Occupational lead exposure and blood pressure.
Identifieur interne : 003863 ( Istex/Curation ); précédent : 003862; suivant : 003864Occupational lead exposure and blood pressure.
Auteurs : D K Parkinson [États-Unis] ; M J Hodgson [États-Unis] ; E J Bromet [États-Unis] ; M A Dew [États-Unis] ; M M Connell [États-Unis]Source :
- British Journal of Industrial Medicine [ 0007-1072 ] ; 1987-11.
Descripteurs français
- Wicri :
- topic : Sécurité du travail.
English descriptors
- KwdEn :
- Alcohol consumption, Antihypertensive medication, Arch environ health, Battery plants, Beta, Blood pressure, Body mass index, Cerebrovascular disease, Cerebrovascular mortality, Community studies, Comparison workers, Control beta, Control plant, Control workers, Current blood, Diastolic, Diastolic blood pressure, Education income cigarette, Excess mortality, Exercise body mass exposure, Exposure controllingfor, Exposure variables, Hypertension, National institute, Natural logarith scale, Nonexposed workers, Occupational safety, Occupational studies, Older workers, Order correlations, Pirkle etal, Predictor, Present analysis, Present study, Recent blood, Regression coefficients, Renal, Renal disease, Renal function, Risk factors, Salt deprivation, Significant effects, Smelter workers, Standardised regression coefficients exposure variables, Systolic, Systolic blood pressure, Tzinc protoporphyrins, Zinc protophorphyrinst beta.
- Teeft :
- Alcohol consumption, Antihypertensive medication, Arch environ health, Battery plants, Beta, Blood pressure, Body mass index, Cerebrovascular disease, Cerebrovascular mortality, Community studies, Comparison workers, Control beta, Control plant, Control workers, Current blood, Diastolic, Diastolic blood pressure, Education income cigarette, Excess mortality, Exercise body mass exposure, Exposure controllingfor, Exposure variables, Hypertension, National institute, Natural logarith scale, Nonexposed workers, Occupational safety, Occupational studies, Older workers, Order correlations, Pirkle etal, Predictor, Present analysis, Present study, Recent blood, Regression coefficients, Renal, Renal disease, Renal function, Risk factors, Salt deprivation, Significant effects, Smelter workers, Standardised regression coefficients exposure variables, Systolic, Systolic blood pressure, Tzinc protoporphyrins, Zinc protophorphyrinst beta.
Abstract
Recent community studies have suggested that low level lead exposure is significantly associated with blood pressure in the general population. This finding is inconsistent with the results of recent occupational studies of lead exposed workers, although the occupational studies contained serious methodological weaknesses. The present study examined the relation between occupational lead exposure and diastolic and systolic blood pressure in randomly selected samples of 270 exposed and 158 non-exposed workers. Four exposure indicators were examined: employment at a lead battery plant nu a control plant, current blood lead value, current zinc protoporphyrin value, and time weighted average blood lead value. After controlling for other known risk factors such as age, education, income, cigarette usage, alcohol consumption, and exercise, the associations between exposure and blood pressure were small and non-significant. In the absence of a biologically feasible hypothesis regarding the mechanism by which low level lead exposure would influence blood pressure the present findings challenge the validity of the general population association.
Url:
DOI: 10.1136/oem.44.11.744
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<term>Body mass index</term>
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<term>Cerebrovascular mortality</term>
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<term>Comparison workers</term>
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<term>Natural logarith scale</term>
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<term>Regression coefficients</term>
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<front><div type="abstract" xml:lang="en">Recent community studies have suggested that low level lead exposure is significantly associated with blood pressure in the general population. This finding is inconsistent with the results of recent occupational studies of lead exposed workers, although the occupational studies contained serious methodological weaknesses. The present study examined the relation between occupational lead exposure and diastolic and systolic blood pressure in randomly selected samples of 270 exposed and 158 non-exposed workers. Four exposure indicators were examined: employment at a lead battery plant nu a control plant, current blood lead value, current zinc protoporphyrin value, and time weighted average blood lead value. After controlling for other known risk factors such as age, education, income, cigarette usage, alcohol consumption, and exercise, the associations between exposure and blood pressure were small and non-significant. In the absence of a biologically feasible hypothesis regarding the mechanism by which low level lead exposure would influence blood pressure the present findings challenge the validity of the general population association.</div>
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