ParkinsonCanadaV1, PubMed, Checkpoint, bibRecord, 000633

The effect of medication and the role of postural instability in different components of freezing of gait (FOG).

Identifieur interne : 000633 ( PubMed/Checkpoint ); précédent : 000632; suivant : 000634

The effect of medication and the role of postural instability in different components of freezing of gait (FOG).

Auteurs : Julie Nantel [Canada] ; Helen Bronte-Stewart [États-Unis]

Source :

Parkinsonism & related disorders [ 1873-5126 ] ; 2014.

RBID : pubmed:24530016

English descriptors

KwdEn :
- Antiparkinson Agents (therapeutic use), Female, Gait (drug effects), Gait Disorders, Neurologic (etiology), Humans, Male, Parkinson Disease (complications), Parkinson Disease (drug therapy), Postural Balance (drug effects).
MESH :
- chemical , therapeutic use : Antiparkinson Agents.
- complications : Parkinson Disease.
- drug effects : Gait, Postural Balance.
- drug therapy : Parkinson Disease.
- etiology : Gait Disorders, Neurologic.
- Female, Humans, Male.

Abstract

Freezing of gait (FOG) is associated with gait asymmetry and arrhythmicity, cognitive impairment in Parkinson's disease (PD). However, the role of postural instability (PI) in and the effect of dopaminergic medication (meds) on FOG are unclear. We investigated the effect of meds on FOG using a validated metric, Stepping in Place (SIP) and the relationship between PI and FOG.

DOI: 10.1016/j.parkreldis.2014.01.017
PubMed: 24530016

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 000774
to stream PubMed, to step Curation: 000774

Links to Exploration step

pubmed:24530016

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The effect of medication and the role of postural instability in different components of freezing of gait (FOG).</title>
<author><name sortKey="Nantel, Julie" sort="Nantel, Julie" uniqKey="Nantel J" first="Julie" last="Nantel">Julie Nantel</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Human Kinetics, Faculty of Health Sciences, Ottawa University, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>School of Human Kinetics, Faculty of Health Sciences, Ottawa University</wicri:regionArea>
<wicri:noRegion>Ottawa University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bronte Stewart, Helen" sort="Bronte Stewart, Helen" uniqKey="Bronte Stewart H" first="Helen" last="Bronte-Stewart">Helen Bronte-Stewart</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology and Neurological Sciences, Stanford University, CA, USA; Department Neurosurgery, Stanford University, CA, USA. Electronic address: hbs@stanford.edu.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology and Neurological Sciences, Stanford University, CA, USA; Department Neurosurgery, Stanford University, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2014">2014</date>
<idno type="RBID">pubmed:24530016</idno>
<idno type="pmid">24530016</idno>
<idno type="doi">10.1016/j.parkreldis.2014.01.017</idno>
<idno type="wicri:Area/PubMed/Corpus">000774</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000774</idno>
<idno type="wicri:Area/PubMed/Curation">000774</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000774</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000774</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000774</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The effect of medication and the role of postural instability in different components of freezing of gait (FOG).</title>
<author><name sortKey="Nantel, Julie" sort="Nantel, Julie" uniqKey="Nantel J" first="Julie" last="Nantel">Julie Nantel</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Human Kinetics, Faculty of Health Sciences, Ottawa University, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>School of Human Kinetics, Faculty of Health Sciences, Ottawa University</wicri:regionArea>
<wicri:noRegion>Ottawa University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bronte Stewart, Helen" sort="Bronte Stewart, Helen" uniqKey="Bronte Stewart H" first="Helen" last="Bronte-Stewart">Helen Bronte-Stewart</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Neurology and Neurological Sciences, Stanford University, CA, USA; Department Neurosurgery, Stanford University, CA, USA. Electronic address: hbs@stanford.edu.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology and Neurological Sciences, Stanford University, CA, USA; Department Neurosurgery, Stanford University, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Parkinsonism & related disorders</title>
<idno type="eISSN">1873-5126</idno>
<imprint><date when="2014" type="published">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiparkinson Agents (therapeutic use)</term>
<term>Female</term>
<term>Gait (drug effects)</term>
<term>Gait Disorders, Neurologic (etiology)</term>
<term>Humans</term>
<term>Male</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Postural Balance (drug effects)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Gait</term>
<term>Postural Balance</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Gait Disorders, Neurologic</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Humans</term>
<term>Male</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Freezing of gait (FOG) is associated with gait asymmetry and arrhythmicity, cognitive impairment in Parkinson's disease (PD). However, the role of postural instability (PI) in and the effect of dopaminergic medication (meds) on FOG are unclear. We investigated the effect of meds on FOG using a validated metric, Stepping in Place (SIP) and the relationship between PI and FOG.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24530016</PMID>
<DateCreated><Year>2014</Year>
<Month>04</Month>
<Day>14</Day>
</DateCreated>
<DateCompleted><Year>2014</Year>
<Month>12</Month>
<Day>03</Day>
</DateCompleted>
<DateRevised><Year>2014</Year>
<Month>04</Month>
<Day>14</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-5126</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>20</Volume>
<Issue>4</Issue>
<PubDate><Year>2014</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Parkinsonism & related disorders</Title>
<ISOAbbreviation>Parkinsonism Relat. Disord.</ISOAbbreviation>
</Journal>
<ArticleTitle>The effect of medication and the role of postural instability in different components of freezing of gait (FOG).</ArticleTitle>
<Pagination><MedlinePgn>447-51</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.parkreldis.2014.01.017</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S1353-8020(14)00032-7</ELocationID>
<Abstract><AbstractText Label="UNLABELLED">Freezing of gait (FOG) is associated with gait asymmetry and arrhythmicity, cognitive impairment in Parkinson's disease (PD). However, the role of postural instability (PI) in and the effect of dopaminergic medication (meds) on FOG are unclear. We investigated the effect of meds on FOG using a validated metric, Stepping in Place (SIP) and the relationship between PI and FOG.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We assessed static posturography (off meds), SIP, UPDRS-III (off/on meds) and the FOG-questionnaire (FOG-Q) in 15 freezers/15 non-freezers and 14 healthy controls.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">UPDRS-III, rigidity, tremor (P < 0.01) and axial subscores (P < 0.05) improved with meds in freezers. Only UPDRS-III and tremor improved in non-freezers (P < 0.01). Meds improved freezing episode (FE) frequency, duration and stride duration in freezers (P < 0.01). Over 73% of freezers did not freeze on meds, although one freezer had more and longer duration FEs. Meds did not improve SIP cycle asymmetry and arrhythmicity, which remained greater in freezers compared to other groups on and off meds (P < 0.01, P < 0.05 respectively). Center of pressure (CoP) mediolateral displacement and velocity (VCoP) in both directions were larger in freezers (P < 0.05). FOG-Q was correlated with CoP anteroposterior displacement and mediolateral VCoP (R = 0.42; R = 0.40, P < 0.05). The improvement of FOG frequency and duration but not of gait asymmetry and arrhythmicity on meds suggests that both dopaminergic and non-dopaminergic networks contribute to FOG. The correlations between postural instability and FOG severity and SIP asymmetry on meds, suggest that as the disease progresses, postural instability interferes with gait symmetry and lead to on meds FOG and falls.</AbstractText>
<CopyrightInformation>Copyright © 2014 Elsevier Ltd. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nantel</LastName>
<ForeName>Julie</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>School of Human Kinetics, Faculty of Health Sciences, Ottawa University, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bronte-Stewart</LastName>
<ForeName>Helen</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Department of Neurology and Neurological Sciences, Stanford University, CA, USA; Department Neurosurgery, Stanford University, CA, USA. Electronic address: hbs@stanford.edu.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>01</Month>
<Day>28</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Parkinsonism Relat Disord</MedlineTA>
<NlmUniqueID>9513583</NlmUniqueID>
<ISSNLinking>1353-8020</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000978">Antiparkinson Agents</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000978" MajorTopicYN="N">Antiparkinson Agents</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005684" MajorTopicYN="N">Gait</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020233" MajorTopicYN="N">Gait Disorders, Neurologic</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004856" MajorTopicYN="N">Postural Balance</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Dopaminergic networks</Keyword>
<Keyword MajorTopicYN="N">Freezing of gait</Keyword>
<Keyword MajorTopicYN="N">Medication</Keyword>
<Keyword MajorTopicYN="N">Parkinson's disease</Keyword>
<Keyword MajorTopicYN="N">Postural instability</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year>
<Month>09</Month>
<Day>20</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2014</Year>
<Month>01</Month>
<Day>07</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2014</Year>
<Month>01</Month>
<Day>16</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2014</Year>
<Month>2</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2014</Year>
<Month>2</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2014</Year>
<Month>12</Month>
<Day>15</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">24530016</ArticleId>
<ArticleId IdType="pii">S1353-8020(14)00032-7</ArticleId>
<ArticleId IdType="doi">10.1016/j.parkreldis.2014.01.017</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Canada</li>
<li>États-Unis</li>
</country>
<region><li>Californie</li>
</region>
</list>
<tree><country name="Canada"><noRegion><name sortKey="Nantel, Julie" sort="Nantel, Julie" uniqKey="Nantel J" first="Julie" last="Nantel">Julie Nantel</name>
</noRegion>
</country>
<country name="États-Unis"><region name="Californie"><name sortKey="Bronte Stewart, Helen" sort="Bronte Stewart, Helen" uniqKey="Bronte Stewart H" first="Helen" last="Bronte-Stewart">Helen Bronte-Stewart</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000633 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000633 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Canada
   |area=    ParkinsonCanadaV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:24530016
   |texte=   The effect of medication and the role of postural instability in different components of freezing of gait (FOG).
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:24530016" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a ParkinsonCanadaV1

This area was generated with Dilib version V0.6.29.
Data generation: Thu May 4 22:20:19 2017. Site generation: Fri Dec 23 23:17:26 2022

	La maladie de Parkinson au Canada (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

La maladie de Parkinson au Canada (serveur d'exploration)

The effect of medication and the role of postural instability in different components of freezing of gait (FOG).

The effect of medication and the role of postural instability in different components of freezing of gait (FOG).

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki