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Serum nickel concentration in normal menstrual cycle and after combined contraceptive pill.

Identifieur interne : 000140 ( PubMed/Curation ); précédent : 000139; suivant : 000141

Serum nickel concentration in normal menstrual cycle and after combined contraceptive pill.

Auteurs : S. Nayel ; M. Zahran ; A A Gawad ; A. Mokhtar ; S. Gawish ; G. El-Tabbakh

Source :

RBID : pubmed:3780237

English descriptors

Abstract

Serum nickel concentration in the different phases of the menstrual cycle and after use of a combined contraceptive pill (Anovlar) was determined by atomic absorption spectrophotometry. Twenty ovulating females had their serum nickel level measured on day 5 and on day 27 of their cycle. Forty females using Anovlar for 6 months and 40 females using it for more than 3 years had their serum nickel determined. The serum nickel concentration of the non-pill users was higher on day 5 (2.52 +/- 0.46 micrograms/L) than on day 27 (2.21 +/- 0.37 micrograms/L p less than 0.05). In long-term users, the serum nickel (0.98 +/- 0.38 microgram/L) was less than the short-term users (2.38 +/- 0.35 micrograms/L, p less than 0.01) and the non-users (p less than 0.01). There was a negative correlation between the duration of pill use and the serum nickel level (r = -0.44, p less than 0.01). The significance of the decreased serum nickel level with long-term pill use remains to be determined.

PubMed: 3780237

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Le document en format XML

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<name sortKey="Zahran, M" sort="Zahran, M" uniqKey="Zahran M" first="M" last="Zahran">M. Zahran</name>
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<name sortKey="Gawad, A A" sort="Gawad, A A" uniqKey="Gawad A" first="A A" last="Gawad">A A Gawad</name>
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<name sortKey="Mokhtar, A" sort="Mokhtar, A" uniqKey="Mokhtar A" first="A" last="Mokhtar">A. Mokhtar</name>
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<name sortKey="Gawish, S" sort="Gawish, S" uniqKey="Gawish S" first="S" last="Gawish">S. Gawish</name>
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<name sortKey="El Tabbakh, G" sort="El Tabbakh, G" uniqKey="El Tabbakh G" first="G" last="El-Tabbakh">G. El-Tabbakh</name>
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<term>Menstrual Cycle</term>
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<term>Spectrophotometry, Atomic</term>
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<div type="abstract" xml:lang="en">Serum nickel concentration in the different phases of the menstrual cycle and after use of a combined contraceptive pill (Anovlar) was determined by atomic absorption spectrophotometry. Twenty ovulating females had their serum nickel level measured on day 5 and on day 27 of their cycle. Forty females using Anovlar for 6 months and 40 females using it for more than 3 years had their serum nickel determined. The serum nickel concentration of the non-pill users was higher on day 5 (2.52 +/- 0.46 micrograms/L) than on day 27 (2.21 +/- 0.37 micrograms/L p less than 0.05). In long-term users, the serum nickel (0.98 +/- 0.38 microgram/L) was less than the short-term users (2.38 +/- 0.35 micrograms/L, p less than 0.01) and the non-users (p less than 0.01). There was a negative correlation between the duration of pill use and the serum nickel level (r = -0.44, p less than 0.01). The significance of the decreased serum nickel level with long-term pill use remains to be determined.</div>
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<Title>Contraception</Title>
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<AbstractText>Serum nickel concentration in the different phases of the menstrual cycle and after use of a combined contraceptive pill (Anovlar) was determined by atomic absorption spectrophotometry. Twenty ovulating females had their serum nickel level measured on day 5 and on day 27 of their cycle. Forty females using Anovlar for 6 months and 40 females using it for more than 3 years had their serum nickel determined. The serum nickel concentration of the non-pill users was higher on day 5 (2.52 +/- 0.46 micrograms/L) than on day 27 (2.21 +/- 0.37 micrograms/L p less than 0.05). In long-term users, the serum nickel (0.98 +/- 0.38 microgram/L) was less than the short-term users (2.38 +/- 0.35 micrograms/L, p less than 0.01) and the non-users (p less than 0.01). There was a negative correlation between the duration of pill use and the serum nickel level (r = -0.44, p less than 0.01). The significance of the decreased serum nickel level with long-term pill use remains to be determined.</AbstractText>
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<AbstractText>Serum nickel concentration in the different phases of the menstrual cycle and after use of a combined contraceptive pill (Anovlar) was determined by atomic absorption spectrophotometry. 20 ovulating females had their serum nickel level measured on day 5 and on day 27 of their cycle. 40 females using Anovlar for 6 months and 40 females using it for more than 3 years had their serum nickel determined. The serum nickel concentration of the non-pill users was higher on day 5 (2.52 + or - 0.46 ug/L) than on day 27 (2.21 + or - 0.37 ug/L). In long-term users, the serum nickel (0.98 + or - ug/L) was less than the short-term users (2.38 + or - 0.35 ug/L) and the non-users. There was a negative correlation between the duration of pill use and the serum nickel level. The significance of the decreased serum nickel level with long-term pill use remains to be determined.</AbstractText>
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<Keyword MajorTopicYN="N">Africa</Keyword>
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