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Effect of orange juice intake on vitamin C concentrations and biomarkers of antioxidant status in humans.

Identifieur interne : 000E28 ( PubMed/Corpus ); précédent : 000E27; suivant : 000E29

Effect of orange juice intake on vitamin C concentrations and biomarkers of antioxidant status in humans.

Auteurs : Concepci N Sánchez-Moreno ; M Pilar Cano ; Bego A De Ancos ; Lucía Plaza ; Bego A Olmedilla ; Fernando Granado ; Antonio Martín

Source :

RBID : pubmed:12936929

English descriptors

Abstract

Consumption of fruit and vegetables is associated with improved health and a decreased prevalence of chronic degenerative processes.

PubMed: 12936929

Links to Exploration step

pubmed:12936929

Le document en format XML

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<title xml:lang="en">Effect of orange juice intake on vitamin C concentrations and biomarkers of antioxidant status in humans.</title>
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<name sortKey="Sanchez Moreno, Concepci N" sort="Sanchez Moreno, Concepci N" uniqKey="Sanchez Moreno C" first="Concepci N" last="Sánchez-Moreno">Concepci N Sánchez-Moreno</name>
<affiliation>
<nlm:affiliation>Nutrition and Neurocognitive Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA.</nlm:affiliation>
</affiliation>
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<name sortKey="Cano, M Pilar" sort="Cano, M Pilar" uniqKey="Cano M" first="M Pilar" last="Cano">M Pilar Cano</name>
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<author>
<name sortKey="De Ancos, Bego A" sort="De Ancos, Bego A" uniqKey="De Ancos B" first="Bego A" last="De Ancos">Bego A De Ancos</name>
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<name sortKey="Plaza, Lucia" sort="Plaza, Lucia" uniqKey="Plaza L" first="Lucía" last="Plaza">Lucía Plaza</name>
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<name sortKey="Olmedilla, Bego A" sort="Olmedilla, Bego A" uniqKey="Olmedilla B" first="Bego A" last="Olmedilla">Bego A Olmedilla</name>
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<name sortKey="Granado, Fernando" sort="Granado, Fernando" uniqKey="Granado F" first="Fernando" last="Granado">Fernando Granado</name>
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<name sortKey="Martin, Antonio" sort="Martin, Antonio" uniqKey="Martin A" first="Antonio" last="Martín">Antonio Martín</name>
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<title xml:lang="en">Effect of orange juice intake on vitamin C concentrations and biomarkers of antioxidant status in humans.</title>
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<name sortKey="Sanchez Moreno, Concepci N" sort="Sanchez Moreno, Concepci N" uniqKey="Sanchez Moreno C" first="Concepci N" last="Sánchez-Moreno">Concepci N Sánchez-Moreno</name>
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<nlm:affiliation>Nutrition and Neurocognitive Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA.</nlm:affiliation>
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<name sortKey="Cano, M Pilar" sort="Cano, M Pilar" uniqKey="Cano M" first="M Pilar" last="Cano">M Pilar Cano</name>
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<name sortKey="De Ancos, Bego A" sort="De Ancos, Bego A" uniqKey="De Ancos B" first="Bego A" last="De Ancos">Bego A De Ancos</name>
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<name sortKey="Plaza, Lucia" sort="Plaza, Lucia" uniqKey="Plaza L" first="Lucía" last="Plaza">Lucía Plaza</name>
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<name sortKey="Olmedilla, Bego A" sort="Olmedilla, Bego A" uniqKey="Olmedilla B" first="Bego A" last="Olmedilla">Bego A Olmedilla</name>
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<name sortKey="Granado, Fernando" sort="Granado, Fernando" uniqKey="Granado F" first="Fernando" last="Granado">Fernando Granado</name>
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<name sortKey="Martin, Antonio" sort="Martin, Antonio" uniqKey="Martin A" first="Antonio" last="Martín">Antonio Martín</name>
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<title level="j">The American journal of clinical nutrition</title>
<idno type="ISSN">0002-9165</idno>
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<term>Adult</term>
<term>Antioxidants</term>
<term>Ascorbic Acid (blood)</term>
<term>Beverages</term>
<term>Biological Availability</term>
<term>Biomarkers (blood)</term>
<term>Citrus sinensis</term>
<term>Dinoprost (analogs & derivatives)</term>
<term>Dinoprost (blood)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Oxidative Stress</term>
<term>Smoking (blood)</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en">
<term>Dinoprost</term>
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<term>Ascorbic Acid</term>
<term>Biomarkers</term>
<term>Dinoprost</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en">
<term>Antioxidants</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en">
<term>Smoking</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Beverages</term>
<term>Biological Availability</term>
<term>Citrus sinensis</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Oxidative Stress</term>
<term>Time Factors</term>
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<front>
<div type="abstract" xml:lang="en">Consumption of fruit and vegetables is associated with improved health and a decreased prevalence of chronic degenerative processes.</div>
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<Year>2003</Year>
<Month>8</Month>
<Day>25</Day>
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<DateCompleted>
<Year>2003</Year>
<Month>09</Month>
<Day>26</Day>
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<Year>2015</Year>
<Month>11</Month>
<Day>19</Day>
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<Volume>78</Volume>
<Issue>3</Issue>
<PubDate>
<Year>2003</Year>
<Month>Sep</Month>
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<Title>The American journal of clinical nutrition</Title>
<ISOAbbreviation>Am. J. Clin. Nutr.</ISOAbbreviation>
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<ArticleTitle>Effect of orange juice intake on vitamin C concentrations and biomarkers of antioxidant status in humans.</ArticleTitle>
<Pagination>
<MedlinePgn>454-60</MedlinePgn>
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<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Consumption of fruit and vegetables is associated with improved health and a decreased prevalence of chronic degenerative processes.</AbstractText>
<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">The objectives were to assess the bioavailability of vitamin C from orange juice and its influence on plasma vitamin C and 8-epi-prostaglandin F(2 alpha) (8-epi-PGF(2 alpha)) concentrations in a healthy human population.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Six men and 6 women consumed 500 mL commercial fresh-squeezed orange juice/d for 14 d, corresponding to an intake of 250 mg ascorbic acid/d. On the first day of the study, the subjects drank the juice in one dose (dose-response study), and on days 2-14 they consumed 250 mL in the morning and 250 mL in the afternoon. Blood was collected every hour for 6 h on the first day and again on days 7 and 14.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Baseline plasma vitamin C concentrations were significantly higher (P = 0.03) among the women than among the men (56.4 +/- 4.4 compared with 44.3 +/- 3.5 micromol/L). In the dose-response study, the maximum increase in plasma vitamin C occurred 3 h postdose in both the men and the women. Vitamin C concentrations remained significantly higher on days 7 and 14 than at baseline. Baseline concentrations of 8-epi-PGF(2 alpha) were significantly higher (P = 0.03) among the men than among the women (249.6 +/- 25.4 compared with 177.7 +/- 6.2 pg/mL) but decreased significantly (P = 0.04) by day 14 of the intervention. A significant inverse correlation was observed between vitamin C and 8-epi-PGF(2 alpha) (r = -0.791, P = 0.0022). Among smokers, baseline vitamin C was lower and 8-epi-PGF(2 alpha) higher than among nonsmokers.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Drinking orange juice (500 mL/d) increases plasma concentrations of vitamin C and reduces concentrations of 8-epi-PGF(2 alpha) in humans. These effects were significantly more pronounced in smokers.</AbstractText>
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