La maladie de Parkinson au Canada (serveur d'exploration)

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Surgery for levodopa-induced dyskinesias. Discussion

Identifieur interne : 000020 ( PascalFrancis/Curation ); précédent : 000019; suivant : 000021

Surgery for levodopa-induced dyskinesias. Discussion

Auteurs : A. E. Lang [Canada] ; LANGSTON ; RASCOL ; BROTCHIE ; BENABID ; MELAMED ; BONUCELLI ; OLANOW ; OBESO ; GIMENEZ-ROLDAN ; RAJPUT ; FAHN ; NUTT ; BROOKS ; CHASE

Source :

RBID : Pascal:00-0262068

Descripteurs français

English descriptors

Abstract

The effects of surgical interventions for levodopa-induced dyskinesias (LIDs) in Parkinson's disease are reviewed. Since the introduction of levodopa, thalamotomy has been reported to have variable effects on LIDs. Striking benefit has been demonstrated, and efficacy is probably dependent on the size and location of the lesion. However, it remains unclear whether it is an effective treatment for all types of LIDs. Currently, pallidotomy is probably the most reliable and effective surgical treatment for LIDs, and will continue to play an important role in its management until other treatments become more widely available. Deep brain stimulation is an extremely exciting mode of therapy, particularly in the subthalamic nucleus and the globus pallidus, and early results of its use in the treatment of LIDs are promising. The effects of cerebral transplantation, still an experimental technique, on LIDs are inconsistent and controversial, and there is little reliable evidence that gamma knife radiosurgery can be safely applied to parkinsonian patients for the treatment of LIDs.
pA  
A01 01  1    @0 0364-5134
A02 01      @0 ANNED3
A03   1    @0 Ann. neurol.
A05       @2 47
A06       @2 4 @3 SUP1
A08 01  1  ENG  @1 Surgery for levodopa-induced dyskinesias. Discussion
A09 01  1  ENG  @1 Levodopa-induced dyskinesias
A11 01  1    @1 LANG (A. E.)
A11 02  1    @1 LANGSTON @9 comment.
A11 03  1    @1 RASCOL @9 comment.
A11 04  1    @1 BROTCHIE @9 comment.
A11 05  1    @1 BENABID @9 comment.
A11 06  1    @1 MELAMED @9 comment.
A11 07  1    @1 BONUCELLI @9 comment.
A11 08  1    @1 OLANOW @9 comment.
A11 09  1    @1 OBESO @9 comment.
A11 10  1    @1 GIMENEZ-ROLDAN @9 comment.
A11 11  1    @1 RAJPUT @9 comment.
A11 12  1    @1 FAHN @9 comment.
A11 13  1    @1 NUTT @9 comment.
A11 14  1    @1 BROOKS @9 comment.
A11 15  1    @1 CHASE @9 comment.
A12 01  1    @1 OLANOW (C. Warren) @9 ed.
A14 01      @1 Toronto Western Hospital, Morton & Gloria Shulman Movement Disorders Clinic; and the University of Toronto @2 Ontario @3 CAN @Z 1 aut.
A15 01      @1 Department of Neurology, Mount Sinai School of Medicine, 1 Gustave Levy Place, Annenburg 14-94 @2 New York, NY 10029 @3 USA @Z 1 aut.
A20       @2 S193-S202
A21       @1 2000
A23 01      @0 ENG
A43 01      @1 INIST @2 16555 @5 354000082146950220
A44       @0 0000 @1 © 2000 INIST-CNRS. All rights reserved.
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A47 01  1    @0 00-0262068
A60       @1 P @3 AR @3 CT
A61       @0 A
A64 01  1    @0 Annals of neurology
A66 01      @0 USA
C01 01    ENG  @0 The effects of surgical interventions for levodopa-induced dyskinesias (LIDs) in Parkinson's disease are reviewed. Since the introduction of levodopa, thalamotomy has been reported to have variable effects on LIDs. Striking benefit has been demonstrated, and efficacy is probably dependent on the size and location of the lesion. However, it remains unclear whether it is an effective treatment for all types of LIDs. Currently, pallidotomy is probably the most reliable and effective surgical treatment for LIDs, and will continue to play an important role in its management until other treatments become more widely available. Deep brain stimulation is an extremely exciting mode of therapy, particularly in the subthalamic nucleus and the globus pallidus, and early results of its use in the treatment of LIDs are promising. The effects of cerebral transplantation, still an experimental technique, on LIDs are inconsistent and controversial, and there is little reliable evidence that gamma knife radiosurgery can be safely applied to parkinsonian patients for the treatment of LIDs.
C02 01  X    @0 002B17G
C03 01  X  FRE  @0 Parkinson maladie @5 01
C03 01  X  ENG  @0 Parkinson disease @5 01
C03 01  X  SPA  @0 Parkinson enfermedad @5 01
C03 02  X  FRE  @0 Dyskinésie @5 04
C03 02  X  ENG  @0 Dyskinesia @5 04
C03 02  X  SPA  @0 Disquinesia @5 04
C03 03  X  FRE  @0 Lévodopa @5 07
C03 03  X  ENG  @0 Levodopa @5 07
C03 03  X  SPA  @0 Levodopa @5 07
C03 04  X  FRE  @0 Antiparkinsonien @5 08
C03 04  X  ENG  @0 Antiparkinson agent @5 08
C03 04  X  SPA  @0 Antiparkinsoniano @5 08
C03 05  X  FRE  @0 Chirurgie @5 10
C03 05  X  ENG  @0 Surgery @5 10
C03 05  X  SPA  @0 Cirugía @5 10
C03 06  X  FRE  @0 Article synthèse @5 16
C03 06  X  ENG  @0 Review @5 16
C03 06  X  SPA  @0 Artículo síntesis @5 16
C03 07  X  FRE  @0 Traitement @5 17
C03 07  X  ENG  @0 Treatment @5 17
C03 07  X  SPA  @0 Tratamiento @5 17
C03 08  X  FRE  @0 Homme @5 20
C03 08  X  ENG  @0 Human @5 20
C03 08  X  SPA  @0 Hombre @5 20
C03 09  X  FRE  @0 Thalamotomie @5 23
C03 09  X  ENG  @0 Thalamotomy @5 23
C03 09  X  SPA  @0 Talamotomía @5 23
C03 10  X  FRE  @0 Pallidum @5 24
C03 10  X  ENG  @0 Pallidum @5 24
C03 10  X  SPA  @0 Pallidum @5 24
C03 11  X  FRE  @0 Transplantation @5 35
C03 11  X  ENG  @0 Transplantation @5 35
C03 11  X  SPA  @0 Trasplantación @5 35
C07 01  X  FRE  @0 Système nerveux pathologie @5 37
C07 01  X  ENG  @0 Nervous system diseases @5 37
C07 01  X  SPA  @0 Sistema nervioso patología @5 37
C07 02  X  FRE  @0 Système nerveux central pathologie @5 38
C07 02  X  ENG  @0 Central nervous system disease @5 38
C07 02  X  SPA  @0 Sistema nervosio central patología @5 38
C07 03  X  FRE  @0 Encéphale pathologie @5 39
C07 03  X  ENG  @0 Cerebral disorder @5 39
C07 03  X  SPA  @0 Encéfalo patología @5 39
C07 04  X  FRE  @0 Extrapyramidal syndrome @5 40
C07 04  X  ENG  @0 Extrapyramidal syndrome @5 40
C07 04  X  SPA  @0 Extrapiramidal síndrome @5 40
C07 05  X  FRE  @0 Maladie dégénérative @5 41
C07 05  X  ENG  @0 Degenerative disease @5 41
C07 05  X  SPA  @0 Enfermedad degenerativa @5 41
C07 06  X  FRE  @0 Trouble neurologique @5 46
C07 06  X  ENG  @0 Neurological disorder @5 46
C07 06  X  SPA  @0 Trastorno neurológico @5 46
C07 07  X  FRE  @0 Mouvement involontaire @5 47
C07 07  X  ENG  @0 Involuntary movement @5 47
C07 07  X  SPA  @0 Movimiento involuntario @5 47
N21       @1 178

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Le document en format XML

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<div type="abstract" xml:lang="en">The effects of surgical interventions for levodopa-induced dyskinesias (LIDs) in Parkinson's disease are reviewed. Since the introduction of levodopa, thalamotomy has been reported to have variable effects on LIDs. Striking benefit has been demonstrated, and efficacy is probably dependent on the size and location of the lesion. However, it remains unclear whether it is an effective treatment for all types of LIDs. Currently, pallidotomy is probably the most reliable and effective surgical treatment for LIDs, and will continue to play an important role in its management until other treatments become more widely available. Deep brain stimulation is an extremely exciting mode of therapy, particularly in the subthalamic nucleus and the globus pallidus, and early results of its use in the treatment of LIDs are promising. The effects of cerebral transplantation, still an experimental technique, on LIDs are inconsistent and controversial, and there is little reliable evidence that gamma knife radiosurgery can be safely applied to parkinsonian patients for the treatment of LIDs.</div>
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<s0>Review</s0>
<s5>16</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Artículo síntesis</s0>
<s5>16</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Traitement</s0>
<s5>17</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Treatment</s0>
<s5>17</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Tratamiento</s0>
<s5>17</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Homme</s0>
<s5>20</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Human</s0>
<s5>20</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Hombre</s0>
<s5>20</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Thalamotomie</s0>
<s5>23</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Thalamotomy</s0>
<s5>23</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Talamotomía</s0>
<s5>23</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE">
<s0>Pallidum</s0>
<s5>24</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG">
<s0>Pallidum</s0>
<s5>24</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA">
<s0>Pallidum</s0>
<s5>24</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE">
<s0>Transplantation</s0>
<s5>35</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG">
<s0>Transplantation</s0>
<s5>35</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA">
<s0>Trasplantación</s0>
<s5>35</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Système nerveux pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Nervous system diseases</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Sistema nervioso patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Système nerveux central pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Encéphale pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Trouble neurologique</s0>
<s5>46</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Neurological disorder</s0>
<s5>46</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Trastorno neurológico</s0>
<s5>46</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE">
<s0>Mouvement involontaire</s0>
<s5>47</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG">
<s0>Involuntary movement</s0>
<s5>47</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA">
<s0>Movimiento involuntario</s0>
<s5>47</s5>
</fC07>
<fN21>
<s1>178</s1>
</fN21>
</pA>
</standard>
</inist>
</record>

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