Ghrelin prevents levodopa‐induced inhibition of gastric emptying and increases circulating levodopa in fasted rats
Identifieur interne : 001423 ( Main/Exploration ); précédent : 001422; suivant : 001424Ghrelin prevents levodopa‐induced inhibition of gastric emptying and increases circulating levodopa in fasted rats
Auteurs : L. Wang [États-Unis] ; N. P. Murphy [États-Unis] ; A. Stengel [États-Unis] ; M. Goebel-Stengel [États-Unis] ; D. H. St Pierre [Canada] ; N. T. Maidment [États-Unis] ; Y. Taché [États-Unis]Source :
- Neurogastroenterology & Motility [ 1350-1925 ] ; 2012-05.
English descriptors
- KwdEn :
Abstract
Background Levodopa (l‐dopa) is the most commonly used treatment for alleviating symptoms of Parkinson’s disease. However, l‐dopa delays gastric emptying, which dampens its absorption. We investigated whether ghrelin prevents l‐dopa action on gastric emptying and enhances circulating l‐dopa in rats.
Url:
- https://api-v5.istex.fr/document/FB9D6C785585B32C6CCF9C1E614C46AF97A58199/fulltext/pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345891
DOI: 10.1111/j.1365-2982.2012.01904.x
Affiliations:
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