Hearing, mobility, and pain predict mortality: a longitudinal population-based study
Identifieur interne : 000848 ( Pmc/Curation ); précédent : 000847; suivant : 000849Hearing, mobility, and pain predict mortality: a longitudinal population-based study
Auteurs : David Feeny [États-Unis, Canada] ; Nathalie Huguet [États-Unis] ; Bentson H. Mcfarland [États-Unis] ; Mark S. Kaplan [États-Unis] ; Heather Orpana [Canada] ; Elizabeth Eckstrom [États-Unis]Source :
- Journal of clinical epidemiology [ 0895-4356 ] ; 2012.
Abstract
Measures of health-related quality of life (HRQL), including the Health Utilities Index Mark 3 (HUI3) are predictive of mortality. HUI3 includes eight attributes, vision, hearing, speech, ambulation, dexterity, cognition, emotion, and pain and discomfort, with five or six levels per attribute that vary from no to severe disability. This study examined associations between individual HUI3 attributes and mortality.
Baseline data and 12 years of follow-up data from a closed longitudinal cohort study, the 1994/95 Canadian National Population Health Survey, consisting of 12,375 women and men aged 18 and older. A priori hypotheses were that ambulation, cognition, emotion, and pain would predict mortality. Cox proportional hazards regression models were applied controlling for standard determinants of health and risk factors.
Single-attribute utility scores for ambulation (hazard ratio [HR] = 0.10; 0.04–0.22), hearing (HR = 0.18; 0.06–0.57), and pain (HR = 0.53; 0.29–0.96) were statistically significantly associated with an increased risk of mortality; ambulation and hearing were predictive for the 60+ cohort.
Few studies have identified hearing or pain as risk factors for mortality. This study is innovative because it identifies specific components of HRQL that predict mortality. Further research is needed to understand better the mechanisms through which deficits in hearing and pain affect mortality risks.
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DOI: 10.1016/j.jclinepi.2012.01.003
PubMed: 22521576
PubMed Central: 3547587
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Mcfarland</name><affiliation wicri:level="1"><nlm:aff id="A5">Department of Psychiatry, Oregon Health & Science University, Portland, OR, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Oregon Health & Science University, Portland, OR</wicri:regionArea></affiliation></author><author><name sortKey="Kaplan, Mark S" sort="Kaplan, Mark S" uniqKey="Kaplan M" first="Mark S." last="Kaplan">Mark S. Kaplan</name><affiliation wicri:level="1"><nlm:aff id="A4">School of Community Health, Portland State University, Portland, OR, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Community Health, Portland State University, Portland, OR</wicri:regionArea></affiliation></author><author><name sortKey="Orpana, Heather" sort="Orpana, Heather" uniqKey="Orpana H" first="Heather" last="Orpana">Heather Orpana</name><affiliation wicri:level="1"><nlm:aff id="A6">School of Psychology, University of Ottawa, Ottawa, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>School of Psychology, University of Ottawa, Ottawa, Ontario</wicri:regionArea></affiliation></author><author><name sortKey="Eckstrom, Elizabeth" sort="Eckstrom, Elizabeth" uniqKey="Eckstrom E" first="Elizabeth" last="Eckstrom">Elizabeth Eckstrom</name><affiliation wicri:level="1"><nlm:aff id="A7">Division of General Internal Medicine & Geriatrics, Department of Medicine, Oregon Health & Science University, Portland, OR, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of General Internal Medicine & Geriatrics, Department of Medicine, Oregon Health & Science University, Portland, OR</wicri:regionArea></affiliation></author></analytic><series><title level="j">Journal of clinical epidemiology</title><idno type="ISSN">0895-4356</idno><idno type="eISSN">1878-5921</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title><p id="P1">Measures of health-related quality of life (HRQL), including the Health Utilities Index Mark 3 (HUI3) are predictive of mortality. HUI3 includes eight attributes, vision, hearing, speech, ambulation, dexterity, cognition, emotion, and pain and discomfort, with five or six levels per attribute that vary from no to severe disability. This study examined associations between individual HUI3 attributes and mortality.</p></sec><sec id="S2"><title>Study Design and Setting</title><p id="P2">Baseline data and 12 years of follow-up data from a closed longitudinal cohort study, the 1994/95 Canadian National Population Health Survey, consisting of 12,375 women and men aged 18 and older. A priori hypotheses were that ambulation, cognition, emotion, and pain would predict mortality. Cox proportional hazards regression models were applied controlling for standard determinants of health and risk factors.</p></sec><sec id="S3"><title>Results</title><p id="P3">Single-attribute utility scores for ambulation (hazard ratio [HR] = 0.10; 0.04–0.22), hearing (HR = 0.18; 0.06–0.57), and pain (HR = 0.53; 0.29–0.96) were statistically significantly associated with an increased risk of mortality; ambulation and hearing were predictive for the 60+ cohort.</p></sec><sec id="S4"><title>Conclusion</title><p id="P4">Few studies have identified hearing or pain as risk factors for mortality. This study is innovative because it identifies specific components of HRQL that predict mortality. Further research is needed to understand better the mechanisms through which deficits in hearing and pain affect mortality risks.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8801383</journal-id><journal-id journal-id-type="pubmed-jr-id">5017</journal-id><journal-id journal-id-type="nlm-ta">J Clin Epidemiol</journal-id><journal-id journal-id-type="iso-abbrev">J Clin Epidemiol</journal-id><journal-title-group><journal-title>Journal of clinical epidemiology</journal-title></journal-title-group><issn pub-type="ppub">0895-4356</issn><issn pub-type="epub">1878-5921</issn></journal-meta><article-meta><article-id pub-id-type="pmid">22521576</article-id><article-id pub-id-type="pmc">3547587</article-id><article-id pub-id-type="doi">10.1016/j.jclinepi.2012.01.003</article-id><article-id pub-id-type="manuscript">NIHMS352493</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Hearing, mobility, and pain predict mortality: a longitudinal population-based study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Feeny</surname><given-names>David</given-names></name><xref ref-type="aff" rid="A1">a</xref><xref ref-type="aff" rid="A2">b</xref><xref ref-type="aff" rid="A3">c</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Huguet</surname><given-names>Nathalie</given-names></name><xref ref-type="aff" rid="A4">d</xref></contrib><contrib contrib-type="author"><name><surname>McFarland</surname><given-names>Bentson H.</given-names></name><xref ref-type="aff" rid="A5">e</xref></contrib><contrib contrib-type="author"><name><surname>Kaplan</surname><given-names>Mark S.</given-names></name><xref ref-type="aff" rid="A4">d</xref></contrib><contrib contrib-type="author"><name><surname>Orpana</surname><given-names>Heather</given-names></name><xref ref-type="aff" rid="A6">f</xref></contrib><contrib contrib-type="author"><name><surname>Eckstrom</surname><given-names>Elizabeth</given-names></name><xref ref-type="aff" rid="A7">g</xref></contrib></contrib-group><aff id="A1"><label>a</label>Kaiser Permanente Northwest Center for Health Research, Portland, OR, USA</aff><aff id="A2"><label>b</label>Health Utilities Incorporated, Dundas, Ontario, Canada</aff><aff id="A3"><label>c</label>University of Alberta, Edmonton, Alberta, Canada</aff><aff id="A4"><label>d</label>School of Community Health, Portland State University, Portland, OR, USA</aff><aff id="A5"><label>e</label>Department of Psychiatry, Oregon Health & Science University, Portland, OR, USA</aff><aff id="A6"><label>f</label>School of Psychology, University of Ottawa, Ottawa, Ontario, Canada</aff><aff id="A7"><label>g</label>Division of General Internal Medicine & Geriatrics, Department of Medicine, Oregon Health & Science University, Portland, OR, USA</aff><author-notes><corresp id="cor1"><label>*</label>Corresponding author. David Feeny, Kaiser Permanente Northwest Center for Health Research, 1209 SW Sixth Avenue, #801, Portland, OR 97204-1030, USA. Tel.: +971-255-0187; fax: +503-335-2428. <email>dafeeny@comcast.net</email> (D. Feeny)</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>30</day><month>1</month><year>2012</year></pub-date><pub-date pub-type="epub"><day>20</day><month>4</month><year>2012</year></pub-date><pub-date pub-type="ppub"><month>7</month><year>2012</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>7</month><year>2013</year></pub-date><volume>65</volume><issue>7</issue><fpage>764</fpage><lpage>777</lpage><permissions><copyright-statement>© 2012 Elsevier Inc. All rights reserved.</copyright-statement><copyright-year>2012</copyright-year></permissions><abstract><sec id="S1"><title>Objective</title><p id="P1">Measures of health-related quality of life (HRQL), including the Health Utilities Index Mark 3 (HUI3) are predictive of mortality. HUI3 includes eight attributes, vision, hearing, speech, ambulation, dexterity, cognition, emotion, and pain and discomfort, with five or six levels per attribute that vary from no to severe disability. This study examined associations between individual HUI3 attributes and mortality.</p></sec><sec id="S2"><title>Study Design and Setting</title><p id="P2">Baseline data and 12 years of follow-up data from a closed longitudinal cohort study, the 1994/95 Canadian National Population Health Survey, consisting of 12,375 women and men aged 18 and older. A priori hypotheses were that ambulation, cognition, emotion, and pain would predict mortality. Cox proportional hazards regression models were applied controlling for standard determinants of health and risk factors.</p></sec><sec id="S3"><title>Results</title><p id="P3">Single-attribute utility scores for ambulation (hazard ratio [HR] = 0.10; 0.04–0.22), hearing (HR = 0.18; 0.06–0.57), and pain (HR = 0.53; 0.29–0.96) were statistically significantly associated with an increased risk of mortality; ambulation and hearing were predictive for the 60+ cohort.</p></sec><sec id="S4"><title>Conclusion</title><p id="P4">Few studies have identified hearing or pain as risk factors for mortality. This study is innovative because it identifies specific components of HRQL that predict mortality. Further research is needed to understand better the mechanisms through which deficits in hearing and pain affect mortality risks.</p></sec></abstract><kwd-group><kwd>Health Utilities Index Mark 3</kwd><kwd>Mortality</kwd><kwd>Predictive validity</kwd><kwd>Mortality</kwd><kwd>Longitudinal</kwd><kwd>Health-related quality of life</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Institute of Diabetes and Digestive and Kidney Diseases : NIDDK</funding-source><award-id>R21 DK080277-02 || DK</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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