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LOCATION OF ACTIVE CONTACTS IN PATIENTS WITH PRIMARY DYSTONIA TREATED WITH GLOBUS PALLIDUS DEEP BRAIN STIMULATION

Identifieur interne : 000657 ( PascalFrancis/Corpus ); précédent : 000656; suivant : 000658

LOCATION OF ACTIVE CONTACTS IN PATIENTS WITH PRIMARY DYSTONIA TREATED WITH GLOBUS PALLIDUS DEEP BRAIN STIMULATION

Auteurs : Clement Hamani ; Elena Moro ; Cindy Zadikoff ; Yu-Yan Poon ; Andres M. Lozano ; Philip A. Starr ; Julie G. Pilitsis ; Roy A. E. Bakay ; Robert G. Grossman

Source :

RBID : Pascal:08-0204731

Descripteurs français

English descriptors

Abstract

OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A01 01  1    @0 0148-396X
A02 01      @0 NRSRDY
A03   1    @0 Neurosurgery
A05       @2 62
A06       @2 3 @3 SUP
A08 01  1  ENG  @1 LOCATION OF ACTIVE CONTACTS IN PATIENTS WITH PRIMARY DYSTONIA TREATED WITH GLOBUS PALLIDUS DEEP BRAIN STIMULATION
A11 01  1    @1 HAMANI (Clement)
A11 02  1    @1 MORO (Elena)
A11 03  1    @1 ZADIKOFF (Cindy)
A11 04  1    @1 POON (Yu-Yan)
A11 05  1    @1 LOZANO (Andres M.)
A11 06  1    @1 STARR (Philip A.)
A11 07  1    @1 PILITSIS (Julie G.)
A11 08  1    @1 BAKAY (Roy A. E.)
A11 09  1    @1 GROSSMAN (Robert G.)
A14 01      @1 Division of Neurosurgery, Toronto Western Hospital, University of Toronto, University Health Network @2 Toronto @3 CAN @Z 1 aut. @Z 5 aut.
A14 02      @1 Movement Disorders Center, Division of Neurology, Toronto Western Hospital, University of Toronto, University Health Network @2 Toronto @3 CAN @Z 2 aut. @Z 3 aut. @Z 4 aut.
A20       @1 217-225
A21       @1 2008
A23 01      @0 ENG
A43 01      @1 INIST @2 18396 @5 354000183372470300
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
A45       @0 40 ref.
A47 01  1    @0 08-0204731
A60       @1 P @3 AR @3 CT
A61       @0 A
A64 01  1    @0 Neurosurgery
A66 01      @0 USA
C01 01    ENG  @0 OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.
C02 01  X    @0 002B25J
C03 01  X  FRE  @0 Dystonie @5 01
C03 01  X  ENG  @0 Dystonia @5 01
C03 01  X  SPA  @0 Distonía @5 01
C03 02  X  FRE  @0 Pathologie du système nerveux @5 02
C03 02  X  ENG  @0 Nervous system diseases @5 02
C03 02  X  SPA  @0 Sistema nervioso patología @5 02
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C03 03  X  ENG  @0 Human @5 09
C03 03  X  SPA  @0 Hombre @5 09
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C03 05  X  FRE  @0 Encéphale @5 11
C03 05  X  ENG  @0 Encephalon @5 11
C03 05  X  SPA  @0 Encéfalo @5 11
C03 06  X  FRE  @0 Chirurgie @5 12
C03 06  X  ENG  @0 Surgery @5 12
C03 06  X  SPA  @0 Cirugía @5 12
C07 01  X  FRE  @0 Syndrome extrapyramidal @5 37
C07 01  X  ENG  @0 Extrapyramidal syndrome @5 37
C07 01  X  SPA  @0 Extrapiramidal síndrome @5 37
C07 02  X  FRE  @0 Mouvement involontaire @5 38
C07 02  X  ENG  @0 Involuntary movement @5 38
C07 02  X  SPA  @0 Movimiento involuntario @5 38
C07 03  X  FRE  @0 Pathologie du muscle strié @5 39
C07 03  X  ENG  @0 Striated muscle disease @5 39
C07 03  X  SPA  @0 Músculo estriado patología @5 39
C07 04  X  FRE  @0 Trouble neurologique @5 41
C07 04  X  ENG  @0 Neurological disorder @5 41
C07 04  X  SPA  @0 Trastorno neurológico @5 41
C07 05  X  FRE  @0 Pathologie de l'encéphale @5 42
C07 05  X  ENG  @0 Cerebral disorder @5 42
C07 05  X  SPA  @0 Encéfalo patología @5 42
C07 06  X  FRE  @0 Pathologie du système nerveux central @5 43
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Format Inist (serveur)

NO : PASCAL 08-0204731 INIST
ET : LOCATION OF ACTIVE CONTACTS IN PATIENTS WITH PRIMARY DYSTONIA TREATED WITH GLOBUS PALLIDUS DEEP BRAIN STIMULATION
AU : HAMANI (Clement); MORO (Elena); ZADIKOFF (Cindy); POON (Yu-Yan); LOZANO (Andres M.); STARR (Philip A.); PILITSIS (Julie G.); BAKAY (Roy A. E.); GROSSMAN (Robert G.)
AF : Division of Neurosurgery, Toronto Western Hospital, University of Toronto, University Health Network/Toronto/Canada (1 aut., 5 aut.); Movement Disorders Center, Division of Neurology, Toronto Western Hospital, University of Toronto, University Health Network/Toronto/Canada (2 aut., 3 aut., 4 aut.)
DT : Publication en série; Article; Commentaire; Niveau analytique
SO : Neurosurgery; ISSN 0148-396X; Coden NRSRDY; Etats-Unis; Da. 2008; Vol. 62; No. 3 SUP; Pp. 217-225; Bibl. 40 ref.
LA : Anglais
EA : OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.
CC : 002B25J
FD : Dystonie; Pathologie du système nerveux; Homme; Traitement; Encéphale; Chirurgie
FG : Syndrome extrapyramidal; Mouvement involontaire; Pathologie du muscle strié; Trouble neurologique; Pathologie de l'encéphale; Pathologie du système nerveux central
ED : Dystonia; Nervous system diseases; Human; Treatment; Encephalon; Surgery
EG : Extrapyramidal syndrome; Involuntary movement; Striated muscle disease; Neurological disorder; Cerebral disorder; Central nervous system disease
SD : Distonía; Sistema nervioso patología; Hombre; Tratamiento; Encéfalo; Cirugía
LO : INIST-18396.354000183372470300
ID : 08-0204731

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Pascal:08-0204731

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<div type="abstract" xml:lang="en">OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.</div>
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<s0>OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.</s0>
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<s5>42</s5>
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<s0>Cerebral disorder</s0>
<s5>42</s5>
</fC07>
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<s5>42</s5>
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<s5>43</s5>
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<s5>43</s5>
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<NO>PASCAL 08-0204731 INIST</NO>
<ET>LOCATION OF ACTIVE CONTACTS IN PATIENTS WITH PRIMARY DYSTONIA TREATED WITH GLOBUS PALLIDUS DEEP BRAIN STIMULATION</ET>
<AU>HAMANI (Clement); MORO (Elena); ZADIKOFF (Cindy); POON (Yu-Yan); LOZANO (Andres M.); STARR (Philip A.); PILITSIS (Julie G.); BAKAY (Roy A. E.); GROSSMAN (Robert G.)</AU>
<AF>Division of Neurosurgery, Toronto Western Hospital, University of Toronto, University Health Network/Toronto/Canada (1 aut., 5 aut.); Movement Disorders Center, Division of Neurology, Toronto Western Hospital, University of Toronto, University Health Network/Toronto/Canada (2 aut., 3 aut., 4 aut.)</AF>
<DT>Publication en série; Article; Commentaire; Niveau analytique</DT>
<SO>Neurosurgery; ISSN 0148-396X; Coden NRSRDY; Etats-Unis; Da. 2008; Vol. 62; No. 3 SUP; Pp. 217-225; Bibl. 40 ref.</SO>
<LA>Anglais</LA>
<EA>OBJECTIVE: Deep brain stimulation of the globus pallidus internus has been used for the treatment of various forms of dystonia, but the factors influencing postoperative outcomes remain unknown. We compared the location of the contacts being used for stimulation (active contacts) in patients with cervical dystonia, generalized dystonia, and Parkinson's disease and correlated the results with clinical outcome. METHODS: Postoperative magnetic resonance scans of 13 patients with cervical dystonia, six patients with generalized dystonia, and five with Parkinson's disease who underwent globus pallidus internus deep brain stimulation were analyzed. We assessed the location of the active contacts relative to the midcommisural point and in relation to the anteroposterior and mediolateral boundaries of the pallidum. Postoperative outcome was measured with the Toronto. Western Spasmodic Torticollis Rating Scale (for cervical dystonia) and the Burke-Fahn-Marsden Dystonia Rating Scale (for genealized dystonia) during the last follow-up. RESULTS: We found that the location of the active contacts relative to the midcommisural point and the internal boundaries of the-pallidum was similar across the groups. In our series, the contacts used for stimulation were clustered in the posterolateral region of the pallidum. Within that region, we found no correlation between the location of the contacts and postoperative outcome. CONCLUSION: The location of the active contacts used for globus pallidus internus deep brain stimulation was similar in patients with cervical dystonia, generalized dystonia, and Parkinson's disease.</EA>
<CC>002B25J</CC>
<FD>Dystonie; Pathologie du système nerveux; Homme; Traitement; Encéphale; Chirurgie</FD>
<FG>Syndrome extrapyramidal; Mouvement involontaire; Pathologie du muscle strié; Trouble neurologique; Pathologie de l'encéphale; Pathologie du système nerveux central</FG>
<ED>Dystonia; Nervous system diseases; Human; Treatment; Encephalon; Surgery</ED>
<EG>Extrapyramidal syndrome; Involuntary movement; Striated muscle disease; Neurological disorder; Cerebral disorder; Central nervous system disease</EG>
<SD>Distonía; Sistema nervioso patología; Hombre; Tratamiento; Encéfalo; Cirugía</SD>
<LO>INIST-18396.354000183372470300</LO>
<ID>08-0204731</ID>
</server>
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