La maladie de Parkinson au Canada (serveur d'exploration)

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LOCATION OF ACTIVE CONTACTS IN PATIENTS WITH PRIMARY DYSTONIA TREATED WITH GLOBUS PALLIDUS DEEP BRAIN STIMULATION

Identifieur interne : 000653 ( PascalFrancis/Curation ); précédent : 000652; suivant : 000654

LOCATION OF ACTIVE CONTACTS IN PATIENTS WITH PRIMARY DYSTONIA TREATED WITH GLOBUS PALLIDUS DEEP BRAIN STIMULATION

Auteurs : Clement Hamani [Canada] ; Elena Moro [Canada] ; Cindy Zadikoff [Canada] ; Yu-Yan Poon [Canada] ; Andres M. Lozano [Canada] ; Philip A. Starr ; Julie G. Pilitsis ; Roy A. E. Bakay ; Robert G. Grossman

Source :

RBID : Pascal:08-0204731

Descripteurs français

English descriptors

Abstract

OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.
pA  
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A03   1    @0 Neurosurgery
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A08 01  1  ENG  @1 LOCATION OF ACTIVE CONTACTS IN PATIENTS WITH PRIMARY DYSTONIA TREATED WITH GLOBUS PALLIDUS DEEP BRAIN STIMULATION
A11 01  1    @1 HAMANI (Clement)
A11 02  1    @1 MORO (Elena)
A11 03  1    @1 ZADIKOFF (Cindy)
A11 04  1    @1 POON (Yu-Yan)
A11 05  1    @1 LOZANO (Andres M.)
A11 06  1    @1 STARR (Philip A.)
A11 07  1    @1 PILITSIS (Julie G.)
A11 08  1    @1 BAKAY (Roy A. E.)
A11 09  1    @1 GROSSMAN (Robert G.)
A14 01      @1 Division of Neurosurgery, Toronto Western Hospital, University of Toronto, University Health Network @2 Toronto @3 CAN @Z 1 aut. @Z 5 aut.
A14 02      @1 Movement Disorders Center, Division of Neurology, Toronto Western Hospital, University of Toronto, University Health Network @2 Toronto @3 CAN @Z 2 aut. @Z 3 aut. @Z 4 aut.
A20       @1 217-225
A21       @1 2008
A23 01      @0 ENG
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A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
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C01 01    ENG  @0 OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.
C02 01  X    @0 002B25J
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C03 01  X  SPA  @0 Distonía @5 01
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C03 05  X  FRE  @0 Encéphale @5 11
C03 05  X  ENG  @0 Encephalon @5 11
C03 05  X  SPA  @0 Encéfalo @5 11
C03 06  X  FRE  @0 Chirurgie @5 12
C03 06  X  ENG  @0 Surgery @5 12
C03 06  X  SPA  @0 Cirugía @5 12
C07 01  X  FRE  @0 Syndrome extrapyramidal @5 37
C07 01  X  ENG  @0 Extrapyramidal syndrome @5 37
C07 01  X  SPA  @0 Extrapiramidal síndrome @5 37
C07 02  X  FRE  @0 Mouvement involontaire @5 38
C07 02  X  ENG  @0 Involuntary movement @5 38
C07 02  X  SPA  @0 Movimiento involuntario @5 38
C07 03  X  FRE  @0 Pathologie du muscle strié @5 39
C07 03  X  ENG  @0 Striated muscle disease @5 39
C07 03  X  SPA  @0 Músculo estriado patología @5 39
C07 04  X  FRE  @0 Trouble neurologique @5 41
C07 04  X  ENG  @0 Neurological disorder @5 41
C07 04  X  SPA  @0 Trastorno neurológico @5 41
C07 05  X  FRE  @0 Pathologie de l'encéphale @5 42
C07 05  X  ENG  @0 Cerebral disorder @5 42
C07 05  X  SPA  @0 Encéfalo patología @5 42
C07 06  X  FRE  @0 Pathologie du système nerveux central @5 43
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C07 06  X  SPA  @0 Sistema nervosio central patología @5 43
N21       @1 133
N44 01      @1 OTO
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<div type="abstract" xml:lang="en">OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.</div>
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<s0>OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.</s0>
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<fC03 i1="04" i2="X" l="FRE">
<s0>Traitement</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Treatment</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>10</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Encéphale</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Encephalon</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Encéfalo</s0>
<s5>11</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Chirurgie</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Surgery</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Cirugía</s0>
<s5>12</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Syndrome extrapyramidal</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Mouvement involontaire</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Involuntary movement</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Movimiento involuntario</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Pathologie du muscle strié</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Striated muscle disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Músculo estriado patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Trouble neurologique</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Neurological disorder</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Trastorno neurológico</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Pathologie de l'encéphale</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Pathologie du système nerveux central</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>43</s5>
</fC07>
<fN21>
<s1>133</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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