The involvement of the striatum in decision making
Identifieur interne : 000134 ( Pmc/Curation ); précédent : 000133; suivant : 000135The involvement of the striatum in decision making
Auteurs : Julie Goulet-KennedySource :
- Dialogues in Clinical Neuroscience [ 1294-8322 ] ; 2016.
Abstract
Decision making has been extensively studied in the context of economics and from a group perspective, but still little is known on individual decision making. Here we discuss the different cognitive processes involved in decision making and its associated neural substrates. The putative conductors in decision making appear to be the prefrontal cortex and the striatum. Impaired decision-making skills in various clinical populations have been associated with activity in the prefrontal cortex and in the striatum. We highlight the importance of strengthening the degree of integration of both cognitive and neural substrates in order to further our understanding of decision-making skills. In terms of cognitive paradigms, there is a need to improve the ecological value of experimental tasks that assess decision making in various contexts and with rewards; this would help translate laboratory learnings into real-life benefits. In terms of neural substrates, the use of neuroimaging techniques helps characterize the neural networks associated with decision making; more recently, ways to modulate brain activity, such as in the prefrontal cortex and connected regions (eg, striatum), with noninvasive brain stimulation have also shed light on the neural and cognitive substrates of decision making. Together, these cognitive and neural approaches might be useful for patients with impaired decision-making skills. The drive behind this line of work is that decision-making abilities underlie important aspects of wellness, health, security, and financial and social choices in our daily lives.
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PubMed: 27069380
PubMed Central: 4826771
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The involvement of the striatum in decision making</title><author><name sortKey="Goulet Kennedy, Julie" sort="Goulet Kennedy, Julie" uniqKey="Goulet Kennedy J" first="Julie" last="Goulet-Kennedy">Julie Goulet-Kennedy</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27069380</idno><idno type="pmc">4826771</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826771</idno><idno type="RBID">PMC:4826771</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000134</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000134</idno><idno type="wicri:Area/Pmc/Curation">000134</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000134</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The involvement of the striatum in decision making</title><author><name sortKey="Goulet Kennedy, Julie" sort="Goulet Kennedy, Julie" uniqKey="Goulet Kennedy J" first="Julie" last="Goulet-Kennedy">Julie Goulet-Kennedy</name></author></analytic><series><title level="j">Dialogues in Clinical Neuroscience</title><idno type="ISSN">1294-8322</idno><idno type="eISSN">1958-5969</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Decision making has been extensively studied in the context of economics and from a group perspective, but still little is known on individual decision making. Here we discuss the different cognitive processes involved in decision making and its associated neural substrates. The putative conductors in decision making appear to be the prefrontal cortex and the striatum. Impaired decision-making skills in various clinical populations have been associated with activity in the prefrontal cortex and in the striatum. We highlight the importance of strengthening the degree of integration of both cognitive and neural substrates in order to further our understanding of decision-making skills. In terms of cognitive paradigms, there is a need to improve the ecological value of experimental tasks that assess decision making in various contexts and with rewards; this would help translate laboratory learnings into real-life benefits. In terms of neural substrates, the use of neuroimaging techniques helps characterize the neural networks associated with decision making; more recently, ways to modulate brain activity, such as in the prefrontal cortex and connected regions (eg, striatum), with noninvasive brain stimulation have also shed light on the neural and cognitive substrates of decision making. Together, these cognitive and neural approaches might be useful for patients with impaired decision-making skills. The drive behind this line of work is that decision-making abilities underlie important aspects of wellness, health, security, and financial and social choices in our daily lives.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Adolphs, R" uniqKey="Adolphs R">R. Adolphs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frank, Mj" uniqKey="Frank M">MJ. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Dialogues Clin Neurosci</journal-id><journal-id journal-id-type="iso-abbrev">Dialogues Clin Neurosci</journal-id><journal-id journal-id-type="pmc">Dialogues Clin Neurosci</journal-id><journal-title-group><journal-title>Dialogues in Clinical Neuroscience</journal-title></journal-title-group><issn pub-type="ppub">1294-8322</issn><issn pub-type="epub">1958-5969</issn><publisher><publisher-name>Les Laboratoires Servier</publisher-name><publisher-loc>France</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27069380</article-id><article-id pub-id-type="pmc">4826771</article-id><article-categories><subj-group subj-group-type="heading"><subject>Clinical Research</subject></subj-group></article-categories><title-group><article-title>The involvement of the striatum in decision making</article-title><trans-title-group xml:lang="es"><trans-title>La participación del estriado en la toma de decisiones</trans-title></trans-title-group><trans-title-group xml:lang="fr"><trans-title>L'implication du striatum dans la prise de décision</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Goulet-Kennedy</surname><given-names>Julie</given-names></name><degrees>BSc</degrees><aff>Centre interdisciplinaire de recherche en réadaptation et en intégration sociale. Centre de recherche de l'Institut universitaire en santé mentale de Québec; Faculté de médecine, Université Laval, Québec, Canada</aff></contrib></contrib-group><contrib-group><contrib contrib-type="author"><name><surname>Labbe</surname><given-names>Sara</given-names></name><degrees>MSc</degrees><aff>Centre interdisciplinaire de recherche en réadaptation et en intégration sociale. Centre de recherche de l'Institut universitaire en santé mentale de Québec; Faculté de médecine, Université Laval, Québec, Canada</aff></contrib></contrib-group><contrib-group><contrib contrib-type="author"><name><surname>Fecteau</surname><given-names>Shirley</given-names></name><degrees>PhD</degrees><xref ref-type="corresp" rid="COR1">*</xref><aff>Centre interdisciplinaire de recherche en réadaptation et en intégration sociale. Centre de recherche de l'Institut universitaire en santé mentale de Québec; Faculté de médecine, Université Laval, Québec, Canada</aff></contrib></contrib-group><author-notes><corresp id="COR1"><label>*</label>E-mail: <email>Shirley.fecteau@fmed.ulaval.ca</email></corresp></author-notes><pub-date pub-type="epub-ppub"><month>3</month><year>2016</year></pub-date><pmc-comment>Fake ppub date generated by PMC from publisher
pub-date/@pub-type='epub-ppub' </pmc-comment>
<pub-date pub-type="ppub"><month>3</month><year>2016</year></pub-date><volume>18</volume><issue>1</issue><fpage>55</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright: © 2016 Institut la Conférence Hippocrate - Servier Research Group</copyright-statement><copyright-year>2016</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc-nd/3.0/">http://creativecommons.org/licenses/by-nc-nd/3.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>Decision making has been extensively studied in the context of economics and from a group perspective, but still little is known on individual decision making. Here we discuss the different cognitive processes involved in decision making and its associated neural substrates. The putative conductors in decision making appear to be the prefrontal cortex and the striatum. Impaired decision-making skills in various clinical populations have been associated with activity in the prefrontal cortex and in the striatum. We highlight the importance of strengthening the degree of integration of both cognitive and neural substrates in order to further our understanding of decision-making skills. In terms of cognitive paradigms, there is a need to improve the ecological value of experimental tasks that assess decision making in various contexts and with rewards; this would help translate laboratory learnings into real-life benefits. In terms of neural substrates, the use of neuroimaging techniques helps characterize the neural networks associated with decision making; more recently, ways to modulate brain activity, such as in the prefrontal cortex and connected regions (eg, striatum), with noninvasive brain stimulation have also shed light on the neural and cognitive substrates of decision making. Together, these cognitive and neural approaches might be useful for patients with impaired decision-making skills. The drive behind this line of work is that decision-making abilities underlie important aspects of wellness, health, security, and financial and social choices in our daily lives.</p></abstract><trans-abstract xml:lang="es"><p>La toma de decisiones ha sido ampliamente estudiada en el contexto de la economía y desde una perspectiva grupal, pero aun se conoce poco acerca de la toma de decisiones individual. En este artículo se comentan los diferentes procesos cognitivos involucrados en la toma de decisiones y en sus sustratos neurales asociados. Los supuestos conductores en la toma de decisiones parecen ser la corteza prefrontal y el estriado. El deterioro en las destrezas para la toma de decisiones en varias poblaciones clínicas se ha asociado con actividad en la corteza prefrontal y en el estriado. Se destaca la importancia del fortalecimiento del grado de integración de los sustratos cognitivos y neurales con el fin de mejorar nuestra comprensión acerca de las destrezas para la toma de decisiones. En términos de paradigmas cognitivos, hay una necesidad de mejorar el valor ecológico de las tareas experimentales que evalúan la toma de decisiones en varios contextos y con recompensas; esto ayudaría a traducir los aprendizajes de laboratorio en beneficios en la vida real. En términos de los sustratos neurales, el empleo de técnicas de neuroimágenes ayuda a caracterizar las redes neurales asociadas con la toma de decisiones. Recientemente la modulación de la actividad cerebral, tanto en la corteza prefrontal como en las regiones conectadas (por ejemplo, el estriado), mediante estimulación cerebral no invasora también ha dado luces acerca de los sustratos neural y cognitivo en la toma de decisiones. A la vez, estas aproximaciones cognitivas y neurales podrían ser útiles para pacientes con deterioro en las destrezas para la toma de decisiones. El denominador común detrás de esta línea de trabajo es que las destrezas para la toma de decisiones están a la base de importantes aspectos del bienestar, la salud, la seguridad y las elecciones financieras y sociales en nuestra vida diaria.</p></trans-abstract><trans-abstract xml:lang="fr"><p>La prise de décision a été largement étudiée dans le contexte économique et du point de vue du groupe, mais la prise de décision individuelle est encore mal connue. Nous analysons ici les différents processus cognitifs impliqués dans la prise de décision et les substrats neuronaux associés. Les déclencheurs éventuels de la prise de décision se situeraient dans le cortex préfrontal et le striatum. Dans différentes populations cliniques, une altération des capacités de prise de décision s'associe à une activité du cortex préfrontal et du striatum. Nous soulignons l'importance de renforcer le degré d'intégration des substrats cognitifs et neuronaux afin de mieux comprendre les capacités de prise de décision. En termes de modèles cognitifs, il faut améliorer la valeur écologique des applications expérimentales qui évaluent la prise de décision dans différents contextes et avec des récompenses, ce qui aiderait à traduire les apprentissages expérimental en bénéfices dans la vie réelle. En termes de substrats neuronaux, la neuro-imagerie permet de caractériser les réseaux neuronaux associés à la prise de décision; plus récemment, la modulation de l'activité cérébrale, comme dans le cortex préfrontal et les régions connectées (par ex le striatum), par une stimulation cérébrale non invasive a aussi mis en lumière les substrats neuronaux et cognitifs de la prise de décision. Conjointement, ces approches cognitives et neuronales pourraient être utiles aux patients dont les capacités de prise de décision sont altérées. En fil conducteur de ce travail, l'aptitude à la prise de décision sous-tend des aspects importants du bien-être, de la santé, de la sécurité et des choix financiers et sociaux dans nos vies quotidiennes.</p></trans-abstract><kwd-group><kwd><italic>decision making</italic></kwd><kwd><italic>impulsivity</italic></kwd><kwd><italic>pathological gambling</italic></kwd><kwd><italic>prefrontal cortex</italic></kwd><kwd><italic>reward seeking</italic></kwd><kwd><italic>risk taking</italic></kwd><kwd><italic>schizophrenia</italic></kwd><kwd><italic>striatum</italic></kwd><kwd><italic>substance use disorder</italic></kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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