Restoration of radiation injury in mice by two Chinese medicinal prescriptions Kuei‐Pi‐Tang and Jen‐Sheng‐Yang‐Yung‐Tang
Identifieur interne : 001129 ( Istex/Checkpoint ); précédent : 001128; suivant : 001130Restoration of radiation injury in mice by two Chinese medicinal prescriptions Kuei‐Pi‐Tang and Jen‐Sheng‐Yang‐Yung‐Tang
Auteurs : Hsue-Yin Hsu [Taïwan] ; Chun-Ching Lin [Taïwan] ; Dou-Mong Hau [Taïwan]Source :
- Phytotherapy Research [ 0951-418X ] ; 1992-11.
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Abstract
A comparison of Kuei‐Pi‐Tang and Jen‐Sheng‐Yang‐Yung‐Tang, two traditional Chinese medicines, on promoting the recovery of mice from radiation‐induced damage was studied by using the measurements of colony forming stem cells in spleen, the appearance of occult blood in feces and changes of hemograms after x‐irradiation. Different sequences of x‐irradiation were studied with or without drug administration in groups of ICR strain mice which were intraperitoneally injected at a concentration of 10 or 20 mg/20 g body weight, once a day for 7 consecutive days. Kuei‐Pi‐Tang showed no significant difference on the efficacy of recovery from hemorrhage and hemograms, as compared with that of Jen‐Sheng‐Yang‐Yung‐Tang. In contrast, the effect of Kuei‐Pi‐Tang on the recovery of CPUs was more likely induced by eliminating the radiosensitivity of bone marrow cells. However, Jen‐Sheng‐Yang‐Yung‐Tang appears to increase the radiotolerance of the cells. The recovery of thrombocyte counts which was reported to have an important influence on the survival ratio coincided with that of the recovery from hemorrhage.
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DOI: 10.1002/ptr.2650060603
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Res.</title><idno type="ISSN">0951-418X</idno><idno type="eISSN">1099-1573</idno><imprint><publisher>John Wiley & Sons, Ltd.</publisher><pubPlace>Chichester, UK</pubPlace><date type="published" when="1992-11">1992-11</date><biblScope unit="volume">6</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="294">294</biblScope><biblScope unit="page" to="299">299</biblScope></imprint><idno type="ISSN">0951-418X</idno></series><idno type="istex">5636835FE7B5B87190CED34365456D2B6C32A744</idno><idno type="DOI">10.1002/ptr.2650060603</idno><idno type="ArticleID">PTR2650060603</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0951-418X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>CFUs</term><term>Jen‐Sheng‐Yang‐Yung‐Tang</term><term>Kuei‐Pi‐Tang</term><term>haemograms</term><term>haemorrhage</term><term>radiation‐induced damage in mice</term><term>traditional Chinese medicine</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A comparison of Kuei‐Pi‐Tang and Jen‐Sheng‐Yang‐Yung‐Tang, two traditional Chinese medicines, on promoting the recovery of mice from radiation‐induced damage was studied by using the measurements of colony forming stem cells in spleen, the appearance of occult blood in feces and changes of hemograms after x‐irradiation. Different sequences of x‐irradiation were studied with or without drug administration in groups of ICR strain mice which were intraperitoneally injected at a concentration of 10 or 20 mg/20 g body weight, once a day for 7 consecutive days. Kuei‐Pi‐Tang showed no significant difference on the efficacy of recovery from hemorrhage and hemograms, as compared with that of Jen‐Sheng‐Yang‐Yung‐Tang. In contrast, the effect of Kuei‐Pi‐Tang on the recovery of CPUs was more likely induced by eliminating the radiosensitivity of bone marrow cells. However, Jen‐Sheng‐Yang‐Yung‐Tang appears to increase the radiotolerance of the cells. The recovery of thrombocyte counts which was reported to have an important influence on the survival ratio coincided with that of the recovery from hemorrhage.</div></front></TEI><affiliations><list><country><li>Taïwan</li></country></list><tree><country name="Taïwan"><noRegion><name sortKey="Hsu, Hsue In" sort="Hsu, Hsue In" uniqKey="Hsu H" first="Hsue-Yin" last="Hsu">Hsue-Yin Hsu</name></noRegion><name sortKey="Hau, Dou Ong" sort="Hau, Dou Ong" uniqKey="Hau D" first="Dou-Mong" last="Hau">Dou-Mong Hau</name><name sortKey="Lin, Chun Hing" sort="Lin, Chun Hing" uniqKey="Lin C" first="Chun-Ching" last="Lin">Chun-Ching Lin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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