Regional amyloid burden and intrinsic connectivity networks in cognitively normal elderly subjects
Identifieur interne : 003793 ( Ncbi/Checkpoint ); précédent : 003792; suivant : 003794Regional amyloid burden and intrinsic connectivity networks in cognitively normal elderly subjects
Auteurs : Hyun Kook Lim [Corée du Sud, États-Unis] ; Robert Nebes [États-Unis] ; Beth Snitz [États-Unis] ; Ann Cohen [États-Unis] ; Chester Mathis [États-Unis] ; Julie Price [États-Unis] ; Lisa Weissfeld [États-Unis] ; William Klunk [États-Unis] ; Howard J. Aizenstein [États-Unis]Source :
- Brain [ 0006-8950 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Amyloïde (métabolisme), Cartographie cérébrale (), Encéphale (anatomopathologie), Encéphale (métabolisme), Femelle, Humains, Imagerie par résonance magnétique (), Maladie d'Alzheimer (anatomopathologie), Maladie d'Alzheimer (métabolisme), Mâle, Réseau nerveux (physiopathologie), Sujet âgé, Sujet âgé de 80 ans ou plus, Tests neuropsychologiques, Traitement d'image par ordinateur.
- MESH :
- anatomopathologie : Encéphale, Maladie d'Alzheimer.
- métabolisme : Amyloïde, Encéphale, Maladie d'Alzheimer.
- physiopathologie : Réseau nerveux.
- Adulte d'âge moyen, Cartographie cérébrale, Femelle, Humains, Imagerie par résonance magnétique, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Tests neuropsychologiques, Traitement d'image par ordinateur.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Alzheimer Disease (metabolism), Alzheimer Disease (pathology), Amyloid (metabolism), Brain (metabolism), Brain (pathology), Brain Mapping (methods), Female, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging (methods), Male, Middle Aged, Nerve Net (physiopathology), Neuropsychological Tests.
- MESH :
- chemical , metabolism : Amyloid.
- metabolism : Alzheimer Disease, Brain.
- methods : Brain Mapping, Magnetic Resonance Imaging.
- pathology : Alzheimer Disease, Brain.
- physiopathology : Nerve Net.
- Aged, Aged, 80 and over, Female, Humans, Image Processing, Computer-Assisted, Male, Middle Aged, Neuropsychological Tests.
Abstract
See Toga and Thompson (doi:
Hyun Kook Lim
Url:
DOI: 10.1093/brain/awu271
PubMed: 25266592
PubMed Central: 4240287
Affiliations:
- Corée du Sud, États-Unis
- Pennsylvanie, Région capitale de Séoul
- Pittsburgh, Séoul
- Université de Pittsburgh
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PMC:4240287Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Alzheimer Disease (metabolism)</term>
<term>Alzheimer Disease (pathology)</term>
<term>Amyloid (metabolism)</term>
<term>Brain (metabolism)</term>
<term>Brain (pathology)</term>
<term>Brain Mapping (methods)</term>
<term>Female</term>
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<term>Image Processing, Computer-Assisted</term>
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<term>Middle Aged</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Amyloïde (métabolisme)</term>
<term>Cartographie cérébrale ()</term>
<term>Encéphale (anatomopathologie)</term>
<term>Encéphale (métabolisme)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Imagerie par résonance magnétique ()</term>
<term>Maladie d'Alzheimer (anatomopathologie)</term>
<term>Maladie d'Alzheimer (métabolisme)</term>
<term>Mâle</term>
<term>Réseau nerveux (physiopathologie)</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tests neuropsychologiques</term>
<term>Traitement d'image par ordinateur</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Amyloid</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Encéphale</term>
<term>Maladie d'Alzheimer</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Alzheimer Disease</term>
<term>Brain</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Brain Mapping</term>
<term>Magnetic Resonance Imaging</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Amyloïde</term>
<term>Encéphale</term>
<term>Maladie d'Alzheimer</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Alzheimer Disease</term>
<term>Brain</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Réseau nerveux</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Nerve Net</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Image Processing, Computer-Assisted</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Cartographie cérébrale</term>
<term>Femelle</term>
<term>Humains</term>
<term>Imagerie par résonance magnétique</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tests neuropsychologiques</term>
<term>Traitement d'image par ordinateur</term>
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<front><div type="abstract" xml:lang="en"><p>See Toga and Thompson (doi:<related-article id="d35e190" related-article-type="companion" ext-link-type="doi" xlink:href="10.1093/brain/awu276">10.1093/brain/awu276</related-article>
) for a scientific commentary on this article.</p>
<p>Hyun Kook Lim <italic>et al.</italic>
investigate the relationship between amyloid burden and intrinsic functional connectivity in cognitively normal older adults. Individuals with amyloid deposition show aberrant functional connectivity in the default mode and central executive networks compared to those without detectable amyloid. Changes may reflect early deleterious effects of amyloid deposition.</p>
</div>
</front>
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<name sortKey="Aizenstein, Howard J" sort="Aizenstein, Howard J" uniqKey="Aizenstein H" first="Howard J." last="Aizenstein">Howard J. Aizenstein</name>
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<name sortKey="Klunk, William" sort="Klunk, William" uniqKey="Klunk W" first="William" last="Klunk">William Klunk</name>
<name sortKey="Klunk, William" sort="Klunk, William" uniqKey="Klunk W" first="William" last="Klunk">William Klunk</name>
<name sortKey="Mathis, Chester" sort="Mathis, Chester" uniqKey="Mathis C" first="Chester" last="Mathis">Chester Mathis</name>
<name sortKey="Nebes, Robert" sort="Nebes, Robert" uniqKey="Nebes R" first="Robert" last="Nebes">Robert Nebes</name>
<name sortKey="Price, Julie" sort="Price, Julie" uniqKey="Price J" first="Julie" last="Price">Julie Price</name>
<name sortKey="Snitz, Beth" sort="Snitz, Beth" uniqKey="Snitz B" first="Beth" last="Snitz">Beth Snitz</name>
<name sortKey="Weissfeld, Lisa" sort="Weissfeld, Lisa" uniqKey="Weissfeld L" first="Lisa" last="Weissfeld">Lisa Weissfeld</name>
</country>
</tree>
</affiliations>
</record>
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