Serum nickel concentration in normal menstrual cycle and after combined contraceptive pill.
Identifieur interne : 000172 ( Ncbi/Curation ); précédent : 000171; suivant : 000173Serum nickel concentration in normal menstrual cycle and after combined contraceptive pill.
Auteurs : S. Nayel ; M. Zahran ; A A Gawad ; A. Mokhtar ; S. Gawish ; G. El-TabbakhSource :
- Contraception [ 0010-7824 ] ; 1986.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Nickel.
- chemical , pharmacology : Contraceptives, Oral, Combined.
- Adolescent, Adult, Female, Humans, Menstrual Cycle, Spectrophotometry, Atomic, Time Factors.
Abstract
Serum nickel concentration in the different phases of the menstrual cycle and after use of a combined contraceptive pill (Anovlar) was determined by atomic absorption spectrophotometry. Twenty ovulating females had their serum nickel level measured on day 5 and on day 27 of their cycle. Forty females using Anovlar for 6 months and 40 females using it for more than 3 years had their serum nickel determined. The serum nickel concentration of the non-pill users was higher on day 5 (2.52 +/- 0.46 micrograms/L) than on day 27 (2.21 +/- 0.37 micrograms/L p less than 0.05). In long-term users, the serum nickel (0.98 +/- 0.38 microgram/L) was less than the short-term users (2.38 +/- 0.35 micrograms/L, p less than 0.01) and the non-users (p less than 0.01). There was a negative correlation between the duration of pill use and the serum nickel level (r = -0.44, p less than 0.01). The significance of the decreased serum nickel level with long-term pill use remains to be determined.
PubMed: 3780237
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pubmed:3780237Le document en format XML
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<author><name sortKey="Nayel, S" sort="Nayel, S" uniqKey="Nayel S" first="S" last="Nayel">S. Nayel</name>
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<author><name sortKey="Zahran, M" sort="Zahran, M" uniqKey="Zahran M" first="M" last="Zahran">M. Zahran</name>
</author>
<author><name sortKey="Gawad, A A" sort="Gawad, A A" uniqKey="Gawad A" first="A A" last="Gawad">A A Gawad</name>
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<author><name sortKey="Mokhtar, A" sort="Mokhtar, A" uniqKey="Mokhtar A" first="A" last="Mokhtar">A. Mokhtar</name>
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<author><name sortKey="Gawish, S" sort="Gawish, S" uniqKey="Gawish S" first="S" last="Gawish">S. Gawish</name>
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<author><name sortKey="El Tabbakh, G" sort="El Tabbakh, G" uniqKey="El Tabbakh G" first="G" last="El-Tabbakh">G. El-Tabbakh</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Serum nickel concentration in normal menstrual cycle and after combined contraceptive pill.</title>
<author><name sortKey="Nayel, S" sort="Nayel, S" uniqKey="Nayel S" first="S" last="Nayel">S. Nayel</name>
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<author><name sortKey="Zahran, M" sort="Zahran, M" uniqKey="Zahran M" first="M" last="Zahran">M. Zahran</name>
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<author><name sortKey="Mokhtar, A" sort="Mokhtar, A" uniqKey="Mokhtar A" first="A" last="Mokhtar">A. Mokhtar</name>
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<author><name sortKey="Gawish, S" sort="Gawish, S" uniqKey="Gawish S" first="S" last="Gawish">S. Gawish</name>
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<author><name sortKey="El Tabbakh, G" sort="El Tabbakh, G" uniqKey="El Tabbakh G" first="G" last="El-Tabbakh">G. El-Tabbakh</name>
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<series><title level="j">Contraception</title>
<idno type="ISSN">0010-7824</idno>
<imprint><date when="1986" type="published">1986</date>
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<term>Adult</term>
<term>Contraceptives, Oral, Combined (pharmacology)</term>
<term>Female</term>
<term>Humans</term>
<term>Menstrual Cycle</term>
<term>Nickel (blood)</term>
<term>Spectrophotometry, Atomic</term>
<term>Time Factors</term>
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<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Nickel</term>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Contraceptives, Oral, Combined</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
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<term>Spectrophotometry, Atomic</term>
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<front><div type="abstract" xml:lang="en">Serum nickel concentration in the different phases of the menstrual cycle and after use of a combined contraceptive pill (Anovlar) was determined by atomic absorption spectrophotometry. Twenty ovulating females had their serum nickel level measured on day 5 and on day 27 of their cycle. Forty females using Anovlar for 6 months and 40 females using it for more than 3 years had their serum nickel determined. The serum nickel concentration of the non-pill users was higher on day 5 (2.52 +/- 0.46 micrograms/L) than on day 27 (2.21 +/- 0.37 micrograms/L p less than 0.05). In long-term users, the serum nickel (0.98 +/- 0.38 microgram/L) was less than the short-term users (2.38 +/- 0.35 micrograms/L, p less than 0.01) and the non-users (p less than 0.01). There was a negative correlation between the duration of pill use and the serum nickel level (r = -0.44, p less than 0.01). The significance of the decreased serum nickel level with long-term pill use remains to be determined.</div>
</front>
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