Effects of subthalamic nucleus stimulation on motor cortex plasticity in Parkinson disease.
Identifieur interne : 000530 ( PubMed/Checkpoint ); précédent : 000529; suivant : 000531Effects of subthalamic nucleus stimulation on motor cortex plasticity in Parkinson disease.
Auteurs : Sang Jin Kim [Corée du Sud] ; Kaviraja Udupa [Corée du Sud] ; Zhen Ni [Corée du Sud] ; Elena Moro [Corée du Sud] ; Carolyn Gunraj [Corée du Sud] ; Filomena Mazzella [Corée du Sud] ; Andres M. Lozano [Corée du Sud] ; Mojgan Hodaie [Corée du Sud] ; Anthony E. Lang [Corée du Sud] ; Robert Chen [Corée du Sud]Source :
- Neurology [ 1526-632X ] ; 2015.
English descriptors
- KwdEn :
- Aged, Deep Brain Stimulation (trends), Evoked Potentials, Motor (physiology), Female, Humans, Long-Term Potentiation (physiology), Male, Middle Aged, Motor Cortex (physiology), Neuronal Plasticity (physiology), Parkinson Disease (physiopathology), Parkinson Disease (therapy), Subthalamic Nucleus (physiology), Treatment Outcome.
- MESH :
- physiology : Evoked Potentials, Motor, Long-Term Potentiation, Motor Cortex, Neuronal Plasticity, Subthalamic Nucleus.
- physiopathology : Parkinson Disease.
- therapy : Parkinson Disease.
- trends : Deep Brain Stimulation.
- Aged, Female, Humans, Male, Middle Aged, Treatment Outcome.
Abstract
We hypothesized that subthalamic nucleus (STN) deep brain stimulation (DBS) will improve long-term potentiation (LTP)-like plasticity in motor cortex in Parkinson disease (PD).
DOI: 10.1212/WNL.0000000000001806
PubMed: 26156511
Affiliations:
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pubmed:26156511Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effects of subthalamic nucleus stimulation on motor cortex plasticity in Parkinson disease.</title><author><name sortKey="Kim, Sang Jin" sort="Kim, Sang Jin" uniqKey="Kim S" first="Sang Jin" last="Kim">Sang Jin Kim</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Udupa, Kaviraja" sort="Udupa, Kaviraja" uniqKey="Udupa K" first="Kaviraja" last="Udupa">Kaviraja Udupa</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Ni, Zhen" sort="Ni, Zhen" uniqKey="Ni Z" first="Zhen" last="Ni">Zhen Ni</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Gunraj, Carolyn" sort="Gunraj, Carolyn" uniqKey="Gunraj C" first="Carolyn" last="Gunraj">Carolyn Gunraj</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Mazzella, Filomena" sort="Mazzella, Filomena" uniqKey="Mazzella F" first="Filomena" last="Mazzella">Filomena Mazzella</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hodaie, Mojgan" sort="Hodaie, Mojgan" uniqKey="Hodaie M" first="Mojgan" last="Hodaie">Mojgan Hodaie</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Chen, Robert" sort="Chen, Robert" uniqKey="Chen R" first="Robert" last="Chen">Robert Chen</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea. robert.chen@uhn.ca.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26156511</idno><idno type="pmid">26156511</idno><idno type="doi">10.1212/WNL.0000000000001806</idno><idno type="wicri:Area/PubMed/Corpus">000442</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000442</idno><idno type="wicri:Area/PubMed/Curation">000442</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000442</idno><idno type="wicri:Area/PubMed/Checkpoint">000442</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000442</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Effects of subthalamic nucleus stimulation on motor cortex plasticity in Parkinson disease.</title><author><name sortKey="Kim, Sang Jin" sort="Kim, Sang Jin" uniqKey="Kim S" first="Sang Jin" last="Kim">Sang Jin Kim</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Udupa, Kaviraja" sort="Udupa, Kaviraja" uniqKey="Udupa K" first="Kaviraja" last="Udupa">Kaviraja Udupa</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Ni, Zhen" sort="Ni, Zhen" uniqKey="Ni Z" first="Zhen" last="Ni">Zhen Ni</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Gunraj, Carolyn" sort="Gunraj, Carolyn" uniqKey="Gunraj C" first="Carolyn" last="Gunraj">Carolyn Gunraj</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Mazzella, Filomena" sort="Mazzella, Filomena" uniqKey="Mazzella F" first="Filomena" last="Mazzella">Filomena Mazzella</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Hodaie, Mojgan" sort="Hodaie, Mojgan" uniqKey="Hodaie M" first="Mojgan" last="Hodaie">Mojgan Hodaie</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Chen, Robert" sort="Chen, Robert" uniqKey="Chen R" first="Robert" last="Chen">Robert Chen</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea. robert.chen@uhn.ca.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author></analytic><series><title level="j">Neurology</title><idno type="eISSN">1526-632X</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Deep Brain Stimulation (trends)</term><term>Evoked Potentials, Motor (physiology)</term><term>Female</term><term>Humans</term><term>Long-Term Potentiation (physiology)</term><term>Male</term><term>Middle Aged</term><term>Motor Cortex (physiology)</term><term>Neuronal Plasticity (physiology)</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (therapy)</term><term>Subthalamic Nucleus (physiology)</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Evoked Potentials, Motor</term><term>Long-Term Potentiation</term><term>Motor Cortex</term><term>Neuronal Plasticity</term><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="trends" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We hypothesized that subthalamic nucleus (STN) deep brain stimulation (DBS) will improve long-term potentiation (LTP)-like plasticity in motor cortex in Parkinson disease (PD).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26156511</PMID><DateCreated><Year>2015</Year><Month>08</Month><Day>05</Day></DateCreated><DateCompleted><Year>2015</Year><Month>10</Month><Day>26</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>20</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1526-632X</ISSN><JournalIssue CitedMedium="Internet"><Volume>85</Volume><Issue>5</Issue><PubDate><Year>2015</Year><Month>Aug</Month><Day>04</Day></PubDate></JournalIssue><Title>Neurology</Title><ISOAbbreviation>Neurology</ISOAbbreviation></Journal><ArticleTitle>Effects of subthalamic nucleus stimulation on motor cortex plasticity in Parkinson disease.</ArticleTitle><Pagination><MedlinePgn>425-32</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1212/WNL.0000000000001806</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">We hypothesized that subthalamic nucleus (STN) deep brain stimulation (DBS) will improve long-term potentiation (LTP)-like plasticity in motor cortex in Parkinson disease (PD).</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We studied 8 patients with PD treated with STN-DBS and 9 age-matched healthy controls. Patients with PD were studied in 4 sessions in medication (Med) OFF/stimulator (Stim) OFF, Med-OFF/Stim-ON, Med-ON/Stim-OFF, and Med-ON/Stim-ON states in random order. Motor evoked potential amplitude and cortical silent period duration were measured at baseline before paired associated stimulation (PAS) and at 3 different time intervals (T0, T30, T60) up to 60 minutes after PAS in the abductor pollicis brevis and abductor digiti minimi muscles.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Motor evoked potential size significantly increased after PAS in controls (+67.7% of baseline at T30) and in patients in the Med-ON/Stim-ON condition (+55.8% of baseline at T30), but not in patients in the Med-OFF/Stim-OFF (-0.4% of baseline at T30), Med-OFF/Stim-ON (+10.3% of baseline at T30), and Med-ON/Stim-OFF conditions (+17.3% of baseline at T30). Cortical silent period duration increased after PAS in controls but not in patients in all test conditions.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Our findings suggest that STN-DBS together with dopaminergic medications restore LTP-like plasticity in motor cortex in PD. Restoration of cortical plasticity may be one of the mechanisms of how STN-DBS produces clinical benefit.</AbstractText><CopyrightInformation>© 2015 American Academy of Neurology.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Sang Jin</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Udupa</LastName><ForeName>Kaviraja</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ni</LastName><ForeName>Zhen</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moro</LastName><ForeName>Elena</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gunraj</LastName><ForeName>Carolyn</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mazzella</LastName><ForeName>Filomena</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lozano</LastName><ForeName>Andres M</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hodaie</LastName><ForeName>Mojgan</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lang</LastName><ForeName>Anthony E</ForeName><Initials>AE</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Robert</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>From the Division of Neurology (S.J.K., K.U., Z.N., E.M., C.G., F.M., A.E.L., R.C.), University of Toronto, Toronto Western Research Institute, University Health Network and the Edmond J. Safra Program in Parkinson's Disease, Toronto; Division of Neurosurgery and Toronto Western Research Institute (A.M.L., M.H.), University Health Network, University of Toronto; Brain & Spinal Cord Rehab Program (F.M.), Toronto Rehab, University Health Network, Canada; Service de Neurologie (E.M.), CHU Grenoble, Joseph Fourier University, Grenoble, France; and Department of Neurology (S.J.K.), Inje University College of Medicine, Busan, South Korea. robert.chen@uhn.ca.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>MOP 15128</GrantID><Agency>Canadian Institutes of Health Research</Agency><Country>Canada</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>07</Month><Day>08</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Neurology</MedlineTA><NlmUniqueID>0401060</NlmUniqueID><ISSNLinking>0028-3878</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Neuron. 2012 Dec 6;76(5):1030-41</RefSource><PMID Version="1">23217750</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Front Neurol. 2013 Sep 04;4:128</RefSource><PMID Version="1">24027555</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2003 May;126(Pt 5):1146-63</RefSource><PMID Version="1">12690054</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 2013 Sep;84(9):1020-8</RefSource><PMID Version="1">23616568</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trends Neurosci. 2007 May;30(5):211-9</RefSource><PMID Version="1">17367873</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cereb Cortex. 2010 Aug;20(8):1926-36</RefSource><PMID Version="1">20019146</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2013 Feb 14;368(7):610-22</RefSource><PMID Version="1">23406026</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Exp Neurol. 2007 Jul;206(1):80-5</RefSource><PMID Version="1">17498697</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2010 Apr 15;25(5):560-9</RefSource><PMID Version="1">20131394</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2006 Oct;129(Pt 10):2709-21</RefSource><PMID Version="1">16921180</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2003 Dec;126(Pt 12):2586-96</RefSource><PMID Version="1">14506068</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2009 Feb;132(Pt 2):309-18</RefSource><PMID Version="1">19050033</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurophysiol. 1999 Dec;82(6):3575-9</RefSource><PMID Version="1">10601483</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2012 Jun;27(7):864-73</RefSource><PMID Version="1">22648508</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Neurol. 1991 Sep;30(3):365-74</RefSource><PMID Version="1">1683212</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2002 Jun 11;58(11):1665-72</RefSource><PMID Version="1">12058096</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2005 Apr;20(4):395-402</RefSource><PMID Version="1">15719415</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2000 Mar;123 Pt 3:572-84</RefSource><PMID Version="1">10686179</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Science. 2009 Apr 17;324(5925):354-9</RefSource><PMID Version="1">19299587</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2002 Nov;125(Pt 11):2408-17</RefSource><PMID Version="1">12390968</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2003 Jan 14;60(1):78-81</RefSource><PMID Version="1">12525722</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parkinsonism Relat Disord. 2007;13 Suppl 3:S434-6</RefSource><PMID Version="1">18267278</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2011 Aug 15;26(10):1913-21</RefSource><PMID Version="1">21547950</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurotherapeutics. 2008 Jan;5(1):14-25</RefSource><PMID Version="1">18164480</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parkinsonism Relat Disord. 2004 Jul;10(5):305-13</RefSource><PMID Version="1">15196510</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2003 Aug;126(Pt 8):1883-94</RefSource><PMID Version="1">12805105</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2007 Jan 30;68(5):356-63</RefSource><PMID Version="1">17261682</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Neurol. 2006 Jan;59(1):60-71</RefSource><PMID Version="1">16240372</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2011 Aug;134(Pt 8):2312-20</RefSource><PMID Version="1">21742734</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2012 May 1;78(18):1441-8</RefSource><PMID Version="1">22517098</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2003 Apr;18(4):357-63</RefSource><PMID Version="1">12671940</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cleve Clin J Med. 2008 Mar;75 Suppl 2:S59-65</RefSource><PMID Version="1">18540149</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cereb Cortex. 2014 Aug;24(8):2055-67</RefSource><PMID Version="1">23535177</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 1999 Apr;66(4):549-50</RefSource><PMID Version="1">10201440</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2008 Jan 30;23(2):218-27</RefSource><PMID Version="1">18044706</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Neurosci. 2003 May;6(5):501-6</RefSource><PMID Version="1">12665799</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2006 Apr;129(Pt 4):1059-69</RefSource><PMID Version="1">16476674</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2001 May;16(3):448-58</RefSource><PMID Version="1">11391738</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D046690" MajorTopicYN="N">Deep Brain Stimulation</DescriptorName><QualifierName UI="Q000639" MajorTopicYN="Y">trends</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019054" MajorTopicYN="N">Evoked Potentials, Motor</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017774" MajorTopicYN="N">Long-Term Potentiation</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009044" MajorTopicYN="N">Motor Cortex</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009473" MajorTopicYN="N">Neuronal Plasticity</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020531" MajorTopicYN="N">Subthalamic Nucleus</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC4534071</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>11</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>04</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>7</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>7</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>10</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26156511</ArticleId><ArticleId IdType="pii">WNL.0000000000001806</ArticleId><ArticleId IdType="doi">10.1212/WNL.0000000000001806</ArticleId><ArticleId IdType="pmc">PMC4534071</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Corée du Sud</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Corée du Sud"><region name="Ontario"><name sortKey="Kim, Sang Jin" sort="Kim, Sang Jin" uniqKey="Kim S" first="Sang Jin" last="Kim">Sang Jin Kim</name></region><name sortKey="Chen, Robert" sort="Chen, Robert" uniqKey="Chen R" first="Robert" last="Chen">Robert Chen</name><name sortKey="Gunraj, Carolyn" sort="Gunraj, Carolyn" uniqKey="Gunraj C" first="Carolyn" last="Gunraj">Carolyn Gunraj</name><name sortKey="Hodaie, Mojgan" sort="Hodaie, Mojgan" uniqKey="Hodaie M" first="Mojgan" last="Hodaie">Mojgan Hodaie</name><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name><name sortKey="Mazzella, Filomena" sort="Mazzella, Filomena" uniqKey="Mazzella F" first="Filomena" last="Mazzella">Filomena Mazzella</name><name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name><name sortKey="Ni, Zhen" sort="Ni, Zhen" uniqKey="Ni Z" first="Zhen" last="Ni">Zhen Ni</name><name sortKey="Udupa, Kaviraja" sort="Udupa, Kaviraja" uniqKey="Udupa K" first="Kaviraja" last="Udupa">Kaviraja Udupa</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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