Tyrosine hydroxylase‐immunoreactive neurons in the nucleus basalis of the common marmoset (Callithrix jacchus)
Identifieur interne : 002426 ( Istex/Corpus ); précédent : 002425; suivant : 002427Tyrosine hydroxylase‐immunoreactive neurons in the nucleus basalis of the common marmoset (Callithrix jacchus)
Auteurs : L. Wisniowski ; R. M. Ridley ; H. F. Baker ; H. F. FineSource :
- Journal of Comparative Neurology [ 0021-9967 ] ; 1992-11-15.
English descriptors
Abstract
In the course of characterizing the distribution of putative catecholaminergic neurons in the brain of the common marmoset, we encountered a population of such cells in the basal forebrain. Tyrosine hydroxylase‐immunoreactive neurons are abundant within the nucleus basalis magnocellularis throughout its entire rostrocaudal extent, but not in other cholinergic basal forebrain nuclei. Most tyrosine hydroxylase‐immunoreactive cells are large and multipolar. Double staining with antibodies to choline acetyltransferase or nerve growth factor receptor confirmed that these tyrosine hydroxylase‐immunoreactive neurons are cholinergic, and compose at least 40% of the nucleus basalis cholinergic cells. The presence of a catecholamine‐synthesizing enzyme in the neurons that provide the major cholinergic input to the neocortex may have important consequences for cortical function, and may be relevant to the vulnerability of the nucleus basalis in certain neurodegenerative disorders. © 1992 Wiley‐Liss, Inc.
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DOI: 10.1002/cne.903250305
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Tyrosine hydroxylase‐immunoreactive neurons are abundant within the nucleus basalis magnocellularis throughout its entire rostrocaudal extent, but not in other cholinergic basal forebrain nuclei. Most tyrosine hydroxylase‐immunoreactive cells are large and multipolar. Double staining with antibodies to choline acetyltransferase or nerve growth factor receptor confirmed that these tyrosine hydroxylase‐immunoreactive neurons are cholinergic, and compose at least 40% of the nucleus basalis cholinergic cells. The presence of a catecholamine‐synthesizing enzyme in the neurons that provide the major cholinergic input to the neocortex may have important consequences for cortical function, and may be relevant to the vulnerability of the nucleus basalis in certain neurodegenerative disorders. © 1992 Wiley‐Liss, Inc.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>L. 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Tyrosine hydroxylase‐immunoreactive neurons are abundant within the nucleus basalis magnocellularis throughout its entire rostrocaudal extent, but not in other cholinergic basal forebrain nuclei. Most tyrosine hydroxylase‐immunoreactive cells are large and multipolar. Double staining with antibodies to choline acetyltransferase or nerve growth factor receptor confirmed that these tyrosine hydroxylase‐immunoreactive neurons are cholinergic, and compose at least 40% of the nucleus basalis cholinergic cells. The presence of a catecholamine‐synthesizing enzyme in the neurons that provide the major cholinergic input to the neocortex may have important consequences for cortical function, and may be relevant to the vulnerability of the nucleus basalis in certain neurodegenerative disorders. © 1992 Wiley‐Liss, Inc.</abstract><subject lang="en"><genre>keywords</genre><topic>acetylcholine</topic><topic>catecholamines</topic><topic>choline acetyltransferase</topic><topic>nerve growth factors</topic><topic>primates</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Comparative Neurology</title></titleInfo><titleInfo type="abbreviated"><title>J. Comp. 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|texte= Tyrosine hydroxylase‐immunoreactive neurons in the nucleus basalis of the common marmoset (Callithrix jacchus)
}}
| This area was generated with Dilib version V0.6.29. |  |