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Memantine effects measured with the Relevant Outcome Scale for Alzheimer's disease in an open‐label, single‐arm, multicenter clinical study

Identifieur interne : 002810 ( Istex/Curation ); précédent : 002809; suivant : 002811

Memantine effects measured with the Relevant Outcome Scale for Alzheimer's disease in an open‐label, single‐arm, multicenter clinical study

Auteurs : Vjera Holthoff [Allemagne] ; Steven Ferris [États-Unis] ; Serge Gauthier [Canada] ; Ralf Ihl [Allemagne] ; Philippe Robert [France] ; Bengt Winblad [Suède] ; Kati Sternberg [Allemagne] ; Frank Tennigkeit [Suisse]

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RBID : ISTEX:2D337ABDB37D47E15A3E19A985D595D9E2A4675C

Abstract

The Relevant Outcome Scale for Alzheimer's disease (ROSA) is a novel, valid, and reliable instrument for multidimensional assessment of Alzheimer's disease (AD) symptoms across all severity stages. The ROSA and four standard instruments — the Alzheimer's disease Assessment Scale‐cognitive (ADAS‐cog), Severe Impairment Battery (SIB), Disability Assessment for Dementia (DAD), and the Neuropsychiatric Inventory (NPI) — were used in an open‐label, multicenter, single‐arm clinical study to assess treatment‐induced changes in cognitive, functional, and behavioral symptoms in patients with AD at different severity stages.

Url:
DOI: 10.1002/gps.3805

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ISTEX:2D337ABDB37D47E15A3E19A985D595D9E2A4675C

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