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<title xml:lang="en">Using the Generic Synteny Browser (GBrowse_syn)</title>
<author>
<name sortKey="Mckay, Sheldon J" sort="Mckay, Sheldon J" uniqKey="Mckay S" first="Sheldon J." last="Mckay">Sheldon J. Mckay</name>
<affiliation>
<nlm:aff id="A1"> Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Vergara, Ismael A" sort="Vergara, Ismael A" uniqKey="Vergara I" first="Ismael A." last="Vergara">Ismael A. Vergara</name>
<affiliation>
<nlm:aff id="A2"> Simon Fraser University, Burnaby, BC, Canada</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Stajich, Jason E" sort="Stajich, Jason E" uniqKey="Stajich J" first="Jason E." last="Stajich">Jason E. Stajich</name>
<affiliation>
<nlm:aff id="A3"> University of California Riverside, CA, USA</nlm:aff>
</affiliation>
</author>
</titleStmt>
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<idno type="wicri:source">PMC</idno>
<idno type="pmid">20836076</idno>
<idno type="pmc">3162311</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162311</idno>
<idno type="RBID">PMC:3162311</idno>
<idno type="doi">10.1002/0471250953.bi0912s31</idno>
<date when="2010">2010</date>
<idno type="wicri:Area/Pmc/Corpus">000318</idno>
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<title xml:lang="en" level="a" type="main">Using the Generic Synteny Browser (GBrowse_syn)</title>
<author>
<name sortKey="Mckay, Sheldon J" sort="Mckay, Sheldon J" uniqKey="Mckay S" first="Sheldon J." last="Mckay">Sheldon J. Mckay</name>
<affiliation>
<nlm:aff id="A1"> Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Vergara, Ismael A" sort="Vergara, Ismael A" uniqKey="Vergara I" first="Ismael A." last="Vergara">Ismael A. Vergara</name>
<affiliation>
<nlm:aff id="A2"> Simon Fraser University, Burnaby, BC, Canada</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Stajich, Jason E" sort="Stajich, Jason E" uniqKey="Stajich J" first="Jason E." last="Stajich">Jason E. Stajich</name>
<affiliation>
<nlm:aff id="A3"> University of California Riverside, CA, USA</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.]</title>
<idno type="ISSN">1934-3396</idno>
<idno type="eISSN">1934-340X</idno>
<imprint>
<date when="2010">2010</date>
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<front>
<div type="abstract" xml:lang="en">
<p id="P1">Genome Browsers are software that allow the user to view genome annotations in the context of a reference sequence, such as a chromosome, contig, scaffold, etc. The Generic Genome Browser (GBrowse) is an open source genome browser package developed as part of the Generic Model Database Project (see Unit 9.9;
<xref ref-type="bibr" rid="R7">Stein et at., 2002</xref>
). The increasing number of sequenced genomes has to a corresponding growth in the field of comparative genomics, which requires methods to view and compare multiple genomes. Using the same software framework as GBrowse, the Generic Synteny Browser (GBrowse_syn) allows the comparison of co-linear regions of multiple genomes using the familiar GBrowse-style web page. Like GBrowse, GBrowse_syn can be configured to display any organism and is currently the synteny browser used for model organisms such as
<italic>C. elegans</italic>
(WormBase;
<ext-link ext-link-type="uri" xlink:href="http://www.wormbase.org">www.wormbase.org</ext-link>
; see Unit 1.8) and
<italic>Arabidopsis</italic>
(TAIR;
<ext-link ext-link-type="uri" xlink:href="http://www.arabidopsis.org">www.arabidopsis.org</ext-link>
; see Unit 1.11). GBrowse_syn is part of the GBrowse software package and can be downloaded from the web and run on any unix-like operating system, such as Linux, Solaris, Mac OS X etc. GBrowse_syn is still under active development. This unit will cover installation and configuration as part of the current stable version of GBrowse (v1.71).</p>
</div>
</front>
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<pmc article-type="research-article" xml:lang="en">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-journal-id">101157830</journal-id>
<journal-id journal-id-type="pubmed-jr-id">34237</journal-id>
<journal-id journal-id-type="nlm-ta">Curr Protoc Bioinformatics</journal-id>
<journal-title-group>
<journal-title>Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.]</journal-title>
</journal-title-group>
<issn pub-type="ppub">1934-3396</issn>
<issn pub-type="epub">1934-340X</issn>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">20836076</article-id>
<article-id pub-id-type="pmc">3162311</article-id>
<article-id pub-id-type="doi">10.1002/0471250953.bi0912s31</article-id>
<article-id pub-id-type="manuscript">NIHMS234286</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
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<title-group>
<article-title>Using the Generic Synteny Browser (GBrowse_syn)</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>McKay</surname>
<given-names>Sheldon J.</given-names>
</name>
<xref rid="A1" ref-type="aff">1</xref>
<xref rid="FN1" ref-type="author-notes">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Vergara</surname>
<given-names>Ismael A.</given-names>
</name>
<xref rid="A2" ref-type="aff">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Stajich</surname>
<given-names>Jason E.</given-names>
</name>
<xref rid="A3" ref-type="aff">4</xref>
</contrib>
</contrib-group>
<aff id="A1">
<label>1</label>
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA</aff>
<aff id="A2">
<label>3</label>
Simon Fraser University, Burnaby, BC, Canada</aff>
<aff id="A3">
<label>4</label>
University of California Riverside, CA, USA</aff>
<author-notes>
<fn id="FN1" fn-type="present-address">
<label>2</label>
<p>Current Address: University of Arizona, Tucson, AZ, USA</p>
</fn>
</author-notes>
<pub-date pub-type="nihms-submitted">
<day>28</day>
<month>3</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="ppub">
<month>9</month>
<year>2010</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>26</day>
<month>8</month>
<year>2011</year>
</pub-date>
<volume>CHAPTER</volume>
<fpage>Unit</fpage>
<lpage>9.12</lpage>
<abstract>
<p id="P1">Genome Browsers are software that allow the user to view genome annotations in the context of a reference sequence, such as a chromosome, contig, scaffold, etc. The Generic Genome Browser (GBrowse) is an open source genome browser package developed as part of the Generic Model Database Project (see Unit 9.9;
<xref ref-type="bibr" rid="R7">Stein et at., 2002</xref>
). The increasing number of sequenced genomes has to a corresponding growth in the field of comparative genomics, which requires methods to view and compare multiple genomes. Using the same software framework as GBrowse, the Generic Synteny Browser (GBrowse_syn) allows the comparison of co-linear regions of multiple genomes using the familiar GBrowse-style web page. Like GBrowse, GBrowse_syn can be configured to display any organism and is currently the synteny browser used for model organisms such as
<italic>C. elegans</italic>
(WormBase;
<ext-link ext-link-type="uri" xlink:href="http://www.wormbase.org">www.wormbase.org</ext-link>
; see Unit 1.8) and
<italic>Arabidopsis</italic>
(TAIR;
<ext-link ext-link-type="uri" xlink:href="http://www.arabidopsis.org">www.arabidopsis.org</ext-link>
; see Unit 1.11). GBrowse_syn is part of the GBrowse software package and can be downloaded from the web and run on any unix-like operating system, such as Linux, Solaris, Mac OS X etc. GBrowse_syn is still under active development. This unit will cover installation and configuration as part of the current stable version of GBrowse (v1.71).</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>

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