.</italic> HIV/AIDS is one of twenty first century's biggest global challenges to mankind with protean manifestations affecting all organs of our body, not even sparing the eyes. The purpose of this study was to determine the pattern of ocular manifestations of HIV/AIDS and their correlation with CD4-count in a rural area of India. <italic>Methods.</italic> A hospital based observational cross-sectional study was done on 40 HIV-positive patients presenting to ART center with ocular complaints. Data were collected using face-to-face interview, clinical examination, slit lamp examination, fundus examination, and laboratory investigations. <italic>Results.</italic> Out of 40 patients, 21 were males and 19 were females with mean age of 38.75 ± 13.9 years. HIV retinopathy was the most common HIV-associated ophthalmic lesion while anterior uveitis was the most common anterior segment finding. Posterior segment lesions showed significant association (<italic>P</italic> < 0.05) with low CD4-count of the patient. CMV retinitis, retinal detachment, tubercular chorioretinitis, and acute retinal necrosis were all seen in patients with CD4-count less than 100 cells/mm<sup>3</sup>. <italic>Conclusions.</italic> HIV retinopathy, CMV retinitis, herpes zoster ophthalmicus, and anterior uveitis are common ocular manifestations associated with HIV infection. Low CD4-count is a risk as well as predictor for ocular manifestations. There needs to be awareness of ocular involvement among HIV infected individuals and an increased emphasis on regular ophthalmic examination.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Fauci, A S" uniqKey="Fauci A">A. S. Fauci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hodge, W G" uniqKey="Hodge W">W. G. Hodge</name></author><author><name sortKey="Seiff, S R" uniqKey="Seiff S">S. R. Seiff</name></author><author><name sortKey="Margolis, T P" uniqKey="Margolis T">T. P. 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