La maladie de Parkinson au Canada (serveur d'exploration)

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Population‐specific frequencies for LRRK2 susceptibility variants in the genetic epidemiology of Parkinson's disease (GEO‐PD) consortium

Identifieur interne : 001517 ( Istex/Curation ); précédent : 001516; suivant : 001518

Population‐specific frequencies for LRRK2 susceptibility variants in the genetic epidemiology of Parkinson's disease (GEO‐PD) consortium

Auteurs : Michael G. Heckman [États-Unis] ; Alexandra I. Soto-Ortolaza [États-Unis] ; Jan O. Aasly [Norvège] ; Nadine Abahuni [Allemagne] ; Grazia Annesi [Italie] ; Justin A. Bacon [États-Unis] ; Soraya Bardien [Afrique du Sud] ; Maria Bozi [Grèce] ; Alexis Brice [France] ; Laura Brighina [Italie] ; Jonathan Carr [Afrique du Sud] ; Marie-Christine Chartier-Harlin [France] ; Efthimios Dardiotis [Grèce] ; Dennis W. Dickson [États-Unis] ; Nancy N. Diehl [États-Unis] ; Alexis Elbaz [France] ; Carlo Ferrarese [Italie] ; Brian Fiske [États-Unis] ; J. Mark Gibson [Irlande (pays)] ; Rachel Gibson [Royaume-Uni] ; Georgios M. Hadjigeorgiou [Grèce] ; Nobutaka Hattori [Japon] ; John P. A. Ioannidis [Grèce, États-Unis] ; Magdalena Boczarska-Jedynak [Pologne] ; Barbara Jasinska-Myga [Pologne] ; Beom S. Jeon [Corée du Sud] ; Yun Joong Kim [Corée du Sud] ; Christine Klein [Allemagne] ; Rejko Kruger [Allemagne] ; Elli Kyratzi [Grèce] ; Suzanne Lesage [France] ; Chin-Hsien Lin [Taïwan] ; Timothy Lynch [Irlande (pays)] ; Demetrius M. Maraganore [États-Unis] ; George D. Mellick [Australie] ; Eugénie Mutez [France] ; Christer Nilsson [Suède] ; Grzegorz Opala [Pologne] ; Sung Sup Park [Corée du Sud] ; Simona Petrucci [Italie] ; Andreas Puschmann [Suède] ; Aldo Quattrone [Italie] ; Manu Sharma [Allemagne] ; Peter A. Silburn [Australie] ; Young Ho Sohn [Corée du Sud] ; Leonidas Stefanis [Grèce] ; Vera Tadic [Allemagne] ; Jessie Theuns [Belgique] ; Hiroyuki Tomiyama [Japon] ; Ryan J. Uitti [États-Unis] ; Enza Maria Valente [Italie] ; Christine Van Broeckhoven [Belgique] ; Simone Van De Loo [Allemagne] ; Demetrios K. Vassilatis [Grèce] ; Carles Vilari O-Güell [Canada] ; Linda R. White [Norvège] ; Karin Wirdefeldt [Suède] ; Zbigniew K. Wszolek [États-Unis] ; Ruey-Meei Wu [Taïwan] ; Faycal Hentati [Tunisie] ; Matthew J. Farrer [Canada] ; Owen A. Ross [États-Unis]

Source :

RBID : ISTEX:C6C03F04C791F2BAFA0887DE4DFC20A9DAE7F705

Abstract

Variants within the leucine‐rich repeat kinase 2 gene are recognized as the most frequent genetic cause of Parkinson's disease. Leucine‐rich repeat kinase 2 variation related to disease susceptibility displays many features that reflect the nature of complex, late‐onset sporadic disorders like Parkinson's disease.

Url:
DOI: 10.1002/mds.25600

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ISTEX:C6C03F04C791F2BAFA0887DE4DFC20A9DAE7F705

Le document en format XML

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<name sortKey="Van Broeckhoven, Christine" sort="Van Broeckhoven, Christine" uniqKey="Van Broeckhoven C" first="Christine" last="Van Broeckhoven">Christine Van Broeckhoven</name>
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<mods:affiliation>Department of Neurology, Goethe University, Frankfurt am Main, Germany</mods:affiliation>
<country xml:lang="fr">Allemagne</country>
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<title level="a" type="main" xml:lang="en">Population‐specific frequencies for LRRK2 susceptibility variants in the genetic epidemiology of Parkinson's disease (GEO‐PD) consortium</title>
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<name sortKey="Dardiotis, Efthimios" sort="Dardiotis, Efthimios" uniqKey="Dardiotis E" first="Efthimios" last="Dardiotis">Efthimios Dardiotis</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Laboratory of Neurogenetics, Faculty of Medicine, University of Thessaly, Larissa, Greece</mods:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Neurology, Laboratory of Neurogenetics, Faculty of Medicine, University of Thessaly, Larissa</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Institute of Biomedical Research and Technology, Center for Research and Technology‐Thessaly, Larissa, Greece</mods:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Institute of Biomedical Research and Technology, Center for Research and Technology‐Thessaly, Larissa</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Dickson, Dennis W" sort="Dickson, Dennis W" uniqKey="Dickson D" first="Dennis W." last="Dickson">Dennis W. Dickson</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neuroscience, Mayo Clinic, Florida, Jacksonville, USA</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neuroscience, Mayo Clinic, Florida, Jacksonville</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Diehl, Nancy N" sort="Diehl, Nancy N" uniqKey="Diehl N" first="Nancy N." last="Diehl">Nancy N. Diehl</name>
<affiliation wicri:level="1">
<mods:affiliation>Biostatistics Unit, Mayo Clinic, Florida, Jacksonville, USA</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Biostatistics Unit, Mayo Clinic, Florida, Jacksonville</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Elbaz, Alexis" sort="Elbaz, Alexis" uniqKey="Elbaz A" first="Alexis" last="Elbaz">Alexis Elbaz</name>
<affiliation wicri:level="1">
<mods:affiliation>Institut National de la Santé et de la Recherche Médicale, Unit 1018, Centre for Research in Epidemiology and Population Health, Villejuif, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Santé et de la Recherche Médicale, Unit 1018, Centre for Research in Epidemiology and Population Health, Villejuif</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Université de Versailles Saint‐Quentin, Medical Research Unit 1018, Versailles, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université de Versailles Saint‐Quentin, Medical Research Unit 1018, Versailles</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Ferrarese, Carlo" sort="Ferrarese, Carlo" uniqKey="Ferrarese C" first="Carlo" last="Ferrarese">Carlo Ferrarese</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neuroscience‐Section of Neurology, University of Milano‐Bicocca, San Gerardo Hospital, Monza, Italy</mods:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Neuroscience‐Section of Neurology, University of Milano‐Bicocca, San Gerardo Hospital, Monza</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Fiske, Brian" sort="Fiske, Brian" uniqKey="Fiske B" first="Brian" last="Fiske">Brian Fiske</name>
<affiliation wicri:level="1">
<mods:affiliation>The Michael J. Fox Foundation for Parkinson's Research, New York, New York, USA</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The Michael J. Fox Foundation for Parkinson's Research, New York, New York</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Gibson, J Mark" sort="Gibson, J Mark" uniqKey="Gibson J" first="J. Mark" last="Gibson">J. Mark Gibson</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Royal Victoria Hospital, Belfast, Ireland</mods:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Department of Neurology, Royal Victoria Hospital, Belfast</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Gibson, Rachel" sort="Gibson, Rachel" uniqKey="Gibson R" first="Rachel" last="Gibson">Rachel Gibson</name>
<affiliation wicri:level="1">
<mods:affiliation>Research and Development, GlaxoSmithKline Pharmaceuticals Ltd, Stevenage, United Kingdom</mods:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Research and Development, GlaxoSmithKline Pharmaceuticals Ltd, Stevenage</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Hadjigeorgiou, Georgios M" sort="Hadjigeorgiou, Georgios M" uniqKey="Hadjigeorgiou G" first="Georgios M." last="Hadjigeorgiou">Georgios M. Hadjigeorgiou</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Laboratory of Neurogenetics, Faculty of Medicine, University of Thessaly, Larissa, Greece</mods:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Neurology, Laboratory of Neurogenetics, Faculty of Medicine, University of Thessaly, Larissa</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Institute of Biomedical Research and Technology, Center for Research and Technology‐Thessaly, Larissa, Greece</mods:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Institute of Biomedical Research and Technology, Center for Research and Technology‐Thessaly, Larissa</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Hattori, Nobutaka" sort="Hattori, Nobutaka" uniqKey="Hattori N" first="Nobutaka" last="Hattori">Nobutaka Hattori</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Juntendo University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Ioannidis, John P A" sort="Ioannidis, John P A" uniqKey="Ioannidis J" first="John P. A." last="Ioannidis">John P. A. Ioannidis</name>
<affiliation wicri:level="1">
<mods:affiliation>Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece</mods:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Stanford Prevention Research Center, Stanford University School of Medicine, California, Stanford, USA</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Stanford Prevention Research Center, Stanford University School of Medicine, California, Stanford</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Boczarska Edynak, Magdalena" sort="Boczarska Edynak, Magdalena" uniqKey="Boczarska Edynak M" first="Magdalena" last="Boczarska-Jedynak">Magdalena Boczarska-Jedynak</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Medical University of Silesia, Katowice, Poland</mods:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Neurology, Medical University of Silesia, Katowice</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Jasinska Yga, Barbara" sort="Jasinska Yga, Barbara" uniqKey="Jasinska Yga B" first="Barbara" last="Jasinska-Myga">Barbara Jasinska-Myga</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Medical University of Silesia, Katowice, Poland</mods:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Neurology, Medical University of Silesia, Katowice</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Jeon, Beom S" sort="Jeon, Beom S" uniqKey="Jeon B" first="Beom S." last="Jeon">Beom S. Jeon</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Seoul National University Hospital, Seoul, South Korea</mods:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Neurology, Seoul National University Hospital, Seoul</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Kim, Yun Joong" sort="Kim, Yun Joong" uniqKey="Kim Y" first="Yun Joong" last="Kim">Yun Joong Kim</name>
<affiliation wicri:level="1">
<mods:affiliation>ILSONG Institute of Life Science and Department of Neurology, Hallym University, Anyang, South Korea</mods:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>ILSONG Institute of Life Science and Department of Neurology, Hallym University, Anyang</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Klein, Christine" sort="Klein, Christine" uniqKey="Klein C" first="Christine" last="Klein">Christine Klein</name>
<affiliation wicri:level="1">
<mods:affiliation>Section of Clinical and Molecular Neurogenetics at the Department of Neurology, University of Luebeck, Luebeck, Germany</mods:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Section of Clinical and Molecular Neurogenetics at the Department of Neurology, University of Luebeck, Luebeck</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Kruger, Rejko" sort="Kruger, Rejko" uniqKey="Kruger R" first="Rejko" last="Kruger">Rejko Kruger</name>
<affiliation wicri:level="1">
<mods:affiliation>Department for Neurodegenerative Diseases, Hertie‐Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Tübingen, Germany</mods:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department for Neurodegenerative Diseases, Hertie‐Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Tübingen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Kyratzi, Elli" sort="Kyratzi, Elli" uniqKey="Kyratzi E" first="Elli" last="Kyratzi">Elli Kyratzi</name>
<affiliation wicri:level="1">
<mods:affiliation>Divisions of Basic Neurosciences and Cell Biology, Biomedical Research Foundation of the Academy of Athens, Athens, Greece</mods:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Divisions of Basic Neurosciences and Cell Biology, Biomedical Research Foundation of the Academy of Athens, Athens</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Lesage, Suzanne" sort="Lesage, Suzanne" uniqKey="Lesage S" first="Suzanne" last="Lesage">Suzanne Lesage</name>
<affiliation wicri:level="1">
<mods:affiliation>Université Pierre et Marie Curie‐Paris 6, Centre de Recherche de l'Institut du Cerveau et de la Moelle Épinière, Medical Research Unit S975, Paris, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Université Pierre et Marie Curie‐Paris 6, Centre de Recherche de l'Institut du Cerveau et de la Moelle Épinière, Medical Research Unit S975, Paris</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Institut National de la Santé et de la Recherche Médicale, Unit 975, Paris, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Santé et de la Recherche Médicale, Unit 975, Paris</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Centre National de la Recherche Scientifique, Medical Research Unit 7225, Paris, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre National de la Recherche Scientifique, Medical Research Unit 7225, Paris</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Lin, Chin Sien" sort="Lin, Chin Sien" uniqKey="Lin C" first="Chin-Hsien" last="Lin">Chin-Hsien Lin</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, National Taiwan University Hospital Yun‐Lin Branch, Yun‐Lin, Taiwan</mods:affiliation>
<country xml:lang="fr">Taïwan</country>
<wicri:regionArea>Department of Neurology, National Taiwan University Hospital Yun‐Lin Branch, Yun‐Lin</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Lynch, Timothy" sort="Lynch, Timothy" uniqKey="Lynch T" first="Timothy" last="Lynch">Timothy Lynch</name>
<affiliation wicri:level="1">
<mods:affiliation>Dublin Neurological Institute at the Mater Misericordiae University Hospital and Conway Institute of Biomolecular and Biomedical Research, University College, Dublin, Ireland</mods:affiliation>
<country xml:lang="fr">Irlande (pays)</country>
<wicri:regionArea>Dublin Neurological Institute at the Mater Misericordiae University Hospital and Conway Institute of Biomolecular and Biomedical Research, University College, Dublin</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Maraganore, Demetrius M" sort="Maraganore, Demetrius M" uniqKey="Maraganore D" first="Demetrius M." last="Maraganore">Demetrius M. Maraganore</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, North Shore University Health System, Illinois, Evanston, USA</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, North Shore University Health System, Illinois, Evanston</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Mellick, George D" sort="Mellick, George D" uniqKey="Mellick G" first="George D." last="Mellick">George D. Mellick</name>
<affiliation wicri:level="1">
<mods:affiliation>Eskitis Institute for Cell and Molecular Therapies, Griffith University, Queensland, Brisbane, Australia</mods:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Eskitis Institute for Cell and Molecular Therapies, Griffith University, Queensland, Brisbane</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Mutez, Eugenie" sort="Mutez, Eugenie" uniqKey="Mutez E" first="Eugénie" last="Mutez">Eugénie Mutez</name>
<affiliation wicri:level="1">
<mods:affiliation>University Lille Nord de France, Centre de Recherche Jean‐Pierre Aubert, Lille, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>University Lille Nord de France, Centre de Recherche Jean‐Pierre Aubert, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Institut National de la Santé et de la Recherche Médicale, Unit 837, Lille, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut National de la Santé et de la Recherche Médicale, Unit 837, Lille</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Centre Hospitalier Regional Universitaire de Lille, Lille, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre Hospitalier Regional Universitaire de Lille, Lille</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Nilsson, Christer" sort="Nilsson, Christer" uniqKey="Nilsson C" first="Christer" last="Nilsson">Christer Nilsson</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Clinical Sciences, Clinical Memory Research Unit, Lund University, Lund, Sweden</mods:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Clinical Memory Research Unit, Lund University, Lund</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Opala, Grzegorz" sort="Opala, Grzegorz" uniqKey="Opala G" first="Grzegorz" last="Opala">Grzegorz Opala</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Medical University of Silesia, Katowice, Poland</mods:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Neurology, Medical University of Silesia, Katowice</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Park, Sung Sup" sort="Park, Sung Sup" uniqKey="Park S" first="Sung Sup" last="Park">Sung Sup Park</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Laboratory Medicine, Seoul National University Hospital, Seoul, South Korea</mods:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Laboratory Medicine, Seoul National University Hospital, Seoul</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Petrucci, Simona" sort="Petrucci, Simona" uniqKey="Petrucci S" first="Simona" last="Petrucci">Simona Petrucci</name>
<affiliation wicri:level="1">
<mods:affiliation>Mendel Laboratory, Istituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy</mods:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Mendel Laboratory, Istituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Puschmann, Andreas" sort="Puschmann, Andreas" uniqKey="Puschmann A" first="Andreas" last="Puschmann">Andreas Puschmann</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Skåne University Hospital, Lund, Sweden</mods:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Neurology, Skåne University Hospital, Lund</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Clinical Sciences, Lund University, Lund, Sweden</mods:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Neurology, Clinical Sciences, Lund University, Lund</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Quattrone, Aldo" sort="Quattrone, Aldo" uniqKey="Quattrone A" first="Aldo" last="Quattrone">Aldo Quattrone</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Medical Sciences, Institute of Neurology, University Magna Graecia and Neuroimaging Research Unit, National Research Council, Catanzaro, Italy</mods:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Medical Sciences, Institute of Neurology, University Magna Graecia and Neuroimaging Research Unit, National Research Council, Catanzaro</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Sharma, Manu" sort="Sharma, Manu" uniqKey="Sharma M" first="Manu" last="Sharma">Manu Sharma</name>
<affiliation wicri:level="1">
<mods:affiliation>Department for Neurodegenerative Diseases, Hertie‐Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Tübingen, Germany</mods:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department for Neurodegenerative Diseases, Hertie‐Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Tübingen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Silburn, Peter A" sort="Silburn, Peter A" uniqKey="Silburn P" first="Peter A." last="Silburn">Peter A. Silburn</name>
<affiliation wicri:level="1">
<mods:affiliation>University of Queensland Centre for Clinical Research, Royal Brisbane Hospital, Queensland, Brisbane, Australia</mods:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>University of Queensland Centre for Clinical Research, Royal Brisbane Hospital, Queensland, Brisbane</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Sohn, Young Ho" sort="Sohn, Young Ho" uniqKey="Sohn Y" first="Young Ho" last="Sohn">Young Ho Sohn</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea</mods:affiliation>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Neurology, Yonsei University College of Medicine, Seoul</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Stefanis, Leonidas" sort="Stefanis, Leonidas" uniqKey="Stefanis L" first="Leonidas" last="Stefanis">Leonidas Stefanis</name>
<affiliation wicri:level="1">
<mods:affiliation>Divisions of Basic Neurosciences and Cell Biology, Biomedical Research Foundation of the Academy of Athens, Athens, Greece</mods:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Divisions of Basic Neurosciences and Cell Biology, Biomedical Research Foundation of the Academy of Athens, Athens</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Tadic, Vera" sort="Tadic, Vera" uniqKey="Tadic V" first="Vera" last="Tadic">Vera Tadic</name>
<affiliation wicri:level="1">
<mods:affiliation>Section of Clinical and Molecular Neurogenetics at the Department of Neurology, University of Luebeck, Luebeck, Germany</mods:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Section of Clinical and Molecular Neurogenetics at the Department of Neurology, University of Luebeck, Luebeck</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Theuns, Jessie" sort="Theuns, Jessie" uniqKey="Theuns J" first="Jessie" last="Theuns">Jessie Theuns</name>
<affiliation wicri:level="1">
<mods:affiliation>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium</mods:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Laboratory of Neurogenetics, Institute Born‐Bunge, University of Antwerp, Antwerp, Belgium</mods:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Laboratory of Neurogenetics, Institute Born‐Bunge, University of Antwerp, Antwerp</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Tomiyama, Hiroyuki" sort="Tomiyama, Hiroyuki" uniqKey="Tomiyama H" first="Hiroyuki" last="Tomiyama">Hiroyuki Tomiyama</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan</mods:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Juntendo University School of Medicine, Tokyo</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Uitti, Ryan J" sort="Uitti, Ryan J" uniqKey="Uitti R" first="Ryan J." last="Uitti">Ryan J. Uitti</name>
<affiliation wicri:level="1">
<mods:affiliation>Department of Neurology, Mayo Clinic, Florida, Jacksonville, USA</mods:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Mayo Clinic, Florida, Jacksonville</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Valente, Enza Maria" sort="Valente, Enza Maria" uniqKey="Valente E" first="Enza Maria" last="Valente">Enza Maria Valente</name>
<affiliation wicri:level="1">
<mods:affiliation>Mendel Laboratory, Istituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy</mods:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Mendel Laboratory, Istituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Van Broeckhoven, Christine" sort="Van Broeckhoven, Christine" uniqKey="Van Broeckhoven C" first="Christine" last="Van Broeckhoven">Christine Van Broeckhoven</name>
<affiliation wicri:level="1">
<mods:affiliation>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium</mods:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<mods:affiliation>Laboratory of Neurogenetics, Institute Born‐Bunge, University of Antwerp, Antwerp, Belgium</mods:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Laboratory of Neurogenetics, Institute Born‐Bunge, University of Antwerp, Antwerp</wicri:regionArea>
</affiliation>
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<name sortKey="Ross, Owen A" sort="Ross, Owen A" uniqKey="Ross O" first="Owen A." last="Ross">Owen A. Ross</name>
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</analytic>
<monogr></monogr>
<series>
<title level="j">Movement Disorders</title>
<title level="j" type="abbrev">Mov Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint>
<publisher>Blackwell Publishing Ltd</publisher>
<date type="published" when="2013-10">2013-10</date>
<biblScope unit="volume">28</biblScope>
<biblScope unit="issue">12</biblScope>
<biblScope unit="page" from="1740">1740</biblScope>
<biblScope unit="page" to="1744">1744</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">C6C03F04C791F2BAFA0887DE4DFC20A9DAE7F705</idno>
<idno type="DOI">10.1002/mds.25600</idno>
<idno type="ArticleID">MDS25600</idno>
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<idno type="ISSN">0885-3185</idno>
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<textClass></textClass>
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<language ident="en">en</language>
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</teiHeader>
<front>
<div type="abstract">Variants within the leucine‐rich repeat kinase 2 gene are recognized as the most frequent genetic cause of Parkinson's disease. Leucine‐rich repeat kinase 2 variation related to disease susceptibility displays many features that reflect the nature of complex, late‐onset sporadic disorders like Parkinson's disease.</div>
</front>
</TEI>
</record>

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