Comparative outcomes among the problem areas of interpersonal psychotherapy for depression
Identifieur interne : 002E36 ( Istex/Corpus ); précédent : 002E35; suivant : 002E37Comparative outcomes among the problem areas of interpersonal psychotherapy for depression
Auteurs : J. C. Levenson ; E. Frank ; Y. Cheng ; P. Rucci ; C. A. Janney ; P. Houck ; R. N. Forgione ; H. A. Swartz ; J. M. Cyranowski ; A. FagioliniSource :
- Depression and Anxiety [ 1091-4269 ] ; 2010-05.
English descriptors
- KwdEn :
- Acute phase, Adjunctive pharmacotherapy, Baseline score, Basic books, Bristol myers squibb, Careful medication management, Clinical characteristics, Clinical interview, Clinical variables, Combination therapy, Conventional levels, Depressed patients, Depression onset, Depressive, Education level, Equal success, First depressive episode, Forest research institute, Grief deficits disputes, Grief group, Guilford press, Interpersonal, Interpersonal deficits, Interpersonal deficits group, Interpersonal problems, Interpersonal psychotherapy, Life event, Maintenance therapies, Median time, Medication, More personality pathology, National institute, Other groups, Other party, Oxford university press, Patient characteristics, Personality disorder diagnosis, Personality disorders, Personality pathology, Pharmacotherapy, Problem area, Problem area assignment, Problem area group, Problem area groups, Problem areas, Proportional hazard model, Psychiatry, Psychotherapy, Rank test, Recurrent depression, Reference group, Relative efficacy, Remission, Research article, Research program, Role disputes, Role disputes group, Role transitions, Role transitions group, Role transitions groups, Secondary focus, Secondary problem area, Shorter time, Significant difference, Significant differences, Statistical significance, Study participants, Study procedures, Survival analyses, Survival times, Treatment focus, Treatment outcome, Triage points.
- Teeft :
- Acute phase, Adjunctive pharmacotherapy, Baseline score, Basic books, Bristol myers squibb, Careful medication management, Clinical characteristics, Clinical interview, Clinical variables, Combination therapy, Conventional levels, Depressed patients, Depression onset, Depressive, Education level, Equal success, First depressive episode, Forest research institute, Grief deficits disputes, Grief group, Guilford press, Interpersonal, Interpersonal deficits, Interpersonal deficits group, Interpersonal problems, Interpersonal psychotherapy, Life event, Maintenance therapies, Median time, Medication, More personality pathology, National institute, Other groups, Other party, Oxford university press, Patient characteristics, Personality disorder diagnosis, Personality disorders, Personality pathology, Pharmacotherapy, Problem area, Problem area assignment, Problem area group, Problem area groups, Problem areas, Proportional hazard model, Psychiatry, Psychotherapy, Rank test, Recurrent depression, Reference group, Relative efficacy, Remission, Research article, Research program, Role disputes, Role disputes group, Role transitions, Role transitions group, Role transitions groups, Secondary focus, Secondary problem area, Shorter time, Significant difference, Significant differences, Statistical significance, Study participants, Study procedures, Survival analyses, Survival times, Treatment focus, Treatment outcome, Triage points.
Abstract
Background: Although interpersonal psychotherapy (IPT) is an efficacious treatment for acute depression, the relative efficacy of treatment in each of the four IPT problem areas (grief, role transitions, role disputes, interpersonal deficits) has received little attention. We evaluated the specificity of IPT by comparing treatment success among patients whose psychotherapy focused on each problem area. Moreover, we sought to understand how the patient characteristics and interpersonal problems most closely linked to the onset of a patient's current depression contributed to IPT success. Methods: Patients meeting DSM‐IV criteria for an episode of major depressive disorder (n=182) were treated with weekly IPT. Remission was defined as an average Hamilton Rating Scale for Depression 17‐item score of 7 or below over 3 weeks. Personality disorders were diagnosed using the Structured Clinical Interview for DSM‐IV Personality Disorders. Results: Contrary to our prediction that patients whose treatment was focused on interpersonal deficits would take longer to remit, survival analyses indicated that patients receiving treatment focused on each of the four problem areas did not differ in their times to remission. Nor were patients in the interpersonal deficits group more likely to have an Axis II diagnosis. Patients whose treatment focused on role transitions remitted faster than those whose treatment focused on role disputes, after controlling for covariates. Conclusion: With skillful use of IPT strategies and tactics and with careful medication management where appropriate, patients in this study whose treatment focused on each problem area were treated with equal success by trained IPT clinicians. Depression and Anxiety, 2010. © 2010 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/da.20661
Links to Exploration step
ISTEX:C36DA6A36C2158534DBF665294024E4663E4D7F0Le document en format XML
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Frank</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: franke@upmc.edu</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213</mods:affiliation></affiliation></author><author><name sortKey="Cheng, Y" sort="Cheng, Y" uniqKey="Cheng Y" first="Y." last="Cheng">Y. Cheng</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Rucci, P" sort="Rucci, P" uniqKey="Rucci P" first="P." last="Rucci">P. Rucci</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Janney, C A" sort="Janney, C A" uniqKey="Janney C" first="C. A." last="Janney">C. A. Janney</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Houck, P" sort="Houck, P" uniqKey="Houck P" first="P." last="Houck">P. Houck</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Forgione, R N" sort="Forgione, R N" uniqKey="Forgione R" first="R. N." last="Forgione">R. N. Forgione</name><affiliation><mods:affiliation>Department of Psychiatry, University of Siena, Siena, Italy</mods:affiliation></affiliation></author><author><name sortKey="Swartz, H A" sort="Swartz, H A" uniqKey="Swartz H" first="H. A." last="Swartz">H. A. Swartz</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Cyranowski, J M" sort="Cyranowski, J M" uniqKey="Cyranowski J" first="J. M." last="Cyranowski">J. M. Cyranowski</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Fagiolini, A" sort="Fagiolini, A" uniqKey="Fagiolini A" first="A." last="Fagiolini">A. 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Levenson</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Frank, E" sort="Frank, E" uniqKey="Frank E" first="E." last="Frank">E. Frank</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: franke@upmc.edu</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213</mods:affiliation></affiliation></author><author><name sortKey="Cheng, Y" sort="Cheng, Y" uniqKey="Cheng Y" first="Y." last="Cheng">Y. Cheng</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Rucci, P" sort="Rucci, P" uniqKey="Rucci P" first="P." last="Rucci">P. Rucci</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Janney, C A" sort="Janney, C A" uniqKey="Janney C" first="C. A." last="Janney">C. A. Janney</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Houck, P" sort="Houck, P" uniqKey="Houck P" first="P." last="Houck">P. Houck</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Forgione, R N" sort="Forgione, R N" uniqKey="Forgione R" first="R. N." last="Forgione">R. N. Forgione</name><affiliation><mods:affiliation>Department of Psychiatry, University of Siena, Siena, Italy</mods:affiliation></affiliation></author><author><name sortKey="Swartz, H A" sort="Swartz, H A" uniqKey="Swartz H" first="H. A." last="Swartz">H. A. Swartz</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Cyranowski, J M" sort="Cyranowski, J M" uniqKey="Cyranowski J" first="J. M." last="Cyranowski">J. M. Cyranowski</name><affiliation><mods:affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</mods:affiliation></affiliation></author><author><name sortKey="Fagiolini, A" sort="Fagiolini, A" uniqKey="Fagiolini A" first="A." last="Fagiolini">A. Fagiolini</name><affiliation><mods:affiliation>Department of Neuroscience, University of Siena School of Medicine, Siena, Italy</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Depression and Anxiety</title><title level="j" type="alt">DEPRESSION AND ANXIETY</title><idno type="ISSN">1091-4269</idno><idno type="eISSN">1520-6394</idno><imprint><biblScope unit="vol">27</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="434">434</biblScope><biblScope unit="page" to="440">440</biblScope><biblScope unit="page-count">7</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-05">2010-05</date></imprint><idno type="ISSN">1091-4269</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1091-4269</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute phase</term><term>Adjunctive pharmacotherapy</term><term>Baseline score</term><term>Basic books</term><term>Bristol myers squibb</term><term>Careful medication management</term><term>Clinical characteristics</term><term>Clinical interview</term><term>Clinical variables</term><term>Combination therapy</term><term>Conventional levels</term><term>Depressed patients</term><term>Depression onset</term><term>Depressive</term><term>Education level</term><term>Equal success</term><term>First depressive episode</term><term>Forest research institute</term><term>Grief deficits disputes</term><term>Grief group</term><term>Guilford press</term><term>Interpersonal</term><term>Interpersonal deficits</term><term>Interpersonal deficits group</term><term>Interpersonal problems</term><term>Interpersonal psychotherapy</term><term>Life event</term><term>Maintenance therapies</term><term>Median time</term><term>Medication</term><term>More personality pathology</term><term>National institute</term><term>Other groups</term><term>Other party</term><term>Oxford university press</term><term>Patient characteristics</term><term>Personality disorder diagnosis</term><term>Personality disorders</term><term>Personality pathology</term><term>Pharmacotherapy</term><term>Problem area</term><term>Problem area assignment</term><term>Problem area group</term><term>Problem area groups</term><term>Problem areas</term><term>Proportional hazard model</term><term>Psychiatry</term><term>Psychotherapy</term><term>Rank test</term><term>Recurrent depression</term><term>Reference group</term><term>Relative efficacy</term><term>Remission</term><term>Research article</term><term>Research program</term><term>Role disputes</term><term>Role disputes group</term><term>Role transitions</term><term>Role transitions group</term><term>Role transitions groups</term><term>Secondary focus</term><term>Secondary problem area</term><term>Shorter time</term><term>Significant difference</term><term>Significant differences</term><term>Statistical significance</term><term>Study participants</term><term>Study procedures</term><term>Survival analyses</term><term>Survival times</term><term>Treatment focus</term><term>Treatment outcome</term><term>Triage points</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Acute phase</term><term>Adjunctive pharmacotherapy</term><term>Baseline score</term><term>Basic books</term><term>Bristol myers squibb</term><term>Careful medication management</term><term>Clinical characteristics</term><term>Clinical interview</term><term>Clinical variables</term><term>Combination therapy</term><term>Conventional levels</term><term>Depressed patients</term><term>Depression onset</term><term>Depressive</term><term>Education level</term><term>Equal success</term><term>First depressive episode</term><term>Forest research institute</term><term>Grief deficits disputes</term><term>Grief group</term><term>Guilford press</term><term>Interpersonal</term><term>Interpersonal deficits</term><term>Interpersonal deficits group</term><term>Interpersonal problems</term><term>Interpersonal psychotherapy</term><term>Life event</term><term>Maintenance therapies</term><term>Median time</term><term>Medication</term><term>More personality pathology</term><term>National institute</term><term>Other groups</term><term>Other party</term><term>Oxford university press</term><term>Patient characteristics</term><term>Personality disorder diagnosis</term><term>Personality disorders</term><term>Personality pathology</term><term>Pharmacotherapy</term><term>Problem area</term><term>Problem area assignment</term><term>Problem area group</term><term>Problem area groups</term><term>Problem areas</term><term>Proportional hazard model</term><term>Psychiatry</term><term>Psychotherapy</term><term>Rank test</term><term>Recurrent depression</term><term>Reference group</term><term>Relative efficacy</term><term>Remission</term><term>Research article</term><term>Research program</term><term>Role disputes</term><term>Role disputes group</term><term>Role transitions</term><term>Role transitions group</term><term>Role transitions groups</term><term>Secondary focus</term><term>Secondary problem area</term><term>Shorter time</term><term>Significant difference</term><term>Significant differences</term><term>Statistical significance</term><term>Study participants</term><term>Study procedures</term><term>Survival analyses</term><term>Survival times</term><term>Treatment focus</term><term>Treatment outcome</term><term>Triage points</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Although interpersonal psychotherapy (IPT) is an efficacious treatment for acute depression, the relative efficacy of treatment in each of the four IPT problem areas (grief, role transitions, role disputes, interpersonal deficits) has received little attention. We evaluated the specificity of IPT by comparing treatment success among patients whose psychotherapy focused on each problem area. Moreover, we sought to understand how the patient characteristics and interpersonal problems most closely linked to the onset of a patient's current depression contributed to IPT success. Methods: Patients meeting DSM‐IV criteria for an episode of major depressive disorder (n=182) were treated with weekly IPT. Remission was defined as an average Hamilton Rating Scale for Depression 17‐item score of 7 or below over 3 weeks. Personality disorders were diagnosed using the Structured Clinical Interview for DSM‐IV Personality Disorders. Results: Contrary to our prediction that patients whose treatment was focused on interpersonal deficits would take longer to remit, survival analyses indicated that patients receiving treatment focused on each of the four problem areas did not differ in their times to remission. Nor were patients in the interpersonal deficits group more likely to have an Axis II diagnosis. Patients whose treatment focused on role transitions remitted faster than those whose treatment focused on role disputes, after controlling for covariates. Conclusion: With skillful use of IPT strategies and tactics and with careful medication management where appropriate, patients in this study whose treatment focused on each problem area were treated with equal success by trained IPT clinicians. Depression and Anxiety, 2010. © 2010 Wiley‐Liss, Inc.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>remission</json:string><json:string>interpersonal psychotherapy</json:string><json:string>interpersonal deficits</json:string><json:string>problem areas</json:string><json:string>problem area</json:string><json:string>depressive</json:string><json:string>role transitions</json:string><json:string>interpersonal deficits group</json:string><json:string>role disputes</json:string><json:string>pharmacotherapy</json:string><json:string>role transitions group</json:string><json:string>role disputes group</json:string><json:string>interpersonal</json:string><json:string>problem area groups</json:string><json:string>personality disorders</json:string><json:string>proportional hazard model</json:string><json:string>depression onset</json:string><json:string>shorter time</json:string><json:string>personality pathology</json:string><json:string>reference group</json:string><json:string>study participants</json:string><json:string>bristol myers squibb</json:string><json:string>treatment focus</json:string><json:string>treatment outcome</json:string><json:string>research article</json:string><json:string>clinical variables</json:string><json:string>secondary problem area</json:string><json:string>depressed patients</json:string><json:string>secondary focus</json:string><json:string>problem area assignment</json:string><json:string>grief group</json:string><json:string>clinical interview</json:string><json:string>median time</json:string><json:string>first depressive episode</json:string><json:string>medication</json:string><json:string>careful medication management</json:string><json:string>equal success</json:string><json:string>acute phase</json:string><json:string>maintenance therapies</json:string><json:string>triage points</json:string><json:string>baseline score</json:string><json:string>adjunctive pharmacotherapy</json:string><json:string>relative efficacy</json:string><json:string>forest research institute</json:string><json:string>guilford press</json:string><json:string>national institute</json:string><json:string>recurrent depression</json:string><json:string>clinical characteristics</json:string><json:string>education level</json:string><json:string>patient characteristics</json:string><json:string>survival analyses</json:string><json:string>role transitions groups</json:string><json:string>problem area group</json:string><json:string>interpersonal problems</json:string><json:string>oxford university press</json:string><json:string>conventional levels</json:string><json:string>statistical significance</json:string><json:string>survival times</json:string><json:string>life event</json:string><json:string>other party</json:string><json:string>rank test</json:string><json:string>more personality pathology</json:string><json:string>personality disorder diagnosis</json:string><json:string>significant differences</json:string><json:string>combination therapy</json:string><json:string>grief deficits disputes</json:string><json:string>other groups</json:string><json:string>significant difference</json:string><json:string>basic books</json:string><json:string>research program</json:string><json:string>study procedures</json:string><json:string>psychiatry</json:string><json:string>psychotherapy</json:string></teeft></keywords><author><json:item><name>J.C. Levenson M.S.</name><affiliations><json:string>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</json:string><json:string>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania</json:string></affiliations></json:item><json:item><name>E. Frank Ph.D.</name><affiliations><json:string>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</json:string><json:string>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania</json:string><json:string>E-mail: franke@upmc.edu</json:string><json:string>Correspondence address: Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213</json:string></affiliations></json:item><json:item><name>Y. Cheng Ph.D.</name><affiliations><json:string>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</json:string><json:string>Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania</json:string></affiliations></json:item><json:item><name>P. Rucci Ph.D.</name><affiliations><json:string>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</json:string></affiliations></json:item><json:item><name>C.A. Janney M.S.</name><affiliations><json:string>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</json:string><json:string>Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania</json:string></affiliations></json:item><json:item><name>P. Houck M.S.</name><affiliations><json:string>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</json:string></affiliations></json:item><json:item><name>R.N. Forgione D.Econ.</name><affiliations><json:string>Department of Psychiatry, University of Siena, Siena, Italy</json:string></affiliations></json:item><json:item><name>H.A. Swartz M.D.</name><affiliations><json:string>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</json:string></affiliations></json:item><json:item><name>J.M. Cyranowski Ph.D.</name><affiliations><json:string>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</json:string></affiliations></json:item><json:item><name>A. Fagiolini M.D.</name><affiliations><json:string>Department of Neuroscience, University of Siena School of Medicine, Siena, Italy</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>mood disorders</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>treatment outcome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>personality disorders</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>specificity</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>pharmacotherapy</value></json:item></subject><articleId><json:string>DA20661</json:string></articleId><arkIstex>ark:/67375/WNG-6WCNHBJ6-Q</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Background: Although interpersonal psychotherapy (IPT) is an efficacious treatment for acute depression, the relative efficacy of treatment in each of the four IPT problem areas (grief, role transitions, role disputes, interpersonal deficits) has received little attention. We evaluated the specificity of IPT by comparing treatment success among patients whose psychotherapy focused on each problem area. Moreover, we sought to understand how the patient characteristics and interpersonal problems most closely linked to the onset of a patient's current depression contributed to IPT success. Methods: Patients meeting DSM‐IV criteria for an episode of major depressive disorder (n=182) were treated with weekly IPT. Remission was defined as an average Hamilton Rating Scale for Depression 17‐item score of 7 or below over 3 weeks. Personality disorders were diagnosed using the Structured Clinical Interview for DSM‐IV Personality Disorders. Results: Contrary to our prediction that patients whose treatment was focused on interpersonal deficits would take longer to remit, survival analyses indicated that patients receiving treatment focused on each of the four problem areas did not differ in their times to remission. Nor were patients in the interpersonal deficits group more likely to have an Axis II diagnosis. Patients whose treatment focused on role transitions remitted faster than those whose treatment focused on role disputes, after controlling for covariates. Conclusion: With skillful use of IPT strategies and tactics and with careful medication management where appropriate, patients in this study whose treatment focused on each problem area were treated with equal success by trained IPT clinicians. Depression and Anxiety, 2010. © 2010 Wiley‐Liss, Inc.</abstract><qualityIndicators><refBibsNative>true</refBibsNative><abstractWordCount>256</abstractWordCount><abstractCharCount>1774</abstractCharCount><keywordCount>5</keywordCount><score>9.359</score><pdfWordCount>4359</pdfWordCount><pdfCharCount>28908</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>7</pdfPageCount><pdfPageSize>595.276 x 790.866 pts</pdfPageSize></qualityIndicators><title>Comparative outcomes among the problem areas of interpersonal psychotherapy for depression</title><pmid><json:string>20099274</json:string></pmid><genre><json:string>article</json:string></genre><host><title>Depression and Anxiety</title><language><json:string>unknown</json:string></language><doi><json:string>10.1002/(ISSN)1520-6394</json:string></doi><issn><json:string>1091-4269</json:string></issn><eissn><json:string>1520-6394</json:string></eissn><publisherId><json:string>DA</json:string></publisherId><volume>27</volume><issue>5</issue><pages><first>434</first><last>440</last><total>7</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Research Article</value></json:item></subject></host><namedEntities><unitex><date><json:string>2010</json:string></date><geogName></geogName><orgName><json:string>Department of Neuroscience, University of Siena School of Medicine, Siena, Italy</json:string><json:string>Department of Psychiatry, Western Psychiatric</json:string><json:string>Research Article</json:string><json:string>Western Psychiatric Institute and Clinic</json:string><json:string>Department of Psychiatry, Neurobiology, Pharmacology, and Biotechnology</json:string><json:string>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania</json:string><json:string>Pittsburgh Foundation</json:string><json:string>University of Pittsburgh</json:string><json:string>Department of Psychiatry, Neurobiology, Pharmacology, and Biotechnology of the University of Pisa, Italy</json:string><json:string>Parke-Davis Pharmaceutical Co.</json:string><json:string>Forest Research Institute and Fondazione IDEA</json:string><json:string>University of Pisa, Italy</json:string><json:string>Forest Research Institute, and Lundbeck</json:string><json:string>Ethics Committee of the University of Pisa</json:string><json:string>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</json:string><json:string>Wiley-Liss, Inc.</json:string><json:string>Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania</json:string><json:string>Servier International</json:string><json:string>Institutional Review Board of the University of Pittsburgh</json:string><json:string>Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania</json:string><json:string>American Psychological Association Books</json:string><json:string>Department of Psychiatry, University of Siena, Siena, Italy</json:string><json:string>National Institute of Health</json:string><json:string>University of Pittsburgh Medical Center</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>Rucci</json:string><json:string>P. Houck</json:string><json:string>M. Cyranowski</json:string><json:string>Eli Lilly</json:string><json:string>P. Rucci</json:string><json:string>H.A. Swartz</json:string><json:string>Levenson</json:string><json:string>Cyranowski</json:string><json:string>N. Forgione</json:string><json:string>A. Fagiolini</json:string><json:string>Kimberly McCasky</json:string><json:string>Of</json:string><json:string>Frank</json:string><json:string>Cathy Maihoefer</json:string><json:string>Joan Buttenfield</json:string><json:string>Debra Frankel</json:string><json:string>Dorothy Parks</json:string><json:string>Joel Anderton</json:string><json:string>Cheng</json:string><json:string>Isabella Soreca</json:string><json:string>Swartz</json:string><json:string>Y. Cheng</json:string><json:string>Dana Fleming</json:string><json:string>E. Frank</json:string><json:string>Janney</json:string><json:string>A. Janney</json:string><json:string>Houck</json:string><json:string>Fagiolini</json:string><json:string>D.Econ</json:string></persName><placeName><json:string>Bristol</json:string><json:string>Pittsburgh</json:string><json:string>Pisa</json:string><json:string>Ethnicity</json:string><json:string>PA</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Klerman et al.[1]</json:string><json:string>Frank et al.[16]</json:string><json:string>[18]</json:string><json:string>Levenson et al.</json:string><json:string>[17]</json:string><json:string>[1]</json:string><json:string>Institute and Clinic, 3811</json:string><json:string>Weissman et al.</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-6WCNHBJ6-Q</json:string></ark><categories><inist><json:string>1 - sciences humaines et sociales</json:string></inist></categories><publicationDate>2010</publicationDate><copyrightDate>2010</copyrightDate><doi><json:string>10.1002/da.20661</json:string></doi><id>C36DA6A36C2158534DBF665294024E4663E4D7F0</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/C36DA6A36C2158534DBF665294024E4663E4D7F0/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/C36DA6A36C2158534DBF665294024E4663E4D7F0/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/C36DA6A36C2158534DBF665294024E4663E4D7F0/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Comparative outcomes among the problem areas of interpersonal psychotherapy for depression<ref type="note" target="#fn1"></ref></title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><licence>© 2010 Wiley‐Liss, Inc.</licence></availability><date type="published" when="2010-05"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main" xml:lang="en">Comparative outcomes among the problem areas of interpersonal psychotherapy for depression<ref type="note" target="#fn1"></ref></title><title level="a" type="short" xml:lang="en">Research Article: Problem Areas of Interpersonal Psychotherapy</title><author xml:id="author-0000"><persName><forename type="first">J.C.</forename><surname>Levenson</surname><roleName type="degree">M.S.</roleName></persName><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation><affiliation>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation></author><author xml:id="author-0001" role="corresp"><persName><forename type="first">E.</forename><surname>Frank</surname><roleName type="degree">Ph.D.</roleName></persName><email>franke@upmc.edu</email><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation><affiliation>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation><affiliation>Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Y.</forename><surname>Cheng</surname><roleName type="degree">Ph.D.</roleName></persName><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation><affiliation>Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">P.</forename><surname>Rucci</surname><roleName type="degree">Ph.D.</roleName></persName><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">C.A.</forename><surname>Janney</surname><roleName type="degree">M.S.</roleName></persName><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation><affiliation>Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation></author><author xml:id="author-0005"><persName><forename type="first">P.</forename><surname>Houck</surname><roleName type="degree">M.S.</roleName></persName><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation></author><author xml:id="author-0006"><persName><forename type="first">R.N.</forename><surname>Forgione</surname><roleName type="degree">D.Econ.</roleName></persName><affiliation>Department of Psychiatry, University of Siena, Siena, Italy<address><country key="US"></country></address></affiliation></author><author xml:id="author-0007"><persName><forename type="first">H.A.</forename><surname>Swartz</surname><roleName type="degree">M.D.</roleName></persName><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation></author><author xml:id="author-0008"><persName><forename type="first">J.M.</forename><surname>Cyranowski</surname><roleName type="degree">Ph.D.</roleName></persName><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania<address><country key="US"></country></address></affiliation></author><author xml:id="author-0009"><persName><forename type="first">A.</forename><surname>Fagiolini</surname><roleName type="degree">M.D.</roleName></persName><affiliation>Department of Neuroscience, University of Siena School of Medicine, Siena, Italy<address><country key="IT"></country></address></affiliation></author><idno type="istex">C36DA6A36C2158534DBF665294024E4663E4D7F0</idno><idno type="ark">ark:/67375/WNG-6WCNHBJ6-Q</idno><idno type="DOI">10.1002/da.20661</idno><idno type="unit">DA20661</idno><idno type="toTypesetVersion">file:DA.DA20661.pdf</idno></analytic><monogr><title level="j" type="main">Depression and Anxiety</title><title level="j" type="alt">DEPRESSION AND ANXIETY</title><idno type="pISSN">1091-4269</idno><idno type="eISSN">1520-6394</idno><idno type="book-DOI">10.1002/(ISSN)1520-6394</idno><idno type="book-part-DOI">10.1002/da.v27:5</idno><idno type="product">DA</idno><imprint><biblScope unit="vol">27</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="434">434</biblScope><biblScope unit="page" to="440">440</biblScope><biblScope unit="page-count">7</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-05"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head><p><hi rend="italic">Background:</hi> Although interpersonal psychotherapy (IPT) is an efficacious treatment for acute depression, the relative efficacy of treatment in each of the four IPT problem areas (grief, role transitions, role disputes, interpersonal deficits) has received little attention. We evaluated the specificity of IPT by comparing treatment success among patients whose psychotherapy focused on each problem area. Moreover, we sought to understand how the patient characteristics and interpersonal problems most closely linked to the onset of a patient's current depression contributed to IPT success. <hi rend="italic">Methods:</hi> Patients meeting DSM‐IV criteria for an episode of major depressive disorder (<hi rend="italic"><hi rend="bold">n</hi></hi>=182) were treated with weekly IPT. Remission was defined as an average Hamilton Rating Scale for Depression 17‐item score of 7 or below over 3 weeks. Personality disorders were diagnosed using the Structured Clinical Interview for DSM‐IV Personality Disorders. <hi rend="italic">Results:</hi> Contrary to our prediction that patients whose treatment was focused on interpersonal deficits would take longer to remit, survival analyses indicated that patients receiving treatment focused on each of the four problem areas did not differ in their times to remission. Nor were patients in the interpersonal deficits group more likely to have an Axis II diagnosis. Patients whose treatment focused on role transitions remitted faster than those whose treatment focused on role disputes, after controlling for covariates. <hi rend="italic">Conclusion:</hi> With skillful use of IPT strategies and tactics and with careful medication management where appropriate, patients in this study whose treatment focused on each problem area were treated with equal success by trained IPT clinicians. Depression and Anxiety, 2010. © 2010 Wiley‐Liss, Inc.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="kwd1">mood disorders</term><term xml:id="kwd2">treatment outcome</term><term xml:id="kwd3">personality disorders</term><term xml:id="kwd4">specificity</term><term xml:id="kwd5">pharmacotherapy</term></keywords><keywords rend="articleCategory"><term>Research Article</term></keywords><keywords rend="tocHeading1"><term>Research Articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/C36DA6A36C2158534DBF665294024E4663E4D7F0/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1520-6394</doi><issn type="print">1091-4269</issn><issn type="electronic">1520-6394</issn><idGroup><id type="product" value="DA"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="DEPRESSION AND ANXIETY">Depression and Anxiety</title><title type="short">Depress. Anxiety</title></titleGroup><selfCitationGroup><citation type="ancestor" xml:id="cit1"><journalTitle>Depression</journalTitle><accessionId ref="info:x-wiley/issn/10626417">1062-6417</accessionId><accessionId ref="info:x-wiley/issn/15227162">1522-7162</accessionId><pubYear year="1996">1996</pubYear><vol>4</vol><issue>2</issue></citation><citation type="ancestor" xml:id="cit2"><journalTitle>Anxiety</journalTitle><accessionId ref="info:x-wiley/issn/10709797">1070-9797</accessionId><accessionId ref="info:x-wiley/issn/15227154">1522-7154</accessionId><pubYear year="1996">1996</pubYear><vol>2</vol><issue>5</issue></citation></selfCitationGroup></publicationMeta><publicationMeta level="part" position="50"><doi origin="wiley" registered="yes">10.1002/da.v27:5</doi><numberingGroup><numbering type="journalVolume" number="27">27</numbering><numbering type="journalIssue">5</numbering></numberingGroup><coverDate startDate="2010-05">May 2010</coverDate></publicationMeta><publicationMeta level="unit" 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Psychotherapy</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1 #af2"><personName><givenNames>J.C.</givenNames><familyName>Levenson</familyName><degrees>M.S.</degrees></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1 #af2" corresponding="yes"><personName><givenNames>E.</givenNames><familyName>Frank</familyName><degrees>Ph.D.</degrees></personName><contactDetails><email>franke@upmc.edu</email></contactDetails></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1 #af3"><personName><givenNames>Y.</givenNames><familyName>Cheng</familyName><degrees>Ph.D.</degrees></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af1"><personName><givenNames>P.</givenNames><familyName>Rucci</familyName><degrees>Ph.D.</degrees></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1 #af4"><personName><givenNames>C.A.</givenNames><familyName>Janney</familyName><degrees>M.S.</degrees></personName></creator><creator xml:id="au6" creatorRole="author" affiliationRef="#af1"><personName><givenNames>P.</givenNames><familyName>Houck</familyName><degrees>M.S.</degrees></personName></creator><creator xml:id="au7" creatorRole="author" affiliationRef="#af5"><personName><givenNames>R.N.</givenNames><familyName>Forgione</familyName><degrees>D.Econ.</degrees></personName></creator><creator xml:id="au8" creatorRole="author" affiliationRef="#af1"><personName><givenNames>H.A.</givenNames><familyName>Swartz</familyName><degrees>M.D.</degrees></personName></creator><creator xml:id="au9" creatorRole="author" affiliationRef="#af1"><personName><givenNames>J.M.</givenNames><familyName>Cyranowski</familyName><degrees>Ph.D.</degrees></personName></creator><creator xml:id="au10" creatorRole="author" affiliationRef="#af6"><personName><givenNames>A.</givenNames><familyName>Fagiolini</familyName><degrees>M.D.</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="US" type="organization"><unparsedAffiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="US" type="organization"><unparsedAffiliation>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="US" type="organization"><unparsedAffiliation>Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania</unparsedAffiliation></affiliation><affiliation xml:id="af4" countryCode="US" type="organization"><unparsedAffiliation>Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania</unparsedAffiliation></affiliation><affiliation xml:id="af5" countryCode="US" type="organization"><unparsedAffiliation>Department of Psychiatry, University of Siena, Siena, Italy</unparsedAffiliation></affiliation><affiliation xml:id="af6" countryCode="IT" type="organization"><unparsedAffiliation>Department of Neuroscience, University of Siena School of Medicine, Siena, Italy</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">mood disorders</keyword><keyword xml:id="kwd2">treatment outcome</keyword><keyword xml:id="kwd3">personality disorders</keyword><keyword xml:id="kwd4">specificity</keyword><keyword xml:id="kwd5">pharmacotherapy</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p><i>Background:</i> Although interpersonal psychotherapy (IPT) is an efficacious treatment for acute depression, the relative efficacy of treatment in each of the four IPT problem areas (grief, role transitions, role disputes, interpersonal deficits) has received little attention. We evaluated the specificity of IPT by comparing treatment success among patients whose psychotherapy focused on each problem area. Moreover, we sought to understand how the patient characteristics and interpersonal problems most closely linked to the onset of a patient's current depression contributed to IPT success. <i>Methods:</i> Patients meeting DSM‐IV criteria for an episode of major depressive disorder (<i><b>n</b></i>=182) were treated with weekly IPT. Remission was defined as an average Hamilton Rating Scale for Depression 17‐item score of 7 or below over 3 weeks. Personality disorders were diagnosed using the Structured Clinical Interview for DSM‐IV Personality Disorders. <i>Results:</i> Contrary to our prediction that patients whose treatment was focused on interpersonal deficits would take longer to remit, survival analyses indicated that patients receiving treatment focused on each of the four problem areas did not differ in their times to remission. Nor were patients in the interpersonal deficits group more likely to have an Axis II diagnosis. Patients whose treatment focused on role transitions remitted faster than those whose treatment focused on role disputes, after controlling for covariates. <i>Conclusion:</i> With skillful use of IPT strategies and tactics and with careful medication management where appropriate, patients in this study whose treatment focused on each problem area were treated with equal success by trained IPT clinicians. Depression and Anxiety, 2010. © 2010 Wiley‐Liss, Inc.</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><label>*</label><p><i>The authors disclose the following financial relationships within the past 3 years</i>: Dr. Fagiolini is a speaker and/or a consultant for Boeringer Ingelheim, Bristol Myers Squibb, Eli Lilly, Jannssen, Lundbeck, Novartis, Pfizer, and Takeda. Dr. Rucci has received support from Forest Research Institute and Fondazione IDEA. Dr. Forgione has prepared slides for Bristol‐Myers Squibb personnel training. Dr. Frank has received support from Servier International, Guilford Press, Forest Research Institute, and Lundbeck. Dr. Cyranowski has received support from the National Institute of Health and the Pittsburgh Foundation. She has no conflict of interest to report with respect to this study. Dr. Swartz has served as a speaker for Astra Zeneca, Eli Lilly, and Bristol Myers Squibb, has served on the advisory boards of Novartis and Bristol Myers Squibb, has received an honorarium from Servier for book chapter, and has received grant support from Bristol Myers Squibb. Ms. Janney served as Pfizer legal consultant while employed at Parke‐Davis Pharmaceutical Co. Other financial support has come from the University of Pittsburgh. Ms. Levenson anticipates royalties from American Psychological Association Books. Dr. Cheng and Ms. Houck have no conflicts to report.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Comparative outcomes among the problem areas of interpersonal psychotherapy for depression</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Research Article: Problem Areas of Interpersonal Psychotherapy</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Comparative outcomes among the problem areas of interpersonal psychotherapy for depression</title></titleInfo><name type="personal"><namePart type="given">J.C.</namePart><namePart type="family">Levenson</namePart><namePart type="termsOfAddress">M.S.</namePart><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</affiliation><affiliation>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E.</namePart><namePart type="family">Frank</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</affiliation><affiliation>Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania</affiliation><affiliation>E-mail: franke@upmc.edu</affiliation><affiliation>Correspondence address: Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y.</namePart><namePart type="family">Cheng</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</affiliation><affiliation>Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P.</namePart><namePart type="family">Rucci</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C.A.</namePart><namePart type="family">Janney</namePart><namePart type="termsOfAddress">M.S.</namePart><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</affiliation><affiliation>Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P.</namePart><namePart type="family">Houck</namePart><namePart type="termsOfAddress">M.S.</namePart><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R.N.</namePart><namePart type="family">Forgione</namePart><namePart type="termsOfAddress">D.Econ.</namePart><affiliation>Department of Psychiatry, University of Siena, Siena, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H.A.</namePart><namePart type="family">Swartz</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J.M.</namePart><namePart type="family">Cyranowski</namePart><namePart type="termsOfAddress">Ph.D.</namePart><affiliation>Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A.</namePart><namePart type="family">Fagiolini</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Department of Neuroscience, University of Siena School of Medicine, Siena, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2010-05</dateIssued><dateCaptured encoding="w3cdtf">2009-07-07</dateCaptured><dateValid encoding="w3cdtf">2009-12-14</dateValid><copyrightDate encoding="w3cdtf">2010</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">1</extent><extent unit="tables">2</extent><extent unit="references">19</extent></physicalDescription><abstract lang="en">Background: Although interpersonal psychotherapy (IPT) is an efficacious treatment for acute depression, the relative efficacy of treatment in each of the four IPT problem areas (grief, role transitions, role disputes, interpersonal deficits) has received little attention. We evaluated the specificity of IPT by comparing treatment success among patients whose psychotherapy focused on each problem area. Moreover, we sought to understand how the patient characteristics and interpersonal problems most closely linked to the onset of a patient's current depression contributed to IPT success. Methods: Patients meeting DSM‐IV criteria for an episode of major depressive disorder (n=182) were treated with weekly IPT. Remission was defined as an average Hamilton Rating Scale for Depression 17‐item score of 7 or below over 3 weeks. Personality disorders were diagnosed using the Structured Clinical Interview for DSM‐IV Personality Disorders. Results: Contrary to our prediction that patients whose treatment was focused on interpersonal deficits would take longer to remit, survival analyses indicated that patients receiving treatment focused on each of the four problem areas did not differ in their times to remission. Nor were patients in the interpersonal deficits group more likely to have an Axis II diagnosis. Patients whose treatment focused on role transitions remitted faster than those whose treatment focused on role disputes, after controlling for covariates. Conclusion: With skillful use of IPT strategies and tactics and with careful medication management where appropriate, patients in this study whose treatment focused on each problem area were treated with equal success by trained IPT clinicians. Depression and Anxiety, 2010. © 2010 Wiley‐Liss, Inc.</abstract><note type="content">*The authors disclose the following financial relationships within the past 3 years: Dr. Fagiolini is a speaker and/or a consultant for Boeringer Ingelheim, Bristol Myers Squibb, Eli Lilly, Jannssen, Lundbeck, Novartis, Pfizer, and Takeda. Dr. Rucci has received support from Forest Research Institute and Fondazione IDEA. Dr. Forgione has prepared slides for Bristol‐Myers Squibb personnel training. Dr. Frank has received support from Servier International, Guilford Press, Forest Research Institute, and Lundbeck. Dr. Cyranowski has received support from the National Institute of Health and the Pittsburgh Foundation. She has no conflict of interest to report with respect to this study. Dr. Swartz has served as a speaker for Astra Zeneca, Eli Lilly, and Bristol Myers Squibb, has served on the advisory boards of Novartis and Bristol Myers Squibb, has received an honorarium from Servier for book chapter, and has received grant support from Bristol Myers Squibb. Ms. Janney served as Pfizer legal consultant while employed at Parke‐Davis Pharmaceutical Co. Other financial support has come from the University of Pittsburgh. Ms. Levenson anticipates royalties from American Psychological Association Books. Dr. Cheng and Ms. Houck have no conflicts to report.</note><subject lang="en"><genre>keywords</genre><topic>mood disorders</topic><topic>treatment outcome</topic><topic>personality disorders</topic><topic>specificity</topic><topic>pharmacotherapy</topic></subject><relatedItem type="host"><titleInfo><title>Depression and Anxiety</title></titleInfo><titleInfo type="abbreviated"><title>Depress. Anxiety</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Research Article</topic></subject><identifier type="ISSN">1091-4269</identifier><identifier type="eISSN">1520-6394</identifier><identifier type="DOI">10.1002/(ISSN)1520-6394</identifier><identifier type="PublisherID">DA</identifier><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>27</number></detail><detail type="issue"><caption>no.</caption><number>5</number></detail><extent unit="pages"><start>434</start><end>440</end><total>7</total></extent></part></relatedItem><relatedItem type="preceding"><titleInfo><title>DepressionAnxiety</title></titleInfo><identifier type="ISSN">1062-6417</identifier><identifier type="ISSN">1522-7162</identifier><identifier type="ISSN">1070-9797</identifier><identifier type="ISSN">1522-7154</identifier><part><date point="end">1996</date><detail type="volume"><caption>last vol.</caption><number>4</number></detail><detail type="issue"><caption>last no.</caption><number>2</number></detail></part></relatedItem><identifier type="istex">C36DA6A36C2158534DBF665294024E4663E4D7F0</identifier><identifier type="ark">ark:/67375/WNG-6WCNHBJ6-Q</identifier><identifier type="DOI">10.1002/da.20661</identifier><identifier type="ArticleID">DA20661</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2010 Wiley‐Liss, Inc.</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/C36DA6A36C2158534DBF665294024E4663E4D7F0/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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