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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Association of Age at First Sex with HIV-1, HSV-2 and other Sexual Transmitted Infections among Women in Northern Tanzania</title><author><name sortKey="Ghebremichael, Musie" sort="Ghebremichael, Musie" uniqKey="Ghebremichael M" first="Musie" last="Ghebremichael">Musie Ghebremichael</name><affiliation><nlm:aff id="A1">Harvard University School of Public Healt, Boston, Massachusetts</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Dana Farber Cancer Institute, Boston, Massachusetts</nlm:aff></affiliation></author><author><name sortKey="Larsen, Ulla" sort="Larsen, Ulla" uniqKey="Larsen U" first="Ulla" last="Larsen">Ulla Larsen</name><affiliation><nlm:aff id="A3">Department of Sociology, University of Maryland, College Park, Maryland</nlm:aff></affiliation></author><author><name sortKey="Paintsil, Elijah" sort="Paintsil, Elijah" uniqKey="Paintsil E" first="Elijah" last="Paintsil">Elijah Paintsil</name><affiliation><nlm:aff id="A4">Departments of Pediatrics and Pharmacology, Yale University School of Medicine, New Haven, Connecticut</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">19707109</idno><idno type="pmc">3529537</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529537</idno><idno type="RBID">PMC:3529537</idno><idno type="doi">10.1097/OLQ.0b013e3181a866b8</idno><date when="2009">2009</date><idno type="wicri:Area/Pmc/Corpus">001B85</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001B85</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Association of Age at First Sex with HIV-1, HSV-2 and other Sexual Transmitted Infections among Women in Northern Tanzania</title><author><name sortKey="Ghebremichael, Musie" sort="Ghebremichael, Musie" uniqKey="Ghebremichael M" first="Musie" last="Ghebremichael">Musie Ghebremichael</name><affiliation><nlm:aff id="A1">Harvard University School of Public Healt, Boston, Massachusetts</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Dana Farber Cancer Institute, Boston, Massachusetts</nlm:aff></affiliation></author><author><name sortKey="Larsen, Ulla" sort="Larsen, Ulla" uniqKey="Larsen U" first="Ulla" last="Larsen">Ulla Larsen</name><affiliation><nlm:aff id="A3">Department of Sociology, University of Maryland, College Park, Maryland</nlm:aff></affiliation></author><author><name sortKey="Paintsil, Elijah" sort="Paintsil, Elijah" uniqKey="Paintsil E" first="Elijah" last="Paintsil">Elijah Paintsil</name><affiliation><nlm:aff id="A4">Departments of Pediatrics and Pharmacology, Yale University School of Medicine, New Haven, Connecticut</nlm:aff></affiliation></author></analytic><series><title level="j">Sexually transmitted diseases</title><idno type="ISSN">0148-5717</idno><idno type="eISSN">1537-4521</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title><p id="P1">To examine the association between age at first sex and the prevalence of sexually transmitted infections (STIs) including, HIV-1, and HSV-2 in women in Moshi urban district, northern Tanzania.</p></sec><sec id="S2"><title>Methods</title><p id="P2">A total of 2,019 women aged 20–44 were randomly selected in a two-stage sampling from Moshi urban district, northern Tanzania. Information on demographics and sexual behaviors were obtained. Blood and urine samples were drawn for testing of HIV-1, HSV-2 and other STIs.</p></sec><sec id="S3"><title>Results</title><p id="P3">Women who had their first sexual intercourse at age 18–19 (OR=0.66; 95% CI=0.50–0.86) or 20+ (OR=0.46; 95% CI=0.36–0.60) were less likely to have STIs, including HIV-1 and HSV-2, than women who had their first intercourse before their 18<sup>th</sup> birthday. The hazards of having had first sex at an earlier age were significantly higher for women who tested positive for STIs (HR=1.52; 95% CI: 1.37–1.69) or had STI symptoms (HR=1.17; 95% CI: 1.05–1.30). Early age at first sex was associated with having a regular non-cohabiting partner (HR=1.40; 95% CI: 1.23–1.58), female circumcision (HR=1.20; 95% CI: 1.02–1.40), and coercion at first intercourse (HR=1.47; 95% CI: 1.15–1.89).</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">In sub-Saharan Africa, where the prevalence of HIV and other STIs is high, a better understanding of the determinants of the age at first sex is crucial for HIV/STI prevention programs. Prevention programs should not only aim at delaying the age at first sex but also address factors leading to early age at first sex.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">7705941</journal-id><journal-id journal-id-type="pubmed-jr-id">7382</journal-id><journal-id journal-id-type="nlm-ta">Sex Transm Dis</journal-id><journal-id journal-id-type="iso-abbrev">Sex Transm Dis</journal-id><journal-title-group><journal-title>Sexually transmitted diseases</journal-title></journal-title-group><issn pub-type="ppub">0148-5717</issn><issn pub-type="epub">1537-4521</issn></journal-meta><article-meta><article-id pub-id-type="pmid">19707109</article-id><article-id pub-id-type="pmc">3529537</article-id><article-id pub-id-type="doi">10.1097/OLQ.0b013e3181a866b8</article-id><article-id pub-id-type="manuscript">NIHMS427215</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Association of Age at First Sex with HIV-1, HSV-2 and other Sexual Transmitted Infections among Women in Northern Tanzania</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ghebremichael</surname><given-names>Musie</given-names></name><degrees>PhD,</degrees><xref ref-type="aff" rid="A1">*</xref><xref ref-type="aff" rid="A2">†</xref></contrib><contrib contrib-type="author"><name><surname>Larsen</surname><given-names>Ulla</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="A3">§</xref></contrib><contrib contrib-type="author"><name><surname>Paintsil</surname><given-names>Elijah</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="A4">‡</xref></contrib></contrib-group><aff id="A1"><label>*</label>Harvard University School of Public Healt, Boston, Massachusetts</aff><aff id="A2"><label>†</label>Dana Farber Cancer Institute, Boston, Massachusetts</aff><aff id="A3"><label>§</label>Department of Sociology, University of Maryland, College Park, Maryland</aff><aff id="A4"><label>‡</label>Departments of Pediatrics and Pharmacology, Yale University School of Medicine, New Haven, Connecticut</aff><author-notes><corresp id="cor1">Correspondence to: Musie Ghebremichael, Ph.D., Dana Farber Cancer Center Institute and Harvard University School of Public Health, 3 Blackfan Circle, CLS-11045, Boston, MA 02115, USA. Phone: 617-632-5868 Fax: 617-632-2444: <email>musie@jimmy.harvard.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>19</day><month>12</month><year>2012</year></pub-date><pub-date pub-type="ppub"><month>9</month><year>2009</year></pub-date><pub-date pub-type="pmc-release"><day>24</day><month>12</month><year>2012</year></pub-date><volume>36</volume><issue>9</issue><fpage>570</fpage><lpage>576</lpage><abstract><sec id="S1"><title>Background</title><p id="P1">To examine the association between age at first sex and the prevalence of sexually transmitted infections (STIs) including, HIV-1, and HSV-2 in women in Moshi urban district, northern Tanzania.</p></sec><sec id="S2"><title>Methods</title><p id="P2">A total of 2,019 women aged 20–44 were randomly selected in a two-stage sampling from Moshi urban district, northern Tanzania. Information on demographics and sexual behaviors were obtained. Blood and urine samples were drawn for testing of HIV-1, HSV-2 and other STIs.</p></sec><sec id="S3"><title>Results</title><p id="P3">Women who had their first sexual intercourse at age 18–19 (OR=0.66; 95% CI=0.50–0.86) or 20+ (OR=0.46; 95% CI=0.36–0.60) were less likely to have STIs, including HIV-1 and HSV-2, than women who had their first intercourse before their 18<sup>th</sup> birthday. The hazards of having had first sex at an earlier age were significantly higher for women who tested positive for STIs (HR=1.52; 95% CI: 1.37–1.69) or had STI symptoms (HR=1.17; 95% CI: 1.05–1.30). Early age at first sex was associated with having a regular non-cohabiting partner (HR=1.40; 95% CI: 1.23–1.58), female circumcision (HR=1.20; 95% CI: 1.02–1.40), and coercion at first intercourse (HR=1.47; 95% CI: 1.15–1.89).</p></sec><sec id="S4"><title>Conclusions</title><p id="P4">In sub-Saharan Africa, where the prevalence of HIV and other STIs is high, a better understanding of the determinants of the age at first sex is crucial for HIV/STI prevention programs. Prevention programs should not only aim at delaying the age at first sex but also address factors leading to early age at first sex.</p></sec></abstract><kwd-group><kwd>Age of at first sex</kwd><kwd>sexually transmitted infections</kwd><kwd>marginal Cox model</kwd><kwd>mixed models</kwd><kwd>sub-Saharan Africa</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</funding-source><award-id>P30 AI060354 || AI</award-id></award-group><award-group><funding-source country="United States">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</funding-source><award-id>K08 AI074404 || AI</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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