Pathological gambling in patients with Parkinson's disease is associated with fronto-striatal disconnection: a path modeling analysis.
Identifieur interne : 000E18 ( Ncbi/Curation ); précédent : 000E17; suivant : 000E19Pathological gambling in patients with Parkinson's disease is associated with fronto-striatal disconnection: a path modeling analysis.
Auteurs : Roberto Cilia [Canada] ; Sang Soo Cho ; Thilo Van Eimeren ; Giorgio Marotta ; Chiara Siri ; Ji Hyun Ko ; Giovanna Pellecchia ; Gianni Pezzoli ; Angelo Antonini ; Antonio P. StrafellaSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2011.
English descriptors
- KwdEn :
- Aged, Analysis of Variance, Brain Mapping, Corpus Striatum (diagnostic imaging), Corpus Striatum (physiopathology), Female, Gambling (complications), Gambling (diagnostic imaging), Gambling (physiopathology), Humans, Image Processing, Computer-Assisted, Male, Middle Aged, Neural Pathways (diagnostic imaging), Neural Pathways (physiopathology), Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (diagnostic imaging), Parkinson Disease (physiopathology), Prefrontal Cortex (diagnostic imaging), Prefrontal Cortex (physiopathology), Tomography, Emission-Computed, Single-Photon.
- MESH :
- complications : Gambling, Parkinson Disease.
- diagnostic imaging : Corpus Striatum, Gambling, Neural Pathways, Parkinson Disease, Prefrontal Cortex.
- physiopathology : Corpus Striatum, Gambling, Neural Pathways, Parkinson Disease, Prefrontal Cortex.
- Aged, Analysis of Variance, Brain Mapping, Female, Humans, Image Processing, Computer-Assisted, Male, Middle Aged, Neuropsychological Tests, Tomography, Emission-Computed, Single-Photon.
Abstract
Pathological gambling may occur in Parkinson's disease (PD) as a complication of dopaminergic therapy. Neuroimaging studies have suggested an abnormal dopamine transmission within the reward system, but the changes in the neural network characterizing PD patients with pathological gambling have never been investigated.
DOI: 10.1002/mds.23480
PubMed: 21284039
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pubmed:21284039Le document en format XML
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<front><div type="abstract" xml:lang="en">Pathological gambling may occur in Parkinson's disease (PD) as a complication of dopaminergic therapy. Neuroimaging studies have suggested an abnormal dopamine transmission within the reward system, but the changes in the neural network characterizing PD patients with pathological gambling have never been investigated.</div>
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