Memantine effects measured with the Relevant Outcome Scale for Alzheimer's disease in an open‐label, single‐arm, multicenter clinical study
Identifieur interne : 000097 ( Istex/Checkpoint ); précédent : 000096; suivant : 000098Memantine effects measured with the Relevant Outcome Scale for Alzheimer's disease in an open‐label, single‐arm, multicenter clinical study
Auteurs : Vjera Holthoff [Allemagne] ; Steven Ferris [États-Unis] ; Serge Gauthier [Canada] ; Ralf Ihl [Allemagne] ; Philippe Robert [France] ; Bengt Winblad [Suède] ; Kati Sternberg [Allemagne] ; Frank Tennigkeit [Suisse]Source :
- International Journal of Geriatric Psychiatry [ 0885-6230 ] ; 2013-02.
Abstract
The Relevant Outcome Scale for Alzheimer's disease (ROSA) is a novel, valid, and reliable instrument for multidimensional assessment of Alzheimer's disease (AD) symptoms across all severity stages. The ROSA and four standard instruments — the Alzheimer's disease Assessment Scale‐cognitive (ADAS‐cog), Severe Impairment Battery (SIB), Disability Assessment for Dementia (DAD), and the Neuropsychiatric Inventory (NPI) — were used in an open‐label, multicenter, single‐arm clinical study to assess treatment‐induced changes in cognitive, functional, and behavioral symptoms in patients with AD at different severity stages.
Url:
DOI: 10.1002/gps.3805
Affiliations:
- Allemagne, Canada, France, Suisse, Suède, États-Unis
- Canton de Vaud, District de Darmstadt, District de Dresde, Hesse (Land), Provence-Alpes-Côte d'Azur, Saxe (Land), Svealand, État de New York
- Dresde, Francfort-sur-le-Main, Lausanne, Nice, Stockholm
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<front><div type="abstract">The Relevant Outcome Scale for Alzheimer's disease (ROSA) is a novel, valid, and reliable instrument for multidimensional assessment of Alzheimer's disease (AD) symptoms across all severity stages. The ROSA and four standard instruments — the Alzheimer's disease Assessment Scale‐cognitive (ADAS‐cog), Severe Impairment Battery (SIB), Disability Assessment for Dementia (DAD), and the Neuropsychiatric Inventory (NPI) — were used in an open‐label, multicenter, single‐arm clinical study to assess treatment‐induced changes in cognitive, functional, and behavioral symptoms in patients with AD at different severity stages.</div>
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